Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 645

1.

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer.

Whittle JR, Vaillant F, Surgenor E, Policheni AN, Giner G, Capaldo BD, Chen HR, Liu HK, Dekkers JF, Sachs N, Clevers H, Fellowes A, Green T, Xu H, Fox SB, Herold MJ, Smyth GK, Gray DHD, Visvader JE, Lindeman GJ.

Clin Cancer Res. 2020 Apr 3. pii: clincanres.1872.2019. doi: 10.1158/1078-0432.CCR-19-1872. [Epub ahead of print]

PMID:
32245900
2.

Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.

Yan HHN, Siu HC, Ho SL, Yue SSK, Gao Y, Tsui WY, Chan D, Chan AS, Wong JWH, Man AHY, Lee BCH, Chan ASY, Chan AKW, Hui HS, Cheung AKL, Law WL, Lo OSH, Yuen ST, Clevers H, Leung SY.

Gut. 2020 Mar 26. pii: gutjnl-2019-320019. doi: 10.1136/gutjnl-2019-320019. [Epub ahead of print]

PMID:
32217638
3.

Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors.

Wang D, Wang J, Bai L, Pan H, Feng H, Clevers H, Zeng YA.

Cell. 2020 Mar 19;180(6):1198-1211.e19. doi: 10.1016/j.cell.2020.02.048.

PMID:
32200801
4.

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity.

Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, Ammerlaan C, van Ineveld RL, Derakhshan S, de Haan S, Dolman E, Lijnzaad P, Custers L, Begthel H, Kerstens HHD, Visser LL, Rookmaaker M, Verhaar M, Tytgat GAM, Kemmeren P, de Krijger RR, Al-Saadi R, Pritchard-Jones K, Kool M, Rios AC, van den Heuvel-Eibrink MM, Molenaar JJ, van Boxtel R, Holstege FCP, Clevers H, Drost J.

Nat Commun. 2020 Mar 11;11(1):1310. doi: 10.1038/s41467-020-15155-6.

5.

Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance.

Ringel T, Frey N, Ringnalda F, Janjuha S, Cherkaoui S, Butz S, Srivatsa S, Pirkl M, Russo G, Villiger L, Rogler G, Clevers H, Beerenwinkel N, Zamboni N, Baubec T, Schwank G.

Cell Stem Cell. 2020 Mar 5;26(3):431-440.e8. doi: 10.1016/j.stem.2020.02.007.

PMID:
32142663
6.

Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies.

Battich N, Beumer J, de Barbanson B, Krenning L, Baron CS, Tanenbaum ME, Clevers H, van Oudenaarden A.

Science. 2020 Mar 6;367(6482):1151-1156. doi: 10.1126/science.aax3072.

PMID:
32139547
7.

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing.

Artegiani B, Hendriks D, Beumer J, Kok R, Zheng X, Joore I, Chuva de Sousa Lopes S, van Zon J, Tans S, Clevers H.

Nat Cell Biol. 2020 Mar;22(3):321-331. doi: 10.1038/s41556-020-0472-5. Epub 2020 Mar 2.

PMID:
32123335
8.

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli.

Pleguezuelos-Manzano C, Puschhof J, Huber AR, van Hoeck A, Wood HM, Nomburg J, Gurjao C, Manders F, Dalmasso G, Stege PB, Paganelli FL, Geurts MH, Beumer J, Mizutani T, Miao Y, van der Linden R, van Elst S; Genomics England Research Consortium, Garcia KC, Top J, Willems RJL, Giannakis M, Bonnet R, Quirke P, Meyerson M, Cuppen E, van Boxtel R, Clevers H.

Nature. 2020 Feb 27. doi: 10.1038/s41586-020-2080-8. [Epub ahead of print]

PMID:
32106218
9.

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids.

Wiechmann S, Maisonneuve P, Grebbin BM, Hoffmeister M, Kaulich M, Clevers H, Rajalingam K, Kurinov I, Farin HF, Sicheri F, Ernst A.

