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Coffee Ingestion Improves 5 km Cycling Performance in Men and Women by a Similar Magnitude.

Clarke ND, Kirwan NA, Richardson DL.

Nutrients. 2019 Oct 25;11(11). pii: E2575. doi: 10.3390/nu11112575.


Identifying skeletal-related events for prostate cancer patients in routinely collected hospital data.

Parry MG, Cowling TE, Sujenthiran A, Nossiter J, Berry B, Cathcart P, Clarke NW, Payne H, Aggarwal A, van der Meulen J.

Cancer Epidemiol. 2019 Nov 9;63:101628. doi: 10.1016/j.canep.2019.101628. [Epub ahead of print]


The impacts of training pathways and experiences during intern year on doctor emigration from Ireland.

Cronin F, Clarke N, Hendrick L, Conroy R, Brugha R.

Hum Resour Health. 2019 Nov 6;17(1):74. doi: 10.1186/s12960-019-0407-z.


Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling.

Eyre R, Alférez DG, Santiago-Gómez A, Spence K, McConnell JC, Hart C, Simões BM, Lefley D, Tulotta C, Storer J, Gurney A, Clarke N, Brown M, Howell SJ, Sims AH, Farnie G, Ottewell PD, Clarke RB.

Nat Commun. 2019 Nov 1;10(1):5016. doi: 10.1038/s41467-019-12807-0.


Tumor protein D54 defines a new class of intracellular transport vesicles.

Larocque G, La-Borde PJ, Clarke NI, Carter NJ, Royle SJ.

J Cell Biol. 2019 Oct 31. pii: jcb.201812044. doi: 10.1083/jcb.201812044. [Epub ahead of print]


Creatine uptake regulates CD8 T cell antitumor immunity.

Di Biase S, Ma X, Wang X, Yu J, Wang YC, Smith DJ, Zhou Y, Li Z, Kim YJ, Clarke N, To A, Yang L.

J Exp Med. 2019 Oct 18. pii: jem.20182044. doi: 10.1084/jem.20182044. [Epub ahead of print]


High-Throughput Mass Spectrometry Assay for Quantifying β-Amyloid 40 and 42 in Cerebrospinal Fluid.

Weber DM, Tran D, Goldman SM, Taylor SW, Ginns EI, Lagier RJ, Rissman RA, Brewer JB, Clarke NJ.

Clin Chem. 2019 Oct 18. pii: clinchem.2018.300947. doi: 10.1373/clinchem.2018.300947. [Epub ahead of print]


Giardia duodenalis infection in the context of a community-based deworming and water, sanitation and hygiene trial in Timor-Leste.

Aw JYH, Clarke NE, McCarthy JS, Traub RJ, Amaral S, Huque MH, Andrews RM, Gray DJ, Clements ACA, Vaz Nery S.

Parasit Vectors. 2019 Oct 18;12(1):491. doi: 10.1186/s13071-019-3752-9.


Evidence for an Association Between Hearing Impairment and Disrupted Sleep: Scoping Review.

Clarke NA, Hoare DJ, Killan EC.

Am J Audiol. 2019 Oct 17:1-10. doi: 10.1044/2019_AJA-19-0026. [Epub ahead of print]


Differential impact of mass and targeted praziquantel delivery on schistosomiasis control in school-aged children: A systematic review and meta-analysis.

Cribb DM, Clarke NE, Doi SAR, Vaz Nery S.

PLoS Negl Trop Dis. 2019 Oct 11;13(10):e0007808. doi: 10.1371/journal.pntd.0007808. eCollection 2019 Oct.


Unintended perturbation of protein function using GFP nanobodies in human cells.

Küey C, Larocque G, Clarke NI, Royle SJ.

J Cell Sci. 2019 Nov 6;132(21). pii: jcs234955. doi: 10.1242/jcs.234955.


Prostate radiotherapy in newly diagnosed metastatic prostate cancer.

Ali A, Parker CC, Clarke NW.

