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Items: 1 to 50 of 153

1.

KLF13 regulates the differentiation-dependent human papillomavirus life cycle in keratinocytes through STAT5 and IL-8.

Zhang W, Hong S, Maniar KP, Cheng S, Jie C, Rademaker AW, Krensky AM, Clayberger C.

Oncogene. 2016 Oct 20;35(42):5565-5575. doi: 10.1038/onc.2016.97. Epub 2016 Apr 4.

PMID:
27041562
2.

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes.

Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, Krensky AM, Martinvalet D, Lieberman J.

Cell. 2015 May 21;161(5):1229. doi: 10.1016/j.cell.2015.05.021. Epub 2015 May 21. No abstract available.

3.

Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes.

Walch M, Dotiwala F, Mulik S, Thiery J, Kirchhausen T, Clayberger C, Krensky AM, Martinvalet D, Lieberman J.

Cell. 2014 Jun 5;157(6):1309-23. doi: 10.1016/j.cell.2014.03.062. Erratum in: Cell. 2015 May 21;161(5):1229.

4.

KLF13 cooperates with c-Maf to regulate IL-4 expression in CD4+ T cells.

Kwon SJ, Crespo-Barreto J, Zhang W, Wang T, Kim DS, Krensky A, Clayberger C.

J Immunol. 2014 Jun 15;192(12):5703-9. doi: 10.4049/jimmunol.1302830. Epub 2014 May 12.

5.

The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterus.

Heard ME, Pabona JM, Clayberger C, Krensky AM, Simmen FA, Simmen RC.

Biol Reprod. 2012 Nov 16;87(5):115. doi: 10.1095/biolreprod.112.102251. Print 2012 Nov.

6.

Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes.

Kim DS, Zhang W, Millman SE, Hwang BJ, Kwon SJ, Clayberger C, Pagano M, Krensky AM.

Blood. 2012 Aug 23;120(8):1658-67. doi: 10.1182/blood-2012-03-415968. Epub 2012 Jul 13.

7.

15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity.

Clayberger C, Finn MW, Wang T, Saini R, Wilson C, Barr VA, Sabatino M, Castiello L, Stroncek D, Krensky AM.

J Immunol. 2012 Jun 15;188(12):6119-26. doi: 10.4049/jimmunol.1200570. Epub 2012 May 14.

8.

15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level.

Castiello L, Stroncek DF, Finn MW, Wang E, Marincola FM, Clayberger C, Krensky AM, Sabatino M.

J Transl Med. 2011 Apr 18;9:41. doi: 10.1186/1479-5876-9-41.

9.

KLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells.

Lai D, Zhu J, Wang T, Hu-Li J, Terabe M, Berzofsky JA, Clayberger C, Krensky AM.

J Exp Med. 2011 May 9;208(5):1093-103. doi: 10.1084/jem.20101527. Epub 2011 Apr 11.

10.

Granulysin delivered by cytotoxic cells damages endoplasmic reticulum and activates caspase-7 in target cells.

Saini RV, Wilson C, Finn MW, Wang T, Krensky AM, Clayberger C.

J Immunol. 2011 Mar 15;186(6):3497-504. doi: 10.4049/jimmunol.1003409. Epub 2011 Feb 4.

11.

Monocyte-derived DC maturation strategies and related pathways: a transcriptional view.

Castiello L, Sabatino M, Jin P, Clayberger C, Marincola FM, Krensky AM, Stroncek DF.

Cancer Immunol Immunother. 2011 Apr;60(4):457-66. doi: 10.1007/s00262-010-0954-6. Epub 2011 Jan 22. Review.

12.

Expression and purification of 15 kDa granulysin utilizing an insect cell secretion system.

Finn MW, Clayberger C, Krensky AM.

Protein Expr Purif. 2011 Jan;75(1):70-4. doi: 10.1016/j.pep.2010.07.009. Epub 2010 Jul 30.

13.

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.

Tewary P, Yang D, de la Rosa G, Li Y, Finn MW, Krensky AM, Clayberger C, Oppenheim JJ.

Blood. 2010 Nov 4;116(18):3465-74. doi: 10.1182/blood-2010-03-273953. Epub 2010 Jul 21.

14.

Cytolytic molecules in rejection.

Clayberger C.

Curr Opin Organ Transplant. 2009 Feb;14(1):30-3. doi: 10.1097/MOT.0b013e32831c8462. Review.

PMID:
19337143
15.

A human T cell-specific molecule is a member of a new gene family. 1988.

Schall TJ, Jongstra J, Dyer BJ, Jorgensen J, Clayberger C, Davis MM, Krensky AM.

J Immunol. 2009 Apr 1;182(7):3947-54. No abstract available.

16.

Biology and clinical relevance of granulysin.

Krensky AM, Clayberger C.

Tissue Antigens. 2009 Mar;73(3):193-8. doi: 10.1111/j.1399-0039.2008.01218.x. Review.

17.

