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Items: 1 to 50 of 574

1.

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.

Dijkstra KK, Cattaneo CM, Weeber F, Chalabi M, van de Haar J, Fanchi LF, Slagter M, van der Velden DL, Kaing S, Kelderman S, van Rooij N, van Leerdam ME, Depla A, Smit EF, Hartemink KJ, de Groot R, Wolkers MC, Sachs N, Snaebjornsson P, Monkhorst K, Haanen J, Clevers H, Schumacher TN, Voest EE.

Cell. 2018 Aug 3. pii: S0092-8674(18)30903-6. doi: 10.1016/j.cell.2018.07.009. [Epub ahead of print]

PMID:
30100188
2.

Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient.

Beumer J, Artegiani B, Post Y, Reimann F, Gribble F, Nguyen TN, Zeng H, Van den Born M, Van Es JH, Clevers H.

Nat Cell Biol. 2018 Aug;20(8):909-916. doi: 10.1038/s41556-018-0143-y. Epub 2018 Jul 23.

PMID:
30038251
3.

Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures.

Hui KPY, Ching RHH, Chan SKH, Nicholls JM, Sachs N, Clevers H, Peiris JSM, Chan MCW.

Lancet Respir Med. 2018 Jul 9. pii: S2213-2600(18)30236-4. doi: 10.1016/S2213-2600(18)30236-4. [Epub ahead of print]

PMID:
30001996
4.

Establishment and characterization of a canine keratinocyte organoid culture system.

Wiener DJ, Basak O, Asra P, Boonekamp KE, Kretzschmar K, Papaspyropoulos A, Clevers H.

Vet Dermatol. 2018 Jul 2. doi: 10.1111/vde.12541. [Epub ahead of print]

PMID:
29963730
5.

Modelling Cryptosporidium infection in human small intestinal and lung organoids.

Heo I, Dutta D, Schaefer DA, Iakobachvili N, Artegiani B, Sachs N, Boonekamp KE, Bowden G, Hendrickx APA, Willems RJL, Peters PJ, Riggs MW, O'Connor R, Clevers H.

Nat Microbiol. 2018 Jul;3(7):814-823. doi: 10.1038/s41564-018-0177-8. Epub 2018 Jun 25.

PMID:
29946163
6.

Differentiated human airway organoids to assess infectivity of emerging influenza virus.

Zhou J, Li C, Sachs N, Chiu MC, Wong BH, Chu H, Poon VK, Wang D, Zhao X, Wen L, Song W, Yuan S, Wong KK, Chan JF, To KK, Chen H, Clevers H, Yuen KY.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6822-6827. doi: 10.1073/pnas.1806308115. Epub 2018 Jun 11.

7.

Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.

Tiriac H, Belleau P, Engle DD, Plenker D, Deschênes A, Somerville TDD, Froeling FEM, Burkhart RA, Denroche RE, Jang GH, Miyabayashi K, Young CM, Patel H, Ma M, LaComb JF, Palmaira RLD, Javed AA, Huynh JC, Johnson M, Arora K, Robine N, Shah M, Sanghvi R, Goetz AB, Lowder CY, Martello L, Driehuis E, LeComte N, Askan G, Iacobuzio-Donahue CA, Clevers H, Wood LD, Hruban RH, Thompson E, Aguirre AJ, Wolpin BM, Sasson A, Kim J, Wu M, Bucobo JC, Allen P, Sejpal DV, Nealon W, Sullivan JD, Winter JM, Gimotty PA, Grem JL, DiMaio DJ, Buscaglia JM, Grandgenett PM, Brody JR, Hollingsworth MA, O'Kane GM, Notta F, Kim E, Crawford JM, Devoe C, Ocean A, Wolfgang CL, Yu KH, Li E, Vakoc CR, Hubert B, Fischer SE, Wilson JM, Moffitt R, Knox J, Krasnitz A, Gallinger S, Tuveson DA.

Cancer Discov. 2018 May 31. doi: 10.1158/2159-8290.CD-18-0349. [Epub ahead of print]

PMID:
29853643
8.

Bioengineered bile ducts recapitulate key cholangiocyte functions.

Chen C, Jochems PGM, Salz L, Schneeberger K, Penning LC, van de Graaf SFJ, Beuers U, Clevers H, Geijsen N, Masereeuw R, Spee B.

