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Items: 9


MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2.

Martínez de Paz A, Khajavi L, Martin H, Claveria-Gimeno R, Tom Dieck S, Cheema MS, Sanchez-Mut JV, Moksa MM, Carles A, Brodie NI, Sheikh TI, Freeman ME, Petrotchenko EV, Borchers CH, Schuman EM, Zytnicki M, Velazquez-Campoy A, Abian O, Hirst M, Esteller M, Vincent JB, Malnou CE, Ausió J.

Epigenetics Chromatin. 2019 Oct 10;12(1):63. doi: 10.1186/s13072-019-0298-1.


Tinkering with Binding Polynomials in Isothermal Titration Calorimetry.

Claveria-Gimeno R, Vega S, Abian O, Velazquez-Campoy A.

Methods Mol Biol. 2019;1964:185-213. doi: 10.1007/978-1-4939-9179-2_14.


Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position.

Gálvez JA, Clavería-Gimeno R, Galano-Frutos JJ, Sancho J, Velázquez-Campoy A, Abian O, Díaz-de-Villegas MD.

Eur J Med Chem. 2019 Jun 1;171:401-419. doi: 10.1016/j.ejmech.2019.03.019. Epub 2019 Mar 12.


Differential NtcA Responsiveness to 2-Oxoglutarate Underlies the Diversity of C/N Balance Regulation in Prochlorococcus.

Domínguez-Martín MA, López-Lozano A, Clavería-Gimeno R, Velázquez-Campoy A, Seidel G, Burkovski A, Díez J, García-Fernández JM.

Front Microbiol. 2018 Jan 9;8:2641. doi: 10.3389/fmicb.2017.02641. eCollection 2017.


Thermodynamics of cooperative binding of FAD to human NQO1: Implications to understanding cofactor-dependent function and stability of the flavoproteome.

Clavería-Gimeno R, Velazquez-Campoy A, Pey AL.

Arch Biochem Biophys. 2017 Dec 15;636:17-27. doi: 10.1016/ Epub 2017 Oct 31.


A look at ligand binding thermodynamics in drug discovery.

Claveria-Gimeno R, Vega S, Abian O, Velazquez-Campoy A.

Expert Opin Drug Discov. 2017 Apr;12(4):363-377. doi: 10.1080/17460441.2017.1297418. Epub 2017 Mar 1. Review.


The intervening domain from MeCP2 enhances the DNA affinity of the methyl binding domain and provides an independent DNA interaction site.

Claveria-Gimeno R, Lanuza PM, Morales-Chueca I, Jorge-Torres OC, Vega S, Abian O, Esteller M, Velazquez-Campoy A.

Sci Rep. 2017 Jan 31;7:41635. doi: 10.1038/srep41635.


Shell Cross-Linked Polymeric Micelles as Camptothecin Nanocarriers for Anti-HCV Therapy.

Jiménez-Pardo I, González-Pastor R, Lancelot A, Claveria-Gimeno R, Velázquez-Campoy A, Abian O, Ros MB, Sierra T.

Macromol Biosci. 2015 Oct;15(10):1381-91. doi: 10.1002/mabi.201500094. Epub 2015 Jun 5.


Rescuing compound bioactivity in a secondary cell-based screening by using γ-cyclodextrin as a molecular carrier.

Claveria-Gimeno R, Vega S, Grazu V, de la Fuente JM, Lanas A, Velazquez-Campoy A, Abian O.

Int J Nanomedicine. 2015 Mar 19;10:2249-59. doi: 10.2147/IJN.S79480. eCollection 2015.

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