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Impact of Nutritional Deficiencies on Children and Young Adults with Crohn's Disease Undergoing Intraabdominal Surgery.

McLoughlin RJ, McKie K, Hirsh MP, Cleary MA, Aidlen JT.

J Pediatr Surg. 2019 Oct 31. pii: S0022-3468(19)30747-X. doi: 10.1016/j.jpedsurg.2019.10.012. [Epub ahead of print]


Toy Guns, Real Danger: An Update on Pediatric Injury Patterns Related to Nonpowder Weapons.

McLoughlin RJ, Stetson A, Green J, Hirsh MP, Cleary MA, Aidlen JT.

J Pediatr Surg. 2019 Oct 25. pii: S0022-3468(19)30721-3. doi: 10.1016/j.jpedsurg.2019.09.068. [Epub ahead of print]


Ten years of enzyme replacement therapy in paediatric onset mucopolysaccharidosis II in England.

Broomfield A, Davison J, Roberts J, Stewart C, Hensman P, Beesley C, Tylee K, Rust S, Schwahn B, Jameson E, Vijay S, Santra S, Sreekantam S, Ramaswami U, Chakrapani A, Raiman J, Cleary MA, Jones SA.

Mol Genet Metab. 2019 Jul 30. pii: S1096-7192(19)30459-7. doi: 10.1016/j.ymgme.2019.07.016. [Epub ahead of print]


Variable management strategies for NEC totalis: a national survey.

Pyle AK, Shabanova V, Cleary MA, Ozgediz D, Cummings CL, Kamin DS, Mercurio MR.

J Perinatol. 2019 Nov;39(11):1521-1527. doi: 10.1038/s41372-019-0448-0. Epub 2019 Aug 1.


Hospitalizations for pediatric dog bite injuries in the United States.

McLoughlin RJ, Cournoyer L, Hirsh MP, Cleary MA, Aidlen JT.

J Pediatr Surg. 2019 Jul 9. pii: S0022-3468(19)30453-1. doi: 10.1016/j.jpedsurg.2019.06.025. [Epub ahead of print]


Risk Factors for Venous Thromboembolism in Children and Young Adults With Inflammatory Bowel Disease.

McKie K, McLoughlin RJ, Hirsh MP, Cleary MA, Aidlen JT.

J Surg Res. 2019 Nov;243:173-179. doi: 10.1016/j.jss.2019.04.087. Epub 2019 Jun 7.


Young lives cut short: The relationship between firearms and pediatric suicide.

McLoughlin RJ, Hazeltine M, Dacier BM, Hirsh MP, Cleary MA, Aidlen JT.

J Trauma Acute Care Surg. 2019 Jul;87(1):161-167. doi: 10.1097/TA.0000000000002257.


Routine postnatal chest x-ray and intensive care admission are unnecessary for a majority of infants with congenital lung malformations.

Greig CJ, Keiser AM, Cleary MA, Stitelman DH, Christison-Lagay ER, Ozgediz DE, Solomon DG, Caty MG, Cowles RA.

J Pediatr Surg. 2019 Apr;54(4):670-674. doi: 10.1016/j.jpedsurg.2018.10.063. Epub 2018 Nov 6.


International working group identifies need for newborn screening for mucopolysaccharidosis type I but states that existing hurdles must be overcome.

Parini R, Broomfield A, Cleary MA, De Meirleir L, Di Rocco M, Fathalla WM, Guffon N, Lampe C, Lund AM, Scarpa M, Tylki-Szymańska A, Zeman J.

Acta Paediatr. 2018 Dec;107(12):2059-2065. doi: 10.1111/apa.14587. Epub 2018 Oct 23. Review.


Fifteen-minute consultation: Red flags for metabolic disease in routine bloods.

Hart C, Davison JE, Cleary MA.

Arch Dis Child Educ Pract Ed. 2019 Feb;104(1):16-19. doi: 10.1136/archdischild-2017-313886. Epub 2018 May 19. No abstract available.


Repair of a mycotic abdominal aortic aneurysm in a neonate using an everted jugular vein patch.

