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Treatment Patterns with Disease-Modifying Antirheumatic Drugs in U.S. Veterans with Newly Diagnosed Rheumatoid Arthritis, Psoriatic Arthritis, or Ankylosing Spondylitis.

Walsh JA, Pei S, Penmetsa GK, Sauer BC, Patil V, Walker JH, Clewell J, Douglas KM, Clegg DO, Cannon GW, Halwani A.

J Manag Care Spec Pharm. 2019 Nov;25(11):1218-1228. doi: 10.18553/jmcp.2019.25.11.1218.


Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.

Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE, Thomson JA.

Lab Invest. 2019 Oct;99(10):1547-1560. doi: 10.1038/s41374-019-0264-3. Epub 2019 May 17.


Identification of Axial Spondyloarthritis Patients in a Large Dataset: The Development and Validation of Novel Methods.

Walsh JA, Pei S, Penmetsa G, Hansen JL, Cannon GW, Clegg DO, Sauer BC.

J Rheumatol. 2019 Mar 15. pii: jrheum.181005. doi: 10.3899/jrheum.181005. [Epub ahead of print]


Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9.

Foltz LP, Howden SE, Thomson JA, Clegg DO.

Int J Mol Sci. 2018 Dec 19;19(12). pii: E4127. doi: 10.3390/ijms19124127.


The Physician Global Assessment and Body Surface Area composite tool is a simple alternative to the Psoriasis Area and Severity Index for assessment of psoriasis: post hoc analysis from PRISTINE and PRESTA.

Walsh JA, Jones H, Mallbris L, Duffin KC, Krueger GG, Clegg DO, Szumski A.

Psoriasis (Auckl). 2018 Oct 8;8:65-74. doi: 10.2147/PTT.S169333. eCollection 2018.


Patient-derived induced pluripotent stem cells for modelling genetic retinal dystrophies.

Foltz LP, Clegg DO.

Prog Retin Eye Res. 2019 Jan;68:54-66. doi: 10.1016/j.preteyeres.2018.09.002. Epub 2018 Sep 11. Review.


Cohort identification of axial spondyloarthritis in a large healthcare dataset: current and future methods.

Walsh JA, Pei S, Penmetsa GK, Leng J, Cannon GW, Clegg DO, Sauer BC.

BMC Musculoskelet Disord. 2018 Sep 5;19(1):317. doi: 10.1186/s12891-018-2211-7.


An initiative using informatics to facilitate clinical research planning and recruitment in the VA health care system.

Velarde KE, Romesser JM, Johnson MR, Clegg DO, Efimova O, Oostema SJ, Scehnet JS, DuVall SL, Huang GD.

Contemp Clin Trials Commun. 2018 Jul 10;11:107-112. doi: 10.1016/j.conctc.2018.07.001. eCollection 2018 Sep.


Remifentanil Stability.

Bevans-Warren TS, Clegg DO Jr, Sakata DJ, Reilly CA.

Anesth Analg. 2018 Sep;127(3):e51-e52. doi: 10.1213/ANE.0000000000003600. No abstract available.


A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.

Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, Humayun MS.

Sci Transl Med. 2018 Apr 4;10(435). pii: eaao4097. doi: 10.1126/scitranslmed.aao4097.


Use of Disease-modifying Antirheumatic Drugs for Inflammatory Arthritis in US Veterans: Effect of Specialty Care and Geographic Distance.

Walsh JA, Pei S, Burningham Z, Penmetsa G, Cannon GW, Clegg DO, Sauer BC.

J Rheumatol. 2018 Mar;45(3):430-436. doi: 10.3899/jrheum.170554. Epub 2017 Nov 15.


Adipose Stem Cells Incorporated in Fibrin Clot Modulate Expression of Growth Factors.

Siegel KR, Clevenger TN, Clegg DO, Proctor DA, Proctor CS.

Arthroscopy. 2018 Feb;34(2):581-591. doi: 10.1016/j.arthro.2017.08.250.


Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models.

Lin TC, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB.

Stem Cells Int. 2017;2017:9428176. doi: 10.1155/2017/9428176. Epub 2017 Aug 27. Review.


HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells.

Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi LA, Clegg DO, Turtle C, Russell DW.

Nat Biotechnol. 2017 Aug;35(8):765-772. doi: 10.1038/nbt.3860. Epub 2017 May 15.


Identifying Axial Spondyloarthritis in Electronic Medical Records of US Veterans.

Walsh JA, Shao Y, Leng J, He T, Teng CC, Redd D, Treitler Zeng Q, Burningham Z, Clegg DO, Sauer BC.

Arthritis Care Res (Hoboken). 2017 Sep;69(9):1414-1420. doi: 10.1002/acr.23140. Epub 2017 Aug 8.


