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Items: 1 to 50 of 61

1.

Epigenetic Priming in Immunodeficiencies.

Martínez-Cano J, Campos-Sánchez E, Cobaleda C.

Front Cell Dev Biol. 2019 Jul 10;7:125. doi: 10.3389/fcell.2019.00125. eCollection 2019. Review.

2.

Novel ETV6-RUNX1 Mouse Model to Study the Role of ELF-MF in Childhood B-Acute Lymphoblastic Leukemia: a Pilot Study.

Campos-Sanchez E, Vicente-Dueñas C, Rodríguez-Hernández G, Capstick M, Kuster N, Dasenbrock C, Sánchez-García I, Cobaleda C.

Bioelectromagnetics. 2019 Jul;40(5):343-353. doi: 10.1002/bem.22193. Epub 2019 Jun 3.

PMID:
31157932
3.

Epigenetic Deregulation in Human Primary Immunodeficiencies.

Campos-Sanchez E, Martínez-Cano J, Del Pino Molina L, López-Granados E, Cobaleda C.

Trends Immunol. 2019 Jan;40(1):49-65. doi: 10.1016/j.it.2018.11.005. Epub 2018 Nov 30. Review.

PMID:
30509895
4.

Epigenetic Priming in Cancer Initiation.

Vicente-Dueñas C, Hauer J, Cobaleda C, Borkhardt A, Sánchez-García I.

Trends Cancer. 2018 Jun;4(6):408-417. doi: 10.1016/j.trecan.2018.04.007. Review.

PMID:
29860985
5.

Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases.

Rodríguez-Hernández G, Hauer J, Martín-Lorenzo A, Schäfer D, Bartenhagen C, García-Ramírez I, Auer F, González-Herrero I, Ruiz-Roca L, Gombert M, Okpanyi V, Fischer U, Chen C, Dugas M, Bhatia S, Linka RM, Garcia-Suquia M, Rascón-Trincado MV, Garcia-Sanchez A, Blanco O, García-Cenador MB, García-Criado FJ, Cobaleda C, Alonso-López D, De Las Rivas J, Müschen M, Vicente-Dueñas C, Sánchez-García I, Borkhardt A.

Cancer Res. 2017 Aug 15;77(16):4365-4377. doi: 10.1158/0008-5472.CAN-17-0701. Epub 2017 Jun 19.

6.

Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development.

Campos-Sanchez E, Deleyto-Seldas N, Dominguez V, Carrillo-de-Santa-Pau E, Ura K, Rocha PP, Kim J, Aljoufi A, Esteve-Codina A, Dabad M, Gut M, Heyn H, Kaneda Y, Nimura K, Skok JA, Martinez-Frias ML, Cobaleda C.

Cell Rep. 2017 May 23;19(8):1586-1601. doi: 10.1016/j.celrep.2017.04.069.

7.

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.

Robles EF, Mena-Varas M, Barrio L, Merino-Cortes SV, Balogh P, Du MQ, Akasaka T, Parker A, Roa S, Panizo C, Martin-Guerrero I, Siebert R, Segura V, Agirre X, Macri-Pellizeri L, Aldaz B, Vilas-Zornoza A, Zhang S, Moody S, Calasanz MJ, Tousseyn T, Broccardo C, Brousset P, Campos-Sanchez E, Cobaleda C, Sanchez-Garcia I, Fernandez-Luna JL, Garcia-Muñoz R, Pena E, Bellosillo B, Salar A, Baptista MJ, Hernandez-Rivas JM, Gonzalez M, Terol MJ, Climent J, Ferrandez A, Sagaert X, Melnick AM, Prosper F, Oscier DG, Carrasco YR, Dyer MJ, Martinez-Climent JA.

Nat Commun. 2016 Jun 14;7:11889. doi: 10.1038/ncomms11889.

8.

Comparative dosimetry for children and rodents exposed to extremely low-frequency magnetic fields.

Gong Y, Capstick M, Dasenbrock C, Fedrowitz M, Cobaleda C, Sánchez-García I, Kuster N.

Bioelectromagnetics. 2016 Jul;37(5):310-22. doi: 10.1002/bem.21976. Epub 2016 May 13.

PMID:
27176719
9.

Extremely low-frequency magnetic fields and risk of childhood leukemia: A risk assessment by the ARIMMORA consortium.

Schüz J, Dasenbrock C, Ravazzani P, Röösli M, Schär P, Bounds PL, Erdmann F, Borkhardt A, Cobaleda C, Fedrowitz M, Hamnerius Y, Sanchez-Garcia I, Seger R, Schmiegelow K, Ziegelberger G, Capstick M, Manser M, Müller M, Schmid CD, Schürmann D, Struchen B, Kuster N.