J Biol Chem. 2020 Apr 3;295(14):4526-4540. doi: 10.1074/jbc.RA119.011025. Epub 2020 Feb 20.

PMID:
32086379
10.

Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells.

Murata K, Jadhav U, Madha S, van Es J, Dean J, Cavazza A, Wucherpfennig K, Michor F, Clevers H, Shivdasani RA.

Cell Stem Cell. 2020 Mar 5;26(3):377-390.e6. doi: 10.1016/j.stem.2019.12.011. Epub 2020 Feb 20.

PMID:
32084390
11.

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank.

Geurts MH, de Poel E, Amatngalim GD, Oka R, Meijers FM, Kruisselbrink E, van Mourik P, Berkers G, de Winter-de Groot KM, Michel S, Muilwijk D, Aalbers BL, Mullenders J, Boj SF, Suen SWF, Brunsveld JE, Janssens HM, Mall MA, Graeber SY, van Boxtel R, van der Ent CK, Beekman JM, Clevers H.

Cell Stem Cell. 2020 Apr 2;26(4):503-510.e7. doi: 10.1016/j.stem.2020.01.019. Epub 2020 Feb 20.

PMID:
32084388
12.

Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease.

Kruitwagen HS, Oosterhoff LA, van Wolferen ME, Chen C, Nantasanti Assawarachan S, Schneeberger K, Kummeling A, van Straten G, Akkerdaas IC, Vinke CR, van Steenbeek FG, van Bruggen LWL, Wolfswinkel J, Grinwis GCM, Fuchs SA, Gehart H, Geijsen N, Vries RG, Clevers H, Rothuizen J, Schotanus BA, Penning LC, Spee B.

Cells. 2020 Feb 11;9(2). pii: E410. doi: 10.3390/cells9020410.

13.

Snake Venom Gland Organoids.

Post Y, Puschhof J, Beumer J, Kerkkamp HM, de Bakker MAG, Slagboom J, de Barbanson B, Wevers NR, Spijkers XM, Olivier T, Kazandjian TD, Ainsworth S, Iglesias CL, van de Wetering WJ, Heinz MC, van Ineveld RL, van Kleef RGDM, Begthel H, Korving J, Bar-Ephraim YE, Getreuer W, Rios AC, Westerink RHS, Snippert HJG, van Oudenaarden A, Peters PJ, Vonk FJ, Kool J, Richardson MK, Casewell NR, Clevers H.

Cell. 2020 Jan 23;180(2):233-247.e21. doi: 10.1016/j.cell.2019.11.038.

PMID:
31978343
14.

LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.

Gao Y, Yan Y, Tripathi S, Pentinmikko N, Amaral A, Päivinen P, Domènech-Moreno E, Andersson S, Wong IPL, Clevers H, Katajisto P, Mäkelä TP.

Gastroenterology. 2020 Apr;158(5):1389-1401.e10. doi: 10.1053/j.gastro.2019.12.033. Epub 2020 Jan 11.

PMID:
31930988
15.

Organoids: Avatars for Personalized Medicine.

Clevers HC.

Keio J Med. 2019;68(4):95. doi: 10.2302/kjm.68-006-ABST.

16.

Organoids in immunological research.

Bar-Ephraim YE, Kretzschmar K, Clevers H.

Nat Rev Immunol. 2019 Dec 18. doi: 10.1038/s41577-019-0248-y. [Epub ahead of print] Review.

PMID:
31853049
17.

Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion.

van Es JH, Wiebrands K, López-Iglesias C, van de Wetering M, Zeinstra L, van den Born M, Korving J, Sasaki N, Peters PJ, van Oudenaarden A, Clevers H.

Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 201801888. doi: 10.1073/pnas.1801888117. [Epub ahead of print]

PMID:
31843916
18.

Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies.

Ouahed J, Spencer E, Kotlarz D, Shouval DS, Kowalik M, Peng K, Field M, Grushkin-Lerner L, Pai SY, Bousvaros A, Cho J, Argmann C, Schadt E, Mcgovern DPB, Mokry M, Nieuwenhuis E, Clevers H, Powrie F, Uhlig H, Klein C, Muise A, Dubinsky M, Snapper SB.

