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General and specific interactions of the phospholipid bilayer with P-type ATPases.

Hossain KR, Clarke RJ.

Biophys Rev. 2019 Jun;11(3):353-364. doi: 10.1007/s12551-019-00533-2. Epub 2019 May 9. Review.


The bony labyrinth of StW 573 ("Little Foot"): Implications for early hominin evolution and paleobiology.

Beaudet A, Clarke RJ, Bruxelles L, Carlson KJ, Crompton R, de Beer F, Dhaene J, Heaton JL, Jakata K, Jashashvili T, Kuman K, McClymont J, Pickering TR, Stratford D.

J Hum Evol. 2019 Feb;127:67-80. doi: 10.1016/j.jhevol.2018.12.002. Epub 2018 Dec 22.


Excavation, reconstruction and taphonomy of the StW 573 Australopithecus prometheus skeleton from Sterkfontein Caves, South Africa.

Clarke RJ.

J Hum Evol. 2019 Feb;127:41-53. doi: 10.1016/j.jhevol.2018.11.010. Epub 2018 Dec 20. No abstract available.


Cholesterol depletion inhibits Na+,K+-ATPase activity in a near-native membrane environment.

Garcia A, Lev B, Hossain KR, Gorman A, Diaz D, Pham THN, Cornelius F, Allen TW, Clarke RJ.

J Biol Chem. 2019 Apr 12;294(15):5956-5969. doi: 10.1074/jbc.RA118.006223. Epub 2019 Feb 15.


Dynamics of the Electromagnetic Fields Induced by Fast Electron Propagation in Near-Solid-Density Media.

Romagnani L, Robinson APL, Clarke RJ, Doria D, Lancia L, Nazarov W, Notley MM, Pipahl A, Quinn K, Ramakrishna B, Wilson PA, Fuchs J, Willi O, Borghesi M.

Phys Rev Lett. 2019 Jan 18;122(2):025001. doi: 10.1103/PhysRevLett.122.025001.


Effect of Cholesterol on the Dipole Potential of Lipid Membranes.

Clarke RJ.

Adv Exp Med Biol. 2019;1115:135-154. doi: 10.1007/978-3-030-04278-3_6.


The endocast of StW 573 ("Little Foot") and hominin brain evolution.

Beaudet A, Clarke RJ, de Jager EJ, Bruxelles L, Carlson KJ, Crompton R, de Beer F, Dhaene J, Heaton JL, Jakata K, Jashashvili T, Kuman K, McClymont J, Pickering TR, Stratford D.

J Hum Evol. 2019 Jan;126:112-123. doi: 10.1016/j.jhevol.2018.11.009. Epub 2018 Dec 15.


Hominin vertebrae and upper limb bone fossils from Sterkfontein Caves, South Africa (1998-2003 excavations).

Pickering TR, Heaton JL, Clarke RJ, Stratford D.

Am J Phys Anthropol. 2019 Mar;168(3):459-480. doi: 10.1002/ajpa.23758. Epub 2018 Dec 23.


Novel methods for segment-specific blood flow simulation for the liver.

Barléon N, Clarke RJ, Ho H.

Comput Methods Biomech Biomed Engin. 2018 Nov;21(15):780-783. doi: 10.1080/10255842.2018.1520224. Epub 2018 Nov 6.


Influences of transversely isotropic rheology and translational diffusion on the stability of active suspensions.

Holloway CR, Cupples G, Smith DJ, Green JEF, Clarke RJ, Dyson RJ.

R Soc Open Sci. 2018 Aug 15;5(8):180456. doi: 10.1098/rsos.180456. eCollection 2018 Aug.


Novel scintillator-based x-ray spectrometer for use on high repetition laser plasma interaction experiments.

Rusby DR, Armstrong CD, Brenner CM, Clarke RJ, McKenna P, Neely D.

Rev Sci Instrum. 2018 Jul;89(7):073502. doi: 10.1063/1.5019213.


Evolutionary Analysis of the Lysine-Rich N-terminal Cytoplasmic Domains of the Gastric H+,K+-ATPase and the Na+,K+-ATPase.