Biofabrication. 2018 Jun 12;10(3):034103. doi: 10.1088/1758-5090/aac8fd.

PMID:
29848792
9.

Use and application of 3D-organoid technology.

Artegiani B, Clevers H.

Hum Mol Genet. 2018 Aug 1;27(R2):R99-R107. doi: 10.1093/hmg/ddy187.

PMID:
29796608
10.

Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche.

Chakrabarti R, Celià-Terrassa T, Kumar S, Hang X, Wei Y, Choudhury A, Hwang J, Peng J, Nixon B, Grady JJ, DeCoste C, Gao J, van Es JH, Li MO, Aifantis I, Clevers H, Kang Y.

Science. 2018 Jun 29;360(6396). pii: eaan4153. doi: 10.1126/science.aan4153. Epub 2018 May 17.

PMID:
29773667
11.

Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice.

Grinenko T, Eugster A, Thielecke L, Ramasz B, Krüger A, Dietz S, Glauche I, Gerbaulet A, von Bonin M, Basak O, Clevers H, Chavakis T, Wielockx B.

Nat Commun. 2018 May 15;9(1):1898. doi: 10.1038/s41467-018-04188-7.

12.

Enterovirus 71 infection of human airway organoids reveals VP1-145 as a viral infectivity determinant.

van der Sanden SMG, Sachs N, Koekkoek SM, Koen G, Pajkrt D, Clevers H, Wolthers KC.

Emerg Microbes Infect. 2018 May 9;7(1):84. doi: 10.1038/s41426-018-0077-2.

13.

Expanding Impact of Stem Cell Science.

Clevers H.

Stem Cell Reports. 2018 May 8;10(5):1427-1428. doi: 10.1016/j.stemcr.2018.04.017. No abstract available.

14.

ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.

Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes DT, Suzuki M, Burdine RD, Cong F, Koo BK, Clevers H, Stévant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):5474-5479. doi: 10.1073/pnas.1801223115. Epub 2018 May 7.

15.

Organoids in cancer research.

Drost J, Clevers H.

Nat Rev Cancer. 2018 Jul;18(7):407-418. doi: 10.1038/s41568-018-0007-6. Review.

PMID:
29692415
16.

Intra-tumour diversification in colorectal cancer at the single-cell level.

Roerink SF, Sasaki N, Lee-Six H, Young MD, Alexandrov LB, Behjati S, Mitchell TJ, Grossmann S, Lightfoot H, Egan DA, Pronk A, Smakman N, van Gorp J, Anderson E, Gamble SJ, Alder C, van de Wetering M, Campbell PJ, Stratton MR, Clevers H.

Nature. 2018 Apr;556(7702):457-462. doi: 10.1038/s41586-018-0024-3. Epub 2018 Apr 11.

PMID:
29643510
17.

Automated brightfield morphometry of 3D organoid populations by OrganoSeg.

Borten MA, Bajikar SS, Sasaki N, Clevers H, Janes KA.

Sci Rep. 2018 Mar 28;8(1):5319. doi: 10.1038/s41598-017-18815-8.

18.

Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential.

Loomans CJM, Williams Giuliani N, Balak J, Ringnalda F, van Gurp L, Huch M, Boj SF, Sato T, Kester L, de Sousa Lopes SMC, Roost MS, Bonner-Weir S, Engelse MA, Rabelink TJ, Heimberg H, Vries RGJ, van Oudenaarden A, Carlotti F, Clevers H, de Koning EJP.

Stem Cell Reports. 2018 Mar 13;10(3):712-724. doi: 10.1016/j.stemcr.2018.02.005.

19.

Defining Adult Stem Cells by Function, not by Phenotype.

Clevers H, Watt FM.

Annu Rev Biochem. 2018 Jun 20;87:1015-1027. doi: 10.1146/annurev-biochem-062917-012341. Epub 2018 Mar 1.

PMID:
29494240
20.

Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy.

Basak O, Krieger TG, Muraro MJ, Wiebrands K, Stange DE, Frias-Aldeguer J, Rivron NC, van de Wetering M, van Es JH, van Oudenaarden A, Simons BD, Clevers H.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E610-E619. doi: 10.1073/pnas.1715911114. Epub 2018 Jan 8.

21.

Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models.

