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Items: 1 to 50 of 95

1.

Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo.

Booty LM, Gawel JM, Cvetko F, Caldwell ST, Hall AR, Mulvey JF, James AM, Hinchy EC, Prime TA, Arndt S, Beninca C, Bright TP, Clatworthy MR, Ferdinand JR, Prag HA, Logan A, Prudent J, Krieg T, Hartley RC, Murphy MP.

Cell Chem Biol. 2018 Dec 18. pii: S2451-9456(18)30440-9. doi: 10.1016/j.chembiol.2018.12.002. [Epub ahead of print]

2.

Monocyte Function in Parkinson's Disease and the Impact of Autologous Serum on Phagocytosis.

Wijeyekoon RS, Kronenberg-Versteeg D, Scott KM, Hayat S, Jones JL, Clatworthy MR, Floto RA, Barker RA, Williams-Gray CH.

Front Neurol. 2018 Oct 16;9:870. doi: 10.3389/fneur.2018.00870. eCollection 2018.

3.

A Systematic Review and Meta-Analysis of Alpha Synuclein Auto-Antibodies in Parkinson's Disease.

Scott KM, Kouli A, Yeoh SL, Clatworthy MR, Williams-Gray CH.

Front Neurol. 2018 Oct 1;9:815. doi: 10.3389/fneur.2018.00815. eCollection 2018.

4.

A randomized prospective study comparing mobile-bearing against fixed-bearing PFC Sigma cruciate-retaining total knee arthroplasties with ten-year minimum follow-up.

Powell AJ, Crua E, Chong BC, Gordon R, McAuslan A, Pitto RP, Clatworthy MG.

Bone Joint J. 2018 Oct;100-B(10):1336-1344. doi: 10.1302/0301-620X.100B10.BJJ-2017-1450.R1.

PMID:
30295539
5.

The Effect of Medial Tibial Slope on Anterior Tibial Translation and Short-Term ACL Reconstruction Outcome.

Sauer S, Clatworthy M.

Surg J (N Y). 2018 Sep 10;4(3):e160-e163. doi: 10.1055/s-0038-1669929. eCollection 2018 Jul.

6.

The Ratio of Tibial Slope and Meniscal Bone Angle for the Prediction of ACL Reconstruction Failure Risk.

Sauer S, English R, Clatworthy M.

Surg J (N Y). 2018 Aug 20;4(3):e152-e159. doi: 10.1055/s-0038-1668111. eCollection 2018 Jul.

7.

PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner.

Stark AK, Chandra A, Chakraborty K, Alam R, Carbonaro V, Clark J, Sriskantharajah S, Bradley G, Richter AG, Banham-Hall E, Clatworthy MR, Nejentsev S, Hamblin JN, Hessel EM, Condliffe AM, Okkenhaug K.

Nat Commun. 2018 Aug 9;9(1):3174. doi: 10.1038/s41467-018-05674-8.

8.

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.

Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S.

Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699.

PMID:
30093597
9.

Allograft rejection is associated with development of functional IgE specific for donor MHC antigens.

Farkas AM, Baranyi U, Böhmig GA, Unger L, Hopf S, Wahrmann M, Regele H, Mahr B, Schwarz C, Hock K, Pilat N, Kristo I, Mraz J, Lupinek C, Thalhamer J, Bond G, Kuessel L, Wlodek E, Martin J, Clatworthy M, Pettigrew G, Valenta R, Wekerle T.

J Allergy Clin Immunol. 2019 Jan;143(1):335-345.e12. doi: 10.1016/j.jaci.2018.06.034. Epub 2018 Aug 9.

10.

Transportal central femoral tunnel placement has a significantly higher revision rate than transtibial AM femoral tunnel placement in hamstring ACL reconstruction.

Clatworthy M, Sauer S, Roberts T.

Knee Surg Sports Traumatol Arthrosc. 2018 Jul 12. doi: 10.1007/s00167-018-5036-x. [Epub ahead of print]

PMID:
30003286
11.

Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.

Banham GD, Flint SM, Torpey N, Lyons PA, Shanahan DN, Gibson A, Watson CJE, O'Sullivan AM, Chadwick JA, Foster KE, Jones RB, Devey LR, Richards A, Erwig LP, Savage CO, Smith KGC, Henderson RB, Clatworthy MR.