In vitro and in vivo antimicrobial activity of granulysin-derived peptides against Vibrio cholerae.

da Silva AP, Unks D, Lyu SC, Ma J, Zbozien-Pacamaj R, Chen X, Krensky AM, Clayberger C.

J Antimicrob Chemother. 2008 May;61(5):1103-9. doi: 10.1093/jac/dkn058. Epub 2008 Feb 29.

18.

IL-24 modulates IFN-gamma expression in patients with tuberculosis.

Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C.

Immunol Lett. 2008 Apr 15;117(1):57-62. doi: 10.1016/j.imlet.2007.11.018. Epub 2007 Dec 26.

19.

IL-9 is associated with an impaired Th1 immune response in patients with tuberculosis.

Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C.

Clin Immunol. 2008 Feb;126(2):202-10. Epub 2007 Nov 26.

PMID:
18032114
20.

Increased host neuronal survival and motor function in BMT Parkinsonian mice: involvement of immunosuppression.

Keshet GI, Tolwani RJ, Trejo A, Kraft P, Doyonnas R, Clayberger C, Weimann JM, Blau HM.

J Comp Neurol. 2007 Oct 20;504(6):690-701.

PMID:
17722033
21.

Biophysical analysis of the interaction of granulysin-derived peptides with enterobacterial endotoxins.

Chen X, Howe J, Andrä J, Rössle M, Richter W, da Silva AP, Krensky AM, Clayberger C, Brandenburg K.

Biochim Biophys Acta. 2007 Oct;1768(10):2421-31. Epub 2007 May 22.

22.

Interaction of PRP4 with Kruppel-like factor 13 regulates CCL5 transcription.

Huang B, Ahn YT, McPherson L, Clayberger C, Krensky AM.

J Immunol. 2007 Jun 1;178(11):7081-7.

23.

Unique gene expression profiles in infants vaccinated with different strains of Mycobacterium bovis bacille Calmette-Guerin.

Wu B, Huang C, Garcia L, Ponce de Leon A, Osornio JS, Bobadilla-del-Valle M, Ferreira L, Canizales S, Small P, Kato-Maeda M, Krensky AM, Clayberger C.

Infect Immun. 2007 Jul;75(7):3658-64. Epub 2007 May 14.

24.

Kruppel-like transcription factor 13 regulates T lymphocyte survival in vivo.

Zhou M, McPherson L, Feng D, Song A, Dong C, Lyu SC, Zhou L, Shi X, Ahn YT, Wang D, Clayberger C, Krensky AM.

J Immunol. 2007 May 1;178(9):5496-504.

25.

Messenger RNA expression of IL-8, FOXP3, and IL-12beta differentiates latent tuberculosis infection from disease.

Wu B, Huang C, Kato-Maeda M, Hopewell PC, Daley CL, Krensky AM, Clayberger C.

J Immunol. 2007 Mar 15;178(6):3688-94.

26.

Granulysin-mediated tumor rejection in transgenic mice.

Huang LP, Lyu SC, Clayberger C, Krensky AM.

J Immunol. 2007 Jan 1;178(1):77-84.

27.

Dynamic interplay of transcriptional machinery and chromatin regulates "late" expression of the chemokine RANTES in T lymphocytes.

Ahn YT, Huang B, McPherson L, Clayberger C, Krensky AM.

Mol Cell Biol. 2007 Jan;27(1):253-66. Epub 2006 Oct 30.

28.

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells.

Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA.

J Exp Med. 2006 Jul 10;203(7):1701-11. Epub 2006 Jul 3.

29.

Cell selectivity correlates with membrane-specific interactions: a case study on the antimicrobial peptide G15 derived from granulysin.

Ramamoorthy A, Thennarasu S, Tan A, Lee DK, Clayberger C, Krensky AM.

Biochim Biophys Acta. 2006 Feb;1758(2):154-63. Epub 2006 Mar 10.

30.

Granulysin: a novel host defense molecule.

Krensky AM, Clayberger C.

Am J Transplant. 2005 Aug;5(8):1789-92. Review.

31.

Glycosylated recombinant human XCL1/lymphotactin exhibits enhanced biologic activity.

Dong C, Chua A, Ganguly B, Krensky AM, Clayberger C.

J Immunol Methods. 2005 Jul;302(1-2):136-44.

PMID:
15992811
32.

Granulysin, a cytolytic molecule, is also a chemoattractant and proinflammatory activator.

Deng A, Chen S, Li Q, Lyu SC, Clayberger C, Krensky AM.

J Immunol. 2005 May 1;174(9):5243-8.

33.

Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin.

Li Q, Dong C, Deng A, Katsumata M, Nakadai A, Kawada T, Okada S, Clayberger C, Krensky AM.

Antimicrob Agents Chemother. 2005 Jan;49(1):388-97.

34.

A novel apoptosis pathway activated by the carboxyl terminus of p21.

Dong C, Li Q, Lyu SC, Krensky AM, Clayberger C.