Linnekamp JF, Hooff SRV, Prasetyanti PR, Kandimalla R, Buikhuisen JY, Fessler E, Ramesh P, Lee KAST, Bochove GGW, de Jong JH, Cameron K, Leersum RV, Rodermond HM, Franitza M, Nürnberg P, Mangiapane LR, Wang X, Clevers H, Vermeulen L, Stassi G, Medema JP.

Cell Death Differ. 2018 Mar;25(3):616-633. doi: 10.1038/s41418-017-0011-5. Epub 2018 Jan 5.

PMID:
29305587
22.

Imaging organoids: a bright future ahead.

Rios AC, Clevers H.

Nat Methods. 2018 Jan 3;15(1):24-26. doi: 10.1038/nmeth.4537.

PMID:
29298292
23.

BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance.

Duarte AA, Gogola E, Sachs N, Barazas M, Annunziato S, R de Ruiter J, Velds A, Blatter S, Houthuijzen JM, van de Ven M, Clevers H, Borst P, Jonkers J, Rottenberg S.

Nat Methods. 2018 Feb;15(2):134-140. doi: 10.1038/nmeth.4535. Epub 2017 Dec 11.

PMID:
29256493
24.

A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche.

Artegiani B, Lyubimova A, Muraro M, van Es JH, van Oudenaarden A, Clevers H.

Cell Rep. 2017 Dec 12;21(11):3271-3284. doi: 10.1016/j.celrep.2017.11.050.

25.

Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney.

Schutgens F, Rookmaaker MB, Blokzijl F, van Boxtel R, Vries R, Cuppen E, Verhaar MC, Clevers H.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11190-E11198. doi: 10.1073/pnas.1714145115. Epub 2017 Dec 13.

26.

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.

Sachs N, de Ligt J, Kopper O, Gogola E, Bounova G, Weeber F, Balgobind AV, Wind K, Gracanin A, Begthel H, Korving J, van Boxtel R, Duarte AA, Lelieveld D, van Hoeck A, Ernst RF, Blokzijl F, Nijman IJ, Hoogstraat M, van de Ven M, Egan DA, Zinzalla V, Moll J, Boj SF, Voest EE, Wessels L, van Diest PJ, Rottenberg S, Vries RGJ, Cuppen E, Clevers H.

Cell. 2018 Jan 11;172(1-2):373-386.e10. doi: 10.1016/j.cell.2017.11.010. Epub 2017 Dec 7.

PMID:
29224780
27.

Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures.

Jager M, Blokzijl F, Sasselli V, Boymans S, Janssen R, Besselink N, Clevers H, van Boxtel R, Cuppen E.

Nat Protoc. 2018 Jan;13(1):59-78. doi: 10.1038/nprot.2017.111. Epub 2017 Dec 7.

PMID:
29215633
28.

Syndecan-1 promotes Wnt/β-catenin signaling in multiple myeloma by presenting Wnts and R-spondins.

Ren Z, van Andel H, de Lau W, Hartholt RB, Maurice MM, Clevers H, Kersten MJ, Spaargaren M, Pals ST.

Blood. 2018 Mar 1;131(9):982-994. doi: 10.1182/blood-2017-07-797050. Epub 2017 Dec 6.

PMID:
29212806
29.

The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.

30.

Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.

Andersson ER, Chivukula IV, Hankeova S, Sjöqvist M, Tsoi YL, Ramsköld D, Masek J, Elmansuri A, Hoogendoorn A, Vazquez E, Storvall H, Netušilová J, Huch M, Fischler B, Ellis E, Contreras A, Nemeth A, Chien KC, Clevers H, Sandberg R, Bryja V, Lendahl U.

Gastroenterology. 2018 Mar;154(4):1080-1095. doi: 10.1053/j.gastro.2017.11.002. Epub 2017 Nov 21.

31.

Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S.

Nat Med. 2017 Nov 7;23(11):1384. doi: 10.1038/nm1117-1384d.

PMID:
29117169
32.

Distinct Cellular Basis for Early Cardiac Arrhythmias, the Cardinal Manifestation of Arrhythmogenic Cardiomyopathy, and the Skin Phenotype of Cardiocutaneous Syndromes.

Karmouch J, Zhou QQ, Miyake CY, Lombardi R, Kretzschmar K, Bannier-Hélaouët M, Clevers H, Wehrens XHT, Willerson JT, Marian AJ.

