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Inability of Current Dosing to Achieve Carboplatin Therapeutic Targets in People with Advanced Non-Small Cell Lung Cancer: Impact of Systemic Inflammation on Carboplatin Exposure and Clinical Outcomes.

Harris BDW, Phan V, Perera V, Szyc A, Galettis P, Martin JH, Walpole E, McLachlan AJ, Clarke SJ, Reuter SE, Charles KA.

Clin Pharmacokinet. 2020 Feb 7. doi: 10.1007/s40262-020-00870-6. [Epub ahead of print]


Evaluation of Fluorodeoxyglucose Positron Emission Tomography Scanning in the Neoadjuvant Therapy Paradigm in Pancreatic Ductal Adenocarcinoma.

Itchins M, Chua TC, Arena J, Jamieson NB, Nahm CB, OʼConnell RL, Bailey EA, Schembri GP, Gill AJ, Kneebone A, Hruby G, Mittal A, Pavlakis N, Clarke SJ, Samra JS.

Pancreas. 2020 Feb;49(2):224-229. doi: 10.1097/MPA.0000000000001472.


Sub-acute Toxicity in Non-cancerous Tissue and Immune-Related Adverse Events of a Novel Combination Therapy for Cancer.

McKelvey KJ, Hudson AL, Prasanna Kumar R, Eade T, Clarke SJ, Wheeler HR, Diakos CI, Howell VM.

Front Oncol. 2020 Jan 14;9:1504. doi: 10.3389/fonc.2019.01504. eCollection 2019.


Serum bicarbonate is a marker of peri-operative mortality but is not associated with long term survival in colorectal cancer.

Chan JCY, Diakos CI, Engel A, Chan DLH, Pavlakis N, Gill A, Clarke SJ.

PLoS One. 2020 Jan 30;15(1):e0228466. doi: 10.1371/journal.pone.0228466. eCollection 2020.


Single phase charge ordered stoichiometric CaFe3O5 with commensurate and incommensurate trimeron ordering.

Cassidy SJ, Orlandi F, Manuel P, Clarke SJ.

Nat Commun. 2019 Dec 2;10(1):5475. doi: 10.1038/s41467-019-13450-5.


Mass Cytometry Reveals a Sustained Reduction in CD16+ Natural Killer Cells Following Chemotherapy in Colorectal Cancer Patients.

Shinko D, McGuire HM, Diakos CI, Pavlakis N, Clarke SJ, Byrne SN, Charles KA.

Front Immunol. 2019 Nov 5;10:2584. doi: 10.3389/fimmu.2019.02584. eCollection 2019.


High metabolic tumour volume on FDG PET predicts poor survival from neuroendocrine neoplasms.

Chan DL, Bernard E, Schembri G, Roach P, Johnson M, Pavlakis N, Clarke SJ, Bailey D.

Neuroendocrinology. 2019 Nov 12. doi: 10.1159/000504673. [Epub ahead of print]


In-situ Electrochemical X-ray Diffraction: A Rigorous Method to Navigate within Phase Diagrams Reveals β-Fe1+x Se as Superconductor for All x.

Rasche B, Yang M, Nikonow L, Cooper JFK, Murray CA, Day SJ, Kleiner K, Clarke SJ, Compton RG.

Angew Chem Int Ed Engl. 2019 Oct 21;58(43):15401-15406. doi: 10.1002/anie.201907426. Epub 2019 Sep 4.


Expression Patterns of Genes Encoding Sugar and Potassium Transport Proteins Are Simultaneously Upregulated or Downregulated When Carbon and Potassium Availability Is Modified in Shiraz (Vitis vinifera L.) Berries.

Coetzee ZA, Walker RR, Liao S, Barril C, Deloire AJ, Clarke SJ, Tyerman SD, Rogiers SY.

Plant Cell Physiol. 2019 Oct 1;60(10):2331-2342. doi: 10.1093/pcp/pcz130.


Tumor sidedness is not an independent prognostic marker of colorectal cancer patients undergoing curative resection: A retrospective cohort study.

Chan JCY, Diakos CI, Engel A, Chan DLH, Pavlakis N, Gill A, Clarke SJ.

PLoS One. 2019 Jun 12;14(6):e0218207. doi: 10.1371/journal.pone.0218207. eCollection 2019.


