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Mechano-biological adaptation of the pulmonary artery exposed to systemic conditions.

Vanderveken E, Vastmans J, Claus P, Verbeken E, Fehervary H, Van Hoof L, Vandendriessche K, Verbrugghe P, Famaey N, Rega F.

Sci Rep. 2020 Feb 17;10(1):2724. doi: 10.1038/s41598-020-59554-7.


Profilin2a-phosphorylation as a regulatory mechanism for actin dynamics.

Walter LM, Franz P, Lindner R, Tsiavaliaris G, Hensel N, Claus P.

FASEB J. 2020 Feb;34(2):2147-2160. doi: 10.1096/fj.201901883R. Epub 2019 Dec 12.


Altered adrenergic response in myocytes bordering a chronic myocardial infarction underlies in vivo triggered activity and repolarization instability.

Dries E, Amoni M, Vandenberk B, Johnson DM, Gilbert G, Nagaraju CK, Puertas RD, Abdesselem M, Santiago DJ, Roderick HL, Claus P, Willems R, Sipido KR.

J Physiol. 2020 Jan 3. doi: 10.1113/JP278839. [Epub ahead of print]


Resolution of pathogenic R-loops rescues motor neuron degeneration in spinal muscular atrophy.

Hensel N, Detering NT, Walter LM, Claus P.

Brain. 2020 Jan 1;143(1):2-5. doi: 10.1093/brain/awz394. No abstract available.


Low septal to lateral wall 18F-FDG ratio is highly associated with mechanical dyssynchrony in non-ischemic CRT candidates.

Degtiarova G, Claus P, Duchenne J, Cvijic M, Schramm G, Nuyts J, Voigt JU, Gheysens O.

EJNMMI Res. 2019 Dec 9;9(1):105. doi: 10.1186/s13550-019-0575-9.


HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0.

Hensel N, Raker V, Förthmann B, Detering NT, Kubinski S, Buch A, Katzilieris-Petras G, Spanier J, Gudi V, Wagenknecht S, Kopfnagel V, Werfel TA, Stangel M, Beineke A, Kalinke U, Paludan SR, Sodeik B, Claus P.

J Neuroinflammation. 2019 Dec 2;16(1):248. doi: 10.1186/s12974-019-1647-5.


Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle.

Schada von Borzyskowski L, Severi F, Krüger K, Hermann L, Gilardet A, Sippel F, Pommerenke B, Claus P, Cortina NS, Glatter T, Zauner S, Zarzycki J, Fuchs BM, Bremer E, Maier UG, Amann RI, Erb TJ.

Nature. 2019 Nov;575(7783):500-504. doi: 10.1038/s41586-019-1748-4. Epub 2019 Nov 13.


Impact of left bundle branch block on myocardial perfusion and metabolism: A positron emission tomography study.

Degtiarova G, Claus P, Duchenne J, Schramm G, Nuyts J, Verberne HJ, Voigt JU, Gheysens O.

J Nucl Cardiol. 2019 Oct 2. doi: 10.1007/s12350-019-01900-y. [Epub ahead of print]


Right ventricular strain rate during exercise accurately identifies male athletes with right ventricular arrhythmias.

Claeys M, Claessen G, Claus P, De Bosscher R, Dausin C, Voigt JU, Willems R, Heidbuchel H, La Gerche A.

Eur Heart J Cardiovasc Imaging. 2020 Mar 1;21(3):282-290. doi: 10.1093/ehjci/jez228.


FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.

Brand F, Förster A, Christians A, Bucher M, Thomé CM, Raab MS, Westphal M, Pietsch T, von Deimling A, Reifenberger G, Claus P, Hentschel B, Weller M, Weber RG.

Acta Neuropathol. 2020 Jan;139(1):175-192. doi: 10.1007/s00401-019-02067-z. Epub 2019 Aug 31.


Abnormal fatty acid metabolism is a core component of spinal muscular atrophy.

Deguise MO, Baranello G, Mastella C, Beauvais A, Michaud J, Leone A, De Amicis R, Battezzati A, Dunham C, Selby K, Warman Chardon J, McMillan HJ, Huang YT, Courtney NL, Mole AJ, Kubinski S, Claus P, Murray LM, Bowerman M, Gillingwater TH, Bertoli S, Parson SH, Kothary R.