Circ Res. 2017 Dec 8;121(12):1346-1359. doi: 10.1161/CIRCRESAHA.117.311876. Epub 2017 Oct 10.

PMID:
29018034
33.

Cancer stem cells revisited.

Batlle E, Clevers H.

Nat Med. 2017 Oct 6;23(10):1124-1134. doi: 10.1038/nm.4409. Review.

PMID:
28985214
34.

Interrogating open issues in cancer medicine with patient-derived xenografts.

Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L.

Nat Rev Cancer. 2017 Sep 15;17(10):632. doi: 10.1038/nrc.2017.85. [Epub ahead of print]

PMID:
28912576
35.

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.

Drost J, van Boxtel R, Blokzijl F, Mizutani T, Sasaki N, Sasselli V, de Ligt J, Behjati S, Grolleman JE, van Wezel T, Nik-Zainal S, Kuiper RP, Cuppen E, Clevers H.

Science. 2017 Oct 13;358(6360):234-238. doi: 10.1126/science.aao3130. Epub 2017 Sep 14.

36.

FANTOM5 CAGE profiles of human and mouse samples.

Noguchi S, Arakawa T, Fukuda S, Furuno M, Hasegawa A, Hori F, Ishikawa-Kato S, Kaida K, Kaiho A, Kanamori-Katayama M, Kawashima T, Kojima M, Kubosaki A, Manabe RI, Murata M, Nagao-Sato S, Nakazato K, Ninomiya N, Nishiyori-Sueki H, Noma S, Saijyo E, Saka A, Sakai M, Simon C, Suzuki N, Tagami M, Watanabe S, Yoshida S, Arner P, Axton RA, Babina M, Baillie JK, Barnett TC, Beckhouse AG, Blumenthal A, Bodega B, Bonetti A, Briggs J, Brombacher F, Carlisle AJ, Clevers HC, Davis CA, Detmar M, Dohi T, Edge ASB, Edinger M, Ehrlund A, Ekwall K, Endoh M, Enomoto H, Eslami A, Fagiolini M, Fairbairn L, Farach-Carson MC, Faulkner GJ, Ferrai C, Fisher ME, Forrester LM, Fujita R, Furusawa JI, Geijtenbeek TB, Gingeras T, Goldowitz D, Guhl S, Guler R, Gustincich S, Ha TJ, Hamaguchi M, Hara M, Hasegawa Y, Herlyn M, Heutink P, Hitchens KJ, Hume DA, Ikawa T, Ishizu Y, Kai C, Kawamoto H, Kawamura YI, Kempfle JS, Kenna TJ, Kere J, Khachigian LM, Kitamura T, Klein S, Klinken SP, Knox AJ, Kojima S, Koseki H, Koyasu S, Lee W, Lennartsson A, Mackay-Sim A, Mejhert N, Mizuno Y, Morikawa H, Morimoto M, Moro K, Morris KJ, Motohashi H, Mummery CL, Nakachi Y, Nakahara F, Nakamura T, Nakamura Y, Nozaki T, Ogishima S, Ohkura N, Ohno H, Ohshima M, Okada-Hatakeyama M, Okazaki Y, Orlando V, Ovchinnikov DA, Passier R, Patrikakis M, Pombo A, Pradhan-Bhatt S, Qin XY, Rehli M, Rizzu P, Roy S, Sajantila A, Sakaguchi S, Sato H, Satoh H, Savvi S, Saxena A, Schmidl C, Schneider C, Schulze-Tanzil GG, Schwegmann A, Sheng G, Shin JW, Sugiyama D, Sugiyama T, Summers KM, Takahashi N, Takai J, Tanaka H, Tatsukawa H, Tomoiu A, Toyoda H, van de Wetering M, van den Berg LM, Verardo R, Vijayan D, Wells CA, Winteringham LN, Wolvetang E, Yamaguchi Y, Yamamoto M, Yanagi-Mizuochi C, Yoneda M, Yonekura Y, Zhang PG, Zucchelli S, Abugessaisa I, Arner E, Harshbarger J, Kondo A, Lassmann T, Lizio M, Sahin S, Sengstag T, Severin J, Shimoji H, Suzuki M, Suzuki H, Kawai J, Kondo N, Itoh M, Daub CO, Kasukawa T, Kawaji H, Carninci P, Forrest ARR, Hayashizaki Y.

