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The Dose and Timing of Fentanyl Impacts on Ticagrelor Absorption and Platelet Inhibition During Percutaneous Coronary Intervention: The PACIFY Randomized Clinical Trial.

Goli RR, Ibrahim K, Shah R, Kickler TS, Clarke WA, Resar JR, Schulman SP, McEvoy JW.

J Invasive Cardiol. 2019 Sep;31(9):265-271.


Colorectal cancer surveillance in inflammatory bowel disease: Practice guidelines and recent developments.

Clarke WT, Feuerstein JD.

World J Gastroenterol. 2019 Aug 14;25(30):4148-4157. doi: 10.3748/wjg.v25.i30.4148. Review.


Partially Wireless Pulse Oximetry Reduces Loss of Signal Integrity due to Motion in Children.

Petersen PC, Hanson S, Yan K, Clarke W.

Hosp Pediatr. 2019 Sep;9(9):690-696. doi: 10.1542/hpeds.2019-0017. Epub 2019 Aug 16.


Editorial: older patients are significantly more likely to have colon ischaemia-associated conditions that are chronic and complex.

Clarke WT, Feuerstein JD.

Aliment Pharmacol Ther. 2019 Aug;50(3):329-330. doi: 10.1111/apt.15287. No abstract available.


Metabolic syndrome and liver steatosis occur at lower body mass index in US Asian patients with chronic hepatitis B.

Clarke WT, Miranda J, Neidich E, Hudock R, Peters MG, Kelly EM.

J Viral Hepat. 2019 May 28. doi: 10.1111/jvh.13147. [Epub ahead of print]


An ultra-spatially resolved method to quali-quantitative monitor particulate matter in urban environment.

Baldacchini C, Sgrigna G, Clarke W, Tallis M, Calfapietra C.

Environ Sci Pollut Res Int. 2019 Jun;26(18):18719-18729. doi: 10.1007/s11356-019-05160-8. Epub 2019 May 4.


Reproducibility of human cardiac phosphorus MRS (31 P-MRS) at 7 T.

Ellis J, Valkovič L, Purvis LAB, Clarke WT, Rodgers CT.

NMR Biomed. 2019 Jun;32(6):e4095. doi: 10.1002/nbm.4095. Epub 2019 Mar 29.


Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T.

Clarke WT, Peterzan MA, Rayner JJ, Sayeed RA, Petrou M, Krasopoulos G, Lake HA, Raman B, Watson WD, Cox P, Hundertmark MJ, Apps AP, Lygate CA, Neubauer S, Rider OJ, Rodgers CT.

NMR Biomed. 2019 Jun;32(6):e4085. doi: 10.1002/nbm.4085. Epub 2019 Mar 28.


Antiretroviral adherence, elevated viral load and drug resistant mutations in HIV-infected women initiating treatment in pregnancy: a nested case-control study.

Myer L, Redd AD, Mukonda E, Lynch BA, Phillips TK, Eisenberg A, Hsiao NY, Capoferri A, Zerbe A, Clarke W, Lesosky M, Breaud A, McIntyre J, Bruno D, Martens C, Abrams EJ, Reynolds SJ.

Clin Infect Dis. 2019 Mar 16. pii: ciz209. doi: 10.1093/cid/ciz209. [Epub ahead of print]


Measuring inorganic phosphate and intracellular pH in the healthy and hypertrophic cardiomyopathy hearts by in vivo 7T 31P-cardiovascular magnetic resonance spectroscopy.

Valkovič L, Clarke WT, Schmid AI, Raman B, Ellis J, Watkins H, Robson MD, Neubauer S, Rodgers CT.

J Cardiovasc Magn Reson. 2019 Mar 14;21(1):19. doi: 10.1186/s12968-019-0529-4.


Glycoform Analysis of Alpha1-Acid Glycoprotein by Capillary Electrophoresis Using Electrophoretic Injection.

Zhang C, Clarke W, Hage DS.

Methods Mol Biol. 2019;1972:41-56. doi: 10.1007/978-1-4939-9213-3_4.


Signaling characteristics and functional regulation of delta opioid-kappa opioid receptor (DOP-KOP) heteromers in peripheral sensory neurons.

