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Items: 46

1.

PM2.5 induces vascular permeability increase through activating MAPK/ERK signaling pathway and ROS generation.

Long YM, Yang XZ, Yang QQ, Clermont AC, Yin YG, Liu GL, Hu LG, Liu Q, Zhou QF, Liu QS, Ma QC, Liu YC, Cai Y.

J Hazard Mater. 2019 Nov 10:121659. doi: 10.1016/j.jhazmat.2019.121659. [Epub ahead of print]

PMID:
31776080
2.

Retinal proteome associated with bradykinin-induced edema.

Murugesan N, Fickweiler W, Clermont AC, Zhou Q, Feener EP.

Exp Eye Res. 2019 Sep;186:107744. doi: 10.1016/j.exer.2019.107744. Epub 2019 Jul 24.

PMID:
31351056
3.

Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy.

Yokomizo H, Maeda Y, Park K, Clermont AC, Hernandez SL, Fickweiler W, Li Q, Wang CH, Paniagua SM, Simao F, Ishikado A, Sun B, Wu IH, Katagiri S, Pober DM, Tinsley LJ, Avery RL, Feener EP, Kern TS, Keenan HA, Aiello LP, Sun JK, King GL.

Sci Transl Med. 2019 Jul 3;11(499). pii: eaau6627. doi: 10.1126/scitranslmed.aau6627.

PMID:
31270273
4.

Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase.

Solheim MH, Clermont AC, Winnay JN, Hallstensen E, Molven A, Njølstad PR, Rødahl E, Kahn CR.

Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):3100-3106. doi: 10.1167/iovs.16-21347.

5.

Plasma kallikrein mediates brain hemorrhage and edema caused by tissue plasminogen activator therapy in mice after stroke.

Simão F, Ustunkaya T, Clermont AC, Feener EP.

Blood. 2017 Apr 20;129(16):2280-2290. doi: 10.1182/blood-2016-09-740670. Epub 2017 Jan 27.

6.

Evaluating anesthetic protocols for functional blood flow imaging in the rat eye.

Moult EM, Choi W, Boas DA, Baumann B, Clermont AC, Feener EP, Fujimoto JG.

J Biomed Opt. 2017 Jan 1;22(1):16005. doi: 10.1117/1.JBO.22.1.016005.

7.

Negatively charged silver nanoparticles cause retinal vascular permeability by activating plasma contact system and disrupting adherens junction.

Long YM, Zhao XC, Clermont AC, Zhou QF, Liu Q, Feener EP, Yan B, Jiang GB.

Nanotoxicology. 2016;10(4):501-11. doi: 10.3109/17435390.2015.1088589. Epub 2015 Sep 23.

8.

Plasma Kallikrein-Kinin System as a VEGF-Independent Mediator of Diabetic Macular Edema.

Kita T, Clermont AC, Murugesan N, Zhou Q, Fujisawa K, Ishibashi T, Aiello LP, Feener EP.

Diabetes. 2015 Oct;64(10):3588-99. doi: 10.2337/db15-0317. Epub 2015 May 15.

9.

Modeling targeted inhibition of MEK and PI3 kinase in human pancreatic cancer.

Junttila MR, Devasthali V, Cheng JH, Castillo J, Metcalfe C, Clermont AC, Otter DD, Chan E, Bou-Reslan H, Cao T, Forrest W, Nannini MA, French D, Carano R, Merchant M, Hoeflich KP, Singh M.

Mol Cancer Ther. 2015 Jan;14(1):40-7. doi: 10.1158/1535-7163.MCT-14-0030. Epub 2014 Nov 5.

10.

Identification and analysis of in vivo VEGF downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies.

Brauer MJ, Zhuang G, Schmidt M, Yao J, Wu X, Kaminker JS, Jurinka SS, Kolumam G, Chung AS, Jubb A, Modrusan Z, Ozawa T, James CD, Phillips H, Haley B, Tam RN, Clermont AC, Cheng JH, Yang SX, Swain SM, Chen D, Scherer SJ, Koeppen H, Yeh RF, Yue P, Stephan JP, Hegde P, Ferrara N, Singh M, Bais C.

Clin Cancer Res. 2013 Jul 1;19(13):3681-92. doi: 10.1158/1078-0432.CCR-12-3635. Epub 2013 May 17.

11.

Intraocular hemorrhage causes retinal vascular dysfunction via plasma kallikrein.

Liu J, Clermont AC, Gao BB, Feener EP.

Invest Ophthalmol Vis Sci. 2013 Feb 7;54(2):1086-94. doi: 10.1167/iovs.12-10537.

12.

Measurement of pulsatile total blood flow in the human and rat retina with ultrahigh speed spectral/Fourier domain OCT.

Choi W, Baumann B, Liu JJ, Clermont AC, Feener EP, Duker JS, Fujimoto JG.

Biomed Opt Express. 2012 May 1;3(5):1047-61. doi: 10.1364/BOE.3.001047. Epub 2012 Apr 19.

13.

Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice.

Rask-Madsen C, Buonomo E, Li Q, Park K, Clermont AC, Yerokun O, Rekhter M, King GL.

