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Items: 1 to 50 of 82

1.

Mass spectrometry imaging of endogenous metabolites in response to doxorubicin in a novel 3D osteosarcoma cell culture model.

Palubeckaitė I, Crooks L, Smith DP, Cole LM, Bram H, Le Maitre C, Clench MR, Cross NA.

J Mass Spectrom. 2019 Oct 26. doi: 10.1002/jms.4461. [Epub ahead of print]

PMID:
31654532
2.

Sample Treatment for Tissue Proteomics in Cancer, Toxicology, and Forensics.

Cole LM, Clench MR, Francese S.

Adv Exp Med Biol. 2019;1073:77-123. doi: 10.1007/978-3-030-12298-0_4. Review.

PMID:
31236840
3.

Investigation of infinite focus microscopy for the determination of the association of blood with fingermarks.

Deininger L, Francese S, Clench MR, Langenburg G, Sears V, Sammon C.

Sci Justice. 2018 Nov;58(6):397-404. doi: 10.1016/j.scijus.2018.07.001. Epub 2018 Jul 10.

PMID:
30446068
4.

Quantitative Investigation of Terbinafine Hydrochloride Absorption into a Living Skin Equivalent Model by MALDI-MSI.

Russo C, Brickelbank N, Duckett C, Mellor S, Rumbelow S, Clench MR.

Anal Chem. 2018 Aug 21;90(16):10031-10038. doi: 10.1021/acs.analchem.8b02648. Epub 2018 Aug 2.

PMID:
30024732
5.

Mass Spectrometry Imaging of 3D Tissue Models.

Russo C, Lewis EEL, Flint L, Clench MR.

Proteomics. 2018 Jul;18(14):e1700462. doi: 10.1002/pmic.201700462. Epub 2018 May 28.

PMID:
29687599
6.

Quantitation of Endogenous Metabolites in Mouse Tumors Using Mass-Spectrometry Imaging.

Swales JG, Dexter A, Hamm G, Nilsson A, Strittmatter N, Michopoulos F, Hardy C, Morentin-Gutierrez P, Mellor M, Andren PE, Clench MR, Bunch J, Critchlow SE, Goodwin RJA.

Anal Chem. 2018 May 15;90(10):6051-6058. doi: 10.1021/acs.analchem.7b05239. Epub 2018 Apr 26.

PMID:
29668267
7.

Discrimination of papillary thyroid cancer from non-cancerous thyroid tissue based on lipid profiling by mass spectrometry imaging.

Wojakowska A, Cole LM, Chekan M, Bednarczyk K, Maksymiak M, Oczko-Wojciechowska M, Jarząb B, Clench MR, Polańska J, Pietrowska M, Widlak P.

Endokrynol Pol. 2018;69(1):2-8. doi: 10.5603/EP.a2018.0003.

8.

Examination of the skin barrier repair/wound healing process using a living skin equivalent model and matrix-assisted laser desorption-ionization-mass spectrometry imaging.

Lewis EEL, Barrett MRT, Freeman-Parry L, Bojar RA, Clench MR.

Int J Cosmet Sci. 2018 Apr;40(2):148-156. doi: 10.1111/ics.12446. Epub 2018 Feb 28.

9.

Metabolomic analysis of white and yellow seminal plasma in turkeys (Meleagris gallopavo).

Slowinska M, Sallem H, Clench MR, Ciereszko A.

Poult Sci. 2018 Mar 1;97(3):1059-1065. doi: 10.3382/ps/pex366.

PMID:
29272520
10.

Optimization of Sample Preparation and Instrumental Parameters for the Rapid Analysis of Drugs of Abuse in Hair samples by MALDI-MS/MS Imaging.

Flinders B, Beasley E, Verlaan RM, Cuypers E, Francese S, Bassindale T, Clench MR, Heeren RMA.

J Am Soc Mass Spectrom. 2017 Nov;28(11):2462-2468. doi: 10.1007/s13361-017-1766-0. Epub 2017 Aug 11.

11.

MALDI-MSI of Lipids in Human Skin.

Hart PJ, Clench MR.

Methods Mol Biol. 2017;1618:29-36. doi: 10.1007/978-1-4939-7051-3_4.

PMID:
28523497
12.

Methanol adducts leading to the identification of a reactive aldehyde metabolite of CPAQOP in human liver microsomes by ultra-high-performance liquid chromatography/mass spectrometry.

Martin S, Lenz EM, Smith R, Temesi DG, Orton AL, Clench MR.