Synthesis, Structure, and Compositional Tuning of the Layered Oxide Tellurides Sr2MnO2Cu2- xTe2 and Sr2CoO2Cu2Te2.

Blandy JN, Parker DR, Cassidy SJ, Woodruff DN, Xu X, Clarke SJ.

Inorg Chem. 2019 Jun 17;58(12):8140-8150. doi: 10.1021/acs.inorgchem.9b00919. Epub 2019 Jun 5.


ELDOR-detected NMR beyond hyperfine couplings: a case study with Cu(ii)-porphyrin dimers.

Wili N, Richert S, Limburg B, Clarke SJ, Anderson HL, Timmel CR, Jeschke G.

Phys Chem Chem Phys. 2019 Jun 5;21(22):11676-11688. doi: 10.1039/c9cp01760g.


Straddling medical specialties: should we have more comprehensive advanced training?

Learoyd DL, Clarke SJ.

Intern Med J. 2019 May;49(5):669-671. doi: 10.1111/imj.14278.


Glucagon-Like Peptide-1-Mediated Cardioprotection Does Not Reduce Right Ventricular Stunning and Cumulative Ischemic Dysfunction After Coronary Balloon Occlusion.

Giblett JP, Axell RG, White PA, Aetesam-Ur-Rahman M, Clarke SJ, Figg N, Bennett MR, West NEJ, Hoole SP.

JACC Basic Transl Sci. 2019 Apr 29;4(2):222-233. doi: 10.1016/j.jacbts.2018.12.002. eCollection 2019 Apr.


Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and Cancer.

Currey N, Jahan Z, Caldon CE, Tran PN, Benthani F, De Lacavalerie P, Roden DL, Gloss BS, Campos C, Bean EG, Bullman A, Reibe-Pal S, Dinger ME, Febbraio MA, Clarke SJ, Dahlstrom JE, Kohonen-Corish MRJ.

Cell Mol Gastroenterol Hepatol. 2019;7(4):819-839. doi: 10.1016/j.jcmgh.2019.01.009. Epub 2019 Mar 2.


Layered CeSO and LiCeSO Oxide Chalcogenides Obtained via Topotactic Oxidative and Reductive Transformations.

Cassidy SJ, Pitcher MJ, Lim JJK, Hadermann J, Allen JP, Watson GW, Britto S, Chong EJ, Free DG, Grey CP, Clarke SJ.

Inorg Chem. 2019 Mar 18;58(6):3838-3850. doi: 10.1021/acs.inorgchem.8b03485. Epub 2019 Feb 25.


Afatinib in patients with metastatic or recurrent HER2-mutant lung cancers: a retrospective international multicentre study.

Lai WV, Lebas L, Barnes TA, Milia J, Ni A, Gautschi O, Peters S, Ferrara R, Plodkowski AJ, Kavanagh J, Sabari JK, Clarke SJ, Pavlakis N, Drilon A, Rudin CM, Arcila ME, Leighl NB, Shepherd FA, Kris MG, Mazières J, Li BT.

Eur J Cancer. 2019 Mar;109:28-35. doi: 10.1016/j.ejca.2018.11.030. Epub 2019 Jan 24.


Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study.

Clarke SJ, Pettit S, Giblett JP, Zhao T, Kydd AC, Albrechtsen NJW, Deacon CF, Parameshwar J, Hoole SP.

Clin Ther. 2019 Jan;41(1):118-127.e0. doi: 10.1016/j.clinthera.2018.11.013. Epub 2018 Dec 28.


GLP-1 Is a Coronary Artery Vasodilator in Humans.

Clarke SJ, Giblett JP, Yang LL, Hubsch A, Zhao T, Aetesam-Ur-Rahman M, West NEJ, O'Sullivan M, Figg N, Bennett M, Wewer Albrechtsen NJ, Deacon CF, Cheriyan J, Hoole SP.

J Am Heart Assoc. 2018 Nov 20;7(22):e010321. doi: 10.1161/JAHA.118.010321.


A Horizon Scan of Emerging Issues for Global Conservation in 2019.