Arterioscler Thromb Vasc Biol. 2012 May;32(5):1124-31. doi: 10.1161/ATVBAHA.111.239558. Epub 2012 Mar 15.

14.

Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein.

Liu J, Gao BB, Clermont AC, Blair P, Chilcote TJ, Sinha S, Flaumenhaft R, Feener EP.

Nat Med. 2011 Feb;17(2):206-10. doi: 10.1038/nm.2295. Epub 2011 Jan 23.

15.

Vitreous proteomics and diabetic retinopathy.

Walia S, Clermont AC, Gao BB, Aiello LP, Feener EP.

Semin Ophthalmol. 2010 Sep-Nov;25(5-6):289-94. doi: 10.3109/08820538.2010.518912. Review.

16.

Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models.

Singh M, Lima A, Molina R, Hamilton P, Clermont AC, Devasthali V, Thompson JD, Cheng JH, Bou Reslan H, Ho CC, Cao TC, Lee CV, Nannini MA, Fuh G, Carano RA, Koeppen H, Yu RX, Forrest WF, Plowman GD, Johnson L.

Nat Biotechnol. 2010 Jun;28(6):585-93. doi: 10.1038/nbt.1640. Epub 2010 May 23.

PMID:
20495549
17.

Angiotensin AT1 receptor antagonism ameliorates murine retinal proteome changes induced by diabetes.

Gao BB, Phipps JA, Bursell D, Clermont AC, Feener EP.

J Proteome Res. 2009 Dec;8(12):5541-9. doi: 10.1021/pr9006415.

18.

Plasma kallikrein mediates angiotensin II type 1 receptor-stimulated retinal vascular permeability.

Phipps JA, Clermont AC, Sinha S, Chilcote TJ, Bursell SE, Feener EP.

Hypertension. 2009 Feb;53(2):175-81. doi: 10.1161/HYPERTENSIONAHA.108.117663. Epub 2009 Jan 5.

19.

Studies with an orally bioavailable alpha V integrin antagonist in animal models of ocular vasculopathy: retinal neovascularization in mice and retinal vascular permeability in diabetic rats.

Santulli RJ, Kinney WA, Ghosh S, Decorte BL, Liu L, Tuman RW, Zhou Z, Huebert N, Bursell SE, Clermont AC, Grant MB, Shaw LC, Mousa SA, Galemmo RA Jr, Johnson DL, Maryanoff BE, Damiano BP.

J Pharmacol Exp Ther. 2008 Mar;324(3):894-901. Epub 2007 Dec 14.

PMID:
18083913
20.

Retinal blood flow in diabetes.

Clermont AC, Bursell SE.

Microcirculation. 2007 Jan;14(1):49-61. Review.

PMID:
17365661
21.

Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice.

Ohshiro Y, Ma RC, Yasuda Y, Hiraoka-Yamamoto J, Clermont AC, Isshiki K, Yagi K, Arikawa E, Kern TS, King GL.

Diabetes. 2006 Nov;55(11):3112-20.

22.

Hepatocyte growth factor induces retinal vascular permeability via MAP-kinase and PI-3 kinase without altering retinal hemodynamics.

Clermont AC, Cahill M, Salti H, Rook SL, Rask-Madsen C, Goddard L, Wong JS, Bursell D, Bursell SE, Aiello LP.

Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2701-8.

PMID:
16723489
23.

Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance.

Naruse K, Rask-Madsen C, Takahara N, Ha SW, Suzuma K, Way KJ, Jacobs JR, Clermont AC, Ueki K, Ohshiro Y, Zhang J, Goldfine AB, King GL.

Diabetes. 2006 Mar;55(3):691-8.

24.

Angiotensin AT(1) receptor antagonism normalizes retinal blood flow and acetylcholine-induced vasodilatation in normotensive diabetic rats.

Horio N, Clermont AC, Abiko A, Abiko T, Shoelson BD, Bursell SE, Feener EP.

Diabetologia. 2004 Jan;47(1):113-23. Epub 2003 Nov 14.

PMID:
14618237
25.

Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation.

Abiko T, Abiko A, Clermont AC, Shoelson B, Horio N, Takahashi J, Adamis AP, King GL, Bursell SE.

Diabetes. 2003 Mar;52(3):829-37.

26.

Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue.

Chou E, Suzuma I, Way KJ, Opland D, Clermont AC, Naruse K, Suzuma K, Bowling NL, Vlahos CJ, Aiello LP, King GL.

Circulation. 2002 Jan 22;105(3):373-9.

PMID:
11804995
27.

Stereo nonmydriatic digital-video color retinal imaging compared with Early Treatment Diabetic Retinopathy Study seven standard field 35-mm stereo color photos for determining level of diabetic retinopathy.

Bursell SE, Cavallerano JD, Cavallerano AA, Clermont AC, Birkmire-Peters D, Aiello LP, Aiello LM; Joslin Vision Network Research Team.

Ophthalmology. 2001 Mar;108(3):572-85.