Diaz D, Clarke RJ.

J Membr Biol. 2018 Dec;251(5-6):653-666. doi: 10.1007/s00232-018-0043-x. Epub 2018 Jul 28.


Questioning the Associations of ω-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks-Reply.

Clarke RJ, Aung T, Armitage J.

JAMA Cardiol. 2018 Aug 1;3(8):781-782. doi: 10.1001/jamacardio.2018.1312. No abstract available.


Dual Ion Species Plasma Expansion from Isotopically Layered Cryogenic Targets.

Scott GG, Carroll DC, Astbury S, Clarke RJ, Hernandez-Gomez C, King M, Alejo A, Arteaga IY, Dance RJ, Higginson A, Hook S, Liao G, Liu H, Mirfayzi SR, Rusby DR, Selwood MP, Spindloe C, Tolley MK, Wagner F, Zemaityte E, Borghesi M, Kar S, Li Y, Roth M, McKenna P, Neely D.

Phys Rev Lett. 2018 May 18;120(20):204801. doi: 10.1103/PhysRevLett.120.204801.


Cranial vault thickness variation and inner structural organization in the StW 578 hominin cranium from Jacovec Cavern, South Africa.

Beaudet A, Carlson KJ, Clarke RJ, de Beer F, Dhaene J, Heaton JL, Pickering TR, Stratford D.

J Hum Evol. 2018 Aug;121:204-220. doi: 10.1016/j.jhevol.2018.04.004. Epub 2018 May 21.


How changes in interconnectivity affect the bulk properties of articular cartilage: a fibre network study.

Bilton MA, Thambyah A, Clarke RJ.

Biomech Model Mechanobiol. 2018 Oct;17(5):1297-1315. doi: 10.1007/s10237-018-1027-6. Epub 2018 May 18.


Kinetic contribution to extracellular Na+/K+ selectivity in the Na+/K+ pump.

Vleeskens E, Clarke RJ.

FEBS Open Bio. 2018 Apr 16;8(5):854-859. doi: 10.1002/2211-5463.12418. eCollection 2018 May.


Hominin hand bone fossils from Sterkfontein Caves, South Africa (1998-2003 excavations).

Pickering TR, Heaton JL, Clarke RJ, Stratford D.

J Hum Evol. 2018 May;118:89-102. doi: 10.1016/j.jhevol.2018.02.014. Epub 2018 Mar 22.


Interaction of N-terminal peptide analogues of the Na+,K+-ATPase with membranes.

Nguyen K, Garcia A, Sani MA, Diaz D, Dubey V, Clayton D, Dal Poggetto G, Cornelius F, Payne RJ, Separovic F, Khandelia H, Clarke RJ.

Biochim Biophys Acta Biomembr. 2018 Jun;1860(6):1282-1291. doi: 10.1016/j.bbamem.2018.03.002. Epub 2018 Mar 6.


Near-100 MeV protons via a laser-driven transparency-enhanced hybrid acceleration scheme.

Higginson A, Gray RJ, King M, Dance RJ, Williamson SDR, Butler NMH, Wilson R, Capdessus R, Armstrong C, Green JS, Hawkes SJ, Martin P, Wei WQ, Mirfayzi SR, Yuan XH, Kar S, Borghesi M, Clarke RJ, Neely D, McKenna P.

Nat Commun. 2018 Feb 20;9(1):724. doi: 10.1038/s41467-018-03063-9.


Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke.

Holmes MV, Millwood IY, Kartsonaki C, Hill MR, Bennett DA, Boxall R, Guo Y, Xu X, Bian Z, Hu R, Walters RG, Chen J, Ala-Korpela M, Parish S, Clarke RJ, Peto R, Collins R, Li L, Chen Z; China Kadoorie Biobank Collaborative Group.

J Am Coll Cardiol. 2018 Feb 13;71(6):620-632. doi: 10.1016/j.jacc.2017.12.006.


Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study.