Curr Opin Urol. 2019 Nov;29(6):620-628. doi: 10.1097/MOU.0000000000000675.


Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial.

Clarke NW, Ali A, Ingleby FC, Hoyle A, Amos CL, Attard G, Brawley CD, Calvert J, Chowdhury S, Cook A, Cross W, Dearnaley DP, Douis H, Gilbert D, Gillessen S, Jones RJ, Langley RE, MacNair A, Malik Z, Mason MD, Matheson D, Millman R, Parker CC, Ritchie AWS, Rush H, Russell JM, Brown J, Beesley S, Birtle A, Capaldi L, Gale J, Gibbs S, Lydon A, Nikapota A, Omlin A, O'Sullivan JM, Parikh O, Protheroe A, Rudman S, Srihari NN, Simms M, Tanguay JS, Tolan S, Wagstaff J, Wallace J, Wylie J, Zarkar A, Sydes MR, Parmar MKB, James ND.

Ann Oncol. 2019 Sep 27. pii: mdz396. doi: 10.1093/annonc/mdz396. [Epub ahead of print]


A cluster-randomised controlled trial comparing school and community-based deworming for soil transmitted helminth control in school-age children: the CoDe-STH trial protocol.

Clarke NE, Ng-Nguyen D, Traub RJ, Clements ACA, Halton K, Anderson RM, Gray DJ, Coffeng LE, Kaldor JM, Vaz Nery S.

BMC Infect Dis. 2019 Sep 18;19(1):822. doi: 10.1186/s12879-019-4449-6.


Radiotherapy for metastatic prostate cancer-Authors' reply.

Parker CC, James ND, Brawley CD, Clarke NW, Parmar MKB.

Lancet. 2019 Sep 7;394(10201):830. doi: 10.1016/S0140-6736(19)31829-X. No abstract available.


Reply: Alar Cinching with Subcutaneous Flaps: A Procedure to Achieve Narrowing of the Nasal Base while Controlling the Alar Axis and Sidewall Curvature.

Clarke NA, Few J.

Plast Reconstr Surg. 2019 Sep 3. doi: 10.1097/PRS.0000000000006246. [Epub ahead of print] No abstract available.


Plate size and food consumption: a pre-registered experimental study in a general population sample.

Kosīte D, König LM, De-Loyde K, Lee I, Pechey E, Clarke N, Maynard O, Morris RW, Munafò MR, Marteau TM, Fletcher PC, Hollands GJ.

Int J Behav Nutr Phys Act. 2019 Aug 28;16(1):75. doi: 10.1186/s12966-019-0826-1.


Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer.

Hoyle AP, Ali A, James ND, Cook A, Parker CC, de Bono JS, Attard G, Chowdhury S, Cross WR, Dearnaley DP, Brawley CD, Gilson C, Ingleby F, Gillessen S, Aebersold DM, Jones RJ, Matheson D, Millman R, Mason MD, Ritchie AWS, Russell M, Douis H, Parmar MKB, Sydes MR, Clarke NW; STAMPEDE Investigators.

Eur Urol. 2019 Dec;76(6):719-728. doi: 10.1016/j.eururo.2019.08.006. Epub 2019 Aug 23.


Editorial: Fatigue and Recovery in Football.

Clarke N, Noon M.

Sports (Basel). 2019 Aug 13;7(8). pii: E192. doi: 10.3390/sports7080192.


Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma.

Melo AM, O'Brien AM, Phelan JJ, Kennedy SA, Wood NAW, Veerapen N, Besra GS, Clarke NE, Foley EK, Ravi A, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, Conroy MJ, Hogan AE, O'Sullivan J, Dunne MR.

Front Immunol. 2019 Jul 10;10:1580. doi: 10.3389/fimmu.2019.01580. eCollection 2019.


Gains and losses of metabolic function inferred from a phylotranscriptomic analysis of algae.

Goh FQY, Jeyakani J, Tipthara P, Cazenave-Gassiot A, Ghosh R, Bogard N, Yeo Z, Wong GK, Melkonian M, Wenk MR, Clarke ND.

