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Items: 1 to 50 of 60

1.

Protein corona formation and its constitutional changes on magnetic nanoparticles in serum featuring a polydehydroalanine coating: effects of charge and incubation conditions.

Gräfe C, von der Lühe M, Weidner A, Globig P, Clement JH, Dutz S, Schacher FH.

Nanotechnology. 2019 Jun 28;30(26):265707. doi: 10.1088/1361-6528/ab0ed0. Epub 2019 Mar 12.

PMID:
30861506
2.

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors.

George J, Walter V, Peifer M, Alexandrov LB, Seidel D, Leenders F, Maas L, Müller C, Dahmen I, Delhomme TM, Ardin M, Leblay N, Byrnes G, Sun R, De Reynies A, McLeer-Florin A, Bosco G, Malchers F, Menon R, Altmüller J, Becker C, Nürnberg P, Achter V, Lang U, Schneider PM, Bogus M, Soloway MG, Wilkerson MD, Cun Y, McKay JD, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Lemaitre N, Soltermann A, Weder W, Tischler V, Brustugun OT, Lund-Iversen M, Helland Å, Solberg S, Ansén S, Wright G, Solomon B, Roz L, Pastorino U, Petersen I, Clement JH, Sänger J, Wolf J, Vingron M, Zander T, Perner S, Travis WD, Haas SA, Olivier M, Foll M, Büttner R, Hayes DN, Brambilla E, Fernandez-Cuesta L, Thomas RK.

Nat Commun. 2018 Mar 13;9(1):1048. doi: 10.1038/s41467-018-03099-x.

3.

Magnetic Nanoparticles Interact and Pass an In Vitro Co-Culture Blood-Placenta Barrier Model.

Müller EK, Gräfe C, Wiekhorst F, Bergemann C, Weidner A, Dutz S, Clement JH.

Nanomaterials (Basel). 2018 Feb 14;8(2). pii: E108. doi: 10.3390/nano8020108.

4.

Influence of Sterilization and Preservation Procedures on the Integrity of Serum Protein-Coated Magnetic Nanoparticles.

Dutz S, Wojahn S, Gräfe C, Weidner A, Clement JH.

Nanomaterials (Basel). 2017 Dec 15;7(12). pii: E453. doi: 10.3390/nano7120453.

5.

RHEB1 insufficiency in aged male mice is associated with stress-induced seizures.

Tian Q, Gromov P, Clement JH, Wang Y, Riemann M, Weih F, Sun XX, Dai MS, Fedorov LM.

Geroscience. 2017 Dec;39(5-6):557-570. doi: 10.1007/s11357-017-9997-3. Epub 2017 Sep 10.

6.

Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis.

Göhring AR, Reuter S, Clement JH, Cheng X, Theobald J, Wölfl S, Mrowka R.

PLoS One. 2017 Apr 20;12(4):e0174912. doi: 10.1371/journal.pone.0174912. eCollection 2017.

7.

Comprehensive analysis of the in vitro and ex ovo hemocompatibility of surface engineered iron oxide nanoparticles for biomedical applications.

Schlenk F, Werner S, Rabel M, Jacobs F, Bergemann C, Clement JH, Fischer D.

Arch Toxicol. 2017 Oct;91(10):3271-3286. doi: 10.1007/s00204-017-1968-z. Epub 2017 Apr 4.

PMID:
28378120
8.

Zwitterionic Iron Oxide (γ-Fe2 O3 ) Nanoparticles Based on P(2VP-grad-AA) Copolymers.

Billing M, Gräfe C, Saal A, Biehl P, Clement JH, Dutz S, Weidner S, Schacher FH.

Macromol Rapid Commun. 2017 Feb;38(4). doi: 10.1002/marc.201600637. Epub 2016 Dec 22.

PMID:
28004458
9.

Recognition of tumor cells by immuno-SERS-markers in a microfluidic chip at continuous flow.

Freitag I, Beleites C, Dochow S, Clement JH, Krafft C, Popp J.

Analyst. 2016 Oct 17;141(21):5986-5989.

PMID:
27722229
10.

Magnetic particle spectroscopy allows precise quantification of nanoparticles after passage through human brain microvascular endothelial cells.

Gräfe C, Slabu I, Wiekhorst F, Bergemann C, von Eggeling F, Hochhaus A, Trahms L, Clement JH.