Gan W, Clarke RJ, Mahajan A, Kulohoma B, Kitajima H, Robertson NR, Rayner NW, Walters RG, Holmes MV, Chen Z, McCarthy MI.

Wellcome Open Res. 2017 Aug 22;2:68. doi: 10.12688/wellcomeopenres.12288.1. eCollection 2017.


Electrostatic Stabilization Plays a Central Role in Autoinhibitory Regulation of the Na+,K+-ATPase.

Jiang Q, Garcia A, Han M, Cornelius F, Apell HJ, Khandelia H, Clarke RJ.

Biophys J. 2017 Jan 24;112(2):288-299. doi: 10.1016/j.bpj.2016.12.008.


The voltage-sensitive dye RH421 detects a Na+,K+-ATPase conformational change at the membrane surface.

Garcia A, Pratap PR, Lüpfert C, Cornelius F, Jacquemin D, Lev B, Allen TW, Clarke RJ.

Biochim Biophys Acta Biomembr. 2017 May;1859(5):813-823. doi: 10.1016/j.bbamem.2017.01.022. Epub 2017 Jan 20.


OH-65: The earliest evidence for right-handedness in the fossil record.

Frayer DW, Clarke RJ, Fiore I, Blumenschine RJ, Pérez-Pérez A, Martinez LM, Estebaranz F, Holloway R, Bondioli L.

J Hum Evol. 2016 Nov;100:65-72. doi: 10.1016/j.jhevol.2016.07.002.


New early Pleistocene hominin teeth from the Swartkrans Formation, South Africa.

Pickering TR, Heaton JL, Sutton MB, Clarke RJ, Kuman K, Senjem JH, Brain CK.

J Hum Evol. 2016 Nov;100:1-15. doi: 10.1016/j.jhevol.2016.08.005.


Evaluating laser-driven Bremsstrahlung radiation sources for imaging and analysis of nuclear waste packages.

Jones CP, Brenner CM, Stitt CA, Armstrong C, Rusby DR, Mirfayzi SR, Wilson LA, Alejo A, Ahmed H, Allott R, Butler NMH, Clarke RJ, Haddock D, Hernandez-Gomez C, Higginson A, Murphy C, Notley M, Paraskevoulakos C, Jowsey J, McKenna P, Neely D, Kar S, Scott TB.

J Hazard Mater. 2016 Nov 15;318:694-701. doi: 10.1016/j.jhazmat.2016.07.057. Epub 2016 Jul 26.


Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

Gan W, Walters RG, Holmes MV, Bragg F, Millwood IY, Banasik K, Chen Y, Du H, Iona A, Mahajan A, Yang L, Bian Z, Guo Y, Clarke RJ, Li L, McCarthy MI, Chen Z; China Kadoorie Biobank Collaborative Group.

Diabetologia. 2016 Jul;59(7):1446-1457. doi: 10.1007/s00125-016-3920-9. Epub 2016 Apr 6.


Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion.

Garcia A, Liu CC, Cornelius F, Clarke RJ, Rasmussen HH.

Biophys J. 2016 Mar 8;110(5):1099-109. doi: 10.1016/j.bpj.2016.01.014.


A laser driven pulsed X-ray backscatter technique for enhanced penetrative imaging.

Deas RM, Wilson LA, Rusby D, Alejo A, Allott R, Black PP, Black SE, Borghesi M, Brenner CM, Bryant J, Clarke RJ, Collier JC, Edwards B, Foster P, Greenhalgh J, Hernandez-Gomez C, Kar S, Lockley D, Moss RM, Najmudin Z, Pattathil R, Symes D, Whittle MD, Wood JC, McKenna P, Neely D.

J Xray Sci Technol. 2015;23(6):791-7. doi: 10.3233/XST-150520.


Stimulation of Na(+),K(+)-ATPase Activity as a Possible Driving Force in Cholesterol Evolution.

Lambropoulos N, Garcia A, Clarke RJ.

J Membr Biol. 2016 Jun;249(3):251-9. doi: 10.1007/s00232-015-9864-z. Epub 2015 Dec 29.