Rapid Commun Mass Spectrom. 2017 Jan 15;31(1):145-151. doi: 10.1002/rcm.7772.

PMID:
27943491
13.

Antigen retrieval prior to on-tissue digestion of formalin-fixed paraffin-embedded tumour tissue sections yields oxidation of proline residues.

Djidja MC, Claude E, Scriven P, Allen DW, Carolan VA, Clench MR.

Biochim Biophys Acta Proteins Proteom. 2017 Jul;1865(7):901-906. doi: 10.1016/j.bbapap.2016.11.019. Epub 2016 Dec 8.

PMID:
27939604
14.

Spatial Quantitation of Drugs in tissues using Liquid Extraction Surface Analysis Mass Spectrometry Imaging.

Swales JG, Strittmatter N, Tucker JW, Clench MR, Webborn PJH, Goodwin RJA.

Sci Rep. 2016 Nov 24;6:37648. doi: 10.1038/srep37648.

15.

Advances in mass spectrometry imaging.

Clench MR.

Proteomics. 2016 Jun;16(11-12):1605-6. doi: 10.1002/pmic.201600202. No abstract available.

PMID:
27303928
16.

MALDI-MSI for the analysis of a 3D tissue-engineered psoriatic skin model.

Harvey A, Cole LM, Day R, Bartlett M, Warwick J, Bojar R, Smith D, Cross N, Clench MR.

Proteomics. 2016 Jun;16(11-12):1718-25. doi: 10.1002/pmic.201600036.

17.

Proteomics goes forensic: Detection and mapping of blood signatures in fingermarks.

Deininger L, Patel E, Clench MR, Sears V, Sammon C, Francese S.

Proteomics. 2016 Jun;16(11-12):1707-17. doi: 10.1002/pmic.201500544.

PMID:
27125769
18.

Understanding metabolism of arginine in biological systems via MALDI imaging.

Walker HJ, Steels C, Bendell L, Clench MR, Read DJ, Cameron DD, Burrell MM.

Proteomics. 2016 Jun;16(11-12):1690-4. doi: 10.1002/pmic.201500493. Epub 2016 May 27.

PMID:
27061027
19.

MALDI MSI analysis of lipid changes in living skin equivalents in response to emollient creams containing palmitoylethanolamide.

Mitchell CA, Donaldson M, Francese S, Clench MR.

Methods. 2016 Jul 15;104:93-100. doi: 10.1016/j.ymeth.2016.02.001. Epub 2016 Feb 2.

PMID:
26845462
20.

A proteomic approach for the rapid, multi-informative and reliable identification of blood.

Patel E, Cicatiello P, Deininger L, Clench MR, Marino G, Giardina P, Langenburg G, West A, Marshall P, Sears V, Francese S.

Analyst. 2016 Jan 7;141(1):191-8. doi: 10.1039/c5an02016f. Epub 2015 Nov 24.

PMID:
26596622
22.

Mapping drug distribution in brain tissue using liquid extraction surface analysis mass spectrometry imaging.

Swales JG, Tucker JW, Spreadborough MJ, Iverson SL, Clench MR, Webborn PJ, Goodwin RJ.

Anal Chem. 2015 Oct 6;87(19):10146-52. doi: 10.1021/acs.analchem.5b02998. Epub 2015 Sep 30.

PMID:
26350423
23.

Mass spectrometry imaging tools in oncology.

Cole LM, Clench MR.

Biomark Med. 2015;9(9):863-8. doi: 10.2217/bmm.15.61. Epub 2015 Sep 2. Review.

PMID:
26330284
24.

Lipid changes within the epidermis of living skin equivalents observed across a time-course by MALDI-MS imaging and profiling.

Mitchell CA, Long H, Donaldson M, Francese S, Clench MR.

Lipids Health Dis. 2015 Aug 5;14:84. doi: 10.1186/s12944-015-0089-z.

25.

Erratum to: Alternative Surfactants for Improved Efficiency of In Situ Tryptic Proteolysis of Fingermarks.

Patel E, Clench MR, West A, Marshall PS, Marshall N, Francese S.

J Am Soc Mass Spectrom. 2015 Oct;26(10):1795. doi: 10.1007/s13361-015-1216-9. No abstract available.

26.

Alternative surfactants for improved efficiency of in situ tryptic proteolysis of fingermarks.

Patel E, Clench MR, West A, Marshall PS, Marshall N, Francese S.

