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Items: 1 to 50 of 185

1.

A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.

Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, Humayun MS.

Sci Transl Med. 2018 Apr 4;10(435). pii: eaao4097. doi: 10.1126/scitranslmed.aao4097.

PMID:
29618560
2.
3.

Use of Disease-modifying Antirheumatic Drugs for Inflammatory Arthritis in US Veterans: Effect of Specialty Care and Geographic Distance.

Walsh JA, Pei S, Burningham Z, Penmetsa G, Cannon GW, Clegg DO, Sauer BC.

J Rheumatol. 2018 Mar;45(3):430-436. doi: 10.3899/jrheum.170554. Epub 2017 Nov 15.

PMID:
29142040
4.

Adipose Stem Cells Incorporated in Fibrin Clot Modulate Expression of Growth Factors.

Siegel KR, Clevenger TN, Clegg DO, Proctor DA, Proctor CS.

Arthroscopy. 2018 Feb;34(2):581-591. doi: 10.1016/j.arthro.2017.08.250.

PMID:
29100775
5.

Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models.

Lin TC, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB.

Stem Cells Int. 2017;2017:9428176. doi: 10.1155/2017/9428176. Epub 2017 Aug 27. Review.

6.

HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells.

Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi LA, Clegg DO, Turtle C, Russell DW.

Nat Biotechnol. 2017 Aug;35(8):765-772. doi: 10.1038/nbt.3860. Epub 2017 May 15.

7.
8.

Identifying Axial Spondyloarthritis in Electronic Medical Records of US Veterans.

Walsh JA, Shao Y, Leng J, He T, Teng CC, Redd D, Treitler Zeng Q, Burningham Z, Clegg DO, Sauer BC.

Arthritis Care Res (Hoboken). 2017 Sep;69(9):1414-1420. doi: 10.1002/acr.23140. Epub 2017 Aug 8.

PMID:
27813310
9.

Light-Patterned RNA Interference of 3D-Cultured Human Embryonic Stem Cells.

Huang X, Hu Q, Lai Y, Morales DP, Clegg DO, Reich NO.

Adv Mater. 2016 Dec;28(48):10732-10737. doi: 10.1002/adma.201603318. Epub 2016 Oct 27.

PMID:
27787919
10.

Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells.

Clevenger TN, Luna G, Boctor D, Fisher SK, Clegg DO.

J Tissue Eng. 2016 Sep 23;7:2041731416670482. eCollection 2016 Jan-Dec.

11.

Strategies for bioengineered scaffolds that support adipose stem cells in regenerative therapies.

Clevenger TN, Luna G, Fisher SK, Clegg DO.

Regen Med. 2016 Sep;11(6):589-99. doi: 10.2217/rme-2016-0064. Epub 2016 Aug 3. Review.

12.

Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs.

Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR, Humayun MS.

Graefes Arch Clin Exp Ophthalmol. 2016 Aug;254(8):1553-65. doi: 10.1007/s00417-016-3386-y. Epub 2016 Jun 22.

PMID:
27335025
13.

Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats.

Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR, Humayun MS.

Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2877-87. doi: 10.1167/iovs.16-19238.

PMID:
27233037
14.

Regenerating Perfection.

Clegg DO.

J Ocul Pharmacol Ther. 2016 Jun;32(5):237. doi: 10.1089/jop.2016.29013.doclegg. Epub 2016 May 23. No abstract available.

PMID:
27214692
15.

Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods.

Leach LL, Croze RH, Hu Q, Nadar VP, Clevenger TN, Pennington BO, Gamm DM, Clegg DO.

J Ocul Pharmacol Ther. 2016 Jun;32(5):317-30. doi: 10.1089/jop.2016.0022. Epub 2016 May 16.

16.

An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results.

Brant Fernandes RA, Koss MJ, Falabella P, Stefanini FR, Maia M, Diniz B, Ribeiro R, Hu Y, Hinton D, Clegg DO, Chader G, Humayun MS.

Ophthalmic Surg Lasers Imaging Retina. 2016 Apr 1;47(4):342-51. doi: 10.3928/23258160-20160324-07.

PMID:
27065374
17.

Vitronectin-Based, Biomimetic Encapsulating Hydrogel Scaffolds Support Adipogenesis of Adipose Stem Cells.

Clevenger TN, Hinman CR, Ashley Rubin RK, Smither K, Burke DJ, Hawker CJ, Messina D, Van Epps D, Clegg DO.

Tissue Eng Part A. 2016 Apr;22(7-8):597-609. doi: 10.1089/ten.TEA.2015.0550. Epub 2016 Mar 31.

18.

Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration.

Pennington BO, Clegg DO.

J Ocul Pharmacol Ther. 2016 Jun;32(5):261-71. doi: 10.1089/jop.2015.0153. Epub 2016 Feb 18. Review.

PMID:
26889704
19.

Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells.

Zhao T, Zhang ZN, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg DO, Yang YG, Zhang K, Friedlander M, Xu Y.

Cell Stem Cell. 2015 Sep 3;17(3):353-9. doi: 10.1016/j.stem.2015.07.021. Epub 2015 Aug 20.

