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scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation.

Madissoon E, Wilbrey-Clark A, Miragaia RJ, Saeb-Parsy K, Mahbubani KT, Georgakopoulos N, Harding P, Polanski K, Huang N, Nowicki-Osuch K, Fitzgerald RC, Loudon KW, Ferdinand JR, Clatworthy MR, Tsingene A, van Dongen S, Dabrowska M, Patel M, Stubbington MJT, Teichmann SA, Stegle O, Meyer KB.

Genome Biol. 2019 Dec 31;21(1):1. doi: 10.1186/s13059-019-1906-x.


Using single-cell technologies to map the human immune system - implications for nephrology.

Stewart BJ, Ferdinand JR, Clatworthy MR.

Nat Rev Nephrol. 2019 Dec 12. doi: 10.1038/s41581-019-0227-3. [Epub ahead of print] Review.


Risk Factors for Revision Anterior Cruciate Ligament Reconstruction and Frequency With Which Patients Change Surgeons.

Sutherland K, Clatworthy M, Chang K, Rahardja R, Young SW.

Orthop J Sports Med. 2019 Nov 21;7(11):2325967119880487. doi: 10.1177/2325967119880487. eCollection 2019 Nov.


Effect of Graft Choice on Revision and Contralateral Anterior Cruciate Ligament Reconstruction: Results From the New Zealand ACL Registry.

Rahardja R, Zhu M, Love H, Clatworthy MG, Monk AP, Young SW.

Am J Sports Med. 2020 Jan;48(1):63-69. doi: 10.1177/0363546519885148. Epub 2019 Nov 15.


Rates of revision and surgeon-reported graft rupture following ACL reconstruction: early results from the New Zealand ACL Registry.

Rahardja R, Zhu M, Love H, Clatworthy MG, Monk AP, Young SW.

Knee Surg Sports Traumatol Arthrosc. 2019 Nov 3. doi: 10.1007/s00167-019-05773-z. [Epub ahead of print]


Spatiotemporal immune zonation of the human kidney.

Stewart BJ, Ferdinand JR, Young MD, Mitchell TJ, Loudon KW, Riding AM, Richoz N, Frazer GL, Staniforth JUL, Vieira Braga FA, Botting RA, Popescu DM, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Polanski K, Efremova M, Green K, Del Castillo Velasco-Herrera M, Guzzo C, Collord G, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Lindsay S, Bajenoff M, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Behjati S, Clatworthy MR.

Science. 2019 Sep 27;365(6460):1461-1466. doi: 10.1126/science.aat5031.


Phenotypically distinct neutrophils patrol uninfected human and mouse lymph nodes.

Lok LSC, Dennison TW, Mahbubani KM, Saeb-Parsy K, Chilvers ER, Clatworthy MR.

Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19083-19089. doi: 10.1073/pnas.1905054116. Epub 2019 Sep 4.


Mucosal IgG in inflammatory bowel disease - a question of (sub)class?

Castro-Dopico T, Clatworthy MR.

Gut Microbes. 2019 Sep 3:1-9. doi: 10.1080/19490976.2019.1651596. [Epub ahead of print]


Marked increase in the incidence of anterior cruciate ligament reconstructions in young females in New Zealand.

Sutherland K, Clatworthy M, Fulcher M, Chang K, Young SW.

ANZ J Surg. 2019 Sep;89(9):1151-1155. doi: 10.1111/ans.15404. Epub 2019 Aug 26.


B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses.

Bagchi-Chakraborty J, Francis A, Bray T, Masters L, Tsiantoulas D, Nus M, Harrison J, Broekhuizen M, Leggat J, Clatworthy MR, Espéli M, Smith KGC, Binder CJ, Mallat Z, Sage AP.

Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1379-1389. doi: 10.1161/ATVBAHA.118.312272. Epub 2019 May 16.


IgG and Fcγ Receptors in Intestinal Immunity and Inflammation.

Castro-Dopico T, Clatworthy MR.

Front Immunol. 2019 Apr 12;10:805. doi: 10.3389/fimmu.2019.00805. eCollection 2019. Review.


HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.

Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand JR, Simon M, Bär AL, Brochhausen C, Gerlach RG, Tomiuk S, Hammer K, Wagner S, van Zandbergen G, Binger KJ, Müller DN, Kitada K, Clatworthy MR, Kurts C, Titze J, Abdullah Z, Jantsch J.