J Am Soc Mass Spectrom. 2015 Jun;26(6):862-72. doi: 10.1007/s13361-015-1140-z. Epub 2015 Apr 28. Erratum in: J Am Soc Mass Spectrom. 2015 Oct;26(10):1795.

27.

Mass spectrometry imaging for the proteomic study of clinical tissue.

Cole LM, Clench MR.

Proteomics Clin Appl. 2015 Apr;9(3-4):335-41. doi: 10.1002/prca.201400103. Epub 2015 Mar 23. Review.

PMID:
25620724
28.

MALDI-MS imaging for the study of tissue pharmacodynamics and toxicodynamics.

Patel E, Cole LM, Bradshaw R, Batubara A, Mitchell CA, Francese S, Clench MR.

Bioanalysis. 2015;7(1):91-101. doi: 10.4155/bio.14.280.

PMID:
25558938
29.

The use of hydrazine-based derivatization reagents for improved sensitivity and detection of carbonyl containing compounds using MALDI-MSI.

Flinders B, Morrell J, Marshall PS, Ranshaw LE, Clench MR.

Anal Bioanal Chem. 2015 Mar;407(8):2085-94. doi: 10.1007/s00216-014-8223-8. Epub 2014 Nov 1.

PMID:
25366974
30.

Identification of the reactive metabolites of fenclozic acid in bile duct cannulated rats.

Martin S, Lenz EM, Keene W, Clench MR.

Anal Chem. 2014 Nov 18;86(22):11281-9. doi: 10.1021/ac502943d. Epub 2014 Oct 31.

PMID:
25321605
31.

"Afterlife experiment": use of MALDI-MS and SIMS imaging for the study of the nitrogen cycle within plants.

Seaman C, Flinders B, Eijkel G, Heeren RM, Bricklebank N, Clench MR.

Anal Chem. 2014 Oct 21;86(20):10071-7. doi: 10.1021/ac501191w. Epub 2014 Sep 30.

PMID:
25230319
32.

Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis.

Swales JG, Tucker JW, Strittmatter N, Nilsson A, Cobice D, Clench MR, Mackay CL, Andren PE, Takáts Z, Webborn PJ, Goodwin RJ.

Anal Chem. 2014 Aug 19;86(16):8473-80. doi: 10.1021/ac502217r. Epub 2014 Aug 8.

PMID:
25084360
33.

Radiation-induced changes in serum lipidome of head and neck cancer patients.

Jelonek K, Pietrowska M, Ros M, Zagdanski A, Suchwalko A, Polanska J, Marczyk M, Rutkowski T, Skladowski K, Clench MR, Widlak P.

Int J Mol Sci. 2014 Apr 17;15(4):6609-24. doi: 10.3390/ijms15046609.

34.

Direct detection of blood in fingermarks by MALDI MS profiling and imaging.

Bradshaw R, Bleay S, Clench MR, Francese S.

Sci Justice. 2014 Mar;54(2):110-7. doi: 10.1016/j.scijus.2013.12.004. Epub 2014 Jan 3.

PMID:
24630320
35.

MALDI-MSI and label-free LC-ESI-MS/MS shotgun proteomics to investigate protein induction in a murine fibrosarcoma model following treatment with a vascular disrupting agent.

Cole LM, Bluff JE, Carolan VA, Paley MN, Tozer GM, Clench MR.

Proteomics. 2014 Apr;14(7-8):890-903. doi: 10.1002/pmic.201300429.

PMID:
24520073
36.

Recombinant " IMS TAG" proteins--a new method for validating bottom-up matrix-assisted laser desorption/ionisation ion mobility separation mass spectrometry imaging.

Cole LM, Mahmoud K, Haywood-Small S, Tozer GM, Smith DP, Clench MR.

Rapid Commun Mass Spectrom. 2013 Nov 15;27(21):2355-62. doi: 10.1002/rcm.6693.

PMID:
24097391
37.

Towards the integration of matrix assisted laser desorption ionisation mass spectrometry imaging into the current fingermark examination workflow.

Bradshaw R, Bleay S, Wolstenholme R, Clench MR, Francese S.

Forensic Sci Int. 2013 Oct 10;232(1-3):111-24. doi: 10.1016/j.forsciint.2013.07.013. Epub 2013 Aug 9.

PMID:
24053872
38.
39.

Efficiency of the dry-wet method for the MALDI-MSI analysis of latent fingermarks.

Ferguson LS, Creasey S, Wolstenholme R, Clench MR, Francese S.