Phys Med Biol. 2016 Jun 7;61(11):3986-4000. doi: 10.1088/0031-9155/61/11/3986. Epub 2016 May 10.

PMID:
27163489
11.

RHEB1 expression in embryonic and postnatal mouse.

Tian Q, Smart JL, Clement JH, Wang Y, Derkatch A, Schubert H, Danilchik MV, Marks DL, Fedorov LM.

Histochem Cell Biol. 2016 May;145(5):561-72. doi: 10.1007/s00418-015-1394-3. Epub 2015 Dec 26.

PMID:
26708151
12.

Intentional formation of a protein corona on nanoparticles: Serum concentration affects protein corona mass, surface charge, and nanoparticle-cell interaction.

Gräfe C, Weidner A, Lühe MV, Bergemann C, Schacher FH, Clement JH, Dutz S.

Int J Biochem Cell Biol. 2016 Jun;75:196-202. doi: 10.1016/j.biocel.2015.11.005. Epub 2015 Nov 10.

PMID:
26556312
13.

Preparation of Core-Shell Hybrid Materials by Producing a Protein Corona Around Magnetic Nanoparticles.

Weidner A, Gräfe C, von der Lühe M, Remmer H, Clement JH, Eberbeck D, Ludwig F, Müller R, Schacher FH, Dutz S.

Nanoscale Res Lett. 2015 Dec;10(1):992. doi: 10.1186/s11671-015-0992-2. Epub 2015 Jul 8.

14.

Magnetic Biocomposites for Remote Melting.

Zhou M, Liebert T, Müller R, Dellith A, Gräfe C, Clement JH, Heinze T.

Biomacromolecules. 2015 Aug 10;16(8):2308-15. doi: 10.1021/acs.biomac.5b00540. Epub 2015 Jul 20.

PMID:
26134099
15.

Differentiation of MCF-7 tumor cells from leukocytes and fibroblast cells using epithelial cell adhesion molecule targeted multicore surface-enhanced Raman spectroscopy labels.

Freitag I, Matthäus C, Csaki A, Clement JH, Cialla-May D, Weber K, Krafft C, Popp J.

J Biomed Opt. 2015 May;20(5):55002. doi: 10.1117/1.JBO.20.5.055002.

PMID:
25938206
16.

KRAS mutation screening by chip-based DNA hybridization--a further step towards personalized oncology.

Steinbach C, Steinbrücker C, Pollok S, Walther K, Clement JH, Chen Y, Petersen I, Cialla-May D, Weber K, Popp J.

Analyst. 2015 Apr 21;140(8):2747-54. doi: 10.1039/c4an02086c. Epub 2015 Feb 23.

PMID:
25706807
17.

Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data.

Fernandez-Cuesta L, Sun R, Menon R, George J, Lorenz S, Meza-Zepeda LA, Peifer M, Plenker D, Heuckmann JM, Leenders F, Zander T, Dahmen I, Koker M, Schöttle J, Ullrich RT, Altmüller J, Becker C, Nürnberg P, Seidel H, Böhm D, Göke F, Ansén S, Russell PA, Wright GM, Wainer Z, Solomon B, Petersen I, Clement JH, Sänger J, Brustugun OT, Helland Å, Solberg S, Lund-Iversen M, Buettner R, Wolf J, Brambilla E, Vingron M, Perner S, Haas SA, Thomas RK.

Genome Biol. 2015 Jan 5;16:7. doi: 10.1186/s13059-014-0558-0.

18.

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia.

Frietsch JJ, Kastner C, Grunewald TG, Schweigel H, Nollau P, Ziermann J, Clement JH, La Rosée P, Hochhaus A, Butt E.

Oncotarget. 2014 Jul 30;5(14):5257-71.

19.

CD74-NRG1 fusions in lung adenocarcinoma.

Fernandez-Cuesta L, Plenker D, Osada H, Sun R, Menon R, Leenders F, Ortiz-Cuaran S, Peifer M, Bos M, Daßler J, Malchers F, Schöttle J, Vogel W, Dahmen I, Koker M, Ullrich RT, Wright GM, Russell PA, Wainer Z, Solomon B, Brambilla E, Nagy-Mignotte H, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Altmüller J, Becker C, Nürnberg P, Heuckmann JM, Stoelben E, Petersen I, Clement JH, Sänger J, Muscarella LA, la Torre A, Fazio VM, Lahortiga I, Perera T, Ogata S, Parade M, Brehmer D, Vingron M, Heukamp LC, Buettner R, Zander T, Wolf J, Perner S, Ansén S, Haas SA, Yatabe Y, Thomas RK.