Lancet. 2018 Jun 30;391(10140):2619-2630. doi: 10.1016/S0140-6736(18)30984-X. Epub 2018 Jun 14.

PMID:
29910042
12.

Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.

Benson RA, Garcon F, Recino A, Ferdinand JR, Clatworthy MR, Waldmann H, Brewer JM, Okkenhaug K, Cooke A, Garside P, Wållberg M.

Front Immunol. 2018 May 18;9:1006. doi: 10.3389/fimmu.2018.01006. eCollection 2018.

13.

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study.

Hernandez-Fuentes MP, Franklin C, Rebollo-Mesa I, Mollon J, Delaney F, Perucha E, Stapleton C, Borrows R, Byrne C, Cavalleri G, Clarke B, Clatworthy M, Feehally J, Fuggle S, Gagliano SA, Griffin S, Hammad A, Higgins R, Jardine A, Keogan M, Leach T, MacPhee I, Mark PB, Marsh J, Maxwell P, McKane W, McLean A, Newstead C, Augustine T, Phelan P, Powis S, Rowe P, Sheerin N, Solomon E, Stephens H, Thuraisingham R, Trembath R, Topham P, Vaughan R, Sacks SH, Conlon P, Opelz G, Soranzo N, Weale ME, Lord GM; United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3.

Am J Transplant. 2018 Jun;18(6):1370-1379. doi: 10.1111/ajt.14594. Epub 2018 Feb 1.

14.

The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.

15.

Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.

Berry MR, Mathews RJ, Ferdinand JR, Jing C, Loudon KW, Wlodek E, Dennison TW, Kuper C, Neuhofer W, Clatworthy MR.

Cell. 2017 Aug 24;170(5):860-874.e19. doi: 10.1016/j.cell.2017.07.022. Epub 2017 Aug 10.

16.

Pancreatic allograft thrombosis: Suggestion for a CT grading system and management algorithm.

Hakeem A, Chen J, Iype S, Clatworthy MR, Watson CJE, Godfrey EM, Upponi S, Saeb-Parsy K.

Am J Transplant. 2018 Jan;18(1):163-179. doi: 10.1111/ajt.14433. Epub 2017 Sep 14.

17.

Donors With Immune Thrombocytopenia: Do They Pose a Risk to Transplant Recipients?

Trotter PB, Robb M, Summers D, Watson CJ, Clatworthy M, Bradley JA, Hill QA, Neuberger J.

Am J Transplant. 2017 Mar;17(3):796-802. doi: 10.1111/ajt.14105. Epub 2016 Dec 9.

18.

Fcγ Receptors in Solid Organ Transplantation.

Castro-Dopico T, Clatworthy MR.

Curr Transplant Rep. 2016;3(4):284-293. Epub 2016 Oct 3. Review.

19.

Kidney Macrophages: Unique Position Solves a Complex Problem.

Berry M, Clatworthy MR.

Cell. 2016 Aug 11;166(4):799-801. doi: 10.1016/j.cell.2016.07.047.

20.

Local Expansion of Donation After Circulatory Death Kidney Transplant Activity Improves Waitlisted Outcomes and Addresses Inequities of Access to Transplantation.

Mirshekar-Syahkal B, Summers D, Bradbury LL, Aly M, Bardsley V, Berry M, Norris JM, Torpey N, Clatworthy MR, Bradley JA, Pettigrew GJ.

Am J Transplant. 2017 Feb;17(2):390-400. doi: 10.1111/ajt.13968. Epub 2016 Aug 26.

21.

Novel immunotherapeutic strategies to target alloantibody-producing B and plasma cells in transplantation.

Inaba A, Clatworthy MR.

Curr Opin Organ Transplant. 2016 Aug;21(4):419-26. doi: 10.1097/MOT.0000000000000338. Review.

PMID:
27262143
22.

Total Knee Replacement Plus Nonsurgical Treatment Was Better Than Nonsurgical Treatment Alone for Knee Osteoarthritis.

Clatworthy M.

J Bone Joint Surg Am. 2016 May 18;98(10):873. doi: 10.2106/JBJS.16.00208. No abstract available.

PMID:
27194500
23.

Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant.