Jacobs BA, Pando MM, Jennings EM, Jamshidi RJ, Zamora JC, Chavera TS, Clarke WP, Berg KA.

Neuropharmacology. 2019 Jun;151:208-218. doi: 10.1016/j.neuropharm.2019.02.019. Epub 2019 Feb 15.


Use of Antiretroviral Drug Testing to Assess the Accuracy of Self-reported Data from HIV-Infected People Who Inject Drugs.

Fogel JM, Zhang Y, Palumbo PJ, Guo X, Clarke W, Breaud A, Richardson P, Piwowar-Manning E, Hamilton EL, Ha TV, Dumchev K, Djoerban Z, Hoffman I, Hanscom B, Miller WC, Eshleman SH.

AIDS Behav. 2019 Aug;23(8):2101-2108. doi: 10.1007/s10461-018-2379-8.


Natural control of HIV infection in young women in South Africa: HPTN 068.

Sivay MV, Fogel JM, Wang J, Zhang Y, Piwowar-Manning E, Clarke W, Breaud A, Blankson J, Hamilton EL, Kahn K, Selin A, Gomez-Olive FX, MacPhail C, Hughes JP, Pettifor A, Eshleman SH.

HIV Clin Trials. 2018 Oct;19(5):202-208. doi: 10.1080/15284336.2018.1531534. Epub 2018 Dec 6.


CLPTM1L/CRR9 ectodomain interaction with GRP78 at the cell surface signals for survival and chemoresistance upon ER stress in pancreatic adenocarcinoma cells.

Clarke WR, Amundadottir L, James MA.

Int J Cancer. 2019 Mar 15;144(6):1367-1378. doi: 10.1002/ijc.32012. Epub 2019 Jan 3.


Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015.

Moyo S, Gaseitsiwe S, Mohammed T, Pretorius Holme M, Wang R, Kotokwe KP, Boleo C, Mupfumi L, Yankinda EK, Chakalisa U, van Widenfelt E, Gaolathe T, Mmalane MO, Dryden-Peterson S, Mine M, Lebelonyane R, Bennett K, Leidner J, Wirth KE, Tchetgen Tchetgen E, Powis K, Moore J, Clarke WA, Lockman S, Makhema JM, Essex M, Novitsky V.

PLoS One. 2018 Oct 24;13(10):e0204840. doi: 10.1371/journal.pone.0204840. eCollection 2018.


Regional differences between people who inject drugs in an HIV prevention trial integrating treatment and prevention (HPTN 074): a baseline analysis.

Lancaster KE, Hoffman IF, Hanscom B, Ha TV, Dumchev K, Susami H, Rose S, Go VF, Reifeis SA, Mollan KR, Hudgens MG, Piwowar-Manning EM, Richardson P, Dvoriak S, Djoerban Z, Kiriazova T, Zeziulin O, Djauzi S, Ahn CV, Latkin C, Metzger D, Burns DN, Sugarman J, Strathdee SA, Eshleman SH, Clarke W, Donnell D, Emel L, Sunner LE, McKinstry L, Sista N, Hamilton EL, Lucas JP, Duong BD, Van Vuong N, Sarasvita R, Miller WC; HPTN 074 Study Team.

J Int AIDS Soc. 2018 Oct;21(10):e25195. doi: 10.1002/jia2.25195.


After surgery for stage II or III colorectal cancer, more vs less frequent follow-up did not differ for 5-year mortality.

Clarke WT, Feuerstein JD.

Ann Intern Med. 2018 Oct 16;169(8):JC38. doi: 10.7326/ACPJC-2018-169-8-038. No abstract available.


Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity.

Berg KA, Clarke WP.

Int J Neuropsychopharmacol. 2018 Oct 1;21(10):962-977. doi: 10.1093/ijnp/pyy071. Review.


Accuracy of Self-Reported HIV Status Among African Men and Transgender Women Who Have Sex with Men Who were Screened for Participation in a Research Study: HPTN 075.

Fogel JM, Sandfort T, Zhang Y, Guo X, Clarke W, Breaud A, Cummings V, Hamilton EL, Ogendo A, Kayange N, Panchia R, Dominguez K, Chen YQ, Eshleman SH.

