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BACL is a novel brain-associated, non-NKC-encoded mammalian C-type lectin-like receptor of the CLEC2 family.
Lysenko O, Schulte D, Mittelbronn M, Steinle A. Lysenko O, et al. PLoS One. 2013 Jun 11;8(6):e65345. doi: 10.1371/journal.pone.0065345. Print 2013. PLoS One. 2013. PMID: 23776472 Free PMC article.
Here we provide the first characterization of the orphan gene CLEC2L. In contrast to other CLEC2 family members, CLEC2L is conserved among mammals and located outside of the NKC. ...Thus CLEC2L-encoded CTLRs were designated BACL (brain-associated C-type lecti …
Here we provide the first characterization of the orphan gene CLEC2L. In contrast to other CLEC2 family members, CLEC2L is con …
Transcriptional profiling of innate immune responses in sheep PBMCs induced by Haemonchus contortus soluble extracts.
Wang S, Hu D, Wang C, Tang X, Du M, Gu X, Suo J, Hu M, Fang R, Zhu X, Zhang X, Du A, Suo X, Liu X. Wang S, et al. Parasit Vectors. 2019 Apr 25;12(1):182. doi: 10.1186/s13071-019-3441-8. Parasit Vectors. 2019. PMID: 31023355 Free PMC article.
Therefore, we stimulated sheep peripheral blood mononuclear cells (PBMCs) with H. contortus soluble extract (HcAg) and performed transcriptional profiling. RESULTS: HcAg upregulated two genetically linked CLRs (CLEC2L and KLRG2), two NLRs attenuating inflammation (NLRP12 a …
Therefore, we stimulated sheep peripheral blood mononuclear cells (PBMCs) with H. contortus soluble extract (HcAg) and performed transcripti …