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Items: 40


Respective contribution of cytosolic phospholipase A2α and secreted phospholipase A2 IIA to inflammation and eicosanoid production in arthritis.

Duchez AC, Boudreau LH, Naika GS, Rousseau M, Cloutier N, Levesque T, Gelb MH, Boilard E.

Prostaglandins Other Lipid Mediat. 2019 Aug;143:106340. doi: 10.1016/j.prostaglandins.2019.106340. Epub 2019 May 23.


Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestations.

Becker Y, Loignon RC, Julien AS, Marcoux G, Allaeys I, Lévesque T, Rollet-Labelle E, Benk-Fortin H, Cloutier N, Melki I, Eder L, Wagner É, Pelletier M, Hajj HE, Tremblay MÈ, Belleannée C, Hébert MJ, Dieudé M, Rauch J, Fortin PR, Boilard E.

Sci Rep. 2019 Mar 14;9(1):4530. doi: 10.1038/s41598-019-40900-3.


Differential attenuation of β2 integrin-dependent and -independent neutrophil migration by Ly6G ligation.

Cunin P, Lee PY, Kim E, Schmider AB, Cloutier N, Pare A, Gunzer M, Soberman RJ, Lacroix S, Boilard E, Lefort CT, Nigrovic PA.

Blood Adv. 2019 Feb 12;3(3):256-267. doi: 10.1182/bloodadvances.2018026732.


Platelet abnormalities in Huntington's disease.

Denis HL, Lamontagne-Proulx J, St-Amour I, Mason SL, Rowley JW, Cloutier N, Tremblay MÈ, Vincent AT, Gould PV, Chouinard S, Weyrich AS, Rondina MT, Barker RA, Boilard E, Cicchetti F.

J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):272-283. doi: 10.1136/jnnp-2018-318854. Epub 2018 Dec 19.


Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease.

Lamontagne-Proulx J, St-Amour I, Labib R, Pilon J, Denis HL, Cloutier N, Roux-Dalvai F, Vincent AT, Mason SL, Williams-Gray C, Duchez AC, Droit A, Lacroix S, Dupré N, Langlois M, Chouinard S, Panisset M, Barker RA, Boilard E, Cicchetti F.

Neurobiol Dis. 2019 Apr;124:163-175. doi: 10.1016/j.nbd.2018.11.002. Epub 2018 Nov 5.


Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.

Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1550-E1559. doi: 10.1073/pnas.1720553115. Epub 2018 Jan 31.


Challenges and Opportunities in Enabling High-Throughput, Miniaturized High Content Screening.

Nickischer D, Elkin L, Cloutier N, O'Connell J, Banks M, Weston A.

Methods Mol Biol. 2018;1683:165-191. doi: 10.1007/978-1-4939-7357-6_11.


Presence of diabetes autoantigens in extracellular vesicles derived from human islets.

Hasilo CP, Negi S, Allaeys I, Cloutier N, Rutman AK, Gasparrini M, Bonneil É, Thibault P, Boilard É, Paraskevas S.

Sci Rep. 2017 Jul 10;7(1):5000. doi: 10.1038/s41598-017-04977-y.


Distinct Subtypes of Microparticle-containing Immune Complexes Are Associated with Disease Activity, Damage, and Carotid Intima-media Thickness in Systemic Lupus Erythematosus.

Fortin PR, Cloutier N, Bissonnette V, Aghdassi E, Eder L, Simonyan D, Laflamme N, Boilard E.

J Rheumatol. 2016 Nov;43(11):2019-2025. Epub 2016 Sep 1.


Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses.

Marcoux G, Duchez AC, Cloutier N, Provost P, Nigrovic PA, Boilard E.

Sci Rep. 2016 Oct 27;6:35928. doi: 10.1038/srep35928.


Identification of Shigella flexneri isolates carrying the Shiga toxin 1-producing gene in Quebec, Canada, linked to travel to Haiti.

Bekal S, Pilon PA, Cloutier N, Doualla-Bell F, Longtin J.