Inflamm Bowel Dis. 2019 Dec 3. pii: izz259. doi: 10.1093/ibd/izz259. [Epub ahead of print]

PMID:
31833544
19.

Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture.

Giobbe GG, Crowley C, Luni C, Campinoti S, Khedr M, Kretzschmar K, De Santis MM, Zambaiti E, Michielin F, Meran L, Hu Q, van Son G, Urbani L, Manfredi A, Giomo M, Eaton S, Cacchiarelli D, Li VSW, Clevers H, Bonfanti P, Elvassore N, De Coppi P.

Nat Commun. 2019 Dec 11;10(1):5658. doi: 10.1038/s41467-019-13605-4.

20.

Pancreatic cancer organoids recapitulate disease and allow personalized drug screening.

Driehuis E, van Hoeck A, Moore K, Kolders S, Francies HE, Gulersonmez MC, Stigter ECA, Burgering B, Geurts V, Gracanin A, Bounova G, Morsink FH, Vries R, Boj S, van Es J, Offerhaus GJA, Kranenburg O, Garnett MJ, Wessels L, Cuppen E, Brosens LAA, Clevers H.

Proc Natl Acad Sci U S A. 2019 Dec 9. pii: 201911273. doi: 10.1073/pnas.1911273116. [Epub ahead of print]

PMID:
31818951
21.

IFN-γ: The T cell's license to kill stem cells in the inflamed intestine.

Kretzschmar K, Clevers H.

Sci Immunol. 2019 Dec 6;4(42). pii: eaaz6821. doi: 10.1126/sciimmunol.aaz6821. Review.

PMID:
31811056
22.

Patient-Derived Organoids Predict Chemoradiation Responses of Locally Advanced Rectal Cancer.

Yao Y, Xu X, Yang L, Zhu J, Wan J, Shen L, Xia F, Fu G, Deng Y, Pan M, Guo Q, Gao X, Li Y, Rao X, Zhou Y, Liang L, Wang Y, Zhang J, Zhang H, Li G, Zhang L, Peng J, Cai S, Hu C, Gao J, Clevers H, Zhang Z, Hua G.

Cell Stem Cell. 2020 Jan 2;26(1):17-26.e6. doi: 10.1016/j.stem.2019.10.010. Epub 2019 Nov 21.

PMID:
31761724
23.

Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations.

de Winter-de Groot KM, Berkers G, Marck-van der Wilt REP, van der Meer R, Vonk A, Dekkers JF, Geerdink M, Michel S, Kruisselbrink E, Vries R, Clevers H, Vleggaar FP, Elias SG, Heijerman HGM, van der Ent CK, Beekman JM.

J Cyst Fibros. 2019 Nov 14. pii: S1569-1993(19)30937-3. doi: 10.1016/j.jcf.2019.10.022. [Epub ahead of print]

PMID:
31735562
24.

Large-scale Production of LGR5-positive Bipotential Human Liver Stem Cells.

Schneeberger K, Sánchez-Romero N, Ye S, van Steenbeek FG, Oosterhoff LA, Pla Palacin I, Chen C, van Wolferen ME, van Tienderen G, Lieshout R, Colemonts-Vroninks H, Schene I, Hoekstra R, Verstegen MMA, van der Laan LJW, Penning LC, Fuchs SA, Clevers H, De Kock J, Baptista PM, Spee B.

Hepatology. 2019 Nov 12. doi: 10.1002/hep.31037. [Epub ahead of print]

PMID:
31715015
25.

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy.

Driehuis E, Spelier S, Beltrán Hernández I, de Bree R, M Willems S, Clevers H, Oliveira S.

J Clin Med. 2019 Nov 5;8(11). pii: E1880. doi: 10.3390/jcm8111880.

26.

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.