Laboratory measurements of resistivity in warm dense plasmas relevant to the microphysics of brown dwarfs.

Booth N, Robinson AP, Hakel P, Clarke RJ, Dance RJ, Doria D, Gizzi LA, Gregori G, Koester P, Labate L, Levato T, Li B, Makita M, Mancini RC, Pasley J, Rajeev PP, Riley D, Wagenaars E, Waugh JN, Woolsey NC.

Nat Commun. 2015 Nov 6;6:8742. doi: 10.1038/ncomms9742.


Dipole-Potential-Mediated Effects on Ion Pump Kinetics.

Clarke RJ.

Biophys J. 2015 Oct 20;109(8):1513-20. doi: 10.1016/j.bpj.2015.08.022. Review.


A boundary-integral representation for biphasic mixture theory, with application to the post-capillary glycocalyx.

Sumets PP, Cater JE, Long DS, Clarke RJ.

Proc Math Phys Eng Sci. 2015 Jul 8;471(2179):20140955.


Membrane accessibility of glutathione.

Garcia A, Eljack ND, Sani MA, Separovic F, Rasmussen HH, Kopec W, Khandelia H, Cornelius F, Clarke RJ.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2430-6. doi: 10.1016/j.bbamem.2015.07.016. Epub 2015 Jul 30.


Genetically determined height and coronary artery disease.

Nelson CP, Hamby SE, Saleheen D, Hopewell JC, Zeng L, Assimes TL, Kanoni S, Willenborg C, Burgess S, Amouyel P, Anand S, Blankenberg S, Boehm BO, Clarke RJ, Collins R, Dedoussis G, Farrall M, Franks PW, Groop L, Hall AS, Hamsten A, Hengstenberg C, Hovingh GK, Ingelsson E, Kathiresan S, Kee F, König IR, Kooner J, Lehtimäki T, März W, McPherson R, Metspalu A, Nieminen MS, O'Donnell CJ, Palmer CN, Peters A, Perola M, Reilly MP, Ripatti S, Roberts R, Salomaa V, Shah SH, Schreiber S, Siegbahn A, Thorsteinsdottir U, Veronesi G, Wareham N, Willer CJ, Zalloua PA, Erdmann J, Deloukas P, Watkins H, Schunkert H, Danesh J, Thompson JR, Samani NJ; CARDIoGRAM+C4D Consortium.

N Engl J Med. 2015 Apr 23;372(17):1608-18. doi: 10.1056/NEJMoa1404881. Epub 2015 Apr 8.


New cosmogenic burial ages for Sterkfontein Member 2 Australopithecus and Member 5 Oldowan.

Granger DE, Gibbon RJ, Kuman K, Clarke RJ, Bruxelles L, Caffee MW.

Nature. 2015 Jun 4;522(7554):85-8. doi: 10.1038/nature14268. Epub 2015 Apr 1.


Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin.

Eljack ND, Ma HY, Drucker J, Shen C, Hambley TW, New EJ, Friedrich T, Clarke RJ.

Metallomics. 2014 Nov;6(11):2126-33. doi: 10.1039/c4mt00238e.


Identification of electric-field-dependent steps in the Na(+),K(+)-pump cycle.

Mares LJ, Garcia A, Rasmussen HH, Cornelius F, Mahmmoud YA, Berlin JR, Lev B, Allen TW, Clarke RJ.

Biophys J. 2014 Sep 16;107(6):1352-63. doi: 10.1016/j.bpj.2014.05.054.


Stratigraphic analysis of the Sterkfontein StW 573 Australopithecus skeleton and implications for its age.

Bruxelles L, Clarke RJ, Maire R, Ortega R, Stratford D.

J Hum Evol. 2014 May;70:36-48. doi: 10.1016/j.jhevol.2014.02.014. Epub 2014 Mar 31.


Extracellular allosteric Na(+) binding to the Na(+),K(+)-ATPase in cardiac myocytes.

Garcia A, Fry NA, Karimi K, Liu CC, Apell HJ, Rasmussen HH, Clarke RJ.

