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Items: 35


Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T Cells.

Zhang S, Al-Maghout T, Zhou Y, Bissinger R, Abousaab A, Salker MS, Pelzl L, Cobb BS, Cheng A, Singh Y, Lang F.

Cell Physiol Biochem. 2016;39(4):1360-8. doi: 10.1159/000447840. Epub 2016 Sep 8.


MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR.

Singh Y, Garden OA, Lang F, Cobb BS.

J Immunol. 2015 Dec 15;195(12):5667-77. doi: 10.4049/jimmunol.1401875. Epub 2015 Nov 4.


Seasonal variation of depressive symptoms in unipolar major depressive disorder.

Cobb BS, Coryell WH, Cavanaugh J, Keller M, Solomon DA, Endicott J, Potash JB, Fiedorowicz JG.

Compr Psychiatry. 2014 Nov;55(8):1891-9. doi: 10.1016/j.comppsych.2014.07.021. Epub 2014 Aug 4.


Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation.

Ferreirós-Vidal I, Carroll T, Taylor B, Terry A, Liang Z, Bruno L, Dharmalingam G, Khadayate S, Cobb BS, Smale ST, Spivakov M, Srivastava P, Petretto E, Fisher AG, Merkenschlager M.

Blood. 2013 Mar 7;121(10):1769-82. doi: 10.1182/blood-2012-08-450114. Epub 2013 Jan 9.


An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo.

Spruce T, Pernaute B, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M, Rodriguez TA.

Dev Cell. 2010 Aug 17;19(2):207-19. doi: 10.1016/j.devcel.2010.07.014.


Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.

Zhao J, Lee MC, Momin A, Cendan CM, Shepherd ST, Baker MD, Asante C, Bee L, Bethry A, Perkins JR, Nassar MA, Abrahamsen B, Dickenson A, Cobb BS, Merkenschlager M, Wood JN.

J Neurosci. 2010 Aug 11;30(32):10860-71. doi: 10.1523/JNEUROSCI.1980-10.2010.


Runx proteins regulate Foxp3 expression.

Bruno L, Mazzarella L, Hoogenkamp M, Hertweck A, Cobb BS, Sauer S, Hadjur S, Leleu M, Naoe Y, Telfer JC, Bonifer C, Taniuchi I, Fisher AG, Merkenschlager M.

J Exp Med. 2009 Oct 26;206(11):2329-37. doi: 10.1084/jem.20090226. Epub 2009 Oct 19.


Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus.

Hadjur S, Williams LM, Ryan NK, Cobb BS, Sexton T, Fraser P, Fisher AG, Merkenschlager M.

Nature. 2009 Jul 16;460(7253):410-3. doi: 10.1038/nature08079. Epub 2009 May 20.


The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing.

Redrup L, Branco MR, Perdeaux ER, Krueger C, Lewis A, Santos F, Nagano T, Cobb BS, Fraser P, Reik W.

Development. 2009 Feb;136(4):525-30. doi: 10.1242/dev.031328. Epub 2009 Jan 14.


A reappraisal of evidence for probabilistic models of allelic exclusion.

Taylor B, Cobb BS, Bruno L, Webster Z, Fisher AG, Merkenschlager M.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):516-21. doi: 10.1073/pnas.0808764105. Epub 2008 Dec 30.


IL4 blockade of inducible regulatory T cell differentiation: the role of Th2 cells, Gata3 and PU.1.

Hadjur S, Bruno L, Hertweck A, Cobb BS, Taylor B, Fisher AG, Merkenschlager M.

Immunol Lett. 2009 Jan 29;122(1):37-43. doi: 10.1016/j.imlet.2008.11.001. Epub 2008 Nov 29.


Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a.

Nesterova TB, Popova BC, Cobb BS, Norton S, Senner CE, Tang YA, Spruce T, Rodriguez TA, Sado T, Merkenschlager M, Brockdorff N.

Epigenetics Chromatin. 2008 Oct 27;1(1):2. doi: 10.1186/1756-8935-1-2.


T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

Sauer S, Bruno L, Hertweck A, Finlay D, Leleu M, Spivakov M, Knight ZA, Cobb BS, Cantrell D, O'Connor E, Shokat KM, Fisher AG, Merkenschlager M.

Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7797-802. doi: 10.1073/pnas.0800928105. Epub 2008 May 28.


Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage.

Koralov SB, Muljo SA, Galler GR, Krek A, Chakraborty T, Kanellopoulou C, Jensen K, Cobb BS, Merkenschlager M, Rajewsky N, Rajewsky K.