Ooft SN, Weeber F, Dijkstra KK, McLean CM, Kaing S, van Werkhoven E, Schipper L, Hoes L, Vis DJ, van de Haar J, Prevoo W, Snaebjornsson P, van der Velden D, Klein M, Chalabi M, Boot H, van Leerdam M, Bloemendal HJ, Beerepoot LV, Wessels L, Cuppen E, Clevers H, Voest EE.

Sci Transl Med. 2019 Oct 9;11(513). pii: eaay2574. doi: 10.1126/scitranslmed.aay2574.

PMID:
31597751
27.

A rectal cancer organoid platform to study individual responses to chemoradiation.

Ganesh K, Wu C, O'Rourke KP, Szeglin BC, Zheng Y, Sauvé CG, Adileh M, Wasserman I, Marco MR, Kim AS, Shady M, Sanchez-Vega F, Karthaus WR, Won HH, Choi SH, Pelossof R, Barlas A, Ntiamoah P, Pappou E, Elghouayel A, Strong JS, Chen CT, Harris JW, Weiser MR, Nash GM, Guillem JG, Wei IH, Kolesnick RN, Veeraraghavan H, Ortiz EJ, Petkovska I, Cercek A, Manova-Todorova KO, Saltz LB, Lavery JA, DeMatteo RP, Massagué J, Paty PB, Yaeger R, Chen X, Patil S, Clevers H, Berger MF, Lowe SW, Shia J, Romesser PB, Dow LE, Garcia-Aguilar J, Sawyers CL, Smith JJ.

Nat Med. 2019 Oct;25(10):1607-1614. doi: 10.1038/s41591-019-0584-2. Epub 2019 Oct 7.

PMID:
31591597
28.

Modeling breast cancer using CRISPR/Cas9-mediated engineering of human breast organoids.

Dekkers JF, Whittle JR, Vaillant F, Chen HR, Dawson C, Liu K, Geurts M, Herold MJ, Clevers H, Lindeman GJ, Visvader JE.

J Natl Cancer Inst. 2019 Oct 7. pii: djz196. doi: 10.1093/jnci/djz196. [Epub ahead of print]

PMID:
31589320
29.

Human Organoids: Tools for Understanding Biology and Treating Diseases.

Schutgens F, Clevers H.

Annu Rev Pathol. 2020 Jan 24;15:211-234. doi: 10.1146/annurev-pathmechdis-012419-032611. Epub 2019 Sep 24.

PMID:
31550983
30.

Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.

Han S, Fink J, Jörg DJ, Lee E, Yum MK, Chatzeli L, Merker SR, Josserand M, Trendafilova T, Andersson-Rolf A, Dabrowska C, Kim H, Naumann R, Lee JH, Sasaki N, Mort RL, Basak O, Clevers H, Stange DE, Philpott A, Kim JK, Simons BD, Koo BK.

Cell Stem Cell. 2019 Sep 5;25(3):342-356.e7. doi: 10.1016/j.stem.2019.07.008. Epub 2019 Aug 15.

31.

A Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues.

Klotz BJ, Oosterhoff LA, Utomo L, Lim KS, Vallmajo-Martin Q, Clevers H, Woodfield TBF, Rosenberg AJWP, Malda J, Ehrbar M, Spee B, Gawlitta D.

Adv Healthc Mater. 2019 Oct;8(19):e1900979. doi: 10.1002/adhm.201900979. Epub 2019 Aug 12.

PMID:
31402634
32.

Defining Adult Stem Cell Function at Its Simplest: The Ability to Replace Lost Cells through Mitosis.

Post Y, Clevers H.

Cell Stem Cell. 2019 Aug 1;25(2):174-183. doi: 10.1016/j.stem.2019.07.002. Review.

PMID:
31374197
33.

Xenograft and organoid model systems in cancer research.

Bleijs M, van de Wetering M, Clevers H, Drost J.

EMBO J. 2019 Aug 1;38(15):e101654. doi: 10.15252/embj.2019101654. Epub 2019 Jul 8. Review.

34.

T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation.

Fu YY, Egorova A, Sobieski C, Kuttiyara J, Calafiore M, Takashima S, Clevers H, Hanash AM.