Cancer Discov. 2014 Apr;4(4):415-22. doi: 10.1158/2159-8290.CD-13-0633. Epub 2014 Jan 27.

20.

Novel platinum(II) compounds with O,S bidentate ligands: synthesis, characterization, antiproliferative properties and biomolecular interactions.

Mügge C, Liu R, Görls H, Gabbiani C, Michelucci E, Rüdiger N, Clement JH, Messori L, Weigand W.

Dalton Trans. 2014 Feb 28;43(8):3072-86. doi: 10.1039/c3dt52284a.

PMID:
24169734
21.

Temperature: the "ignored" factor at the NanoBio interface.

Mahmoudi M, Abdelmonem AM, Behzadi S, Clement JH, Dutz S, Ejtehadi MR, Hartmann R, Kantner K, Linne U, Maffre P, Metzler S, Moghadam MK, Pfeiffer C, Rezaei M, Ruiz-Lozano P, Serpooshan V, Shokrgozar MA, Nienhaus GU, Parak WJ.

ACS Nano. 2013 Aug 27;7(8):6555-62. doi: 10.1021/nn305337c. Epub 2013 Jul 10.

PMID:
23808533
22.

Paradoxical MAPK-activation in response to treatment with tyrosine kinase inhibitors in CML: flow cytometry loses track.

Schnetzke U, Fischer M, Frietsch JJ, Finkensieper A, Clement JH, Hochhaus A, La Rosée P.

Cytometry B Clin Cytom. 2014 Jul;86(4):229-35. doi: 10.1002/cyto.b.21091. Epub 2013 Apr 10.

23.

Biocompatible multishell architecture for iron oxide nanoparticles.

Wotschadlo J, Liebert T, Clement JH, Anspach N, Höppener S, Rudolph T, Müller R, Schacher FH, Schubert US, Heinze T.

Macromol Biosci. 2013 Jan;13(1):93-105. doi: 10.1002/mabi.201200243. Epub 2012 Nov 19.

PMID:
23161745
24.

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.

Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann JM, Lu X, Carter SL, Cibulskis K, Banerji S, Getz G, Park KS, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z, Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella LA, Fazio VM, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman DA, Snijders PJ, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun OT, Lund-Iversen M, Sänger J, Clement JH, Soltermann A, Moch H, Weder W, Solomon B, Soria JC, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider PM, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Nürnberg P, Perner S, Heukamp LC, Brindle PK, Haas S, Thomas RK.

Nat Genet. 2012 Oct;44(10):1104-10. doi: 10.1038/ng.2396. Epub 2012 Sep 2.

25.

Amino-functionalized cellulose nanoparticles: preparation, characterization, and interactions with living cells.

Nikolajski M, Wotschadlo J, Clement JH, Heinze T.

Macromol Biosci. 2012 Jul;12(7):920-5. doi: 10.1002/mabi.201200040. Epub 2012 Apr 25.

PMID:
22535832
26.

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.

Hammerman PS, Sos ML, Ramos AH, Xu C, Dutt A, Zhou W, Brace LE, Woods BA, Lin W, Zhang J, Deng X, Lim SM, Heynck S, Peifer M, Simard JR, Lawrence MS, Onofrio RC, Salvesen HB, Seidel D, Zander T, Heuckmann JM, Soltermann A, Moch H, Koker M, Leenders F, Gabler F, Querings S, Ansén S, Brambilla E, Brambilla C, Lorimier P, Brustugun OT, Helland A, Petersen I, Clement JH, Groen H, Timens W, Sietsma H, Stoelben E, Wolf J, Beer DG, Tsao MS, Hanna M, Hatton C, Eck MJ, Janne PA, Johnson BE, Winckler W, Greulich H, Bass AJ, Cho J, Rauh D, Gray NS, Wong KK, Haura EB, Thomas RK, Meyerson M.

Cancer Discov. 2011 Jun;1(1):78-89. doi: 10.1158/2159-8274.CD-11-0005.

27.

Towards detection and identification of circulating tumour cells using Raman spectroscopy.

Neugebauer U, Bocklitz T, Clement JH, Krafft C, Popp J.