Harper IG, Ali JM, Harper SJ, Wlodek E, Alsughayyir J, Negus MC, Qureshi MS, Motalleb-Zadeh R, Saeb-Parsy K, Bolton EM, Bradley JA, Clatworthy MR, Conlon TM, Pettigrew GJ.

Cell Rep. 2016 May 10;15(6):1214-27. doi: 10.1016/j.celrep.2016.04.009. Epub 2016 Apr 28.

24.

B cells in transplantation.

Dijke EI, Platt JL, Blair P, Clatworthy MR, Patel JK, Kfoury AG, Cascalho M.

J Heart Lung Transplant. 2016 Jun;35(6):704-10. doi: 10.1016/j.healun.2016.01.1232. Epub 2016 Feb 12.

25.

FcγRIIB and autoimmunity.

Espéli M, Smith KG, Clatworthy MR.

Immunol Rev. 2016 Jan;269(1):194-211. doi: 10.1111/imr.12368. Review.

PMID:
26683154
26.

Does Computer Assisted Navigation Improve Functional Outcomes and Implant Survivability after Total Knee Arthroplasty?

Roberts TD, Clatworthy MG, Frampton CM, Young SW.

J Arthroplasty. 2015 Sep;30(9 Suppl):59-63. doi: 10.1016/j.arth.2014.12.036. Epub 2015 Jun 3.

PMID:
26138516
27.

Two-photon microscopy for imaging germinal centers and T follicular helper cells.

Clatworthy MR.

Methods Mol Biol. 2015;1291:63-75. doi: 10.1007/978-1-4939-2498-1_6.

PMID:
25836302
28.

B-cell biomarkers in transplantation--from genes to therapy.

Banham GD, Clatworthy MR.

Tissue Antigens. 2015 Feb;85(2):82-92. doi: 10.1111/tan.12520. Review.

PMID:
25626600
29.

B cell depletion at induction--making bad immunological memory fade?

Clatworthy MR.

Am J Transplant. 2015 Feb;15(2):297-8. doi: 10.1111/ajt.13054. No abstract available.

30.

De-functioning polymorphism in the inhibitory receptor FcγRIIB does not impact upon kidney allograft survival.

Clatworthy MR, Matthews R, Doehler B, Willcocks L, Opelz G, Smith KG.

Clin Exp Immunol. 2014 Dec;178 Suppl 1:159-61. doi: 10.1111/cei.12553. No abstract available.

31.

B cell modulation in transplantation.

Clatworthy MR.

Clin Exp Immunol. 2014 Dec;178 Suppl 1:61-3. doi: 10.1111/cei.12513. No abstract available.

32.

FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.

Clatworthy MR, Harford SK, Mathews RJ, Smith KG.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17971-6. doi: 10.1073/pnas.1413915111. Epub 2014 Dec 4.

33.

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.

Clatworthy MR, Aronin CE, Mathews RJ, Morgan NY, Smith KG, Germain RN.

Nat Med. 2014 Dec;20(12):1458-63. doi: 10.1038/nm.3709. Epub 2014 Nov 10.

34.

Psychometric Evaluation Of The Patient's Knee Implant Performance (PKIP) Questionnaire For The Assessment Of Primary Total Knee Arthroplasty.

Coles TM, Dwyer KA, Mordin M, Williams V, Clatworthy M, Yates P, Hamilton W.

Value Health. 2014 Nov;17(7):A568. doi: 10.1016/j.jval.2014.08.1895. Epub 2014 Oct 26. No abstract available.

35.

Genotoxins induce binucleation in L5178Y and TK6 cells.

Doherty AT, Wilson A, Chocian K, Molloy J, Clatworthy M, Doak S, Jenkins G, O'Donovan M.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Aug;770:29-34. doi: 10.1016/j.mrgentox.2014.05.005. Epub 2014 May 28.

PMID:
25344161
36.

Defunctioning polymorphism in the immunoglobulin G inhibitory receptor (FcγRIIB-T/T232) does not impact on kidney transplant or recipient survival.

Clatworthy MR, Matthews RJ, Doehler B, Willcocks LC, Opelz G, Smith KGC.

Transplantation. 2014 Aug 15;98(3):285-291. doi: 10.1097/TP.0000000000000287.

37.

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage.