Autophagy. 2019 Nov;15(11):1899-1916. doi: 10.1080/15548627.2019.1596483. Epub 2019 Apr 14.


How to Find a Resident Kidney Macrophage: the Single-Cell Sequencing Solution.

Clatworthy MR.

J Am Soc Nephrol. 2019 May;30(5):715-716. doi: 10.1681/ASN.2019030245. Epub 2019 Apr 4. No abstract available.


Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.

Castro-Dopico T, Dennison TW, Ferdinand JR, Mathews RJ, Fleming A, Clift D, Stewart BJ, Jing C, Strongili K, Labzin LI, Monk EJM, Saeb-Parsy K, Bryant CE, Clare S, Parkes M, Clatworthy MR.

Immunity. 2019 Apr 16;50(4):1099-1114.e10. doi: 10.1016/j.immuni.2019.02.006. Epub 2019 Mar 12.


The influence of tibial slope on anterior cruciate ligament graft failure risk is dependent on graft positioning.

Sauer S, English R, Clatworthy M.

J Orthop Surg (Hong Kong). 2019 Jan-Apr;27(1):2309499019834674. doi: 10.1177/2309499019834674.


Belimumab in kidney transplantation - Authors' reply.

Banham GD, Flint SM, Shanahan DN, Henderson RB, Clatworthy MR.

Lancet. 2019 Mar 2;393(10174):875-876. doi: 10.1016/S0140-6736(18)33066-6. No abstract available.


Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo.

Booty LM, Gawel JM, Cvetko F, Caldwell ST, Hall AR, Mulvey JF, James AM, Hinchy EC, Prime TA, Arndt S, Beninca C, Bright TP, Clatworthy MR, Ferdinand JR, Prag HA, Logan A, Prudent J, Krieg T, Hartley RC, Murphy MP.

Cell Chem Biol. 2019 Mar 21;26(3):449-461.e8. doi: 10.1016/j.chembiol.2018.12.002. Epub 2019 Jan 31.


Monocyte Function in Parkinson's Disease and the Impact of Autologous Serum on Phagocytosis.

Wijeyekoon RS, Kronenberg-Versteeg D, Scott KM, Hayat S, Jones JL, Clatworthy MR, Floto RA, Barker RA, Williams-Gray CH.

Front Neurol. 2018 Oct 16;9:870. doi: 10.3389/fneur.2018.00870. eCollection 2018.


A Systematic Review and Meta-Analysis of Alpha Synuclein Auto-Antibodies in Parkinson's Disease.

Scott KM, Kouli A, Yeoh SL, Clatworthy MR, Williams-Gray CH.

Front Neurol. 2018 Oct 1;9:815. doi: 10.3389/fneur.2018.00815. eCollection 2018.


A randomized prospective study comparing mobile-bearing against fixed-bearing PFC Sigma cruciate-retaining total knee arthroplasties with ten-year minimum follow-up.

Powell AJ, Crua E, Chong BC, Gordon R, McAuslan A, Pitto RP, Clatworthy MG.

Bone Joint J. 2018 Oct;100-B(10):1336-1344. doi: 10.1302/0301-620X.100B10.BJJ-2017-1450.R1.


The Effect of Medial Tibial Slope on Anterior Tibial Translation and Short-Term ACL Reconstruction Outcome.

Sauer S, Clatworthy M.

Surg J (N Y). 2018 Sep 10;4(3):e160-e163. doi: 10.1055/s-0038-1669929. eCollection 2018 Jul.


The Ratio of Tibial Slope and Meniscal Bone Angle for the Prediction of ACL Reconstruction Failure Risk.

Sauer S, English R, Clatworthy M.

Surg J (N Y). 2018 Aug 20;4(3):e152-e159. doi: 10.1055/s-0038-1668111. eCollection 2018 Jul.


PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner.

Stark AK, Chandra A, Chakraborty K, Alam R, Carbonaro V, Clark J, Sriskantharajah S, Bradley G, Richter AG, Banham-Hall E, Clatworthy MR, Nejentsev S, Hamblin JN, Hessel EM, Condliffe AM, Okkenhaug K.

Nat Commun. 2018 Aug 9;9(1):3174. doi: 10.1038/s41467-018-05674-8.


Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.

Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S.

Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699.