Sci Rep. 2019 Jul 19;9(1):10482. doi: 10.1038/s41598-019-46869-3.


Wine glass size and wine sales: four replication studies in one restaurant and two bars.

Clarke N, Pechey R, Pilling M, Hollands GJ, Mantzari E, Marteau TM.

BMC Res Notes. 2019 Jul 17;12(1):426. doi: 10.1186/s13104-019-4477-8.


Restrictive Transfusion Strategy and Clinical Decision Support Practices for Reducing RBC Transfusion Overuse.

Derzon JH, Clarke N, Alford A, Gross I, Shander A, Thurer R.

Am J Clin Pathol. 2019 Oct 7;152(5):544-557. doi: 10.1093/ajcp/aqz070.


Reducing red blood cell transfusion in orthopedic and cardiac surgeries with Antifibrinolytics: A laboratory medicine best practice systematic review and meta-analysis.

Derzon JH, Clarke N, Alford A, Gross I, Shander A, Thurer R.

Clin Biochem. 2019 Sep;71:1-13. doi: 10.1016/j.clinbiochem.2019.06.015. Epub 2019 Jul 3.


Tobacco smoking and risk of 36 cardiovascular disease subtypes: fatal and non-fatal outcomes in a large prospective Australian study.

Banks E, Joshy G, Korda RJ, Stavreski B, Soga K, Egger S, Day C, Clarke NE, Lewington S, Lopez AD.

BMC Med. 2019 Jul 3;17(1):128. doi: 10.1186/s12916-019-1351-4.


Multiple primary malignancies associated with a germline SMARCB1 pathogenic variant.

Eelloo JA, Smith MJ, Bowers NL, Ealing J, Hulse P, Wylie JP, Shenjere P, Clarke NW, Soh C, Whitehouse RW, Jones M, Duff C, Freemont A, Gareth Evans D.

Fam Cancer. 2019 Oct;18(4):445-449. doi: 10.1007/s10689-019-00138-4.


Aspergillus aortitis & aortic valve endocarditis after coronary surgery.

Clarke NS, Sengupta A, Miller A, Jessen ME, Murthy RA.

J Card Surg. 2019 Sep;34(9):871-874. doi: 10.1111/jocs.14125. Epub 2019 Jun 24.


Re: David W. Donnelly, Anna Gavin, Amy Downing, et al. Regional Variations in Quality of Survival Among Men with Prostate Cancer Across the United Kingdom. Eur Urol. In press.

Clarke N, Payne H, van der Meulen J.

Eur Urol. 2019 Jun 15. pii: S0302-2838(19)30450-6. doi: 10.1016/j.eururo.2019.06.001. [Epub ahead of print] No abstract available.


Development and validation of a multiplexed-tandem qPCR tool for diagnostics of human soil-transmitted helminth infections.

Stracke K, Clarke N, Awburn CV, Vaz Nery S, Khieu V, Traub RJ, Jex AR.

PLoS Negl Trop Dis. 2019 Jun 17;13(6):e0007363. doi: 10.1371/journal.pntd.0007363. eCollection 2019 Jun.


Treatment-Related Toxicity Using Prostate-Only Versus Prostate and Pelvic Lymph Node Intensity-Modulated Radiation Therapy: A National Population-Based Study.

Parry MG, Sujenthiran A, Cowling TE, Nossiter J, Cathcart P, Clarke NW, Payne H, van der Meulen J, Aggarwal A.

J Clin Oncol. 2019 Jul 20;37(21):1828-1835. doi: 10.1200/JCO.18.02237. Epub 2019 Jun 4.


This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols.

Schiavone F, Bathia R, Letchemanan K, Masters L, Amos C, Bara A, Brown L, Gilson C, Pugh C, Atako N, Hudson F, Parmar M, Langley R, Kaplan RS, Parker C, Attard G, Clarke NW, Gillessen S, James ND, Maughan T, Sydes MR; past and present members of the STAMPEDE and FOCUS4 Trial Management Group.