Bioelectromagnetics. 2016 Apr;37(3):183-189. doi: 10.1002/bem.21963. Epub 2016 Mar 15.

PMID:
26991812
10.

GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.

Auer F, Ingenhag D, Bhatia S, Enczmann J, Cobaleda C, Sanchez-Garcia I, Borkhardt A, Hauer J.

Eur J Med Genet. 2016 Mar;59(3):166-72. doi: 10.1016/j.ejmg.2015.11.009. Epub 2015 Nov 26. Review.

PMID:
26626503
11.

Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.

Martín-Lorenzo A, Hauer J, Vicente-Dueñas C, Auer F, González-Herrero I, García-Ramírez I, Ginzel S, Thiele R, Constantinescu SN, Bartenhagen C, Dugas M, Gombert M, Schäfer D, Blanco O, Mayado A, Orfao A, Alonso-López D, Rivas Jde L, Cobaleda C, García-Cenador MB, García-Criado FJ, Sánchez-García I, Borkhardt A.

Cancer Discov. 2015 Dec;5(12):1328-43. doi: 10.1158/2159-8290.CD-15-0892. Epub 2015 Sep 25.

12.

Genetically engineered mouse models of human B-cell precursor leukemias.

Hauer J, Borkhardt A, Sánchez-García I, Cobaleda C.

Cell Cycle. 2014;13(18):2836-46. doi: 10.4161/15384101.2014.949137. Review.

13.

Tumoral reprogramming: Plasticity takes a walk on the wild side.

Campos-Sánchez E, Cobaleda C.

Biochim Biophys Acta. 2015 Apr;1849(4):436-47. doi: 10.1016/j.bbagrm.2014.07.003. Epub 2014 Jul 17. Review.

PMID:
25038581
14.

Childhood leukaemia risks: from unexplained findings near nuclear installations to recommendations for future research.

Laurier D, Grosche B, Auvinen A, Clavel J, Cobaleda C, Dehos A, Hornhardt S, Jacob S, Kaatsch P, Kosti O, Kuehni C, Lightfoot T, Spycher B, Van Nieuwenhuyse A, Wakeford R, Ziegelberger G.

J Radiol Prot. 2014 Sep;34(3):R53-68. doi: 10.1088/0952-4746/34/3/R53. Epub 2014 Jun 18. Review.

15.

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.

Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sanchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I.

Nat Commun. 2014 Jun 2;5:3904. doi: 10.1038/ncomms4904.

16.

Lineage-specific function of Engrailed-2 in the progression of chronic myelogenous leukemia to T-cell blast crisis.

Abollo-Jiménez F, Campos-Sánchez E, Toboso-Navasa A, Vicente-Dueñas C, González-Herrero I, Alonso-Escudero E, González M, Segura V, Blanco O, Martínez-Climent JA, Sánchez-García I, Cobaleda C.

Cell Cycle. 2014;13(11):1717-26. doi: 10.4161/cc.28629. Epub 2014 Mar 25.

17.

Function of oncogenes in cancer development: a changing paradigm.

Vicente-Dueñas C, Romero-Camarero I, Cobaleda C, Sánchez-García I.

EMBO J. 2013 May 29;32(11):1502-13. doi: 10.1038/emboj.2013.97. Epub 2013 Apr 30. Review.

18.

Back to the beginning: The initiation of cancer.

Cobaleda C, Sánchez-García I.

Bioessays. 2013 May;35(5):413. doi: 10.1002/bies.201300024. Epub 2013 Apr 2. No abstract available.

19.

Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation.

Romero-Camarero I, Jiang X, Natkunam Y, Lu X, Vicente-Dueñas C, Gonzalez-Herrero I, Flores T, Garcia JL, McNamara G, Kunder C, Zhao S, Segura V, Fontan L, Martínez-Climent JA, García-Criado FJ, Theis JD, Dogan A, Campos-Sánchez E, Green MR, Alizadeh AA, Cobaleda C, Sánchez-García I, Lossos IS.

Nat Commun. 2013;4:1338. doi: 10.1038/ncomms2334.

20.

The cellular architecture of multiple myeloma.

Vicente-Dueñas C, Romero-Camarero I, García-Criado FJ, Cobaleda C, Sánchez-García I.

Cell Cycle. 2012 Oct 15;11(20):3715-7. doi: 10.4161/cc.22178. Epub 2012 Sep 14. No abstract available.

21.

A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.