Allograft rejection is associated with development of functional IgE specific for donor MHC antigens.

Farkas AM, Baranyi U, Böhmig GA, Unger L, Hopf S, Wahrmann M, Regele H, Mahr B, Schwarz C, Hock K, Pilat N, Kristo I, Mraz J, Lupinek C, Thalhamer J, Bond G, Kuessel L, Wlodek E, Martin J, Clatworthy M, Pettigrew G, Valenta R, Wekerle T.

J Allergy Clin Immunol. 2019 Jan;143(1):335-345.e12. doi: 10.1016/j.jaci.2018.06.034. Epub 2018 Aug 9.


Transportal central femoral tunnel placement has a significantly higher revision rate than transtibial AM femoral tunnel placement in hamstring ACL reconstruction.

Clatworthy M, Sauer S, Roberts T.

Knee Surg Sports Traumatol Arthrosc. 2019 Jan;27(1):124-129. doi: 10.1007/s00167-018-5036-x. Epub 2018 Jul 12.


Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.

Banham GD, Flint SM, Torpey N, Lyons PA, Shanahan DN, Gibson A, Watson CJE, O'Sullivan AM, Chadwick JA, Foster KE, Jones RB, Devey LR, Richards A, Erwig LP, Savage CO, Smith KGC, Henderson RB, Clatworthy MR.

Lancet. 2018 Jun 30;391(10140):2619-2630. doi: 10.1016/S0140-6736(18)30984-X. Epub 2018 Jun 14.


Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.

Benson RA, Garcon F, Recino A, Ferdinand JR, Clatworthy MR, Waldmann H, Brewer JM, Okkenhaug K, Cooke A, Garside P, Wållberg M.

Front Immunol. 2018 May 18;9:1006. doi: 10.3389/fimmu.2018.01006. eCollection 2018.


Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study.

Hernandez-Fuentes MP, Franklin C, Rebollo-Mesa I, Mollon J, Delaney F, Perucha E, Stapleton C, Borrows R, Byrne C, Cavalleri G, Clarke B, Clatworthy M, Feehally J, Fuggle S, Gagliano SA, Griffin S, Hammad A, Higgins R, Jardine A, Keogan M, Leach T, MacPhee I, Mark PB, Marsh J, Maxwell P, McKane W, McLean A, Newstead C, Augustine T, Phelan P, Powis S, Rowe P, Sheerin N, Solomon E, Stephens H, Thuraisingham R, Trembath R, Topham P, Vaughan R, Sacks SH, Conlon P, Opelz G, Soranzo N, Weale ME, Lord GM; United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3.

Am J Transplant. 2018 Jun;18(6):1370-1379. doi: 10.1111/ajt.14594. Epub 2018 Feb 1.


The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.


Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.

Berry MR, Mathews RJ, Ferdinand JR, Jing C, Loudon KW, Wlodek E, Dennison TW, Kuper C, Neuhofer W, Clatworthy MR.

Cell. 2017 Aug 24;170(5):860-874.e19. doi: 10.1016/j.cell.2017.07.022. Epub 2017 Aug 10.


Pancreatic allograft thrombosis: Suggestion for a CT grading system and management algorithm.

Hakeem A, Chen J, Iype S, Clatworthy MR, Watson CJE, Godfrey EM, Upponi S, Saeb-Parsy K.

Am J Transplant. 2018 Jan;18(1):163-179. doi: 10.1111/ajt.14433. Epub 2017 Sep 14.


Donors With Immune Thrombocytopenia: Do They Pose a Risk to Transplant Recipients?

Trotter PB, Robb M, Summers D, Watson CJ, Clatworthy M, Bradley JA, Hill QA, Neuberger J.

Am J Transplant. 2017 Mar;17(3):796-802. doi: 10.1111/ajt.14105. Epub 2016 Dec 9.


Fcγ Receptors in Solid Organ Transplantation.

Castro-Dopico T, Clatworthy MR.

Curr Transplant Rep. 2016;3(4):284-293. Epub 2016 Oct 3. Review.


Kidney Macrophages: Unique Position Solves a Complex Problem.

Berry M, Clatworthy MR.

Cell. 2016 Aug 11;166(4):799-801. doi: 10.1016/j.cell.2016.07.047.


Local Expansion of Donation After Circulatory Death Kidney Transplant Activity Improves Waitlisted Outcomes and Addresses Inequities of Access to Transplantation.