Biophys J. 2013 Dec 17;105(12):2695-705. doi: 10.1016/j.bpj.2013.11.004.


Supramolecular β-cyclodextrin adducts of boron-rich DNA metallointercalators containing dicarba-closo-dodecaborane(12).

Ching HY, Clarke RJ, Rendina LM.

Inorg Chem. 2013 Sep 16;52(18):10356-67. doi: 10.1021/ic401060k. Epub 2013 Aug 28.


NAIS: nuclear activation-based imaging spectroscopy.

Günther MM, Britz A, Clarke RJ, Harres K, Hoffmeister G, Nürnberg F, Otten A, Pelka A, Roth M, Vogt K.

Rev Sci Instrum. 2013 Jul;84(7):073305. doi: 10.1063/1.4815826.


Quantitative calculation of the role of the Na(+),K(+)-ATPase in thermogenesis.

Clarke RJ, Catauro M, Rasmussen HH, Apell HJ.

Biochim Biophys Acta. 2013 Oct;1827(10):1205-12. doi: 10.1016/j.bbabio.2013.06.010. Epub 2013 Jul 11.


Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, Clarke RJ, Dehghan A, Erdmann J, Ferrucci L, Hamsten A, Hofman A, Hunter DJ, Goel A, Johnson AD, Kathiresan S, Kampman E, Kiel DP, Kiemeney LA, Chambers JC, Kraft P, Lindemans J, McKnight B, Nelson CP, O'Donnell CJ, Psaty BM, Ridker PM, Rivadeneira F, Rose LM, Seedorf U, Siscovick DS, Schunkert H, Selhub J, Ueland PM, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Witteman JC, den Heijer M, Jacques P, Uitterlinden AG, Kooner JS, Rader DJ, Reilly MP, Mooser V, Chasman DI, Samani NJ, Ahmadi KR.

Am J Clin Nutr. 2013 Sep;98(3):668-76. doi: 10.3945/ajcn.112.044545. Epub 2013 Jul 3.


Redox-dependent regulation of the Na⁺-K⁺ pump: new twists to an old target for treatment of heart failure.

Liu CC, Fry NA, Hamilton EJ, Chia KK, Garcia A, Karimi Galougahi K, Figtree GA, Clarke RJ, Bundgaard H, Rasmussen HH.

J Mol Cell Cardiol. 2013 Aug;61:94-101. doi: 10.1016/j.yjmcc.2013.05.013. Epub 2013 May 30. Review.


Mechanistic and structural determinants of NMDA receptor voltage-dependent gating and slow Mg2+ unblock.

Clarke RJ, Glasgow NG, Johnson JW.

J Neurosci. 2013 Feb 27;33(9):4140-50. doi: 10.1523/JNEUROSCI.3712-12.2013.


Synthesis and supramolecular studies of chiral boronated platinum(II) complexes: insights into the molecular recognition of carboranes by β-cyclodextrin.

Ching HY, Clifford S, Bhadbhade M, Clarke RJ, Rendina LM.

Chemistry. 2012 Nov 5;18(45):14413-25. doi: 10.1002/chem.201201746. Epub 2012 Sep 25.


Rayleigh-Taylor instability of an ultrathin foil accelerated by the radiation pressure of an intense laser.

Palmer CA, Schreiber J, Nagel SR, Dover NP, Bellei C, Beg FN, Bott S, Clarke RJ, Dangor AE, Hassan SM, Hilz P, Jung D, Kneip S, Mangles SP, Lancaster KL, Rehman A, Robinson AP, Spindloe C, Szerypo J, Tatarakis M, Yeung M, Zepf M, Najmudin Z.

Phys Rev Lett. 2012 Jun 1;108(22):225002. Epub 2012 May 29.


Kinetic comparisons of heart and kidney Na+,K(+)-ATPases.

Garcia A, Rasmussen HH, Apell HJ, Clarke RJ.

Biophys J. 2012 Aug 22;103(4):677-88. doi: 10.1016/j.bpj.2012.07.032. Erratum in: Biophys J. 2013 Mar 5;104(5):1214.

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