Vicente-Dueñas C, Romero-Camarero I, González-Herrero I, Alonso-Escudero E, Abollo-Jiménez F, Jiang X, Gutierrez NC, Orfao A, Marín N, Villar LM, Criado MC, Pintado B, Flores T, Alonso-López D, De Las Rivas J, Jiménez R, Criado FJ, Cenador MB, Lossos IS, Cobaleda C, Sánchez-García I.

EMBO J. 2012 Sep 12;31(18):3704-17. doi: 10.1038/emboj.2012.227. Epub 2012 Aug 17.

22.

MALT lymphoma meets stem cells.

Vicente-Dueñas C, Cobaleda C, Martínez-Climent JÁ, Sánchez-García I.

Cell Cycle. 2012 Aug 15;11(16):2961-2. doi: 10.4161/cc.21264. Epub 2012 Jul 24. No abstract available.

23.

Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice.

Vicente-Dueñas C, Fontán L, Gonzalez-Herrero I, Romero-Camarero I, Segura V, Aznar MA, Alonso-Escudero E, Campos-Sanchez E, Ruiz-Roca L, Barajas-Diego M, Sagardoy A, Martinez-Ferrandis JI, Abollo-Jimenez F, Bertolo C, Peñuelas I, Garcia-Criado FJ, García-Cenador MB, Tousseyn T, Agirre X, Prosper F, Garcia-Bragado F, McPhail ED, Lossos IS, Du MQ, Flores T, Hernandez-Rivas JM, Gonzalez M, Salar A, Bellosillo B, Conde E, Siebert R, Sagaert X, Cobaleda C, Sanchez-Garcia I, Martinez-Climent JA.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10534-9. doi: 10.1073/pnas.1204127109. Epub 2012 Jun 11.

24.

Acute lymphoblastic leukemia and developmental biology: a crucial interrelationship.

Campos-Sanchez E, Toboso-Navasa A, Romero-Camarero I, Barajas-Diego M, Sanchez-García I, Cobaleda C.

Cell Cycle. 2011 Oct 15;10(20):3473-86. doi: 10.4161/cc.10.20.17779. Epub 2011 Oct 15. Review.

25.

Stem cell aging and cancer: immortal but vulnerable.

Cobaleda C, Sanchez-García I.

Cell Cycle. 2011 Sep 1;10(17):2823-4. Epub 2011 Sep 1. No abstract available.

26.

The age of the target cell affects B-cell leukaemia malignancy.

Vicente-Dueñas C, Abollo-Jiménez F, Ruiz-Roca L, Alonso-Escudero E, Jiménez R, Cenador MB, Criado FJ, Cobaleda C, Sánchez-García I.

Aging (Albany NY). 2010 Dec;2(12):908-13.

27.

Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia.

Virely C, Moulin S, Cobaleda C, Lasgi C, Alberdi A, Soulier J, Sigaux F, Chan S, Kastner P, Ghysdael J.

Leukemia. 2010 Jun;24(6):1200-4. doi: 10.1038/leu.2010.63. Epub 2010 Apr 15. No abstract available.

PMID:
20393504
28.

Reprogramming of B cells.

Cobaleda C.

Methods Mol Biol. 2010;636:233-50. doi: 10.1007/978-1-60761-691-7_15.

PMID:
20336527
29.

Bcl2 is not required for the development and maintenance of leukemia stem cells in mice.

González-Herrero I, Vicente-Dueñas C, Orfao A, Flores T, Jiménez R, Cobaleda C, Sánchez-García I.

Carcinogenesis. 2010 Jul;31(7):1292-7. doi: 10.1093/carcin/bgq062. Epub 2010 Mar 18.

30.

The evolution of cancer modeling: the shadow of stem cells.

Vicente-Dueñas C, Cobaleda C, Pérez-Losada J, Sánchez-García I.

Dis Model Mech. 2010 Mar-Apr;3(3-4):149-55. doi: 10.1242/dmm.002774.

31.

Physiological cellular reprogramming and cancer.

Abollo-Jiménez F, Jiménez R, Cobaleda C.

Semin Cancer Biol. 2010 Apr;20(2):98-106. doi: 10.1016/j.semcancer.2010.02.002. Epub 2010 Feb 24. Review.

PMID:
20188173
32.

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.

Malin S, McManus S, Cobaleda C, Novatchkova M, Delogu A, Bouillet P, Strasser A, Busslinger M.

Nat Immunol. 2010 Feb;11(2):171-9. doi: 10.1038/ni.1827. Epub 2009 Nov 29.

33.

Effect of an antioxidant functional food beverage on exercise-induced oxidative stress: a long-term and large-scale clinical intervention study.

Muñoz ME, Galan AI, Palacios E, Diez MA, Muguerza B, Cobaleda C, Calvo JI, Aruoma OI, Sanchez-Garcia I, Jimenez R.