Light-Patterned RNA Interference of 3D-Cultured Human Embryonic Stem Cells.

Huang X, Hu Q, Lai Y, Morales DP, Clegg DO, Reich NO.

Adv Mater. 2016 Dec;28(48):10732-10737. doi: 10.1002/adma.201603318. Epub 2016 Oct 27.


Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells.

Clevenger TN, Luna G, Boctor D, Fisher SK, Clegg DO.

J Tissue Eng. 2016 Sep 23;7:2041731416670482. eCollection 2016 Jan-Dec.


Strategies for bioengineered scaffolds that support adipose stem cells in regenerative therapies.

Clevenger TN, Luna G, Fisher SK, Clegg DO.

Regen Med. 2016 Sep;11(6):589-99. doi: 10.2217/rme-2016-0064. Epub 2016 Aug 3. Review.


Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs.

Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR, Humayun MS.

Graefes Arch Clin Exp Ophthalmol. 2016 Aug;254(8):1553-1565. doi: 10.1007/s00417-016-3386-y. Epub 2016 Jun 22.


Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats.

Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR, Humayun MS.

Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2877-87. doi: 10.1167/iovs.16-19238.


Regenerating Perfection.

Clegg DO.

J Ocul Pharmacol Ther. 2016 Jun;32(5):237. doi: 10.1089/jop.2016.29013.doclegg. Epub 2016 May 23. No abstract available.


Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods.

Leach LL, Croze RH, Hu Q, Nadar VP, Clevenger TN, Pennington BO, Gamm DM, Clegg DO.

J Ocul Pharmacol Ther. 2016 Jun;32(5):317-30. doi: 10.1089/jop.2016.0022. Epub 2016 May 16.


An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results.

Brant Fernandes RA, Koss MJ, Falabella P, Stefanini FR, Maia M, Diniz B, Ribeiro R, Hu Y, Hinton D, Clegg DO, Chader G, Humayun MS.

Ophthalmic Surg Lasers Imaging Retina. 2016 Apr 1;47(4):342-51. doi: 10.3928/23258160-20160324-07.


Vitronectin-Based, Biomimetic Encapsulating Hydrogel Scaffolds Support Adipogenesis of Adipose Stem Cells.

Clevenger TN, Hinman CR, Ashley Rubin RK, Smither K, Burke DJ, Hawker CJ, Messina D, Van Epps D, Clegg DO.

Tissue Eng Part A. 2016 Apr;22(7-8):597-609. doi: 10.1089/ten.TEA.2015.0550. Epub 2016 Mar 31.


Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration.

Pennington BO, Clegg DO.

J Ocul Pharmacol Ther. 2016 Jun;32(5):261-71. doi: 10.1089/jop.2015.0153. Epub 2016 Feb 18. Review.


Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells.

Zhao T, Zhang ZN, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg DO, Yang YG, Zhang K, Friedlander M, Xu Y.

Cell Stem Cell. 2015 Sep 3;17(3):353-9. doi: 10.1016/j.stem.2015.07.021. Epub 2015 Aug 20.


Stem cell based therapies for age-related macular degeneration: The promises and the challenges.

Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rowland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS.

Prog Retin Eye Res. 2015 Sep;48:1-39. doi: 10.1016/j.preteyeres.2015.06.004. Epub 2015 Jun 23. Review.


Light-activated RNA interference in human embryonic stem cells.

Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO.

Biomaterials. 2015 Sep;63:70-9. doi: 10.1016/j.biomaterials.2015.06.006. Epub 2015 Jun 10.


Cellular models and therapies for age-related macular degeneration.

Forest DL, Johnson LV, Clegg DO.

Dis Model Mech. 2015 May;8(5):421-7. doi: 10.1242/dmm.017236. Review.


Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease.

Leach LL, Clegg DO.

Stem Cells. 2015 Aug;33(8):2363-73. doi: 10.1002/stem.2010. Epub 2015 Apr 21. Review.


Mortality in American Veterans with the HLA-B27 gene.

Walsh JA, Zhou X, Clegg DO, Teng C, Cannon GW, Sauer B.

J Rheumatol. 2015 Apr;42(4):638-44. doi: 10.3899/jrheum.140675. Epub 2015 Feb 15.


Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells.

Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.

Invest Ophthalmol Vis Sci. 2015 Jan 20;56(2):1002-13. doi: 10.1167/iovs.14-15835.


Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate.

Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST.

Stem Cells Transl Med. 2015 Feb;4(2):165-77. doi: 10.5966/sctm.2014-0179. Epub 2015 Jan 15.


Interactive Hangman teaches amino acid structures and abbreviations.

Pennington BO, Sears D, Clegg DO.

