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Items: 37


Elpistostege and the origin of the vertebrate hand.

Cloutier R, Clement AM, Lee MSY, Noël R, Béchard I, Roy V, Long JA.

Nature. 2020 Mar;579(7800):549-554. doi: 10.1038/s41586-020-2100-8. Epub 2020 Mar 18.


The Sigma-1 Receptor at the Crossroad of Proteostasis, Neurodegeneration, and Autophagy.

Christ MG, Clement AM, Behl C.

Trends Neurosci. 2020 Feb;43(2):79-81. doi: 10.1016/j.tins.2019.12.002. Epub 2020 Jan 6.


The phylogenetic significance of the morphology of the syrinx, hyoid and larynx, of the southern cassowary, Casuarius casuarius (Aves, Palaeognathae).

McInerney PL, Lee MSY, Clement AM, Worthy TH.

BMC Evol Biol. 2019 Dec 27;19(1):233. doi: 10.1186/s12862-019-1544-7.


A high latitude Devonian lungfish, from the Famennian of South Africa.

Gess RW, Clement AM.

PeerJ. 2019 Dec 4;7:e8073. doi: 10.7717/peerj.8073. eCollection 2019.


A protein quality control pathway regulated by linear ubiquitination.

van Well EM, Bader V, Patra M, Sánchez-Vicente A, Meschede J, Furthmann N, Schnack C, Blusch A, Longworth J, Petrasch-Parwez E, Mori K, Arzberger T, Trümbach D, Angersbach L, Showkat C, Sehr DA, Berlemann LA, Goldmann P, Clement AM, Behl C, Woerner AC, Saft C, Wurst W, Haass C, Ellrichmann G, Gold R, Dittmar G, Hipp MS, Hartl FU, Tatzelt J, Winklhofer KF.

EMBO J. 2019 May 2;38(9). pii: e100730. doi: 10.15252/embj.2018100730. Epub 2019 Mar 18.


Neurocranial anatomy of an enigmatic Early Devonian fish sheds light on early osteichthyan evolution.

Clement AM, King B, Giles S, Choo B, Ahlberg PE, Young GC, Long JA.

Elife. 2018 May 29;7. pii: e34349. doi: 10.7554/eLife.34349.


Cephalic muscle development in the Australian lungfish, Neoceratodus forsteri.

Ziermann JM, Clement AM, Ericsson R, Olsson L.

J Morphol. 2018 Apr;279(4):494-516. doi: 10.1002/jmor.20784. Epub 2017 Dec 7.


The cranial endocast of Dipnorhynchus sussmilchi (Sarcopterygii: Dipnoi) and the interrelationships of stem-group lungfishes.

Clement AM, Challands TJ, Long JA, Ahlberg PE.

PeerJ. 2016 Oct 20;4:e2539. eCollection 2016.


Progranulin overexpression in sensory neurons attenuates neuropathic pain in mice: Role of autophagy.

Altmann C, Hardt S, Fischer C, Heidler J, Lim HY, Häussler A, Albuquerque B, Zimmer B, Möser C, Behrends C, Koentgen F, Wittig I, Schmidt MHH, Clement AM, Deller T, Tegeder I.

Neurobiol Dis. 2016 Dec;96:294-311. doi: 10.1016/j.nbd.2016.09.010. Epub 2016 Sep 11.


A new method for reconstructing brain morphology: applying the brain-neurocranial spatial relationship in an extant lungfish to a fossil endocast.

Clement AM, Strand R, Nysjö J, Long JA, Ahlberg PE.

R Soc Open Sci. 2016 Jul 20;3(7):160307. doi: 10.1098/rsos.160307. eCollection 2016 Jul.


Brain - Endocast Relationship in the Australian Lungfish, Neoceratodus forsteri, Elucidated from Tomographic Data (Sarcopterygii: Dipnoi).

Clement AM, Nysjö J, Strand R, Ahlberg PE.

PLoS One. 2015 Oct 22;10(10):e0141277. doi: 10.1371/journal.pone.0141277. eCollection 2015.


Expression of the ALS-causing variant hSOD1(G93A) leads to an impaired integrity and altered regulation of claudin-5 expression in an in vitro blood-spinal cord barrier model.