Ahle SL, Cardella JA, Cleary MA, Stitelman DH, Sarac TP, Caty MG.

J Vasc Surg Cases Innov Tech. 2017 Nov 2;3(4):218-220. doi: 10.1016/j.jvscit.2017.08.003. eCollection 2017 Dec.


Novel application and serial evaluation of tissue-engineered portal vein grafts in a murine model.

Maxfield MW, Stacy MR, Kurobe H, Tara S, Yi T, Cleary MA, Zhuang ZW, Rodriguez-Davalos MI, Emre SH, Iwakiri Y, Shinoka T, Breuer CK.

Regen Med. 2017 Dec;12(8):929-938. doi: 10.2217/rme-2017-0021. Epub 2017 Dec 7.


Dynamic Regulation of TWIST1 Expression During Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.

Cleary MA, Narcisi R, Albiero A, Jenner F, de Kroon LMG, Koevoet WJLM, Brama PAJ, van Osch GJVM.

Stem Cells Dev. 2017 May 15;26(10):751-761. doi: 10.1089/scd.2016.0308. Epub 2017 Mar 16.


Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context.

Severyn B, Nguyen T, Altman MD, Li L, Nagashima K, Naumov GN, Sathyanarayanan S, Cook E, Morris E, Ferrer M, Arthur B, Benita Y, Watters J, Loboda A, Hermes J, Gilliland DG, Cleary MA, Carroll PM, Strack P, Tudor M, Andersen JN.

J Biomol Screen. 2016 Oct;21(9):989-97. doi: 10.1177/1087057116658646. Epub 2016 Jul 26.


Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.

de Kroon LM, Narcisi R, Blaney Davidson EN, Cleary MA, van Beuningen HM, Koevoet WJ, van Osch GJ, van der Kraan PM.

PLoS One. 2015 Dec 31;10(12):e0146124. doi: 10.1371/journal.pone.0146124. eCollection 2015.


Expression of CD105 on expanded mesenchymal stem cells does not predict their chondrogenic potential.

Cleary MA, Narcisi R, Focke K, van der Linden R, Brama PA, van Osch GJ.

Osteoarthritis Cartilage. 2016 May;24(5):868-72. doi: 10.1016/j.joca.2015.11.018. Epub 2015 Dec 12.


Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux.

McLaren DG, Previs SF, Phair RD, Stout SJ, Xie D, Chen Y, Salituro GM, Xu SS, Castro-Perez JM, Opiteck GJ, Akinsanya KO, Cleary MA, Dansky HM, Johns DG, Roddy TP.

J Lipid Res. 2016 Mar;57(3):398-409. doi: 10.1194/jlr.M063842. Epub 2015 Dec 9.


Response of 33 UK patients with infantile-onset Pompe disease to enzyme replacement therapy.

Broomfield A, Fletcher J, Davison J, Finnegan N, Fenton M, Chikermane A, Beesley C, Harvey K, Cullen E, Stewart C, Santra S, Vijay S, Champion M, Abulhoul L, Grunewald S, Chakrapani A, Cleary MA, Jones SA, Vellodi A.

J Inherit Metab Dis. 2016 Mar;39(2):261-71. doi: 10.1007/s10545-015-9898-5. Epub 2015 Oct 26.


Seizures Due to a KCNQ2 Mutation: Treatment with Vitamin B6.

Reid ES, Williams H, Stabej Ple Q, James C, Ocaka L, Bacchelli C, Footitt EJ, Boyd S, Cleary MA, Mills PB, Clayton PT.

JIMD Rep. 2016;27:79-84. doi: 10.1007/8904_2015_460. Epub 2015 Oct 8.


Effect of Error Propagation in Stable Isotope Tracer Studies: An Approach for Estimating Impact on Apparent Biochemical Flux.

Previs SF, Herath K, Castro-Perez J, Mahsut A, Zhou H, McLaren DG, Shah V, Rohm RJ, Stout SJ, Zhong W, Wang SP, Johns DG, Hubbard BK, Cleary MA, Roddy TP.

Methods Enzymol. 2015;561:331-58. doi: 10.1016/bs.mie.2015.06.021. Epub 2015 Aug 19. Review.


Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation.

Narcisi R, Cleary MA, Brama PA, Hoogduijn MJ, Tüysüz N, ten Berge D, van Osch GJ.

Stem Cell Reports. 2015 Mar 10;4(3):459-72. doi: 10.1016/j.stemcr.2015.01.017. Epub 2015 Feb 26.


Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma.

Paulson KG, Tegeder A, Willmes C, Iyer JG, Afanasiev OK, Schrama D, Koba S, Thibodeau R, Nagase K, Simonson WT, Seo A, Koelle DM, Madeleine M, Bhatia S, Nakajima H, Sano S, Hardwick JS, Disis ML, Cleary MA, Becker JC, Nghiem P.

Cancer Immunol Res. 2014 Nov;2(11):1071-9. doi: 10.1158/2326-6066.CIR-14-0005. Epub 2014 Aug 12.


Inborn Error of Metabolism (IEM) screening in Singapore by electrospray ionization-tandem mass spectrometry (ESI/MS/MS): An 8 year journey from pilot to current program.

Lim JS, Tan ES, John CM, Poh S, Yeo SJ, Ang JS, Adakalaisamy P, Rozalli RA, Hart C, Tan ET, Ranieri E, Rajadurai VS, Cleary MA, Goh DL.

Mol Genet Metab. 2014 Sep-Oct;113(1-2):53-61. doi: 10.1016/j.ymgme.2014.07.018. Epub 2014 Jul 23.


Effects of anacetrapib on plasma lipids, apolipoproteins and PCSK9 in healthy, lean rhesus macaques.

Roddy TP, McLaren DG, Chen Y, Xie D, Dunn K, Kulick A, Szeto D, Forrest G, Albanese K, Donnelly M, Gai C, Gewain A, Lederman H, Jensen KK, Ai X, Vachal P, Akinsanya KO, Cleary MA, Previs SF, Dansky HM, Johns DG.

Eur J Pharmacol. 2014 Oct 5;740:410-6. doi: 10.1016/j.ejphar.2014.04.015. Epub 2014 Apr 21.


Determination of low levels of 2H-labeling using high-resolution mass spectrometry: application in studies of lipid flux and beyond.

Herath KB, Zhong W, Yang J, Mahsut A, Rohm RJ, Shah V, Castro-Perez J, Zhou H, Attygalle AB, Kang L, Singh S, Johns DG, Cleary MA, Hubbard BK, Previs SF, Roddy TP.

Rapid Commun Mass Spectrom. 2014 Feb 15;28(3):239-44. doi: 10.1002/rcm.6776.


FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells.

Conrad W, Major MB, Cleary MA, Ferrer M, Roberts B, Marine S, Chung N, Arthur WT, Moon RT, Berndt JD, Chien AJ.

Version 2. F1000Res. 2013 May 31 [revised 2013 Jan 1];2:134. doi: 10.12688/f1000research.2-134.v2. eCollection 2013.


A distinct mitochondrial myopathy, lactic acidosis and sideroblastic anemia (MLASA) phenotype associates with YARS2 mutations.

Shahni R, Wedatilake Y, Cleary MA, Lindley KJ, Sibson KR, Rahman S.

Am J Med Genet A. 2013 Sep;161A(9):2334-8. doi: 10.1002/ajmg.a.36065. Epub 2013 Aug 5.


Thermoregulatory, cardiovascular, and perceptual responses to intermittent cooling during exercise in a hot, humid outdoor environment.

Cleary MA, Toy MG, Lopez RM.

J Strength Cond Res. 2014 Mar;28(3):792-806. doi: 10.1519/JSC.0b013e3182a20f57.


New methodologies for studying lipid synthesis and turnover: looking backwards to enable moving forwards.

Previs SF, McLaren DG, Wang SP, Stout SJ, Zhou H, Herath K, Shah V, Miller PL, Wilsie L, Castro-Perez J, Johns DG, Cleary MA, Roddy TP.

Biochim Biophys Acta. 2014 Mar;1842(3):402-13. doi: 10.1016/j.bbadis.2013.05.019. Epub 2013 May 22. Review.