Sci Data. 2017 Aug 29;4:170112. doi: 10.1038/sdata.2017.112.

37.

Organoid culture systems to study host-pathogen interactions.

Dutta D, Clevers H.

Curr Opin Immunol. 2017 Oct;48:15-22. doi: 10.1016/j.coi.2017.07.012. Epub 2017 Aug 9. Review.

PMID:
28756233
38.

MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.

Joosten SPJ, Zeilstra J, van Andel H, Mijnals RC, Zaunbrecher J, Duivenvoorden AAM, van de Wetering M, Clevers H, Spaargaren M, Pals ST.

Gastroenterology. 2017 Oct;153(4):1040-1053.e4. doi: 10.1053/j.gastro.2017.07.008. Epub 2017 Jul 14.

PMID:
28716720
39.

Origins of lymphatic and distant metastases in human colorectal cancer.

Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK.

Science. 2017 Jul 7;357(6346):55-60. doi: 10.1126/science.aai8515.

40.

How the Gut Feels, Smells, and Talks.

Beumer J, Clevers H.

Cell. 2017 Jun 29;170(1):10-11. doi: 10.1016/j.cell.2017.06.023.

41.

Stem Cells in Repair of Gastrointestinal Epithelia.

Andersson-Rolf A, Zilbauer M, Koo BK, Clevers H.

Physiology (Bethesda). 2017 Jul;32(4):278-289. doi: 10.1152/physiol.00005.2017. Review.

42.

Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo.

Flanagan DJ, Barker N, Nowell C, Clevers H, Ernst M, Phesse TJ, Vincan E.

Dis Model Mech. 2017 Aug 1;10(8):971-980. doi: 10.1242/dmm.029876. Epub 2017 Jun 9.

43.

Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities.

Nusse R, Clevers H.

Cell. 2017 Jun 1;169(6):985-999. doi: 10.1016/j.cell.2017.05.016. Review.

44.

Wnt/β-catenin signaling in adult mammalian epithelial stem cells.

Kretzschmar K, Clevers H.

Dev Biol. 2017 Aug 15;428(2):273-282. doi: 10.1016/j.ydbio.2017.05.015. Epub 2017 May 17. Review.

45.

Lineage-dependent spatial and functional organization of the mammalian enteric nervous system.

Lasrado R, Boesmans W, Kleinjung J, Pin C, Bell D, Bhaw L, McCallum S, Zong H, Luo L, Clevers H, Vanden Berghe P, Pachnis V.

Science. 2017 May 19;356(6339):722-726. doi: 10.1126/science.aam7511.

PMID:
28522527
46.

Oncogene-inducible organoids as a miniature platform to assess cancer characteristics.

Mizutani T, Tsukamoto Y, Clevers H.

J Cell Biol. 2017 Jun 5;216(6):1505-1507. doi: 10.1083/jcb.201704014. Epub 2017 May 16.

47.

SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells.

Morcos MNF, Schoedel KB, Hoppe A, Behrendt R, Basak O, Clevers HC, Roers A, Gerbaulet A.

Stem Cell Reports. 2017 Jun 6;8(6):1472-1478. doi: 10.1016/j.stemcr.2017.04.012. Epub 2017 May 11.

48.

Goblet Cells Contribute to Ocular Surface Immune Tolerance-Implications for Dry Eye Disease.

Barbosa FL, Xiao Y, Bian F, Coursey TG, Ko BY, Clevers H, de Paiva CS, Pflugfelder SC.

Int J Mol Sci. 2017 May 5;18(5). pii: E978. doi: 10.3390/ijms18050978.

49.

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.

Janda CY, Dang LT, You C, Chang J, de Lau W, Zhong ZA, Yan KS, Marecic O, Siepe D, Li X, Moody JD, Williams BO, Clevers H, Piehler J, Baker D, Kuo CJ, Garcia KC.

Nature. 2017 May 11;545(7653):234-237. doi: 10.1038/nature22306. Epub 2017 May 3.

50.

Beyond growth signaling: Paneth cells metabolically support ISCs.

Dayton TL, Clevers H.

Cell Res. 2017 Jul;27(7):851-852. doi: 10.1038/cr.2017.59. Epub 2017 Apr 21.

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