Meister S, Storck SE, Hameister E, Behl C, Weggen S, Clement AM, Pietrzik CU.

J Cereb Blood Flow Metab. 2015 Jul;35(7):1112-21. doi: 10.1038/jcbfm.2015.57. Epub 2015 Apr 8.


Low-frequency magnetic fields do not aggravate disease in mouse models of Alzheimer's disease and amyotrophic lateral sclerosis.

Liebl MP, Windschmitt J, Besemer AS, Schäfer AK, Reber H, Behl C, Clement AM.

Sci Rep. 2015 Feb 26;5:8585. doi: 10.1038/srep08585.


RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy.

Spang N, Feldmann A, Huesmann H, Bekbulat F, Schmitt V, Hiebel C, Koziollek-Drechsler I, Clement AM, Moosmann B, Jung J, Behrends C, Dikic I, Kern A, Behl C.

Autophagy. 2014;10(12):2297-309. doi: 10.4161/15548627.2014.994359.


The first virtual cranial endocast of a lungfish (sarcopterygii: dipnoi).

Clement AM, Ahlberg PE.

PLoS One. 2014 Nov 26;9(11):e113898. doi: 10.1371/journal.pone.0113898. eCollection 2014.


Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial.

Rodger MA, Hague WM, Kingdom J, Kahn SR, Karovitch A, Sermer M, Clement AM, Coat S, Chan WS, Said J, Rey E, Robinson S, Khurana R, Demers C, Kovacs MJ, Solymoss S, Hinshaw K, Dwyer J, Smith G, McDonald S, Newstead-Angel J, McLeod A, Khandelwal M, Silver RM, Le Gal G, Greer IA, Keely E, Rosene-Montella K, Walker M, Wells PS; TIPPS Investigators.

Lancet. 2014 Nov 8;384(9955):1673-83. doi: 10.1016/S0140-6736(14)60793-5. Epub 2014 Jul 24.


Dimerization of visinin-like protein 1 is regulated by oxidative stress and calcium and is a pathological hallmark of amyotrophic lateral sclerosis.

Liebl MP, Kaya AM, Tenzer S, Mittenzwei R, Koziollek-Drechsler I, Schild H, Moosmann B, Behl C, Clement AM.

Free Radic Biol Med. 2014 Jul;72:41-54. doi: 10.1016/j.freeradbiomed.2014.04.008. Epub 2014 Apr 15.


Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization.

Weichert A, Besemer AS, Liebl M, Hellmann N, Koziollek-Drechsler I, Ip P, Decker H, Robertson J, Chakrabartty A, Behl C, Clement AM.

Neurobiol Dis. 2014 Feb;62:479-88. doi: 10.1016/j.nbd.2013.10.027. Epub 2013 Nov 4.


Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates.

Korac J, Schaeffer V, Kovacevic I, Clement AM, Jungblut B, Behl C, Terzic J, Dikic I.

J Cell Sci. 2013 Jan 15;126(Pt 2):580-92. doi: 10.1242/jcs.114926. Epub 2012 Nov 23.


Two in one against motor neuron degeneration: tackling oxidative stress and inflammation with a sulfasalazine derivative.

Clement AM.

J Neurochem. 2012 Sep;122(5):869-71. doi: 10.1111/j.1471-4159.2012.07843.x. No abstract available.


Neuroendocrine predictors of emotional and behavioral adjustment in boys: longitudinal follow-up of a community sample.

Tyrka AR, Lee JK, Graber JA, Clement AM, Kelly MM, DeRose L, Warren MP, Brooks-Gunn J.

Psychoneuroendocrinology. 2012 Dec;37(12):2042-6. doi: 10.1016/j.psyneuen.2012.04.004. Epub 2012 May 9.


Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells.

Witte I, Altenhöfer S, Wilgenbus P, Amort J, Clement AM, Pautz A, Li H, Förstermann U, Horke S.

Cell Death Dis. 2011 Jan 13;2:e112. doi: 10.1038/cddis.2010.91.


BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.

Gamerdinger M, Kaya AM, Wolfrum U, Clement AM, Behl C.

EMBO Rep. 2011 Feb;12(2):149-56. doi: 10.1038/embor.2010.203. Epub 2011 Jan 21.