Toxicology. 2010 Nov 28;278(1):101-11. doi: 10.1016/j.tox.2009.10.015. Epub 2009 Oct 24.

PMID:
19857542
34.

The role of cellular plasticity in cancer development.

Vicente-Dueñas C, Gutiérrez de Diego J, Rodríguez FD, Jiménez R, Cobaleda C.

Curr Med Chem. 2009;16(28):3676-85. Review.

PMID:
19747147
35.

B-cell acute lymphoblastic leukaemia: towards understanding its cellular origin.

Cobaleda C, Sánchez-García I.

Bioessays. 2009 Jun;31(6):600-9. doi: 10.1002/bies.200800234. Review.

PMID:
19444834
36.

Stem-cell driven cancer: "hands-off" regulation of cancer development.

Vicente-Dueñas C, Pérez-Caro M, Abollo-Jiménez F, Cobaleda C, Sánchez-García I.

Cell Cycle. 2009 May 1;8(9):1314-8. Epub 2009 May 18.

37.

Cancer induction by restriction of oncogene expression to the stem cell compartment.

Pérez-Caro M, Cobaleda C, González-Herrero I, Vicente-Dueñas C, Bermejo-Rodríguez C, Sánchez-Beato M, Orfao A, Pintado B, Flores T, Sánchez-Martín M, Jiménez R, Piris MA, Sánchez-García I.

EMBO J. 2009 Jan 7;28(1):8-20. doi: 10.1038/emboj.2008.253. Epub 2008 Nov 27.

38.

Players in human liposarcoma: JUN joins the cast.

Cobaleda C, Jimenez R, Sanchez-Garcia I.

Cancer Biol Ther. 2008 Aug;7(8):1302-4. Epub 2008 Aug 9. No abstract available.

PMID:
18708756
39.

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development.

Kwon K, Hutter C, Sun Q, Bilic I, Cobaleda C, Malin S, Busslinger M.

Immunity. 2008 Jun;28(6):751-62. doi: 10.1016/j.immuni.2008.04.014.

40.

Developmental plasticity of lymphocytes.

Cobaleda C, Busslinger M.

Curr Opin Immunol. 2008 Apr;20(2):139-48. doi: 10.1016/j.coi.2008.03.017. Epub 2008 May 9. Review.

PMID:
18472258
41.

The Emerging Picture of Human Breast Cancer as a Stem Cell-based Disease.

Cobaleda C, Cruz JJ, González-Sarmiento R, Sánchez-García I, Pérez-Losada J.

Stem Cell Rev. 2008 Summer;4(2):67-79. doi: 10.1007/s12015-008-9012-6. Review.

PMID:
18401767
42.

The theoretical basis of cancer-stem-cell-based therapeutics of cancer: can it be put into practice?

Sánchez-García I, Vicente-Dueñas C, Cobaleda C.

Bioessays. 2007 Dec;29(12):1269-80. Review.

PMID:
18022789
43.

Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.

Cobaleda C, Jochum W, Busslinger M.

Nature. 2007 Sep 27;449(7161):473-7. Epub 2007 Sep 12.

PMID:
17851532
44.

Function of the zinc-finger transcription factor SNAI2 in cancer and development.

Cobaleda C, Pérez-Caro M, Vicente-Dueñas C, Sánchez-García I.

Annu Rev Genet. 2007;41:41-61. Review.

PMID:
17550342
45.

Pax5: the guardian of B cell identity and function.

Cobaleda C, Schebesta A, Delogu A, Busslinger M.

Nat Immunol. 2007 May;8(5):463-70. Review.

PMID:
17440452
46.

Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA factors.

Heavey B, Charalambous C, Cobaleda C, Busslinger M.

EMBO J. 2003 Aug 1;22(15):3887-97.

47.

Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.

Souabni A, Cobaleda C, Schebesta M, Busslinger M.

Immunity. 2002 Dec;17(6):781-93.

48.

Selective destruction of tumor cells through specific inhibition of products resulting from chromosomal translocations.

Rodriguez-García A, Sánchez-Martín M, Pérez-Losada J, Pérez-Mancera PA, Sagrera-Aparisi A, Gutiérrez-Cianca N, Cobaleda C, Sánchez-García I.

Curr Cancer Drug Targets. 2001 Aug;1(2):109-19. Review.

PMID:
12188884
49.

Fusogenic activity of reconstituted newcastle disease virus envelopes: a role for the hemagglutinin-neuraminidase protein in the fusion process.

Cobaleda C, Muñoz-Barroso I, Sagrera A, Villar E.

Int J Biochem Cell Biol. 2002 Apr;34(4):403-13.

PMID:
11854039
50.

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