Immunity. 2019 Jul 16;51(1):90-103.e3. doi: 10.1016/j.immuni.2019.06.003. Epub 2019 Jul 2.

PMID:
31278057
35.

MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance.

Joosten SPJ, Mizutani T, Spaargaren M, Clevers H, Pals ST.

Gastroenterology. 2019 Oct;157(4):1153-1155.e1. doi: 10.1053/j.gastro.2019.06.029. Epub 2019 Jun 27. No abstract available.

PMID:
31255653
36.

Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.

Boonekamp KE, Kretzschmar K, Wiener DJ, Asra P, Derakhshan S, Puschhof J, López-Iglesias C, Peters PJ, Basak O, Clevers H.

Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14630-14638. doi: 10.1073/pnas.1715272116. Epub 2019 Jun 28.

37.

Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.

Wang H, Xiang D, Liu B, He A, Randle HJ, Zhang KX, Dongre A, Sachs N, Clark AP, Tao L, Chen Q, Botchkarev VV Jr, Xie Y, Dai N, Clevers H, Li Z, Livingston DM.

Cell. 2019 Jun 27;178(1):135-151.e19. doi: 10.1016/j.cell.2019.06.002.

PMID:
31251913
38.

Tissue-Engineering the Intestine: The Trials before the Trials.

Clevers H, Conder RK, Li VSW, Lutolf MP, Vallier L, Chan S, Grikscheit TC, Jensen KB, De Coppi P.

Cell Stem Cell. 2019 Jun 6;24(6):855-859. doi: 10.1016/j.stem.2019.04.018.

PMID:
31173715
39.

Cancer modeling meets human organoid technology.

Tuveson D, Clevers H.

Science. 2019 Jun 7;364(6444):952-955. doi: 10.1126/science.aaw6985.

PMID:
31171691
40.

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.

Artegiani B, van Voorthuijsen L, Lindeboom RGH, Seinstra D, Heo I, Tapia P, López-Iglesias C, Postrach D, Dayton T, Oka R, Hu H, van Boxtel R, van Es JH, Offerhaus J, Peters PJ, van Rheenen J, Vermeulen M, Clevers H.

Cell Stem Cell. 2019 Jun 6;24(6):927-943.e6. doi: 10.1016/j.stem.2019.04.017. Epub 2019 May 23.

PMID:
31130514
41.

High-resolution 3D imaging of fixed and cleared organoids.

Dekkers JF, Alieva M, Wellens LM, Ariese HCR, Jamieson PR, Vonk AM, Amatngalim GD, Hu H, Oost KC, Snippert HJG, Beekman JM, Wehrens EJ, Visvader JE, Clevers H, Rios AC.

Nat Protoc. 2019 Jun;14(6):1756-1771. doi: 10.1038/s41596-019-0160-8. Epub 2019 May 3.

PMID:
31053799
42.

Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy.

Driehuis E, Kolders S, Spelier S, Lõhmussaar K, Willems SM, Devriese LA, de Bree R, de Ruiter EJ, Korving J, Begthel H, van Es JH, Geurts V, He GW, van Jaarsveld RH, Oka R, Muraro MJ, Vivié J, Zandvliet MMJM, Hendrickx APA, Iakobachvili N, Sridevi P, Kranenburg O, van Boxtel R, Kops GJPL, Tuveson DA, Peters PJ, van Oudenaarden A, Clevers H.

Cancer Discov. 2019 Jul;9(7):852-871. doi: 10.1158/2159-8290.CD-18-1522. Epub 2019 May 3. Erratum in: Cancer Discov. 2020 Mar;10(3):476.

PMID:
31053628
43.

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids.

Bolhaqueiro ACF, Ponsioen B, Bakker B, Klaasen SJ, Kucukkose E, van Jaarsveld RH, Vivié J, Verlaan-Klink I, Hami N, Spierings DCJ, Sasaki N, Dutta D, Boj SF, Vries RGJ, Lansdorp PM, van de Wetering M, van Oudenaarden A, Clevers H, Kranenburg O, Foijer F, Snippert HJG, Kops GJPL.