AIDS Behav. 2019 Jan;23(1):289-294. doi: 10.1007/s10461-018-2231-1.


Antiretroviral Drug Use and HIV Drug Resistance Among Young Women in Rural South Africa: HPTN 068.

Zhang Y, Sivay MV, Hudelson SE, Clarke W, Breaud A, Wang J, Piwowar-Manning E, Agyei Y, Fogel JM, Hamilton EL, Selin A, MacPhail C, Kahn K, Gómez-Olivé FX, Hughes JP, Pettifor A, Eshleman SH.

J Acquir Immune Defic Syndr. 2018 Nov 1;79(3):315-322. doi: 10.1097/QAI.0000000000001793.


Fentanyl Delays the Platelet Inhibition Effects of Oral Ticagrelor: Full Report of the PACIFY Randomized Clinical Trial.

Ibrahim K, Shah R, Goli RR, Kickler TS, Clarke WA, Hasan RK, Blumenthal RS, Thiemann DR, Resar JR, Schulman SP, McEvoy JW.

Thromb Haemost. 2018 Aug;118(8):1409-1418. doi: 10.1055/s-0038-1666862. Epub 2018 Jul 4.


Detecting de Novo Homoeologous Recombination Events in Cultivated Brassica napus Using a Genome-Wide SNP Array.

Higgins EE, Clarke WE, Howell EC, Armstrong SJ, Parkin IAP.

G3 (Bethesda). 2018 Jul 31;8(8):2673-2683. doi: 10.1534/g3.118.200118.


Deterministic mechanisms define the long-term anaerobic digestion microbiome and its functionality regardless of the initial microbial community.

Peces M, Astals S, Jensen PD, Clarke WP.

Water Res. 2018 Sep 15;141:366-376. doi: 10.1016/j.watres.2018.05.028. Epub 2018 May 17.


Methodology to determine the extent of anaerobic digestion, composting and CH4 oxidation in a landfill environment.

Obersky L, Rafiee R, Cabral AR, Golding SD, Clarke WP.

Waste Manag. 2018 Jun;76:364-373. doi: 10.1016/j.wasman.2018.02.029. Epub 2018 Mar 7.


Antiretroviral drug use and HIV drug resistance among MSM and transgender women in sub-Saharan Africa.

Zhang Y, Fogel JM, Guo X, Clarke W, Breaud A, Cummings V, Hamilton EL, Ogendo A, Kayange N, Panchia R, Dominguez K, Chen YQ, Sandfort T, Eshleman SH.

AIDS. 2018 Jun 19;32(10):1301-1306. doi: 10.1097/QAD.0000000000001839.


Updates in colorectal cancer screening in inflammatory bowel disease.

Clarke WT, Feuerstein JD.

Curr Opin Gastroenterol. 2018 Jul;34(4):208-216. doi: 10.1097/MOG.0000000000000448. Review.


Undisclosed antiretroviral drug use in Botswana: implication for national estimates.

Moyo S, Gaseitsiwe S, Powis KM, Pretorius Holme M, Mohammed T, Zahralban-Steele M, Yankinde EK, Maphorisa C, Abrams W, Lebelonyane R, Manyake K, Sekoto T, Mmalane M, Gaolathe T, Wirth KE, Makhema J, Lockman S, Clarke W, Essex M, Novitsky V.

AIDS. 2018 Jul 17;32(11):1543-1546. doi: 10.1097/QAD.0000000000001862.


Patients with core antibody positive and surface antigen negative Hepatitis B (anti-HBc+, HBsAg-) on anti-TNF therapy have a low rate of reactivation.

Clarke WT, Amin SS, Papamichael K, Feuerstein JD, Cheifetz AS.

Clin Immunol. 2018 Jun;191:59-62. doi: 10.1016/j.clim.2018.03.013. Epub 2018 Mar 28.


taxMaps: comprehensive and highly accurate taxonomic classification of short-read data in reasonable time.

Corvelo A, Clarke WE, Robine N, Zody MC.

Genome Res. 2018 May;28(5):751-758. doi: 10.1101/gr.225276.117. Epub 2018 Mar 27.