Use of [13C18] oleic acid and mass isotopomer distribution analysis to study synthesis of plasma triglycerides in vivo: analytical and experimental considerations.

McLaren DG, Cardasis HL, Stout SJ, Wang SP, Mendoza V, Castro-Perez JM, Miller PL, Murphy BA, Cumiskey AM, Cleary MA, Johns DG, Previs SF, Roddy TP.

Anal Chem. 2013 Jul 2;85(13):6287-94. doi: 10.1021/ac400363k. Epub 2013 Jun 10.


FGF, TGFβ and Wnt crosstalk: embryonic to in vitro cartilage development from mesenchymal stem cells.

Cleary MA, van Osch GJ, Brama PA, Hellingman CA, Narcisi R.

J Tissue Eng Regen Med. 2015 Apr;9(4):332-42. doi: 10.1002/term.1744. Epub 2013 Apr 11. Review.


Omental vein catheter thrombolysis for acute porto-mesenteric vein thrombosis.

Fonseca AL, Cleary MA, Cholewczynski W, Sumpio BE, Atweh NA.

Ann Vasc Surg. 2013 May;27(4):497.e1-4. doi: 10.1016/j.avsg.2012.09.009. Epub 2013 Apr 5.


Superficial cooling does not decrease core body temperature before, during, or after exercise in an American football uniform.

Lopez RM, Eberman LE, Cleary MA.

J Strength Cond Res. 2012 Dec;26(12):3432-40. doi: 10.1519/JSC.0b013e3182736e5b.


Hydration behaviors before and after an educational and prescribed hydration intervention in adolescent athletes.

Cleary MA, Hetzler RK, Wasson D, Wages JJ, Stickley C, Kimura IF.

J Athl Train. 2012 May-Jun;47(3):273-81. doi: 10.4085/1062-6050-47.3.05.


A distinct Smoothened mutation causes severe cerebellar developmental defects and medulloblastoma in a novel transgenic mouse model.

Dey J, Ditzler S, Knoblaugh SE, Hatton BA, Schelter JM, Cleary MA, Mecham B, Rorke-Adams LB, Olson JM.

Mol Cell Biol. 2012 Oct;32(20):4104-15. Epub 2012 Aug 6.


A multiplexed siRNA screening strategy to identify genes in the PARP pathway.

Stec E, Locco L, Szymanski S, Bartz SR, Toniatti C, Needham RH, Palmieri A, Carleton M, Cleary MA, Jackson AL, Linsley PS, Strulovici B, Ferrer M, Santini F.

J Biomol Screen. 2012 Dec;17(10):1316-28. doi: 10.1177/1087057112453071. Epub 2012 Jul 10.


Vascular tissue engineering: the next generation.

Cleary MA, Geiger E, Grady C, Best C, Naito Y, Breuer C.

Trends Mol Med. 2012 Jul;18(7):394-404. doi: 10.1016/j.molmed.2012.04.013. Epub 2012 Jun 12. Review.


Functional genomics identifies therapeutic targets for MYC-driven cancer.

Toyoshima M, Howie HL, Imakura M, Walsh RM, Annis JE, Chang AN, Frazier J, Chau BN, Loboda A, Linsley PS, Cleary MA, Park JR, Grandori C.

Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9545-50. doi: 10.1073/pnas.1121119109. Epub 2012 May 23.


Synthetic lethality of PARP inhibition in BRCA-network disrupted tumor cells is associated with interferon pathway activation and enhanced by interferon-γ.

Warrener P, Kim S, Williams SM, Biery M, Gordon M, Toniatti C, Cleary MA, Linsley PS, Carleton M.

Apoptosis. 2012 Jul;17(7):691-701. doi: 10.1007/s10495-012-0707-4.


Exertional rhabdomyolysis in an adolescent athlete during preseason conditioning: a perfect storm.

Cleary MA, Sadowski KA, Lee SY, Miller GL, Nichols AW.

J Strength Cond Res. 2011 Dec;25(12):3506-13. doi: 10.1519/JSC.0b013e318216302f.


p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers.