Biochem Mol Biol Educ. 2014 Nov-Dec;42(6):495-500. doi: 10.1002/bmb.20826. Epub 2014 Oct 25.


Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins.

Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO.

Stem Cells Transl Med. 2014 Dec;3(12):1526-34. doi: 10.5966/sctm.2014-0038. Epub 2014 Oct 8.


The concept of axial spondyloarthritis: joint statement of the spondyloarthritis research and treatment network and the Assessment of SpondyloArthritis international Society in response to the US Food and Drug Administration's comments and concerns.

Deodhar A, Reveille JD, van den Bosch F, Braun J, Burgos-Vargas R, Caplan L, Clegg DO, Colbert RA, Gensler LS, van der Heijde D, van der Horst-Bruinsma IE, Inman RD, Maksymowych WP, Mease PJ, Raychaudhuri S, Reimold A, Rudwaleit M, Sieper J, Weisman MH, Landewé RB.

Arthritis Rheumatol. 2014 Oct;66(10):2649-56. doi: 10.1002/art.38776. No abstract available.


ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium.

Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO.

Stem Cells Transl Med. 2014 Sep;3(9):1066-78. doi: 10.5966/sctm.2014-0079. Epub 2014 Jul 28.


Rapidly Fatal Internal Carotid Artery Mycotic Aneurysm Rupture in a Rheumatoid Patient Taking a TNF-α Inhibitor: Case Report and Literature Review.

Bowers CA, Saad D, Clegg DO, Ng P, Clayton F, Haydoura S, Schmidt RH.

J Neurol Surg A Cent Eur Neurosurg. 2015 May;76(3):249-54. doi: 10.1055/s-0034-1372435. Epub 2014 Jul 21.


Work productivity loss and fatigue in psoriatic arthritis.

Walsh JA, McFadden ML, Morgan MD, Sawitzke AD, Duffin KC, Krueger GG, Clegg DO.

J Rheumatol. 2014 Aug;41(8):1670-4. doi: 10.3899/jrheum.140259. Epub 2014 Jul 15.


New population-based reference values for spinal mobility measures based on the 2009-2010 National Health and Nutrition Examination Survey.

Assassi S, Weisman MH, Lee M, Savage L, Diekman L, Graham TA, Rahbar MH, Schall JI, Gensler LS, Deodhar AA, Clegg DO, Colbert RA, Reveille JD.

Arthritis Rheumatol. 2014 Sep;66(9):2628-37. doi: 10.1002/art.38692.


Differentiation of pluripotent stem cells into retinal pigmented epithelium.

Croze RH, Clegg DO.

Dev Ophthalmol. 2014;53:81-96. doi: 10.1159/000357361. Epub 2014 Apr 10. Review.


Product of the Physician Global Assessment and body surface area: a simple static measure of psoriasis severity in a longitudinal cohort.

Walsh JA, McFadden M, Woodcock J, Clegg DO, Helliwell P, Dommasch E, Gelfand JM, Krueger GG, Duffin KC.

J Am Acad Dermatol. 2013 Dec;69(6):931-7. doi: 10.1016/j.jaad.2013.07.040. Epub 2013 Sep 17.


Ankylosing spondylitis clinical registries: principles, practices and possibilities.

Caplan L, Clegg DO, Inman RD.

Am J Med Sci. 2013 Jun;345(6):437-9.


Comparing nebulized water versus saline after laryngeal desiccation challenge in Sjögren's Syndrome.

Tanner K, Roy N, Merrill RM, Kendall K, Miller KL, Clegg DO, Heller A, Houtz DR, Elstad M.

Laryngoscope. 2013 Nov;123(11):2787-92. doi: 10.1002/lary.24148. Epub 2013 May 14.


Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium.

Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO.

Stem Cells Transl Med. 2013 May;2(5):384-93. doi: 10.5966/sctm.2012-0163. Epub 2013 Apr 18.


Limitations in screening instruments for psoriatic arthritis: a comparison of instruments in patients with psoriasis.

Walsh JA, Callis Duffin K, Krueger GG, Clegg DO.

J Rheumatol. 2013 Mar;40(3):287-93. doi: 10.3899/jrheum.120836. Epub 2013 Feb 1.


Lower frequency of obstructive sleep apnea in spondyloarthritis patients taking TNF-inhibitors.

Walsh JA, Duffin KC, Crim J, Clegg DO.

J Clin Sleep Med. 2012 Dec 15;8(6):643-8. doi: 10.5664/jcsm.2254.


New paradigm for patient-reported outcomes assessment in foot & ankle research: computerized adaptive testing.

Hung M, Nickisch F, Beals TC, Greene T, Clegg DO, Saltzman CL.

Foot Ankle Int. 2012 Aug;33(8):621-6.


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