20.

Stem cell based therapies for age-related macular degeneration: The promises and the challenges.

Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rowland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS.

Prog Retin Eye Res. 2015 Sep;48:1-39. doi: 10.1016/j.preteyeres.2015.06.004. Epub 2015 Jun 23. Review.

PMID:
26113213
21.

Light-activated RNA interference in human embryonic stem cells.

Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO.

Biomaterials. 2015 Sep;63:70-9. doi: 10.1016/j.biomaterials.2015.06.006. Epub 2015 Jun 10.

PMID:
26086448
22.

Cellular models and therapies for age-related macular degeneration.

Forest DL, Johnson LV, Clegg DO.

Dis Model Mech. 2015 May;8(5):421-7. doi: 10.1242/dmm.017236. Review.

23.

Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease.

Leach LL, Clegg DO.

Stem Cells. 2015 Aug;33(8):2363-73. doi: 10.1002/stem.2010. Epub 2015 Apr 21. Review.

24.

Mortality in American Veterans with the HLA-B27 gene.

Walsh JA, Zhou X, Clegg DO, Teng C, Cannon GW, Sauer B.

J Rheumatol. 2015 Apr;42(4):638-44. doi: 10.3899/jrheum.140675. Epub 2015 Feb 15.

PMID:
25684766
25.

Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells.

Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.

Invest Ophthalmol Vis Sci. 2015 Jan 20;56(2):1002-13. doi: 10.1167/iovs.14-15835.

26.

Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate.

Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST.

Stem Cells Transl Med. 2015 Feb;4(2):165-77. doi: 10.5966/sctm.2014-0179. Epub 2015 Jan 15.

27.

Interactive Hangman teaches amino acid structures and abbreviations.

Pennington BO, Sears D, Clegg DO.

Biochem Mol Biol Educ. 2014 Nov-Dec;42(6):495-500. doi: 10.1002/bmb.20826. Epub 2014 Oct 25.

28.

Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins.

Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO.

Stem Cells Transl Med. 2014 Dec;3(12):1526-34. doi: 10.5966/sctm.2014-0038. Epub 2014 Oct 8.

29.

The concept of axial spondyloarthritis: joint statement of the spondyloarthritis research and treatment network and the Assessment of SpondyloArthritis international Society in response to the US Food and Drug Administration's comments and concerns.

Deodhar A, Reveille JD, van den Bosch F, Braun J, Burgos-Vargas R, Caplan L, Clegg DO, Colbert RA, Gensler LS, van der Heijde D, van der Horst-Bruinsma IE, Inman RD, Maksymowych WP, Mease PJ, Raychaudhuri S, Reimold A, Rudwaleit M, Sieper J, Weisman MH, Landewé RB.

Arthritis Rheumatol. 2014 Oct;66(10):2649-56. doi: 10.1002/art.38776. No abstract available.

30.

ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium.

Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO.

Stem Cells Transl Med. 2014 Sep;3(9):1066-78. doi: 10.5966/sctm.2014-0079. Epub 2014 Jul 28.

31.

Rapidly Fatal Internal Carotid Artery Mycotic Aneurysm Rupture in a Rheumatoid Patient Taking a TNF-α Inhibitor: Case Report and Literature Review.

Bowers CA, Saad D, Clegg DO, Ng P, Clayton F, Haydoura S, Schmidt RH.

J Neurol Surg A Cent Eur Neurosurg. 2015 May;76(3):249-54. doi: 10.1055/s-0034-1372435. Epub 2014 Jul 21.

PMID:
25045858
32.

Work productivity loss and fatigue in psoriatic arthritis.

Walsh JA, McFadden ML, Morgan MD, Sawitzke AD, Duffin KC, Krueger GG, Clegg DO.

J Rheumatol. 2014 Aug;41(8):1670-4. doi: 10.3899/jrheum.140259. Epub 2014 Jul 15.

PMID:
25028377
33.

New population-based reference values for spinal mobility measures based on the 2009-2010 National Health and Nutrition Examination Survey.

Assassi S, Weisman MH, Lee M, Savage L, Diekman L, Graham TA, Rahbar MH, Schall JI, Gensler LS, Deodhar AA, Clegg DO, Colbert RA, Reveille JD.

Arthritis Rheumatol. 2014 Sep;66(9):2628-37. doi: 10.1002/art.38692.

34.

Differentiation of pluripotent stem cells into retinal pigmented epithelium.

Croze RH, Clegg DO.

Dev Ophthalmol. 2014;53:81-96. doi: 10.1159/000357361. Epub 2014 Apr 10. Review.

PMID:
24732763
35.

Product of the Physician Global Assessment and body surface area: a simple static measure of psoriasis severity in a longitudinal cohort.

Walsh JA, McFadden M, Woodcock J, Clegg DO, Helliwell P, Dommasch E, Gelfand JM, Krueger GG, Duffin KC.

J Am Acad Dermatol. 2013 Dec;69(6):931-7. doi: 10.1016/j.jaad.2013.07.040. Epub 2013 Sep 17.

PMID:
24054760
36.