Trials. 2019 May 29;20(1):264. doi: 10.1186/s13063-019-3216-8.


A qualitative interview study comparing and contrasting resident and staff perspectives of engaging in meaningful activity in a UK care home.

Clarke N, Smith R, Wood J, Koskela S, Jones F, Hurley M.

Arch Gerontol Geriatr. 2019 Jul - Aug;83:257-262. doi: 10.1016/j.archger.2019.05.005. Epub 2019 May 7.


Modeling of Entangled Polymer Diffusion in Melts and Nanocomposites: A Review.

Karatrantos A, Composto RJ, Winey KI, Kröger M, Clarke N.

Polymers (Basel). 2019 May 14;11(5). pii: E876. doi: 10.3390/polym11050876. Review.


Miscibility and Nanoparticle Diffusion in Ionic Nanocomposites.

Karatrantos A, Koutsawa Y, Dubois P, Clarke N, Kröger M.

Polymers (Basel). 2018 Sep 10;10(9). pii: E1010. doi: 10.3390/polym10091010.


Evolution of CAR T-cell immunotherapy in terms of patenting activity.

Jürgens B, Clarke NS.

Nat Biotechnol. 2019 Apr;37(4):370-375. doi: 10.1038/s41587-019-0083-5. No abstract available.


Genomic Evaluation of Multiparametric Magnetic Resonance Imaging-visible and -nonvisible Lesions in Clinically Localised Prostate Cancer.

Parry MA, Srivastava S, Ali A, Cannistraci A, Antonello J, Barros-Silva JD, Ubertini V, Ramani V, Lau M, Shanks J, Nonaka D, Oliveira P, Hambrock T, Leong HS, Dhomen N, Miller C, Brady G, Dive C, Clarke NW, Marais R, Baena E.

Eur Urol Oncol. 2019 Feb;2(1):1-11. doi: 10.1016/j.euo.2018.08.005. Epub 2018 Sep 5.


MRE11 as a Predictive Biomarker of Outcome After Radiation Therapy in Bladder Cancer.

Walker AK, Karaszi K, Valentine H, Strauss VY, Choudhury A, McGill S, Wen K, Brown MD, Ramani V, Bhattarai S, Teo MTW, Yang L, Myers KA, Deshmukh N, Denley H, Browning L, Love SB, Iyer G, Clarke NW, Hall E, Huddart R, James ND, Hoskin PJ, West CML, Kiltie AE.

Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):809-818. doi: 10.1016/j.ijrobp.2019.03.015. Epub 2019 Mar 15.


Moving healthcare professionals - a whole system approach to embed physical activity in clinical practice.

Brannan M, Bernardotto M, Clarke N, Varney J.

BMC Med Educ. 2019 Mar 15;19(1):84. doi: 10.1186/s12909-019-1517-y.


GSK3β-SCFFBXW7α mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover.

Garvin AJ, Khalaf AHA, Rettino A, Xicluna J, Butler L, Morris JR, Heery DM, Clarke NM.

Nucleic Acids Res. 2019 May 21;47(9):4476-4494. doi: 10.1093/nar/gkz163.


Does Late Hip Dysplasia Occur After Normal Ultrasound Screening in Breech Babies?

Morris AR, Thomas JMC, Reading IC, Clarke NMP.

J Pediatr Orthop. 2019 Apr;39(4):187-192. doi: 10.1097/BPO.0000000000000903.


Altered T Cell Migratory Capacity in the Progression from Barrett Oesophagus to Oesophageal Adenocarcinoma.

Kavanagh ME, Conroy MJ, Clarke NE, Gilmartin NT, Feighery R, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, O' Sullivan J, Lysaght J.

Cancer Microenviron. 2019 Apr;12(1):57-66. doi: 10.1007/s12307-019-00220-6. Epub 2019 Mar 4.