Analyst. 2010 Dec;135(12):3178-82. doi: 10.1039/c0an00608d. Epub 2010 Oct 13.

PMID:
20941448
28.

Identification and differentiation of single cells from peripheral blood by Raman spectroscopic imaging.

Neugebauer U, Clement JH, Bocklitz T, Krafft C, Popp J.

J Biophotonics. 2010 Aug;3(8-9):579-87. doi: 10.1002/jbio.201000020.

PMID:
20449831
29.

Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS).

Escher N, Ernst G, Melle C, Berndt A, Clement JH, Junker K, Friedrich K, Guntinas-Lichius O, von Eggeling F.

Diagn Pathol. 2010 Jan 28;5:10. doi: 10.1186/1746-1596-5-10.

30.

Differential expression of cancer-related genes by single and permanent exposure to bone morphogenetic protein 2.

Steinert S, Kroll TC, Taubert I, Pusch L, Hortschansky P, Höffken K, Wölfl S, Clement JH.

J Cancer Res Clin Oncol. 2008 Nov;134(11):1237-45. doi: 10.1007/s00432-008-0396-0. Epub 2008 Apr 30.

PMID:
18446370
31.

Additive effects of PI3-kinase and MAPK activities on NB4 cell granulocyte differentiation: potential role of phosphatidylinositol 3-kinase gamma.

Scholl S, Bondeva T, Liu Y, Clement JH, Höffken K, Wetzker R.

J Cancer Res Clin Oncol. 2008 Aug;134(8):861-72. doi: 10.1007/s00432-008-0356-8. Epub 2008 Feb 21.

PMID:
18288489
32.

Rapid screening and sensitive detection of NPM1 (nucleophosmin) exon 12 mutations in acute myeloid leukaemia.

Scholl S, Mügge LO, Landt O, Loncarevic IF, Kunert C, Clement JH, Höffken K.

Leuk Res. 2007 Sep;31(9):1205-11. Epub 2007 Feb 15.

PMID:
17306368
33.

ATRA can enhance apoptosis that is induced by Flt3 tyrosine kinase inhibition in Flt3-ITD positive cells.

Scholl S, Müller R, Clement JH, Loncarevic IF, Böhmer FD, Höffken K.

Leuk Res. 2006 May;30(5):633-42. Epub 2006 Feb 13.

PMID:
16473406
34.

Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells.

Clement JH, Schwalbe M, Buske N, Wagner K, Schnabelrauch M, Görnert P, Kliche KO, Pachmann K, Weitschies W, Höffken K.

J Cancer Res Clin Oncol. 2006 May;132(5):287-92. Epub 2006 Jan 24.

PMID:
16432758
35.

Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis.

Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Niederwieser D, Harris AL.

J Cancer Res Clin Oncol. 2005 Nov;131(11):741-50. Epub 2005 Nov 1.

PMID:
16136355
36.

Bone morphogenetic protein 2 (BMP-2) induces in vitro invasion and in vivo hormone independent growth of breast carcinoma cells.

Clement JH, Raida M, Sänger J, Bicknell R, Liu J, Naumann A, Geyer A, Waldau A, Hortschansky P, Schmidt A, Höffken K, Wölft S, Harris AL.

Int J Oncol. 2005 Aug;27(2):401-7.

PMID:
16010421
37.

Standardized quantification of circulating peripheral tumor cells from lung and breast cancer.

Pachmann K, Clement JH, Schneider CP, Willen B, Camara O, Pachmann U, Höffken K.

Clin Chem Lab Med. 2005;43(6):617-27.

PMID:
16006258
38.

Specific detection of Flt3 point mutations by highly sensitive real-time polymerase chain reaction in acute myeloid leukemia.

Scholl S, Krause C, Loncarevic IF, Müller R, Kunert C, Wedding U, Sayer HG, Clement JH, Höffken K.

J Lab Clin Med. 2005 Jun;145(6):295-304.

PMID:
15976757
39.

Minimal residual disease based on patient specific Flt3-ITD and -ITT mutations in acute myeloid leukemia.

Scholl S, Loncarevic IF, Krause C, Kunert C, Clement JH, Höffken K.

Leuk Res. 2005 Jul;29(7):849-53.

PMID:
15921740
40.

Expression of bone morphogenetic protein 2 in breast cancer cells inhibits hypoxic cell death.