Ann Clin Transl Neurol. 2019 Aug;6(8):1519-1532. doi: 10.1002/acn3.50855. Epub 2019 Jul 26.


Area of the pressure-strain loop during ejection as non-invasive index of left ventricular performance: a population study.

Cauwenberghs N, Tabassian M, Thijs L, Yang WY, Wei FF, Claus P, D'hooge J, Staessen JA, Kuznetsova T.

Cardiovasc Ultrasound. 2019 Aug 5;17(1):15. doi: 10.1186/s12947-019-0166-y.


Early or deferred cardiovascular magnetic resonance after ST-segment-elevation myocardial infarction for effective risk stratification.

Masci PG, Pavon AG, Pontone G, Symons R, Lorenzoni V, Francone M, Zalewski J, Barison A, Guglielmo M, Aquaro GD, Galea N, Muscogiuri G, Muller O, Carbone I, Baggiano A, Iglesias JF, Nessler J, Andreini D, Camici PG, Claus P, Luca L, Agati L, Janssens S, Schwitter J, Bogaert J.

Eur Heart J Cardiovasc Imaging. 2019 Jul 20. pii: jez179. doi: 10.1093/ehjci/jez179. [Epub ahead of print]


Inter-vendor reproducibility and accuracy of segmental left ventricular strain measurements using CMR feature tracking.

Dobrovie M, Barreiro-Pérez M, Curione D, Symons R, Claus P, Voigt JU, Bogaert J.

Eur Radiol. 2019 Dec;29(12):6846-6857. doi: 10.1007/s00330-019-06315-4. Epub 2019 Jul 11.


Non-invasive myocardial performance mapping using 3D echocardiographic stress-strain loops.

Pedrosa J, Duchenne J, Queirós S, Degtiarova G, Gheysens O, Claus P, Voigt JU, D'hooge J.

Phys Med Biol. 2019 Jun 5;64(11):115026. doi: 10.1088/1361-6560/ab21f8.


Vitamin D improves endothelial barrier integrity and counteracts inflammatory effects on endothelial progenitor cells.

Schröder-Heurich B, von Hardenberg S, Brodowski L, Kipke B, Meyer N, Borns K, von Kaisenberg CS, Brinkmann H, Claus P, von Versen-Höynck F.

FASEB J. 2019 Aug;33(8):9142-9153. doi: 10.1096/fj.201802750RR. Epub 2019 May 14.


Heart Rate Reserve in Fontan Patients: Chronotropic Incompetence or Hemodynamic Limitation?

Claessen G, La Gerche A, Van De Bruaene A, Claeys M, Willems R, Dymarkowski S, Bogaert J, Claus P, Budts W, Heidbuchel H, Gewillig M.

J Am Heart Assoc. 2019 May 7;8(9):e012008. doi: 10.1161/JAHA.119.012008.


Left Ventricular Remodeling Results in Homogenization of Myocardial Work Distribution.

Duchenne J, Turco A, Ünlü S, Pagourelias ED, Vunckx K, Degtiarova G, Bézy S, Cvijic M, Nuyts J, Claus P, Rega F, Gheysens O, Voigt JU.

Circ Arrhythm Electrophysiol. 2019 May;12(5):e007224. doi: 10.1161/CIRCEP.118.007224.


Persistent Impairment in Cardiopulmonary Fitness after Breast Cancer Chemotherapy.

Foulkes SJ, Howden EJ, Bigaran A, Janssens K, Antill Y, Loi S, Claus P, Haykowsky MJ, Daly RM, Fraser SF, LA Gerche A.

Med Sci Sports Exerc. 2019 Aug;51(8):1573-1581. doi: 10.1249/MSS.0000000000001970.


Creation of the Fontan circulation in sheep: a survival model.

Van Puyvelde J, Rega F, Minami T, Claus P, Cools B, Gewillig M, Meyns B.

Interact Cardiovasc Thorac Surg. 2019 Jul 1;29(1):15-21. doi: 10.1093/icvts/ivz022.


Unsupervised respiratory signal extraction from ungated cardiac magnetic resonance imaging at rest and during exercise.