Prostate Radiotherapy for Metastatic Hormone-sensitive Prostate Cancer: A STOPCAP Systematic Review and Meta-analysis.

Burdett S, Boevé LM, Ingleby FC, Fisher DJ, Rydzewska LH, Vale CL, van Andel G, Clarke NW, Hulshof MC, James ND, Parker CC, Parmar MK, Sweeney CJ, Sydes MR, Tombal B, Verhagen PC, Tierney JF; STOPCAP M1 Radiotherapy Collaborators.

Eur Urol. 2019 Jul;76(1):115-124. doi: 10.1016/j.eururo.2019.02.003. Epub 2019 Feb 28.


What is the incidence of late detection of developmental dysplasia of the hip in England?: a 26-year national study of children diagnosed after the age of one.

Broadhurst C, Rhodes AML, Harper P, Perry DC, Clarke NMP, Aarvold A.

Bone Joint J. 2019 Mar;101-B(3):281-287. doi: 10.1302/0301-620X.101B3.BJJ-2018-1331.R1.


Risk factors for infection with soil-transmitted helminths during an integrated community level water, sanitation, and hygiene and deworming intervention in Timor-Leste.

Vaz Nery S, Clarke NE, Richardson A, Traub R, McCarthy JS, Gray DJ, Vallely AJ, Williams GM, Andrews RM, Campbell SJ, Clements ACA.

Int J Parasitol. 2019 Apr;49(5):389-396. doi: 10.1016/j.ijpara.2018.12.006. Epub 2019 Feb 22.


Active 10 - A new approach to increase physical activity in inactive people in England.

Brannan MGT, Foster CE, Timpson CM, Clarke N, Sunyer E, Amlani A, Murphy MH.

Prog Cardiovasc Dis. 2019 Mar - Apr;62(2):135-139. doi: 10.1016/j.pcad.2019.02.001. Epub 2019 Feb 21. Review.


GDPR: an impediment to research?

Clarke N, Vale G, Reeves EP, Kirwan M, Smith D, Farrell M, Hurl G, McElvaney NG.

Ir J Med Sci. 2019 Nov;188(4):1129-1135. doi: 10.1007/s11845-019-01980-2. Epub 2019 Feb 8.


Closed Reduction for Developmental Dysplasia of the Hip: Early-term Results From a Prospective, Multicenter Cohort.

Sankar WN, Gornitzky AL, Clarke NMP, Herrera-Soto JA, Kelley SP, Matheney T, Mulpuri K, Schaeffer EK, Upasani VV, Williams N, Price CT; International Hip Dysplasia Institute.

J Pediatr Orthop. 2019 Mar;39(3):111-118. doi: 10.1097/BPO.0000000000000895.


Impact of patient choice and hospital competition on patient outcomes after prostate cancer surgery: A national population-based study.

Aggarwal AK, Sujenthiran A, Lewis D, Walker K, Cathcart P, Clarke N, Sullivan R, van der Meulen JH.

Cancer. 2019 Jun 1;125(11):1898-1907. doi: 10.1002/cncr.31987. Epub 2019 Feb 1.


WASH for WORMS: A Cluster-Randomized Controlled Trial of the Impact of a Community Integrated Water, Sanitation, and Hygiene and Deworming Intervention on Soil-Transmitted Helminth Infections.

Vaz Nery S, Traub RJ, McCarthy JS, Clarke NE, Amaral S, Llewellyn S, Weking E, Richardson A, Campbell SJ, Gray DJ, Vallely AJ, Williams GM, Andrews RM, Clements ACA.

Am J Trop Med Hyg. 2019 Mar;100(3):750-761. doi: 10.4269/ajtmh.18-0705.


PF-04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo-Controlled Study.

Charnigo RJ, Beidler D, Rybin D, Pittman DD, Tan B, Howard J, Michelson AD, Frelinger AL , III, Clarke N.

Clin Transl Sci. 2019 Mar;12(2):180-188. doi: 10.1111/cts.12604. Epub 2018 Dec 31.

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