Blood. 2005 Feb 1;105(3):1187-94. Epub 2004 Oct 5.

PMID:
15466931
35.

DQ 65-79, a peptide derived from HLA class II, mimics p21 to block T cell proliferation.

Dong C, Lyu SC, Krensky AM, Clayberger C.

J Immunol. 2003 Nov 15;171(10):5064-70.

36.

Granulysin.

Clayberger C, Krensky AM.

Curr Opin Immunol. 2003 Oct;15(5):560-5. Review.

PMID:
14499265
37.

Intracellular mediators of granulysin-induced cell death.

Okada S, Li Q, Whitin JC, Clayberger C, Krensky AM.

J Immunol. 2003 Sep 1;171(5):2556-62.

38.

Protein kinase B/Akt is essential for the insulin- but not progesterone-stimulated resumption of meiosis in Xenopus oocytes.

Andersen CB, Sakaue H, Nedachi T, Kovacina KS, Clayberger C, Conti M, Roth RA.

Biochem J. 2003 Jan 15;369(Pt 2):227-38.

39.

A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes.

Nikolcheva T, Pyronnet S, Chou SY, Sonenberg N, Song A, Clayberger C, Krensky AM.

J Clin Invest. 2002 Jul;110(1):119-26.

40.

Functional domains and DNA-binding sequences of RFLAT-1/KLF13, a Krüppel-like transcription factor of activated T lymphocytes.

Song A, Patel A, Thamatrakoln K, Liu C, Feng D, Clayberger C, Krensky AM.

J Biol Chem. 2002 Aug 16;277(33):30055-65. Epub 2002 Jun 5.

41.

DQ 65-79, a peptide derived from HLA class II, induces I kappa B expression.

Jiang Y, Chen D, Lyu SC, Ling X, Krensky AM, Clayberger C.

J Immunol. 2002 Apr 1;168(7):3323-8.

42.

A distinct pathway of cell-mediated apoptosis initiated by granulysin.

Kaspar AA, Okada S, Kumar J, Poulain FR, Drouvalakis KA, Kelekar A, Hanson DA, Kluck RM, Hitoshi Y, Johnson DE, Froelich CJ, Thompson CB, Newmeyer DD, Anel A, Clayberger C, Krensky AM.

J Immunol. 2001 Jul 1;167(1):350-6.

43.

Granulysin blocks replication of varicella-zoster virus and triggers apoptosis of infected cells.

Hata A, Zerboni L, Sommer M, Kaspar AA, Clayberger C, Krensky AM, Arvin AM.

Viral Immunol. 2001;14(2):125-33.

PMID:
11398808
44.

Granulysin: a novel antimicrobial.

Kumar J, Okada S, Clayberger C, Krensky AM.

Expert Opin Investig Drugs. 2001 Feb;10(2):321-9. Review.

PMID:
11178344
45.

Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation.

Sarwal MM, Jani A, Chang S, Huie P, Wang Z, Salvatierra O Jr, Clayberger C, Sibley R, Krensky AM, Pavlakis M.

Hum Immunol. 2001 Jan;62(1):21-31.

PMID:
11165712
46.

Granulysin, a T cell product, kills bacteria by altering membrane permeability.

Ernst WA, Thoma-Uszynski S, Teitelbaum R, Ko C, Hanson DA, Clayberger C, Krensky AM, Leippe M, Bloom BR, Ganz T, Modlin RL.

J Immunol. 2000 Dec 15;165(12):7102-8.

47.

A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection.

Horuk R, Clayberger C, Krensky AM, Wang Z, Grone HJ, Weber C, Weber KS, Nelson PJ, May K, Rosser M, Dunning L, Liang M, Buckman B, Ghannam A, Ng HP, Islam I, Bauman JG, Wei GP, Monahan S, Xu W, Snider RM, Morrissey MM, Hesselgesser J, Perez HD.

J Biol Chem. 2001 Feb 9;276(6):4199-204. Epub 2000 Oct 27.

48.

An immunosuppressive and anti-inflammatory HLA class I-derived peptide binds vascular cell adhesion molecule-1.

Ling X, Tamaki T, Xiao Y, Kamangar S, Clayberger C, Lewis DB, Krensky AM.

Transplantation. 2000 Aug 27;70(4):662-7.

PMID:
10972226
49.

Bactericidal and tumoricidal activities of synthetic peptides derived from granulysin.

Wang Z, Choice E, Kaspar A, Hanson D, Okada S, Lyu SC, Krensky AM, Clayberger C.

J Immunol. 2000 Aug 1;165(3):1486-90.

50.

Proliferating cell nuclear antigen as the cell cycle sensor for an HLA-derived peptide blocking T cell proliferation.

Ling X, Kamangar S, Boytim ML, Kelman Z, Huie P, Lyu SC, Sibley RK, Hurwitz J, Clayberger C, Krensky AM.

J Immunol. 2000 Jun 15;164(12):6188-92.

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