One enzyme, two functions: PON2 prevents mitochondrial superoxide formation and apoptosis independent from its lactonase activity.

Altenhöfer S, Witte I, Teiber JF, Wilgenbus P, Pautz A, Li H, Daiber A, Witan H, Clement AM, Förstermann U, Horke S.

J Biol Chem. 2010 Aug 6;285(32):24398-403. doi: 10.1074/jbc.M110.118604. Epub 2010 Jun 8.


Air-breathing adaptation in a marine Devonian lungfish.

Clement AM, Long JA.

Biol Lett. 2010 Aug 23;6(4):509-12. doi: 10.1098/rsbl.2009.1033. Epub 2010 Feb 10.


HSF1-controlled and age-associated chaperone capacity in neurons and muscle cells of C. elegans.

Kern A, Ackermann B, Clement AM, Duerk H, Behl C.

PLoS One. 2010 Jan 5;5(1):e8568. doi: 10.1371/journal.pone.0008568.


Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1.

Witan H, Gorlovoy P, Kaya AM, Koziollek-Drechsler I, Neumann H, Behl C, Clement AM.

Neurobiol Dis. 2009 Nov;36(2):331-42. doi: 10.1016/j.nbd.2009.07.024. Epub 2009 Aug 4.


Heterodimer formation of wild-type and amyotrophic lateral sclerosis-causing mutant Cu/Zn-superoxide dismutase induces toxicity independent of protein aggregation.

Witan H, Kern A, Koziollek-Drechsler I, Wade R, Behl C, Clement AM.

Hum Mol Genet. 2008 May 15;17(10):1373-85. doi: 10.1093/hmg/ddn025. Epub 2008 Jan 22.


Long-term dalteparin in pregnancy not associated with a decrease in bone mineral density: substudy of a randomized controlled trial.

Rodger MA, Kahn SR, Cranney A, Hodsman A, Kovacs MJ, Clement AM, Lazo-Langner A, Hague WM; TIPPS investigators.

J Thromb Haemost. 2007 Aug;5(8):1600-6.


The effect of dalteparin on coagulation activation during pregnancy in women with thrombophilia. A randomized trial.

Abou-Nassar K, Kovacs MJ, Kahn SR, Wells P, Doucette S, Ramsay T, Clement AM, Khurana R, Mackinnon K, Blostein M, Solymoss S, Kingdom J, Sermer M, Rey E, Rodger M; TIPPS investigators.

Thromb Haemost. 2007 Jul;98(1):163-71.


The bedside investigation of pulmonary embolism diagnosis study: a double-blind randomized controlled trial comparing combinations of 3 bedside tests vs ventilation-perfusion scan for the initial investigation of suspected pulmonary embolism.

Rodger MA, Bredeson CN, Jones G, Rasuli P, Raymond F, Clement AM, Karovitch A, Brunette H, Makropoulos D, Reardon M, Stiell I, Nair R, Wells PS.

Arch Intern Med. 2006 Jan 23;166(2):181-7.


Differential promotion of glutamate transporter expression and function by glucocorticoids in astrocytes from various brain regions.

Zschocke J, Bayatti N, Clement AM, Witan H, Figiel M, Engele J, Behl C.

J Biol Chem. 2005 Oct 14;280(41):34924-32. Epub 2005 Aug 3.


Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.

Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH Jr, Julien JP, Goldstein LS, Cleveland DW.

Science. 2003 Oct 3;302(5642):113-7. Erratum in: Science. 2003 Oct 24;302(5645):568.


Chondroitin sulfate E promotes neurite outgrowth of rat embryonic day 18 hippocampal neurons.

Clement AM, Sugahara K, Faissner A.

Neurosci Lett. 1999 Jul 16;269(3):125-8.


The DSD-1 carbohydrate epitope depends on sulfation, correlates with chondroitin sulfate D motifs, and is sufficient to promote neurite outgrowth.

Clement AM, Nadanaka S, Masayama K, Mandl C, Sugahara K, Faissner A.

J Biol Chem. 1998 Oct 23;273(43):28444-53.


Coordination of occupational therapy and the nursing service in patient treatment.


Am J Occup Ther. 1955 Sep-Oct;9(5 Part II):250-1. No abstract available.


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