PMID:
11237913
28.

von Willebrand factor and retinal circulation in early-stage retinopathy of type 1 diabetes.

Feng D, Bursell SE, Clermont AC, Lipinska I, Aiello LP, Laffel L, King GL, Tofler GH.

Diabetes Care. 2000 Nov;23(11):1694-8.

29.

Endothelin-3 regulation of retinal hemodynamics in nondiabetic and diabetic rats.

Mori F, King GL, Clermont AC, Bursell DK, Bursell SE.

Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3955-62.

PMID:
11053299
30.

Role of the angiotensin AT(1) receptor in rat aortic and cardiac PAI-1 gene expression.

Chen HC, Bouchie JL, Perez AS, Clermont AC, Izumo S, Hampe J, Feener EP.

Arterioscler Thromb Vasc Biol. 2000 Oct;20(10):2297-302.

PMID:
11031218
31.

Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition.

Miyamoto K, Khosrof S, Bursell SE, Rohan R, Murata T, Clermont AC, Aiello LP, Ogura Y, Adamis AP.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10836-41.

32.

High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes.

Bursell SE, Clermont AC, Aiello LP, Aiello LM, Schlossman DK, Feener EP, Laffel L, King GL.

Diabetes Care. 1999 Aug;22(8):1245-51.

33.

Reversibility of retinal flow abnormalities is disease-duration dependent in diabetic rats.

Higashi S, Clermont AC, Dhir V, Bursell SE.

Diabetes. 1998 Apr;47(4):653-9.

PMID:
9568700
34.

Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats.

Bursell SE, Takagi C, Clermont AC, Takagi H, Mori F, Ishii H, King GL.

Invest Ophthalmol Vis Sci. 1997 Dec;38(13):2711-20.

PMID:
9418723
36.

Regulation of retinal hemodynamics in diabetic rats by increased expression and action of endothelin-1.

Takagi C, Bursell SE, Lin YW, Takagi H, Duh E, Jiang Z, Clermont AC, King GL.

Invest Ophthalmol Vis Sci. 1996 Nov;37(12):2504-18.

PMID:
8933767
37.

Endothelin-1 action via endothelin receptors is a primary mechanism modulating retinal circulatory response to hyperoxia.

Takagi C, King GL, Takagi H, Lin YW, Clermont AC, Bursell SE.

Invest Ophthalmol Vis Sci. 1996 Sep;37(10):2099-109.

PMID:
8814149
38.

Retinal blood flow changes in patients with insulin-dependent diabetes mellitus and no diabetic retinopathy.

Bursell SE, Clermont AC, Kinsley BT, Simonson DC, Aiello LM, Wolpert HA.

Invest Ophthalmol Vis Sci. 1996 Apr;37(5):886-97.

PMID:
8603873
39.

Reversal of abnormal retinal hemodynamics in diabetic rats by acarbose, an alpha-glucosidase inhibitor.

Takagi C, King GL, Clermont AC, Cummins DR, Takagi H, Bursell SE.

Curr Eye Res. 1995 Sep;14(9):741-9.

PMID:
8529412
40.

Vitamin E prevents diabetes-induced abnormal retinal blood flow via the diacylglycerol-protein kinase C pathway.

Kunisaki M, Bursell SE, Clermont AC, Ishii H, Ballas LM, Jirousek MR, Umeda F, Nawata H, King GL.

Am J Physiol. 1995 Aug;269(2 Pt 1):E239-46.

PMID:
7653541
41.

The in vivo effect of endothelins on retinal circulation in nondiabetic and diabetic rats.

Bursell SE, Clermont AC, Oren B, King GL.

Invest Ophthalmol Vis Sci. 1995 Mar;36(3):596-607.

PMID:
7890491
42.

Normalization of retinal blood flow in diabetic rats with primary intervention using insulin pumps.

Clermont AC, Brittis M, Shiba T, McGovern T, King GL, Bursell SE.

Invest Ophthalmol Vis Sci. 1994 Mar;35(3):981-90.

PMID:
8125761
43.

Vasodilation of rat retinal microvessels induced by monobutyrin. Dysregulation in diabetes.

Halvorsen YD, Bursell SE, Wilkison WO, Clermont AC, Brittis M, McGovern TJ, Spiegelman BM.

J Clin Invest. 1993 Dec;92(6):2872-6.

44.

Evaluating retinal circulation using video fluorescein angiography in control and diabetic rats.

Bursell SE, Clermont AC, Shiba T, King GL.

Curr Eye Res. 1992 Apr;11(4):287-95.

PMID:
1388117
45.

Blood glucose measurement by multiple attenuated total reflection and infrared absorption spectroscopy.

Mendelson Y, Clermont AC, Peura RA, Lin BC.

IEEE Trans Biomed Eng. 1990 May;37(5):458-65.

PMID:
2345001
46.

Carbon dioxide laser based multiple ATR technique for measuring glucose in aqueous solutions.

Mendelson Y, Lin BC, Peura RA, Clermont AC.

Appl Opt. 1988 Dec 15;27(24):5077-81. doi: 10.1364/AO.27.005077.

PMID:
20539699

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