Novillo F, Van Eyndhoven S, Moeyersons J, Bogaert J, Claessen G, La Gerche A, Van Huffel S, Claus P.

Phys Med Biol. 2019 Mar 8;64(6):065001. doi: 10.1088/1361-6560/ab02cd.


Structure, function and resilience to desiccation of methanogenic microbial communities in temporarily inundated soils of the Amazon rainforest (Cunia Reserve, Rondonia).

Hernández M, Klose M, Claus P, Bastviken D, Marotta H, Figueiredo V, Enrich-Prast A, Conrad R.

Environ Microbiol. 2019 May;21(5):1702-1717. doi: 10.1111/1462-2920.14535. Epub 2019 Mar 19.


Partial volume and motion correction in cardiac PET: First results from an in vs ex vivo comparison using animal datasets.

Turco A, Gheysens O, Duchenne J, Nuyts J, Rega F, Voigt JU, Vunckx K, Claus P.

J Nucl Cardiol. 2019 Dec;26(6):2034-2044. doi: 10.1007/s12350-018-01581-z. Epub 2019 Jan 14.


Determinants of exercise intolerance in breast cancer patients prior to anthracycline chemotherapy.

Beaudry RI, Howden EJ, Foulkes S, Bigaran A, Claus P, Haykowsky MJ, Gerche A.

Physiol Rep. 2019 Jan;7(1):e13971. doi: 10.14814/phy2.13971.


Robust motion correction for cardiac T1 and ECV mapping using a T1 relaxation model approach.

Tilborghs S, Dresselaers T, Claus P, Claessen G, Bogaert J, Maes F, Suetens P.

Med Image Anal. 2019 Feb;52:212-227. doi: 10.1016/ Epub 2018 Dec 18.


Advanced Imaging to Phenotype Patients With a Systemic Right Ventricle.

Helsen F, Claus P, Van De Bruaene A, Claessen G, La Gerche A, De Meester P, Claeys M, Gabriels C, Petit T, Santens B, Troost E, Voigt JU, Bogaert J, Budts W.

J Am Heart Assoc. 2018 Oct 16;7(20):e009185. doi: 10.1161/JAHA.118.009185.


Myocyte Remodeling Due to Fibro-Fatty Infiltrations Influences Arrhythmogenicity.

De Coster T, Claus P, Seemann G, Willems R, Sipido KR, Panfilov AV.

Front Physiol. 2018 Oct 4;9:1381. doi: 10.3389/fphys.2018.01381. eCollection 2018.


Impaired Cardiac Reserve and Abnormal Vascular Load Limit Exercise Capacity in Chronic Thromboembolic Disease.

Claeys M, Claessen G, La Gerche A, Petit T, Belge C, Meyns B, Bogaert J, Willems R, Claus P, Delcroix M.

JACC Cardiovasc Imaging. 2019 Aug;12(8 Pt 1):1444-1456. doi: 10.1016/j.jcmg.2018.07.021. Epub 2018 Sep 12.


Gene expression profiles in neurological tissues during West Nile virus infection: a critical meta-analysis.

Kosch R, Delarocque J, Claus P, Becker SC, Jung K.

BMC Genomics. 2018 Jul 13;19(1):530. doi: 10.1186/s12864-018-4914-4.


Light modulation ameliorates expression of circadian genes and disease progression in spinal muscular atrophy mice.

Walter LM, Koch CE, Betts CA, Ahlskog N, Meijboom KE, van Westering TLE, Hazell G, Bhomra A, Claus P, Oster H, Wood MJA, Bowerman M.

Hum Mol Genet. 2018 Oct 15;27(20):3582-3597. doi: 10.1093/hmg/ddy249.


Safety and Efficacy of Intracoronary Infusion of Allogeneic Human Cardiac Stem Cells in Patients With ST-Segment Elevation Myocardial Infarction and Left Ventricular Dysfunction.

Fernández-Avilés F, Sanz-Ruiz R, Bogaert J, Casado Plasencia A, Gilaberte I, Belmans A, Fernández-Santos ME, Charron D, Mulet M, Yotti R, Palacios I, Luque M, Sádaba R, San Román JA, Larman M, Sánchez PL, Sanchís J, Jiménez MF, Claus P, Al-Daccak R, Lombardo E, Abad JL, DelaRosa O, Corcóstegui L, Bermejo J, Janssens S.