Can J Microbiol. 2015 Dec;61(12):995-6. doi: 10.1139/cjm-2015-0538. Epub 2015 Sep 10. No abstract available.


Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA.

Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannée C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Lévesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3564-73. doi: 10.1073/pnas.1507905112. Epub 2015 Jun 23. Erratum in: Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):E6825. Naika, Gajendra S [added].


Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment.

Rousseau M, Belleannee C, Duchez AC, Cloutier N, Levesque T, Jacques F, Perron J, Nigrovic PA, Dieude M, Hebert MJ, Gelb MH, Boilard E.

PLoS One. 2015 Jan 14;10(1):e0116812. doi: 10.1371/journal.pone.0116812. eCollection 2015.


Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation.

Boudreau LH, Duchez AC, Cloutier N, Soulet D, Martin N, Bollinger J, Paré A, Rousseau M, Naika GS, Lévesque T, Laflamme C, Marcoux G, Lambeau G, Farndale RW, Pouliot M, Hamzeh-Cognasse H, Cognasse F, Garraud O, Nigrovic PA, Guderley H, Lacroix S, Thibault L, Semple JW, Gelb MH, Boilard E.

Blood. 2014 Oct 2;124(14):2173-83. doi: 10.1182/blood-2014-05-573543. Epub 2014 Jul 31.


Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation.

Boilard E, Paré G, Rousseau M, Cloutier N, Dubuc I, Lévesque T, Borgeat P, Flamand L.

Blood. 2014 May 1;123(18):2854-63. doi: 10.1182/blood-2013-07-515536. Epub 2014 Mar 24.


Evidence of impairment of normal inflammatory reaction by a high-fat diet.

Laflamme C, Bertheau-Mailhot G, Giambelluca MS, Cloutier N, Boilard E, Pouliot M.

Genes Immun. 2014 Apr;15(4):224-32. doi: 10.1038/gene.2014.8. Epub 2014 Feb 27.


Expression and regulation of glycogen synthase kinase 3 in human neutrophils.

Giambelluca MS, Cloutier N, Rollet-Labelle E, Boilard E, Pouliot M.

Int J Biochem Cell Biol. 2013 Nov;45(11):2660-5. doi: 10.1016/j.biocel.2013.09.001. Epub 2013 Sep 10.


Activated platelets can deliver mRNA regulatory Ago2•microRNA complexes to endothelial cells via microparticles.

Laffont B, Corduan A, Plé H, Duchez AC, Cloutier N, Boilard E, Provost P.

Blood. 2013 Jul 11;122(2):253-61. doi: 10.1182/blood-2013-03-492801. Epub 2013 May 7.


The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes.

Cloutier N, Tan S, Boudreau LH, Cramb C, Subbaiah R, Lahey L, Albert A, Shnayder R, Gobezie R, Nigrovic PA, Farndale RW, Robinson WH, Brisson A, Lee DM, Boilard E.

EMBO Mol Med. 2013 Feb;5(2):235-49. doi: 10.1002/emmm.201201846. Epub 2012 Dec 11.


Platelets can enhance vascular permeability.

Cloutier N, Paré A, Farndale RW, Schumacher HR, Nigrovic PA, Lacroix S, Boilard E.

Blood. 2012 Aug 9;120(6):1334-43. doi: 10.1182/blood-2012-02-413047. Epub 2012 Apr 27.


HCS road: an enterprise system for integrated HCS data management and analysis.

Jackson D, Lenard M, Zelensky A, Shaikh M, Scharpf JV, Shaginaw R, Nawade M, Agler M, Cloutier NJ, Fennell M, Guo Q, Wardwell-Swanson J, Zhao D, Zhu Y, Miller C, Gill J.

J Biomol Screen. 2010 Aug;15(7):882-91. doi: 10.1177/1087057110374233. Epub 2010 Jul 16.


Best practices in compound management for preserving compound integrity and accurately providing samples for assays.