Mirshekar-Syahkal B, Summers D, Bradbury LL, Aly M, Bardsley V, Berry M, Norris JM, Torpey N, Clatworthy MR, Bradley JA, Pettigrew GJ.

Am J Transplant. 2017 Feb;17(2):390-400. doi: 10.1111/ajt.13968. Epub 2016 Aug 26.


Novel immunotherapeutic strategies to target alloantibody-producing B and plasma cells in transplantation.

Inaba A, Clatworthy MR.

Curr Opin Organ Transplant. 2016 Aug;21(4):419-26. doi: 10.1097/MOT.0000000000000338. Review.


Total Knee Replacement Plus Nonsurgical Treatment Was Better Than Nonsurgical Treatment Alone for Knee Osteoarthritis.

Clatworthy M.

J Bone Joint Surg Am. 2016 May 18;98(10):873. doi: 10.2106/JBJS.16.00208. No abstract available.


Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant.

Harper IG, Ali JM, Harper SJ, Wlodek E, Alsughayyir J, Negus MC, Qureshi MS, Motalleb-Zadeh R, Saeb-Parsy K, Bolton EM, Bradley JA, Clatworthy MR, Conlon TM, Pettigrew GJ.

Cell Rep. 2016 May 10;15(6):1214-27. doi: 10.1016/j.celrep.2016.04.009. Epub 2016 Apr 28.


B cells in transplantation.

Dijke EI, Platt JL, Blair P, Clatworthy MR, Patel JK, Kfoury AG, Cascalho M.

J Heart Lung Transplant. 2016 Jun;35(6):704-10. doi: 10.1016/j.healun.2016.01.1232. Epub 2016 Feb 12.


FcγRIIB and autoimmunity.

Espéli M, Smith KG, Clatworthy MR.

Immunol Rev. 2016 Jan;269(1):194-211. doi: 10.1111/imr.12368. Review.


Does Computer Assisted Navigation Improve Functional Outcomes and Implant Survivability after Total Knee Arthroplasty?

Roberts TD, Clatworthy MG, Frampton CM, Young SW.

J Arthroplasty. 2015 Sep;30(9 Suppl):59-63. doi: 10.1016/j.arth.2014.12.036. Epub 2015 Jun 3.


Two-photon microscopy for imaging germinal centers and T follicular helper cells.

Clatworthy MR.

Methods Mol Biol. 2015;1291:63-75. doi: 10.1007/978-1-4939-2498-1_6.


B-cell biomarkers in transplantation--from genes to therapy.

Banham GD, Clatworthy MR.

Tissue Antigens. 2015 Feb;85(2):82-92. doi: 10.1111/tan.12520. Review.


B cell depletion at induction--making bad immunological memory fade?

Clatworthy MR.

Am J Transplant. 2015 Feb;15(2):297-8. doi: 10.1111/ajt.13054. No abstract available.


De-functioning polymorphism in the inhibitory receptor FcγRIIB does not impact upon kidney allograft survival.

Clatworthy MR, Matthews R, Doehler B, Willcocks L, Opelz G, Smith KG.

Clin Exp Immunol. 2014 Dec;178 Suppl 1:159-61. doi: 10.1111/cei.12553. No abstract available.


B cell modulation in transplantation.

Clatworthy MR.

Clin Exp Immunol. 2014 Dec;178 Suppl 1:61-3. doi: 10.1111/cei.12513. No abstract available.


FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.

Clatworthy MR, Harford SK, Mathews RJ, Smith KG.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17971-6. doi: 10.1073/pnas.1413915111. Epub 2014 Dec 4.


Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.

Clatworthy MR, Aronin CE, Mathews RJ, Morgan NY, Smith KG, Germain RN.

Nat Med. 2014 Dec;20(12):1458-63. doi: 10.1038/nm.3709. Epub 2014 Nov 10.


Psychometric Evaluation Of The Patient's Knee Implant Performance (PKIP) Questionnaire For The Assessment Of Primary Total Knee Arthroplasty.

Coles TM, Dwyer KA, Mordin M, Williams V, Clatworthy M, Yates P, Hamilton W.

Value Health. 2014 Nov;17(7):A568. doi: 10.1016/j.jval.2014.08.1895. Epub 2014 Oct 26. No abstract available.

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