Circ Res. 2018 Aug 17;123(5):579-589. doi: 10.1161/CIRCRESAHA.118.312823.


Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals.

Balek L, Buchtova M, Kunova Bosakova M, Varecha M, Foldynova-Trantirkova S, Gudernova I, Vesela I, Havlik J, Neburkova J, Turner S, Krzyscik MA, Zakrzewska M, Klimaschewski L, Claus P, Trantirek L, Cigler P, Krejci P.

Biomaterials. 2018 Sep;176:106-121. doi: 10.1016/j.biomaterials.2018.05.030. Epub 2018 May 21.


Left ventricular global myocardial strain assessment comparing the reproducibility of four commercially available CMR-feature tracking algorithms.

Barreiro-Pérez M, Curione D, Symons R, Claus P, Voigt JU, Bogaert J.

Eur Radiol. 2018 Dec;28(12):5137-5147. doi: 10.1007/s00330-018-5538-4. Epub 2018 Jun 5.


Nitric oxide for inhalation in ST-elevation myocardial infarction (NOMI): a multicentre, double-blind, randomized controlled trial.

Janssens SP, Bogaert J, Zalewski J, Toth A, Adriaenssens T, Belmans A, Bennett J, Claus P, Desmet W, Dubois C, Goetschalckx K, Sinnaeve P, Vandenberghe K, Vermeersch P, Lux A, Szelid Z, Durak M, Lech P, Zmudka K, Pokreisz P, Vranckx P, Merkely B, Bloch KD, Van de Werf F; NOMI investigators.

Eur Heart J. 2018 Aug 1;39(29):2717-2725. doi: 10.1093/eurheartj/ehy232.


Lemierre's syndrome: a case study with a short review of literature.

De Smet K, Claus PE, Alliet G, Simpelaere A, Desmet G.

Acta Clin Belg. 2019 Jun;74(3):206-210. doi: 10.1080/17843286.2018.1474614. Epub 2018 May 21. Review.


Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice.

Walter LM, Deguise MO, Meijboom KE, Betts CA, Ahlskog N, van Westering TLE, Hazell G, McFall E, Kordala A, Hammond SM, Abendroth F, Murray LM, Shorrock HK, Prosdocimo DA, Haldar SM, Jain MK, Gillingwater TH, Claus P, Kothary R, Wood MJA, Bowerman M.

EBioMedicine. 2018 May;31:226-242. doi: 10.1016/j.ebiom.2018.04.024. Epub 2018 May 4.


Hyperactive ryanodine receptors in human heart failure and ischaemic cardiomyopathy reside outside of couplons.

Dries E, Santiago DJ, Gilbert G, Lenaerts I, Vandenberk B, Nagaraju CK, Johnson DM, Holemans P, Roderick HL, Macquaide N, Claus P, Sipido KR.

Cardiovasc Res. 2018 Sep 1;114(11):1512-1524. doi: 10.1093/cvr/cvy088.


Intact interleukin-10 receptor signaling protects from hippocampal damage elicited by experimental neurotropic virus infection of SJL mice.

Uhde AK, Ciurkiewicz M, Herder V, Khan MA, Hensel N, Claus P, Beckstette M, Teich R, Floess S, Baumgärtner W, Jung K, Huehn J, Beineke A.

Sci Rep. 2018 Apr 17;8(1):6106. doi: 10.1038/s41598-018-24378-z.


Exercise cardiac magnetic resonance to differentiate athlete's heart from structural heart disease.

Claessen G, Schnell F, Bogaert J, Claeys M, Pattyn N, De Buck F, Dymarkowski S, Claus P, Carré F, Van Cleemput J, La Gerche A, Heidbuchel H.

Eur Heart J Cardiovasc Imaging. 2018 Sep 1;19(9):1062-1070. doi: 10.1093/ehjci/jey050.


Papillary muscles contribute significantly more to left ventricular work in dilated hearts.

Duchenne J, Turco A, Bézy S, Ünlü S, Pagourelias ED, Beela AS, Degtiarova G, Vunckx K, Nuyts J, Coudyzer W, Claus P, Rega F, Gheysens O, Voigt JU.