Raida M, Clement JH, Ameri K, Han C, Leek RD, Harris AL.

Int J Oncol. 2005 Jun;26(6):1465-70.

PMID:
15870857
41.

Cherubism - new hypotheses on pathogenesis and therapeutic consequences.

Hyckel P, Berndt A, Schleier P, Clement JH, Beensen V, Peters H, Kosmehl H.

J Craniomaxillofac Surg. 2005 Feb;33(1):61-8. Epub 2005 Jan 12.

PMID:
15694152
42.

Analyses of minimal residual disease based on Flt3 mutations in allogeneic peripheral blood stem cell transplantation.

Scholl S, Loncarevic IF, Krause C, Clement JH, Höffken K, Sayer HG.

J Cancer Res Clin Oncol. 2005 May;131(5):279-83. Epub 2005 Jan 11.

PMID:
15645287
43.

Increase of interleukin-18 serum levels after engraftment correlates with acute graft-versus-host disease in allogeneic peripheral blood stem cell transplantation.

Scholl S, Sayer HG, Mügge LO, Kasper C, Pietraszczyk M, Kliche KO, Clement JH, Höffken K.

J Cancer Res Clin Oncol. 2004 Dec;130(12):704-10. Epub 2004 Sep 7.

PMID:
15365821
44.

Differential expression and regulation of bone morphogenetic protein 7 in breast cancer.

Schwalbe M, Sänger J, Eggers R, Naumann A, Schmidt A, Höffken K, Clement JH.

Int J Oncol. 2003 Jul;23(1):89-95.

PMID:
12792780
45.

Heterogenic molecular basis for loss of ABL1-BCR transcription: deletions in der(9)t(9;22) and variants of standard t(9;22) in BCR-ABL1-positive chronic myeloid leukemia.

Loncarevic IF, Römer J, Starke H, Heller A, Bleck C, Ziegler M, Fiedler W, Liehr T, Clement JH, Claussen U.

Genes Chromosomes Cancer. 2002 Jun;34(2):193-200.

PMID:
11979553
46.

Molecular characterization of breast cancer cell lines by expression profiling.

Kroll T, Odyvanova L, Clement JH, Platzer C, Naumann A, Marr N, Höffken K, Wölfl S.

J Cancer Res Clin Oncol. 2002 Mar;128(3):125-34. Epub 2002 Jan 9.

PMID:
11935298
47.

Circadian variation of dihydropyrimidine dehydrogenase mRNA expression in leukocytes and serum cortisol levels in patients with advanced gastrointestinal carcinomas compared to healthy controls.

Raida M, Kliche KO, Schwabe W, Häusler P, Clement JH, Behnke D, Höffken K.

J Cancer Res Clin Oncol. 2002 Feb;128(2):96-102. Epub 2001 Nov 30.

PMID:
11862480
48.

Molecular cytogenetic characterization of an acquired minute supernumerary marker chromosome as the sole abnormality in a case clinically diagnosed as atypical Philadelphia-negative chronic myelogenous leukaemia.

Starke H, Raida M, Trifonov V, Clement JH, Loncarevic IF, Heller A, Bleck C, Nietzel A, Rubtsov N, Claussen U, Liehr T.

Br J Haematol. 2001 May;113(2):435-8.

PMID:
11380412
49.

Quality assurance in RT-PCR-based BCR/ABL diagnostics--results of an interlaboratory test and a standardization approach.

Burmeister T, Maurer J, Aivado M, Elmaagacli AH, Grünebach F, Held KR, Hess G, Hochhaus A, Höppner W, Lentes KU, Lübbert M, Schäfer KL, Schafhausen P, Schmidt CA, Schüler F, Seeger K, Seelig R, Thiede C, Viehmann S, Weber C, Wilhelm S, Christmann A, Clement JH, Ebener U, Enczmann J, Leo R, Schleuning M, Schoch R, Thiel E.

Leukemia. 2000 Oct;14(10):1850-6.

PMID:
11021760
50.

Bone morphogenetic protein 2 (BMP-2) induces sequential changes of Id gene expression in the breast cancer cell line MCF-7.

Clement JH, Marr N, Meissner A, Schwalbe M, Sebald W, Kliche KO, Höffken K, Wölfl S.

J Cancer Res Clin Oncol. 2000 May;126(5):271-9.

PMID:
10815762

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