Sutherland WJ, Broad S, Butchart SHM, Clarke SJ, Collins AM, Dicks LV, Doran H, Esmail N, Fleishman E, Frost N, Gaston KJ, Gibbons DW, Hughes AC, Jiang Z, Kelman R, LeAnstey B, le Roux X, Lickorish FA, Monk KA, Mortimer D, Pearce-Higgins JW, Peck LS, Pettorelli N, Pretty J, Seymour CL, Spalding MD, Wentworth J, Ockendon N.

Trends Ecol Evol. 2019 Jan;34(1):83-94. doi: 10.1016/j.tree.2018.11.001. Epub 2018 Dec 13. Review.


The role of fruit exposure in the late season decline of grape berry mesocarp cell vitality.

Clarke SJ, Rogiers SY.

Plant Physiol Biochem. 2019 Feb;135:69-76. doi: 10.1016/j.plaphy.2018.11.025. Epub 2018 Nov 27.


Synthesis, Structure, and Properties of the Layered Oxide Chalcogenides Sr2CuO2Cu2S2 and Sr2CuO2Cu2Se2.

Blandy JN, Liu S, Smura CF, Cassidy SJ, Woodruff DN, McGrady JE, Clarke SJ.

Inorg Chem. 2018 Dec 17;57(24):15379-15388. doi: 10.1021/acs.inorgchem.8b02698. Epub 2018 Nov 27.


The integration of pharmacology and pathophysiology into locoregional chemotherapy delivery via mass fluid transfer.

Lane RJ, Khin NY, Rogan CM, Magnussen JS, Ho-Shon K, Pavlakis N, Clarke SJ, Hugh TJ.

J Control Release. 2018 Dec 28;292:18-28. doi: 10.1016/j.jconrel.2018.10.019. Epub 2018 Oct 19. Review.


Complex Magnetic Ordering in the Oxide Selenide Sr2Fe3Se2O3.

Cassidy SJ, Orlandi F, Manuel P, Hadermann J, Scrimshire A, Bingham PA, Clarke SJ.

Inorg Chem. 2018 Aug 20;57(16):10312-10322. doi: 10.1021/acs.inorgchem.8b01542. Epub 2018 Jul 31.


Pattern of care and survival of anaplastic lymphoma kinase rearranged non-small cell lung cancer (ALK+ NSCLC) in an Australian Metropolitan Tertiary Referral Centre: A retrospective cohort analysis.

Itchins M, Hayes SA, Gill AJ, Cooper W, O'Connell R, Howell VM, Clarke SJ, Pavlakis N.

Asia Pac J Clin Oncol. 2018 Oct;14(5):e275-e282. doi: 10.1111/ajco.12877. Epub 2018 Apr 19.


Prognostic indices of inflammatory markers, cognitive function and fatigue for survival in patients with localised colorectal cancer.

Vardy JL, Dhillon HM, Pond GR, Renton C, Clarke SJ, Tannock IF.

ESMO Open. 2018 Feb 14;3(2):e000302. doi: 10.1136/esmoopen-2017-000302. eCollection 2018.


Challenges in chemotherapy delivery: comparison of standard chemotherapy delivery to locoregional vascular mass fluid transfer.

Lane RJ, Khin NY, Pavlakis N, Hugh TJ, Clarke SJ, Magnussen J, Rogan C, Flekser RL.

Future Oncol. 2018 Mar;14(7):647-663. doi: 10.2217/fon-2017-0546. Epub 2018 Mar 7.


Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer.

Chou A, Froio D, Nagrial AM, Parkin A, Murphy KJ, Chin VT, Wohl D, Steinmann A, Stark R, Drury A, Walters SN, Vennin C, Burgess A, Pinese M, Chantrill LA, Cowley MJ, Molloy TJ; Australian Pancreatic Cancer Genome Initiative (APGI), Waddell N, Johns A, Grimmond SM, Chang DK, Biankin AV, Sansom OJ, Morton JP, Grey ST, Cox TR, Turchini J, Samra J, Clarke SJ, Timpson P, Gill AJ, Pajic M.

Gut. 2018 Dec;67(12):2142-2155. doi: 10.1136/gutjnl-2017-315144. Epub 2017 Oct 28.


Impact of reduced atmospheric CO2 and varied potassium supply on carbohydrate and potassium distribution in grapevine and grape berries (Vitis vinifera L.).