Cell. 2008 Mar 7;132(5):860-74. doi: 10.1016/j.cell.2008.02.020.


Dicer-dependent pathways regulate chondrocyte proliferation and differentiation.

Kobayashi T, Lu J, Cobb BS, Rodda SJ, McMahon AP, Schipani E, Merkenschlager M, Kronenberg HM.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1949-54. doi: 10.1073/pnas.0707900105. Epub 2008 Jan 31.


Cohesins functionally associate with CTCF on mammalian chromosome arms.

Parelho V, Hadjur S, Spivakov M, Leleu M, Sauer S, Gregson HC, Jarmuz A, Canzonetta C, Webster Z, Nesterova T, Cobb BS, Yokomori K, Dillon N, Aragon L, Fisher AG, Merkenschlager M.

Cell. 2008 Feb 8;132(3):422-33. doi: 10.1016/j.cell.2008.01.011. Epub 2008 Jan 31.


The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells.

Jørgensen HF, Azuara V, Amoils S, Spivakov M, Terry A, Nesterova T, Cobb BS, Ramsahoye B, Merkenschlager M, Fisher AG.

Genome Biol. 2007;8(8):R169.


Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.

Thompson EC, Cobb BS, Sabbattini P, Meixlsperger S, Parelho V, Liberg D, Taylor B, Dillon N, Georgopoulos K, Jumaa H, Smale ST, Fisher AG, Merkenschlager M.

Immunity. 2007 Mar;26(3):335-44. Erratum in: Immunity. 2007 Apr;26(4):533.


A role for Dicer in immune regulation.

Cobb BS, Hertweck A, Smith J, O'Connor E, Graf D, Cook T, Smale ST, Sakaguchi S, Livesey FJ, Fisher AG, Merkenschlager M.

J Exp Med. 2006 Oct 30;203(11):2519-27. Epub 2006 Oct 23.


Ikaros-family proteins: in search of molecular functions during lymphocyte development.

Cobb BS, Smale ST.

Curr Top Microbiol Immunol. 2005;290:29-47. Review.


T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer.

Cobb BS, Nesterova TB, Thompson E, Hertweck A, O'Connor E, Godwin J, Wilson CB, Brockdorff N, Fisher AG, Smale ST, Merkenschlager M.

J Exp Med. 2005 May 2;201(9):1367-73.


Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor.

Papathanasiou P, Perkins AC, Cobb BS, Ferrini R, Sridharan R, Hoyne GF, Nelms KA, Smale ST, Goodnow CC.

Immunity. 2003 Jul;19(1):131-44.


A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.

Dovat S, Ronni T, Russell D, Ferrini R, Cobb BS, Smale ST.

Genes Dev. 2002 Dec 1;16(23):2985-90.


Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator.

Trinh LA, Ferrini R, Cobb BS, Weinmann AS, Hahm K, Ernst P, Garraway IP, Merkenschlager M, Smale ST.

Genes Dev. 2001 Jul 15;15(14):1817-32.


Mechanisms of transcriptional regulation in lymphocyte progenitors: insight from an analysis of the terminal transferase promoter.

Ernst P, Hahm K, Cobb BS, Brown KE, Trinh LA, McCarty AS, Merkenschlager M, Klug CA, Fisher AG, Smale ST.

Cold Spring Harb Symp Quant Biol. 1999;64:87-97. Review. No abstract available.


Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding.

Cobb BS, Morales-Alcelay S, Kleiger G, Brown KE, Fisher AG, Smale ST.

Genes Dev. 2000 Sep 1;14(17):2146-60.


Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.

Hahm K, Cobb BS, McCarty AS, Brown KE, Klug CA, Lee R, Akashi K, Weissman IL, Fisher AG, Smale ST.

Genes Dev. 1998 Mar 15;12(6):782-96.


The Ets protein Spi-B is expressed exclusively in B cells and T cells during development.

Su GH, Ip HS, Cobb BS, Lu MM, Chen HM, Simon MC.

J Exp Med. 1996 Jul 1;184(1):203-14.


Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets.

Lipfert L, Haimovich B, Schaller MD, Cobb BS, Parsons JT, Brugge JS.

J Cell Biol. 1992 Nov;119(4):905-12.


pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Schaller MD, Borgman CA, Cobb BS, Vines RR, Reynolds AB, Parsons JT.

Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5192-6.

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