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Items: 15


A Recombinant Subunit Based Zika Virus Vaccine Is Efficacious in Non-human Primates.

Medina LO, To A, Lieberman MM, Wong TAS, Namekar M, Nakano E, Andersen H, Yalley-Ogunro J, Greenhouse J, Higgs S, Huang YS, Vanlandingham DL, Horton JS, Clements DE, Lehrer AT.

Front Immunol. 2018 Nov 8;9:2464. doi: 10.3389/fimmu.2018.02464. eCollection 2018.


A combination of TLR-4 agonist and saponin adjuvants increases antibody diversity and protective efficacy of a recombinant West Nile Virus antigen.

Van Hoeven N, Wiley S, Gage E, Fiore-Gartland A, Granger B, Gray S, Fox C, Clements DE, Parks DE, Winram S, Stinchcomb DT, Reed SG, Coler RN.

NPJ Vaccines. 2018 Sep 26;3:39. doi: 10.1038/s41541-018-0077-1. eCollection 2018.


Recombinant proteins of Zaire ebolavirus induce potent humoral and cellular immune responses and protect against live virus infection in mice.

Lehrer AT, Wong TS, Lieberman MM, Humphreys T, Clements DE, Bakken RR, Hart MK, Pratt WD, Dye JM.

Vaccine. 2018 May 24;36(22):3090-3100. doi: 10.1016/j.vaccine.2017.01.068. Epub 2017 Feb 16.


A Novel Synthetic TLR-4 Agonist Adjuvant Increases the Protective Response to a Clinical-Stage West Nile Virus Vaccine Antigen in Multiple Formulations.

Van Hoeven N, Joshi SW, Nana GI, Bosco-Lauth A, Fox C, Bowen RA, Clements DE, Martyak T, Parks DE, Baldwin S, Reed SG, Coler RN.

PLoS One. 2016 Feb 22;11(2):e0149610. doi: 10.1371/journal.pone.0149610. eCollection 2016.


Preclinical and clinical development of a dengue recombinant subunit vaccine.

Manoff SB, George SL, Bett AJ, Yelmene ML, Dhanasekaran G, Eggemeyer L, Sausser ML, Dubey SA, Casimiro DR, Clements DE, Martyak T, Pai V, Parks DE, Coller BA.

Vaccine. 2015 Dec 10;33(50):7126-34. doi: 10.1016/j.vaccine.2015.09.101. Epub 2015 Oct 14. Review.


Preclinical development of a dengue tetravalent recombinant subunit vaccine: Immunogenicity and protective efficacy in nonhuman primates.

Govindarajan D, Meschino S, Guan L, Clements DE, ter Meulen JH, Casimiro DR, Coller BA, Bett AJ.

Vaccine. 2015 Aug 7;33(33):4105-16. doi: 10.1016/j.vaccine.2015.06.067. Epub 2015 Jul 3.


T cell epitope regions of the P. falciparum MSP1-33 critically influence immune responses and in vitro efficacy of MSP1-42 vaccines.

Pusic KM, Hashimoto CN, Lehrer A, Aniya C, Clements DE, Hui GS.

PLoS One. 2011;6(9):e24782. doi: 10.1371/journal.pone.0024782. Epub 2011 Sep 13.


The development of recombinant subunit envelope-based vaccines to protect against dengue virus induced disease.

Coller BA, Clements DE, Bett AJ, Sagar SL, Ter Meulen JH.

Vaccine. 2011 Sep 23;29(42):7267-75. doi: 10.1016/j.vaccine.2011.07.021. Epub 2011 Jul 21. Review.


Dengue vaccines: progress and challenges.

Coller BA, Clements DE.

Curr Opin Immunol. 2011 Jun;23(3):391-8. doi: 10.1016/j.coi.2011.03.005. Epub 2011 Apr 21. Review.


Advances in flavivirus vaccine development.

Coller BA, Clements DE, Martyak T, Yelmene M, Thorne M, Parks DE.

IDrugs. 2010 Dec;13(12):880-4. Review.


Development of a recombinant tetravalent dengue virus vaccine: immunogenicity and efficacy studies in mice and monkeys.

Clements DE, Coller BA, Lieberman MM, Ogata S, Wang G, Harada KE, Putnak JR, Ivy JM, McDonell M, Bignami GS, Peters ID, Leung J, Weeks-Levy C, Nakano ET, Humphreys T.

Vaccine. 2010 Mar 24;28(15):2705-15. doi: 10.1016/j.vaccine.2010.01.022. Epub 2010 Jan 22.


Efficacy and durability of a recombinant subunit West Nile vaccine candidate in protecting hamsters from West Nile encephalitis.

Watts DM, Tesh RB, Siirin M, Rosa AT, Newman PC, Clements DE, Ogata S, Coller BA, Weeks-Levy C, Lieberman MM.

Vaccine. 2007 Apr 12;25(15):2913-8. Epub 2006 Aug 22.


Preparation and immunogenic properties of a recombinant West Nile subunit vaccine.

Lieberman MM, Clements DE, Ogata S, Wang G, Corpuz G, Wong T, Martyak T, Gilson L, Coller BA, Leung J, Watts DM, Tesh RB, Siirin M, Travassos da Rosa A, Humphreys T, Weeks-Levy C.

Vaccine. 2007 Jan 5;25(3):414-23. Epub 2006 Aug 30.


Use of recombinant envelope proteins for serological diagnosis of Dengue virus infection in an immunochromatographic assay.

Cuzzubbo AJ, Endy TP, Nisalak A, Kalayanarooj S, Vaughn DW, Ogata SA, Clements DE, Devine PL.

Clin Diagn Lab Immunol. 2001 Nov;8(6):1150-5.


Multiple copies of a DNA sequence from Pseudomonas syringae pathovar phaseolicola abolish thermoregulation of phaseolotoxin production.

Rowley KB, Clements DE, Mandel M, Humphreys T, Patil SS.

Mol Microbiol. 1993 May;8(3):625-35.


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