Coetzee ZA, Walker RR, Deloire AJ, Barril C, Clarke SJ, Rogiers SY.

Plant Physiol Biochem. 2017 Nov;120:252-260. doi: 10.1016/j.plaphy.2017.10.008. Epub 2017 Oct 13.


Changing Therapeutic Paradigms: Predicting mCRC Lesion Response to Selective Internal Radionuclide Therapy (SIRT) based on Critical Absorbed Dose Thresholds: A Case Study.

Willowson KP, Bernard EJ, Maher R, Clarke SJ, Bailey DL.

Asia Ocean J Nucl Med Biol. 2017 Winter;5(1):66-69. doi: 10.22038/aojnmb.2016.7892.


Treatment of ALK-rearranged non-small cell lung cancer: A review of the landscape and approach to emerging patterns of treatment resistance in the Australian context.

Itchins M, Chia PL, Hayes SA, Howell VM, Gill AJ, Cooper WA, John T, Mitchell P, Millward M, Clarke SJ, Solomon B, Pavlakis N.

Asia Pac J Clin Oncol. 2017 Aug;13 Suppl 3:3-13. doi: 10.1111/ajco.12754. Review.


Cancer-Related Systemic Inflammation: The Challenges and Therapeutic Opportunities for Personalized Medicine.

Shinko D, Diakos CI, Clarke SJ, Charles KA.

Clin Pharmacol Ther. 2017 Oct;102(4):599-610. doi: 10.1002/cpt.789. Epub 2017 Aug 24. Review.


Clinical and imaging-based prognostic factors in radioembolisation of liver metastases from colorectal cancer: a retrospective exploratory analysis.

Willowson KP, Hayes AR, Chan DLH, Tapner M, Bernard EJ, Maher R, Pavlakis N, Clarke SJ, Bailey DL.

EJNMMI Res. 2017 Dec;7(1):46. doi: 10.1186/s13550-017-0292-1. Epub 2017 May 23.


Impact of physical activity on fatigue and quality of life in people with advanced lung cancer: a randomized controlled trial.

Dhillon HM, Bell ML, van der Ploeg HP, Turner JD, Kabourakis M, Spencer L, Lewis C, Hui R, Blinman P, Clarke SJ, Boyer MJ, Vardy JL.

Ann Oncol. 2017 Aug 1;28(8):1889-1897. doi: 10.1093/annonc/mdx205.


Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: Proposal for a Novel Grading Scheme with Prognostic Significance.

Chan DL, Pavlakis N, Schembri GP, Bernard EJ, Hsiao E, Hayes A, Barnes T, Diakos C, Khasraw M, Samra J, Eslick E, Roach PJ, Engel A, Clarke SJ, Bailey DL.

Theranostics. 2017 Mar 1;7(5):1149-1158. doi: 10.7150/thno.18068. eCollection 2017.


Prognostic and predictive biomarkers in neuroendocrine tumours.

Chan DL, Clarke SJ, Diakos CI, Roach PJ, Bailey DL, Singh S, Pavlakis N.

Crit Rev Oncol Hematol. 2017 May;113:268-282. doi: 10.1016/j.critrevonc.2017.03.017. Epub 2017 Mar 18. Review.


A Longitudinal Investigation of Inflammatory Markers in Colorectal Cancer Patients Perioperatively Demonstrates Benefit in Serial Remeasurement.

Chan JCY, Diakos CI, Chan DLH, Engel A, Pavlakis N, Gill A, Clarke SJ.

Ann Surg. 2018 Jun;267(6):1119-1125. doi: 10.1097/SLA.0000000000002251.


BACCN Conference 2016: A Regional Advisor Perspective.

Clarke SJ.

Nurs Crit Care. 2017 Jan;22(1):58-59. doi: 10.1111/nicc.2_12274. No abstract available.


The addition of anti-angiogenic tyrosine kinase inhibitors to chemotherapy for patients with advanced non-small-cell lung cancers: A meta-analysis of randomized trials.

Li BT, Barnes TA, Chan DL, Naidoo J, Lee A, Khasraw M, Marx GM, Kris MG, Clarke SJ, Drilon A, Rudin CM, Pavlakis N.

Lung Cancer. 2016 Dec;102:21-27. doi: 10.1016/j.lungcan.2016.10.004. Epub 2016 Oct 17.


Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial.

Sclafani F, Kim TY, Cunningham D, Kim TW, Tabernero J, Schmoll HJ, Roh JK, Kim SY, Park YS, Guren TK, Hawkes E, Clarke SJ, Ferry D, Frodin JE, Ayers M, Nebozhyn M, Peckitt C, Loboda A, Watkins DJ.

Int J Cancer. 2017 Jan 15;140(2):431-439. doi: 10.1002/ijc.30453. Epub 2016 Oct 17.


Complex Microstructure and Magnetism in Polymorphic CaFeSeO.

Cassidy SJ, Batuk M, Batuk D, Hadermann J, Woodruff DN, Thompson AL, Clarke SJ.

Inorg Chem. 2016 Oct 17;55(20):10714-10726. doi: 10.1021/acs.inorgchem.6b01951. Epub 2016 Oct 5.


The Parent Li(OH)FeSe Phase of Lithium Iron Hydroxide Selenide Superconductors.

Woodruff DN, Schild F, Topping CV, Cassidy SJ, Blandy JN, Blundell SJ, Thompson AL, Clarke SJ.

Inorg Chem. 2016 Oct 3;55(19):9886-9891. Epub 2016 Sep 22.


Fatigue in people with localized colorectal cancer who do and do not receive chemotherapy: a longitudinal prospective study.

Vardy JL, Dhillon HM, Pond GR, Renton C, Dodd A, Zhang H, Clarke SJ, Tannock IF.

Ann Oncol. 2016 Sep;27(9):1761-7. doi: 10.1093/annonc/mdw252. Epub 2016 Jul 20.


Glucagon-like peptide-1 derived cardioprotection does not utilize a KATP-channel dependent pathway: mechanistic insights from human supply and demand ischemia studies.

Giblett JP, Axell RG, White PA, Clarke SJ, McCormick L, Read PA, Reinhold J, Brown AJ, O'Sullivan M, West NE, Dutka DP, Hoole SP.

Cardiovasc Diabetol. 2016 Jul 19;15:99. doi: 10.1186/s12933-016-0416-3.


Exhaled breath condensate for lung cancer protein analysis: a review of methods and biomarkers.

Hayes SA, Haefliger S, Harris B, Pavlakis N, Clarke SJ, Molloy MP, Howell VM.

J Breath Res. 2016 Jul 5;10(3):034001. doi: 10.1088/1752-7155/10/3/034001. Review.


PET monitoring of liver directed selective internal radionuclide therapy for metastatic gastro-oesophageal cancer.

Bailey DL, Lee A, Li BT, Clarke SJ.

BMJ Case Rep. 2016 Jun 30;2016. pii: bcr2016215645. doi: 10.1136/bcr-2016-215645. No abstract available.


Systematic Review and Meta-Analysis on the Role of Chemotherapy in Advanced and Metastatic Neuroendocrine Tumor (NET).

Wong MH, Chan DL, Lee A, Li BT, Lumba S, Clarke SJ, Samra J, Pavlakis N.

PLoS One. 2016 Jun 30;11(6):e0158140. doi: 10.1371/journal.pone.0158140. eCollection 2016. Review.


Glucagon-Like Peptide-1: A Promising Agent for Cardioprotection During Myocardial Ischemia.

Giblett JP, Clarke SJ, Dutka DP, Hoole SP.

JACC Basic Transl Sci. 2016 Jun 27;1(4):267-276. doi: 10.1016/j.jacbts.2016.03.011. eCollection 2016 Jun. Review.


Analytical performance of nano-LC-SRM using nondepleted human plasma over an 18-month period.

Song X, Amirkhani A, Wu JX, Pascovici D, Zaw T, Xavier D, Clarke SJ, Molloy MP.

Proteomics. 2016 Aug;16(15-16):2118-27. doi: 10.1002/pmic.201500507. Epub 2016 Jul 25.


Systematic Review of the Role of Targeted Therapy in Metastatic Neuroendocrine Tumors.

Lee A, Chan DL, Wong MH, Li BT, Lumba S, Clarke SJ, Samra J, Pavlakis N.

Neuroendocrinology. 2017;104(3):209-222. doi: 10.1159/000446115. Epub 2016 Apr 16. Review.

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