Allosterism within δ Opioid-κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy.

Jacobs BA, Pando MM, Jennings E, Chavera TA, Clarke WP, Berg KA.

Mol Pharmacol. 2018 Apr;93(4):376-386. doi: 10.1124/mol.117.109975. Epub 2018 Feb 7.


Debates in Pain Management Testing.

Melanson SEF, Clarke WA, Fragoza K, Gilligan C, Holdren R, Jannetto PJ, Magnani B, Moore C.

Clin Chem. 2018 May;64(5):769-776. doi: 10.1373/clinchem.2017.275693. Epub 2018 Jan 17. No abstract available.


The validity of self-reported antiretroviral use in persons living with HIV: a population-based study.

Grabowski MK, Reynolds SJ, Kagaayi J, Gray RH, Clarke W, Chang LW, Nakigozi G, Laeyndecker O, Redd AD, Billioux V, Ssekubugu R, Nalugoda F, Wawer MJ, Serwadda D, Quinn TC, Tobian AAR.

AIDS. 2018 Jan 28;32(3):363-369. doi: 10.1097/QAD.0000000000001706.


Pilot scale evaluation of a model to distinguish the rates of simultaneous anaerobic digestion, composting and methane oxidation in static waste beds.

Rafiee R, Obersky L, Xie S, Clarke WP.

Waste Manag. 2018 Jan;71:156-163. doi: 10.1016/j.wasman.2017.11.003. Epub 2017 Nov 7.


Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy.

LoCoco PM, Risinger AL, Smith HR, Chavera TS, Berg KA, Clarke WP.

Elife. 2017 Nov 10;6. pii: e29626. doi: 10.7554/eLife.29626.


The uptake of anaerobic digestion for the organic fraction of municipal solid waste - Push versus pull factors.

Clarke WP.

Bioresour Technol. 2018 Feb;249:1040-1043. doi: 10.1016/j.biortech.2017.10.086. Epub 2017 Oct 26. Review.


Using a whole-body 31P birdcage transmit coil and 16-element receive array for human cardiac metabolic imaging at 7T.

Valkovič L, Dragonu I, Almujayyaz S, Batzakis A, Young LAJ, Purvis LAB, Clarke WT, Wichmann T, Lanz T, Neubauer S, Robson MD, Klomp DWJ, Rodgers CT.

PLoS One. 2017 Oct 26;12(10):e0187153. doi: 10.1371/journal.pone.0187153. eCollection 2017.


Effect of Intravenous Fentanyl on Ticagrelor Absorption and Platelet Inhibition Among Patients Undergoing Percutaneous Coronary Intervention: The PACIFY Randomized Clinical Trial (Platelet Aggregation With Ticagrelor Inhibition and Fentanyl).

McEvoy JW, Ibrahim K, Kickler TS, Clarke WA, Hasan RK, Czarny MJ, Keramati AR, Goli RR, Gratton TP, Brinker JA, Chacko M, Hwang CW, Johnston PV, Miller JM, Trost JC, Herzog WR, Blumenthal RS, Thiemann DR, Resar JR, Schulman SP.

Circulation. 2018 Jan 16;137(3):307-309. doi: 10.1161/CIRCULATIONAHA.117.031678. Epub 2017 Oct 18. No abstract available.


Does Regulatory Really Intersect Reality in Glucose Measurement in the ICU? Is the Issue Testing Method Accuracy or Specimen Type?

DuBois JA, Slingerland RJ, Fokkert M, Roman A, Tran NK, Clarke W, Sartori DA, Palmieri TL, Malic A, Lyon ME, Lyon AW.

Crit Care Med. 2017 Nov;45(11):e1186-e1188. doi: 10.1097/CCM.0000000000002596. No abstract available.


OXSA: An open-source magnetic resonance spectroscopy analysis toolbox in MATLAB.

Purvis LAB, Clarke WT, Biasiolli L, Valkovič L, Robson MD, Rodgers CT.

PLoS One. 2017 Sep 22;12(9):e0185356. doi: 10.1371/journal.pone.0185356. eCollection 2017.