Sundaram P, Hultine S, Smith LM, Dews M, Fox JL, Biyashev D, Schelter JM, Huang Q, Cleary MA, Volpert OV, Thomas-Tikhonenko A.

Cancer Res. 2011 Dec 15;71(24):7490-501. doi: 10.1158/0008-5472.CAN-11-1124. Epub 2011 Oct 25.


Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma.

Ivanovska I, Zhang C, Liu AM, Wong KF, Lee NP, Lewis P, Philippar U, Bansal D, Buser C, Scott M, Mao M, Poon RT, Fan ST, Cleary MA, Luk JM, Dai H.

PLoS One. 2011;6(9):e24582. doi: 10.1371/journal.pone.0024582. Epub 2011 Sep 16.


Mutations in the mitochondrial complex I assembly factor NDUFAF1 cause fatal infantile hypertrophic cardiomyopathy.

Fassone E, Taanman JW, Hargreaves IP, Sebire NJ, Cleary MA, Burch M, Rahman S.

J Med Genet. 2011 Oct;48(10):691-7. doi: 10.1136/jmedgenet-2011-100340.


DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival.

Luk JM, Burchard J, Zhang C, Liu AM, Wong KF, Shek FH, Lee NP, Fan ST, Poon RT, Ivanovska I, Philippar U, Cleary MA, Buser CA, Shaw PM, Lee CN, Tenen DG, Dai H, Mao M.

J Biol Chem. 2011 Sep 2;286(35):30706-13. doi: 10.1074/jbc.M111.229831. Epub 2011 Jul 7.


HIF induces human embryonic stem cell markers in cancer cells.

Mathieu J, Zhang Z, Zhou W, Wang AJ, Heddleston JM, Pinna CM, Hubaud A, Stadler B, Choi M, Bar M, Tewari M, Liu A, Vessella R, Rostomily R, Born D, Horwitz M, Ware C, Blau CA, Cleary MA, Rich JN, Ruohola-Baker H.

Cancer Res. 2011 Jul 1;71(13):4640-52. doi: 10.1158/0008-5472.CAN-10-3320. Epub 2011 Jun 28.


Comparisons of age-predicted maximum heart rate equations in college-aged subjects.

Cleary MA, Hetzler RK, Wages JJ, Lentz MA, Stickley CD, Kimura IF.

J Strength Cond Res. 2011 Sep;25(9):2591-7. doi: 10.1519/JSC.0b013e3182001832.


Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.

Paulson KG, Iyer JG, Tegeder AR, Thibodeau R, Schelter J, Koba S, Schrama D, Simonson WT, Lemos BD, Byrd DR, Koelle DM, Galloway DA, Leonard JH, Madeleine MM, Argenyi ZB, Disis ML, Becker JC, Cleary MA, Nghiem P.

J Clin Oncol. 2011 Apr 20;29(12):1539-46. doi: 10.1200/JCO.2010.30.6308. Epub 2011 Mar 21.


Development of a heat-illness screening instrument using the Delphi panel technique.

Eberman LE, Cleary MA.

J Athl Train. 2011 Mar-Apr;46(2):176-84. doi: 10.4085/1062-6050-46.2.176.


Myc overexpression brings out unexpected antiapoptotic effects of miR-34a.

Sotillo E, Laver T, Mellert H, Schelter JM, Cleary MA, McMahon S, Thomas-Tikhonenko A.

Oncogene. 2011 Jun 2;30(22):2587-94. doi: 10.1038/onc.2010.634. Epub 2011 Feb 7.


The myc-miR-17~92 axis blunts TGF{beta} signaling and production of multiple TGF{beta}-dependent antiangiogenic factors.

Dews M, Fox JL, Hultine S, Sundaram P, Wang W, Liu YY, Furth E, Enders GH, El-Deiry W, Schelter JM, Cleary MA, Thomas-Tikhonenko A.

Cancer Res. 2010 Oct 15;70(20):8233-46. doi: 10.1158/0008-5472.CAN-10-2412. Epub 2010 Oct 12.

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