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Items: 22


Drosophila Dyrk2 plays a role in the development of the visual system.

Luebbering N, Charlton-Perkins M, Kumar JP, Lochead PA, Rollmann SM, Cook T, Cleghon V.

PLoS One. 2013 Oct 11;8(10):e76775. doi: 10.1371/journal.pone.0076775. eCollection 2013. Erratum in: PLoS One. 2014;9(3):e92344. Lochead, Pamela A [added].


Deep evolutionary conservation of an intramolecular protein kinase activation mechanism.

Han J, Miranda-Saavedra D, Luebbering N, Singh A, Sibbet G, Ferguson MA, Cleghon V.

PLoS One. 2012;7(1):e29702. doi: 10.1371/journal.pone.0029702. Epub 2012 Jan 3.


Characterization of a domain that transiently converts class 2 DYRKs into intramolecular tyrosine kinases.

Kinstrie R, Luebbering N, Miranda-Saavedra D, Sibbet G, Han J, Lochhead PA, Cleghon V.

Sci Signal. 2010 Mar 2;3(111):ra16. doi: 10.1126/scisignal.2000579.


Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein.

Day JP, Cleghon V, Houslay MD, Davies SA.

Biochem J. 2008 Sep 15;414(3):363-74. doi: 10.1042/BJ20080560.


A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation.

Lochhead PA, Kinstrie R, Sibbet G, Rawjee T, Morrice N, Cleghon V.

Mol Cell. 2006 Nov 17;24(4):627-33.


dDYRK2 and Minibrain interact with the chromatin remodelling factors SNR1 and TRX.

Kinstrie R, Lochhead PA, Sibbet G, Morrice N, Cleghon V.

Biochem J. 2006 Aug 15;398(1):45-54.


Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.

Lochhead PA, Sibbet G, Morrice N, Cleghon V.

Cell. 2005 Jun 17;121(6):925-36.


dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

Lochhead PA, Sibbet G, Kinstrie R, Cleghon T, Rylatt M, Morrison DK, Cleghon V.

Biochem J. 2003 Sep 1;374(Pt 2):381-91.


Protein kinases and phosphatases in the Drosophila genome.

Morrison DK, Murakami MS, Cleghon V.

J Cell Biol. 2000 Jul 24;150(2):F57-62. Review. No abstract available.


Synergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso receptor tyrosine kinase.

Gayko U, Cleghon V, Copeland T, Morrison DK, Perrimon N.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):523-8.


Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

Cleghon V, Feldmann P, Ghiglione C, Copeland TD, Perrimon N, Hughes DA, Morrison DK.

Mol Cell. 1998 Dec;2(6):719-27.


Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner.

Cleghon V, Morrison DK.

J Biol Chem. 1994 Jul 1;269(26):17749-55.


Phosphorylation of the adenovirus DNA-binding protein and epitope mapping of monoclonal antibodies against it.

Cleghon V, Piderit A, Brough DE, Klessig DF.

Virology. 1993 Dec;197(2):564-75.


Isolation and characterization of a viable adenovirus mutant defective in nuclear transport of the DNA-binding protein.

Cleghon V, Voelkerding K, Morin N, Delsert C, Klessig DF.

J Virol. 1989 May;63(5):2289-99.


Association of the adenovirus DNA-binding protein with RNA both in vitro and in vivo.

Cleghon VG, Klessig DF.

Proc Natl Acad Sci U S A. 1986 Dec;83(23):8947-51.

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