Eur Heart J Cardiovasc Imaging. 2019 Jan 1;20(1):84-91. doi: 10.1093/ehjci/jey043.


Sheep can be used as animal model of regional myocardial remodeling and controllable work.

Duchenne J, Claus P, Pagourelias ED, Mada RO, Van Puyvelde J, Vunckx K, Verbeken E, Gheysens O, Rega F, Voigt JU.

Cardiol J. 2019;26(4):375-384. doi: 10.5603/CJ.a2018.0007. Epub 2018 Mar 23.


Hyperbaric oxygen as a treatment modality in cyclophosphamide-induced hemorrhagic cystitis.

Kaur D, Khan SP, Rodriguez V, Arndt C, Claus P.

Pediatr Transplant. 2018 Jun;22(4):e13171. doi: 10.1111/petr.13171. Epub 2018 Mar 23.


Right ventricular systolic dysfunction at rest is not related to decreased exercise capacity in patients with a systemic right ventricle.

Helsen F, De Meester P, Van De Bruaene A, Gabriels C, Santens B, Claeys M, Claessen G, Goetschalckx K, Buys R, Gewillig M, Troost E, Voigt JU, Claus P, Bogaert J, Budts W.

Int J Cardiol. 2018 Jun 1;260:66-71. doi: 10.1016/j.ijcard.2018.03.029. Epub 2018 Mar 8.


Quantitative and qualitative assessment of acute myocardial injury by CMR at multiple time points after acute myocardial infarction.

Symons R, Claus P, Marchi A, Dresselaers T, Bogaert J.

Int J Cardiol. 2018 May 15;259:43-46. doi: 10.1016/j.ijcard.2018.02.093. Epub 2018 Feb 25.


Ascaris lumbricoides: challenges in diagnosis, treatment and prevention strategies in a European refugee camp.

Claus PE, Ceuppens AS, Cool M, Alliet G.

Acta Clin Belg. 2018 Dec;73(6):431-434. doi: 10.1080/17843286.2018.1436956. Epub 2018 Feb 19.


Hyperbaric oxygen therapy is well tolerated and effective for ulcerative colitis patients hospitalized for moderate-severe flares: a phase 2A pilot multi-center, randomized, double-blind, sham-controlled trial.

Dulai PS, Buckey JC Jr, Raffals LE, Swoger JM, Claus PL, OʼToole K, Ptak JA, Gleeson MW, Widjaja CE, Chang JT, Adler JM, Patel N, Skinner LA, Haren SP, Goldby-Reffner K, Thompson KD, Siegel CA.

Am J Gastroenterol. 2018 Oct;113(10):1516-1523. doi: 10.1038/s41395-018-0005-z. Epub 2018 Feb 16.


Arrhythmogenicity of fibro-fatty infiltrations.

De Coster T, Claus P, Kazbanov IV, Haemers P, Willems R, Sipido KR, Panfilov AV.

Sci Rep. 2018 Feb 1;8(1):2050. doi: 10.1038/s41598-018-20450-w.


Atrial volume and function during exercise in health and disease.

Schnell F, Claessen G, La Gerche A, Claus P, Bogaert J, Delcroix M, Carré F, Heidbuchel H.

J Cardiovasc Magn Reson. 2017 Dec 18;19(1):104. doi: 10.1186/s12968-017-0416-9.


Low-flow support of the chronic pressure-overloaded right ventricle induces reversed remodeling.

Verbelen T, Claus P, Burkhoff D, Driesen RB, Kadur Nagaraju C, Verbeken E, Sipido K, Delcroix M, Rega F, Meyns B.

J Heart Lung Transplant. 2018 Jan;37(1):151-160. doi: 10.1016/j.healun.2017.09.014. Epub 2017 Sep 29.


Metalloprotease-mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA).

Rademacher S, Verheijen BM, Hensel N, Peters M, Bora G, Brandes G, Vieira de Sá R, Heidrich N, Fischer S, Brinkmann H, van der Pol WL, Wirth B, Pasterkamp RJ, Claus P.

Hum Mol Genet. 2017 Oct 15;26(20):3946-3959. doi: 10.1093/hmg/ddx282.


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