Nat Genet. 2019 May;51(5):824-834. doi: 10.1038/s41588-019-0399-6. Epub 2019 Apr 29.

PMID:
31036964
44.

Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time.

Crosby P, Hamnett R, Putker M, Hoyle NP, Reed M, Karam CJ, Maywood ES, Stangherlin A, Chesham JE, Hayter EA, Rosenbrier-Ribeiro L, Newham P, Clevers H, Bechtold DA, O'Neill JS.

Cell. 2019 May 2;177(4):896-909.e20. doi: 10.1016/j.cell.2019.02.017. Epub 2019 Apr 25.

45.

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity.

Kopper O, de Witte CJ, Lõhmussaar K, Valle-Inclan JE, Hami N, Kester L, Balgobind AV, Korving J, Proost N, Begthel H, van Wijk LM, Revilla SA, Theeuwsen R, van de Ven M, van Roosmalen MJ, Ponsioen B, Ho VWH, Neel BG, Bosse T, Gaarenstroom KN, Vrieling H, Vreeswijk MPG, van Diest PJ, Witteveen PO, Jonges T, Bos JL, van Oudenaarden A, Zweemer RP, Snippert HJG, Kloosterman WP, Clevers H.

Nat Med. 2019 May;25(5):838-849. doi: 10.1038/s41591-019-0422-6. Epub 2019 Apr 22.

PMID:
31011202
46.

Tubuloids derived from human adult kidney and urine for personalized disease modeling.

Schutgens F, Rookmaaker MB, Margaritis T, Rios A, Ammerlaan C, Jansen J, Gijzen L, Vormann M, Vonk A, Viveen M, Yengej FY, Derakhshan S, de Winter-de Groot KM, Artegiani B, van Boxtel R, Cuppen E, Hendrickx APA, van den Heuvel-Eibrink MM, Heitzer E, Lanz H, Beekman J, Murk JL, Masereeuw R, Holstege F, Drost J, Verhaar MC, Clevers H.

Nat Biotechnol. 2019 Mar;37(3):303-313. doi: 10.1038/s41587-019-0048-8. Epub 2019 Mar 4.

PMID:
30833775
47.

Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors.

Cabeza-Cabrerizo M, van Blijswijk J, Wienert S, Heim D, Jenkins RP, Chakravarty P, Rogers N, Frederico B, Acton S, Beerling E, van Rheenen J, Clevers H, Schraml BU, Bajénoff M, Gerner M, Germain RN, Sahai E, Klauschen F, Reis E Sousa C.

Sci Immunol. 2019 Mar 1;4(33). pii: eaaw1941. doi: 10.1126/sciimmunol.aaw1941.

48.

Mouse and human urothelial cancer organoids: A tool for bladder cancer research.

Mullenders J, de Jongh E, Brousali A, Roosen M, Blom JPA, Begthel H, Korving J, Jonges T, Kranenburg O, Meijer R, Clevers HC.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4567-4574. doi: 10.1073/pnas.1803595116. Epub 2019 Feb 20.

49.

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

Li N, Babaei-Jadidi R, Lorenzi F, Spencer-Dene B, Clarke P, Domingo E, Tulchinsky E, Vries RGJ, Kerr D, Pan Y, He Y, Bates DO, Tomlinson I, Clevers H, Nateri AS.

Oncogenesis. 2019 Feb 19;8(3):13. doi: 10.1038/s41389-019-0125-3.

50.

Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses.

Fakhiri J, Schneider MA, Puschhof J, Stanifer M, Schildgen V, Holderbach S, Voss Y, El Andari J, Schildgen O, Boulant S, Meister M, Clevers H, Yan Z, Qiu J, Grimm D.

Mol Ther Methods Clin Dev. 2019 Jan 18;12:202-222. doi: 10.1016/j.omtm.2019.01.003. eCollection 2019 Mar 15.

Supplemental Content

Loading ...
Support Center