Matson SL, Chatterjee M, Stock DA, Leet JE, Dumas EA, Ferrante CD, Monahan WE, Cook LS, Watson J, Cloutier NJ, Ferrante MA, Houston JG, Banks MN.

J Biomol Screen. 2009 Jun;14(5):476-84. doi: 10.1177/1087057109336593. Epub 2009 May 29.


Increased tumorigenicity of cells carrying recombinant human herpesvirus 8.

Cloutier N, van Eyll O, Janelle ME, Lefort S, Gao SJ, Flamand L.

Arch Virol. 2008;153(1):93-103. Epub 2007 Oct 18.


Albumin binding, relaxivity, and water exchange kinetics of the diastereoisomers of MS-325, a gadolinium(III)-based magnetic resonance angiography contrast agent.

Caravan P, Parigi G, Chasse JM, Cloutier NJ, Ellison JJ, Lauffer RB, Luchinat C, McDermid SA, Spiller M, McMurry TJ.

Inorg Chem. 2007 Aug 6;46(16):6632-9. Epub 2007 Jul 11.


When are two waters worse than one? Doubling the hydration number of a Gd-DTPA derivative decreases relaxivity.

Caravan P, Amedio JC Jr, Dunham SU, Greenfield MT, Cloutier NJ, McDermid SA, Spiller M, Zech SG, Looby RJ, Raitsimring AM, McMurry TJ, Lauffer RB.

Chemistry. 2005 Oct 7;11(20):5866-74.


Characterization of human herpesvirus 6 variant B immediate-early 1 protein modifications by small ubiquitin-related modifiers.

Gravel A, Dion V, Cloutier N, Gosselin J, Flamand L.

J Gen Virol. 2004 May;85(Pt 5):1319-28.


Characterization of the immediate-early 2 protein of human herpesvirus 6, a promiscuous transcriptional activator.

Gravel A, Tomoiu A, Cloutier N, Gosselin J, Flamand L.

Virology. 2003 Apr 10;308(2):340-53.


Quantification of human herpesvirus 8 by real-time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease.

Boivin G, Côté S, Cloutier N, Abed Y, Maguigad M, Routy JP.

J Med Virol. 2002 Nov;68(3):399-403.


The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates.

Caravan P, Cloutier NJ, Greenfield MT, McDermid SA, Dunham SU, Bulte JW, Amedio JC Jr, Looby RJ, Supkowski RM, Horrocks WD Jr, McMurry TJ, Lauffer RB.

J Am Chem Soc. 2002 Mar 27;124(12):3152-62.


Cytochrome P-450scc-mediated oxidation of (20S)-22-thiacholesterol: characterization of mechanism-based inhibition.

Miao E, Joardar S, Zuo C, Cloutier NJ, Nagahisa A, Byon C, Wilson SR, Orme-Johnson WH.

Biochemistry. 1995 Jul 4;34(26):8415-21.


Transient induction of tryptophan decarboxylase (TDC) and strictosidine synthase (SS) genes in cell suspension cultures of Catharanthus roseus.

Roewer IA, Cloutier N, Nessler CL, De Luca V.

Plant Cell Rep. 1992 Mar;11(2):86-9. doi: 10.1007/BF00235259.


Ra-226 concentrations in otter, Lutra canadensis, trapped near uranium tailings at Elliot Lake, Ontario.

Wren CD, Cloutier NR, Lim TP, Dave NK.

Bull Environ Contam Toxicol. 1987 Feb;38(2):209-12. No abstract available.


Transfer coefficient of 226Ra from food to young weaned meadow voles, Microtus pennsylvanicus, in the laboratory.

Burns B, Clulow FV, Cloutier NR, Davé NK, Lim TP.

Health Phys. 1987 Feb;52(2):207-11. No abstract available.


Transfer coefficient of 226Ra from vegetation to meadow voles, Microtus pennsylvanicus, on U mill tailings.

Cloutier NR, Clulow FV, Lim TP, Davé NK.

Health Phys. 1986 Jun;50(6):775-80.


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