J Mass Spectrom. 2013 Jun;48(6):677-84. doi: 10.1002/jms.3216.

PMID:
23722958
40.

Metabolomics in toxicology and preclinical research.

Ramirez T, Daneshian M, Kamp H, Bois FY, Clench MR, Coen M, Donley B, Fischer SM, Ekman DR, Fabian E, Guillou C, Heuer J, Hogberg HT, Jungnickel H, Keun HC, Krennrich G, Krupp E, Luch A, Noor F, Peter E, Riefke B, Seymour M, Skinner N, Smirnova L, Verheij E, Wagner S, Hartung T, van Ravenzwaay B, Leist M.

ALTEX. 2013;30(2):209-25. doi: 10.14573/altex.2013.2.209.

41.

Beyond the ridge pattern: multi-informative analysis of latent fingermarks by MALDI mass spectrometry.

Francese S, Bradshaw R, Ferguson LS, Wolstenholme R, Clench MR, Bleay S.

Analyst. 2013 Aug 7;138(15):4215-28. doi: 10.1039/c3an36896c. Epub 2013 May 9. Review.

PMID:
23658933
42.

Curcumin: a multipurpose matrix for MALDI mass spectrometry imaging applications.

Francese S, Bradshaw R, Flinders B, Mitchell C, Bleay S, Cicero L, Clench MR.

Anal Chem. 2013 May 21;85(10):5240-8. doi: 10.1021/ac4007396. Epub 2013 May 10.

PMID:
23621442
43.

Spectroscopic imaging based approach for condom identification in condom contaminated fingermarks.

Bradshaw R, Wolstenholme R, Ferguson LS, Sammon C, Mader K, Claude E, Blackledge RD, Clench MR, Francese S.

Analyst. 2013 May 7;138(9):2546-57. doi: 10.1039/c3an00195d.

PMID:
23486747
44.

Direct detection of peptides and small proteins in fingermarks and determination of sex by MALDI mass spectrometry profiling.

Ferguson LS, Wulfert F, Wolstenholme R, Fonville JM, Clench MR, Carolan VA, Francese S.

Analyst. 2012 Oct 21;137(20):4686-92. doi: 10.1039/c2an36074h.

PMID:
22950080
45.

Separation of overlapping fingermarks by matrix assisted laser desorption ionisation mass spectrometry imaging.

Bradshaw R, Rao W, Wolstenholme R, Clench MR, Bleay S, Francese S.

Forensic Sci Int. 2012 Oct 10;222(1-3):318-26. doi: 10.1016/j.forsciint.2012.07.009. Epub 2012 Aug 11.

PMID:
22889915
46.

Instrumentation and software for mass spectrometry imaging--making the most of what you've got.

Trim PJ, Djidja MC, Muharib T, Cole LM, Flinders B, Carolan VA, Francese S, Clench MR.

J Proteomics. 2012 Aug 30;75(16):4931-4940. doi: 10.1016/j.jprot.2012.07.016. Epub 2012 Jul 20. Review.

PMID:
22820537
47.

Reaction of homopiperazine with endogenous formaldehyde: a carbon hydrogen addition metabolite/product identified in rat urine and blood.

Martin S, Lenz EM, Temesi D, Wild M, Clench MR.

Drug Metab Dispos. 2012 Aug;40(8):1478-86. doi: 10.1124/dmd.112.044917. Epub 2012 May 1.

PMID:
22550270
48.

Effects of bioactive compounds from carrots (Daucus carota L.), polyacetylenes, beta-carotene and lutein on human lymphoid leukaemia cells.

Zaini RG, Brandt K, Clench MR, Le Maitre CL.

Anticancer Agents Med Chem. 2012 Jul;12(6):640-52.

PMID:
22263789
49.

Bioactive actions of pomegranate fruit extracts on leukemia cell lines in vitro hold promise for new therapeutic agents for leukemia.

Dahlawi H, Jordan-Mahy N, Clench MR, Le Maitre CL.

Nutr Cancer. 2012;64(1):100-10. doi: 10.1080/01635581.2012.630155. Epub 2011 Nov 18.

PMID:
22098126
50.

Bioactive chemicals from carrot (Daucus carota) juice extracts for the treatment of leukemia.

Zaini R, Clench MR, Le Maitre CL.

J Med Food. 2011 Nov;14(11):1303-12. doi: 10.1089/jmf.2010.0284. Epub 2011 Aug 24.

PMID:
21864090

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