Angulo I, Vadas O, Garçon F, Banham-Hall E, Plagnol V, Leahy TR, Baxendale H, Coulter T, Curtis J, Wu C, Blake-Palmer K, Perisic O, Smyth D, Maes M, Fiddler C, Juss J, Cilliers D, Markelj G, Chandra A, Farmer G, Kielkowska A, Clark J, Kracker S, Debré M, Picard C, Pellier I, Jabado N, Morris JA, Barcenas-Morales G, Fischer A, Stephens L, Hawkins P, Barrett JC, Abinun M, Clatworthy M, Durandy A, Doffinger R, Chilvers ER, Cant AJ, Kumararatne D, Okkenhaug K, Williams RL, Condliffe A, Nejentsev S.

Science. 2013 Nov 15;342(6160):866-71. doi: 10.1126/science.1243292. Epub 2013 Oct 17.

38.

B-cell regulation and its application to transplantation.

Clatworthy MR.

Transpl Int. 2014 Feb;27(2):117-28. doi: 10.1111/tri.12160. Epub 2013 Aug 4. Review.

39.

Elevated pretransplantation soluble BAFF is associated with an increased risk of acute antibody-mediated rejection.

Banham G, Prezzi D, Harford S, Taylor CJ, Hamer R, Higgins R, Bradley JA, Clatworthy MR.

Transplantation. 2013 Aug 27;96(4):413-20. doi: 10.1097/TP.0b013e318298dd65.

40.

B cell responses to allograft--more common than we thought?

Clatworthy MR.

Am J Transplant. 2013 Jul;13(7):1629-30. doi: 10.1111/ajt.12309. No abstract available.

41.

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.

Subramanian N, Natarajan K, Clatworthy MR, Wang Z, Germain RN.

Cell. 2013 Apr 11;153(2):348-61. doi: 10.1016/j.cell.2013.02.054.

42.

Applications of computer navigation in sports medicine knee surgery: an evidence-based review.

Young SW, Safran MR, Clatworthy M.

Curr Rev Musculoskelet Med. 2013 Jun;6(2):150-7. doi: 10.1007/s12178-013-9166-y.

43.

Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis.

Sánchez-Barrena MJ, Vallis Y, Clatworthy MR, Doherty GJ, Veprintsev DB, Evans PR, McMahon HT.

PLoS One. 2012;7(12):e52401. doi: 10.1371/journal.pone.0052401. Epub 2012 Dec 20. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/3bdc487b-5e25-4cd7-a354-b2952eec943d.

44.

Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.

Espéli M, Clatworthy MR, Bökers S, Lawlor KE, Cutler AJ, Köntgen F, Lyons PA, Smith KG.

J Exp Med. 2012 Nov 19;209(12):2307-19. doi: 10.1084/jem.20121752. Epub 2012 Oct 29.

45.

The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases.

Banham-Hall E, Clatworthy MR, Okkenhaug K.

Open Rheumatol J. 2012;6:245-58. doi: 10.2174/1874312901206010245. Epub 2012 Sep 7.

46.

Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis.

Clatworthy MR, Kettunen MI, Hu DE, Mathews RJ, Witney TH, Kennedy BW, Bohndiek SE, Gallagher FA, Jarvis LB, Smith KG, Brindle KM.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13374-9. doi: 10.1073/pnas.1205539109. Epub 2012 Jul 26.

47.

Preformed donor HLA-DP-specific antibodies mediate acute and chronic antibody-mediated rejection following renal transplantation.

Jolly EC, Key T, Rasheed H, Morgan H, Butler A, Pritchard N, Taylor CJ, Clatworthy MR.

Am J Transplant. 2012 Oct;12(10):2845-8. doi: 10.1111/j.1600-6143.2012.04172.x. Epub 2012 Jul 3.

48.

Immunotherapy for acute kidney injury.

Berry M, Clatworthy MR.

Immunotherapy. 2012 Mar;4(3):323-34. doi: 10.2217/imt.11.175. Review.

PMID:
22401637
49.

Targeting B cells and antibody in transplantation.

Clatworthy MR.

Am J Transplant. 2011 Jul;11(7):1359-67. doi: 10.1111/j.1600-6143.2011.03554.x. Epub 2011 Jun 10. Review.

50.

Fabry disease: results of the first UK hemodialysis screening study.

Wallin EF, Clatworthy MR, Pritchard NR.

Clin Nephrol. 2011 Jun;75(6):506-10.

PMID:
21612753

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