Studies of drug interactions with alpha1-acid glycoprotein by using on-line immunoextraction and high-performance affinity chromatography.

Bi C, Matsuda R, Zhang C, Isingizwe Z, Clarke W, Hage DS.

J Chromatogr A. 2017 Oct 13;1519:64-73. doi: 10.1016/j.chroma.2017.08.073. Epub 2017 Aug 31.


Glycoform analysis of alpha1-acid glycoprotein based on capillary electrophoresis and electrophoretic injection.

Zhang C, Bi C, Clarke W, Hage DS.

J Chromatogr A. 2017 Nov 10;1523:114-122. doi: 10.1016/j.chroma.2017.08.032. Epub 2017 Aug 15.


Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428.

Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AMJ.

Diabetes. 2017 Sep;66(9):2531. doi: 10.2337/db17-er09a. Epub 2017 Jun 29. No abstract available.


Evaluation of a Multidrug Assay for Monitoring Adherence to a Regimen for HIV Preexposure Prophylaxis in a Clinical Study, HIV Prevention Trials Network 073.

Zhang Y, Clarke W, Marzinke MA, Piwowar-Manning E, Beauchamp G, Breaud A, Hendrix CW, Cloherty GA, Emel L, Rose S, Hightow-Weidman L, Siegel M, Shoptaw S, Fields SD, Wheeler D, Eshleman SH.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02743-16. doi: 10.1128/AAC.02743-16. Print 2017 Jul.


Predicting and Reducing Driving Mishaps Among Drivers With Type 1 Diabetes.

Cox DJ, Gonder-Frederick LA, Singh H, Ingersoll KS, Banton T, Grabman JH, Schmidt K, Clarke W.

Diabetes Care. 2017 Jun;40(6):742-750. doi: 10.2337/dc16-0995. Epub 2017 Apr 12.


BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.

King D, Iwuagwu C, Cook J, McDonald IM, Mate R, Zusi FC, Hill MD, Fang H, Zhao R, Wang B, Easton AE, Miller R, Post-Munson D, Knox RJ, Gallagher L, Westphal R, Molski T, Fan J, Clarke W, Benitex Y, Lentz KA, Denton R, Morgan D, Zaczek R, Lodge NJ, Bristow LJ, Macor JE, Olson RE.

ACS Med Chem Lett. 2017 Feb 8;8(3):366-371. doi: 10.1021/acsmedchemlett.7b00032. eCollection 2017 Mar 9.


Phosphodiester content measured in human liver by in vivo 31 P MR spectroscopy at 7 tesla.

Purvis LAB, Clarke WT, Valkovič L, Levick C, Pavlides M, Barnes E, Cobbold JF, Robson MD, Rodgers CT.

Magn Reson Med. 2017 Dec;78(6):2095-2105. doi: 10.1002/mrm.26635. Epub 2017 Feb 28.


Bedside Glucose Monitoring-Is it Safe? A New, Regulatory-Compliant Risk Assessment Evaluation Protocol in Critically Ill Patient Care Settings.

DuBois JA, Slingerland RJ, Fokkert M, Roman A, Tran NK, Clarke W, Sartori DA, Palmieri TL, Malic A, Lyon ME, Lyon AW.

Crit Care Med. 2017 Apr;45(4):567-574. doi: 10.1097/CCM.0000000000002252.


Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.

Hill MD, Fang H, King HD, Iwuagwu CI, McDonald IM, Cook J, Zusi FC, Mate RA, Knox RJ, Post-Munson D, Easton A, Miller R, Lentz K, Clarke W, Benitex Y, Lodge N, Zaczek R, Denton R, Morgan D, Bristow L, Macor JE, Olson R.

ACS Med Chem Lett. 2016 Dec 1;8(1):133-137. doi: 10.1021/acsmedchemlett.6b00471. eCollection 2017 Jan 12.


A mass balance model to estimate the rate of composting, methane oxidation and anaerobic digestion in soil covers and shallow waste layers.

Rafiee R, Obersky L, Xie S, Clarke WP.

Waste Manag. 2017 May;63:196-202. doi: 10.1016/j.wasman.2016.12.025. Epub 2017 Jan 12.


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