Ankylosing spondylitis clinical registries: principles, practices and possibilities.

Caplan L, Clegg DO, Inman RD.

Am J Med Sci. 2013 Jun;345(6):437-9.

PMID:
23841118
37.

Comparing nebulized water versus saline after laryngeal desiccation challenge in Sjögren's Syndrome.

Tanner K, Roy N, Merrill RM, Kendall K, Miller KL, Clegg DO, Heller A, Houtz DR, Elstad M.

Laryngoscope. 2013 Nov;123(11):2787-92. doi: 10.1002/lary.24148. Epub 2013 May 14.

PMID:
23674107
38.

Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium.

Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO.

Stem Cells Transl Med. 2013 May;2(5):384-93. doi: 10.5966/sctm.2012-0163. Epub 2013 Apr 18.

39.

Limitations in screening instruments for psoriatic arthritis: a comparison of instruments in patients with psoriasis.

Walsh JA, Callis Duffin K, Krueger GG, Clegg DO.

J Rheumatol. 2013 Mar;40(3):287-93. doi: 10.3899/jrheum.120836. Epub 2013 Feb 1.

PMID:
23378465
40.

Lower frequency of obstructive sleep apnea in spondyloarthritis patients taking TNF-inhibitors.

Walsh JA, Duffin KC, Crim J, Clegg DO.

J Clin Sleep Med. 2012 Dec 15;8(6):643-8. doi: 10.5664/jcsm.2254.

41.

New paradigm for patient-reported outcomes assessment in foot & ankle research: computerized adaptive testing.

Hung M, Nickisch F, Beals TC, Greene T, Clegg DO, Saltzman CL.

Foot Ankle Int. 2012 Aug;33(8):621-6.

PMID:
22995227
42.

Combined structural and synovial assessment for improved ultrasound discrimination of rheumatoid, osteoarthritic, and normal joints: a pilot study.

Kunkel GA, Cannon GW, Clegg DO.

Open Rheumatol J. 2012;6:199-206. doi: 10.2174/1874312901206010199. Epub 2012 Aug 9.

43.

A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer.

Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai YC, Hikita ST, Johnson LV, Clegg DO, Thomas BB, Humayun MS.

Ophthalmic Res. 2012;48(4):186-91. doi: 10.1159/000338749. Epub 2012 Aug 3.

44.

A lower extremity physical function computerized adaptive testing instrument for orthopaedic patients.

Hung M, Clegg DO, Greene T, Weir C, Saltzman CL.

Foot Ankle Int. 2012 Apr;33(4):326-35. doi: 10.3113/FAI.2012.0326.

PMID:
22735205
45.

Critical appraisal of the guidelines for the management of ankylosing spondylitis: disease-modifying antirheumatic drugs.

Soriano ER, Clegg DO, Lisse JR.

Am J Med Sci. 2012 May;343(5):357-9. doi: 10.1097/MAJ.0b013e3182513f9c. Review.

PMID:
22543537
46.

Management of ankylosing spondylitis: what is known; what is not known?

Deodhar A, Clegg DO.

Am J Med Sci. 2012 May;343(5):343-4. doi: 10.1097/MAJ.0b013e31825141bf. No abstract available.

PMID:
22543533
47.

Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins.

Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO.

J Tissue Eng Regen Med. 2013 Aug;7(8):642-53. doi: 10.1002/term.1458. Epub 2012 Apr 18.

PMID:
22514096
48.

OARSI-OMERACT initiative: defining thresholds for symptomatic severity and structural changes in disease modifying osteoarthritis drug (DMOAD) clinical trials.

Manno RL, Bingham CO 3rd, Paternotte S, Gossec L, Halhol H, Giacovelli G, Rovati L, Mazzuca SA, Clegg DO, Shi H, Tajana Messi E, Lanzarotti A, Dougados M.

Osteoarthritis Cartilage. 2012 Feb;20(2):93-101. doi: 10.1016/j.joca.2011.11.013. Epub 2011 Nov 28.

49.

OARSI/OMERACT initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. An OMERACT 10 Special Interest Group.

Gossec L, Paternotte S, Bingham CO 3rd, Clegg DO, Coste P, Conaghan PG, Davis AM, Giacovelli G, Gunther KP, Hawker G, Hochberg MC, Jordan JM, Katz JN, Kloppenburg M, Lanzarotti A, Lim K, Lohmander LS, Mahomed NN, Maillefert JF, Manno RL, March LM, Mazzuca SA, Pavelka K, Punzi L, Roos EM, Rovati LC, Shi H, Singh JA, Suarez-Almazor ME, Tajana-Messi E, Dougados M; OARSI-OMERACT Task Force Total Articular Replacement as Outcome Measure in OA.

J Rheumatol. 2011 Aug;38(8):1765-9. doi: 10.3899/jrheum.110403.

50.

Pluripotent human stem cells for the treatment of retinal disease.

Rowland TJ, Buchholz DE, Clegg DO.

J Cell Physiol. 2012 Feb;227(2):457-66. doi: 10.1002/jcp.22814. Review.

PMID:
21520078

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