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EXPRESS: Rates of Hospitalization Associated with the use of Aldosterone Receptor Antagonists in Patients with Pulmonary Arterial Hypertension.

Corkish M, Devine L, Clarke M, Murray B, Rose-Jones L.

Pulm Circ. 2019 Jul 18:2045894019868422. doi: 10.1177/2045894019868422. [Epub ahead of print] No abstract available.


Frequency and clinical outcomes of CYP2C19 genotype-guided escalation and de-escalation of antiplatelet therapy in a real-world clinical setting.

Martin J, Williams AK, Klein MD, Sriramoju VB, Madan S, Rossi JS, Clarke M, Cicci JD, Cavallari LH, Weck KE, Stouffer GA, Lee CR.

Genet Med. 2019 Jul 18. doi: 10.1038/s41436-019-0611-1. [Epub ahead of print]


Early risk and protective factors and young adult outcomes in a longitudinal sample of young people with a history of psychotic-like experiences.

Coughlan H, Healy C, Ní Sheaghdha Á, Murray G, Humphries N, Clarke M, Cannon M.

Early Interv Psychiatry. 2019 Jul 16. doi: 10.1111/eip.12855. [Epub ahead of print]


Examining constipation assessment and management of patients with advanced cancer receiving specialist palliative care: a multi-site retrospective case note review of clinical practice.

McIlfatrick S, Muldrew DHL, Beck E, Carduff E, Clarke M, Finucane A, Graham-Wisener L, Larkin P, McCorry NK, Slater P, Hasson F.

BMC Palliat Care. 2019 Jul 15;18(1):57. doi: 10.1186/s12904-019-0436-3.


A systematic review of feasibility studies promoting the use of mobile technologies in clinical research.

Bakker JP, Goldsack JC, Clarke M, Coravos A, Geoghegan C, Godfrey A, Heasley MG, Karlin DR, Manta C, Peterson B, Ramirez E, Sheth N, Bruno A, Bullis E, Wareham K, Zimmerman N, Forrest A, Wood WA.

NPJ Digit Med. 2019 Jun 6;2:47. doi: 10.1038/s41746-019-0125-x. eCollection 2019.


Clinical presentation, management and outcomes of sacral metastases: a multicenter, retrospective cohort study.

Charest-Morin R, Fisher CG, Versteeg AL, Sahgal A, Varga PP, Sciubba DM, Schuster JM, Weber MH, Clarke MJ, Rhines LD, Boriani S, Bettegowda C, Fehlings MG, Arnold PM, Gokaslan ZL, Dea N.

Ann Transl Med. 2019 May;7(10):214. doi: 10.21037/atm.2019.04.88.


Key Worker-Mediated Enhancement of Physical Health in First Episode Psychosis: Protocol For a Feasibility Study in Primary Care.

McCombe G, Harrold A, Brown K, Hennessy L, Clarke M, Hanlon D, O'Brien S, Lyne J, Corcoran C, McGorry P, Cullen W.

JMIR Res Protoc. 2019 Jul 10;8(7):e13115. doi: 10.2196/13115.


Prioritization of Outcomes in Efficacy and Effectiveness of Alcohol Brief Intervention Trials: International Multi-Stakeholder e-Delphi Consensus Study to Inform a Core Outcome Set.

Shorter GW, Heather N, Bray JW, Berman AH, Giles EL, O'Donnell AJ, Barbosa C, Clarke M, Holloway A, Newbury-Birch D.

J Stud Alcohol Drugs. 2019 May;80(3):299-309.


The Variability of Outcomes Used in Efficacy and Effectiveness Trials of Alcohol Brief Interventions: A Systematic Review.

Shorter GW, Bray JW, Giles EL, O'Donnell AJ, Berman AH, Holloway A, Heather N, Barbosa C, Stockdale KJ, Scott SJ, Clarke M, Newbury-Birch D.

J Stud Alcohol Drugs. 2019 May;80(3):286-298.


Vascular smooth muscle cells in atherosclerosis.

Basatemur GL, Jørgensen HF, Clarke MCH, Bennett MR, Mallat Z.

Nat Rev Cardiol. 2019 Jun 26. doi: 10.1038/s41569-019-0227-9. [Epub ahead of print] Review.


Pulpotomy for mature carious teeth with symptoms of irreversible pulpitis: A systematic review.

Cushley S, Duncan HF, Lappin MJ, Tomson PL, Lundy FT, Cooper P, Clarke M, El Karim IA.

J Dent. 2019 Jun 20. pii: S0300-5712(19)30129-0. doi: 10.1016/j.jdent.2019.06.005. [Epub ahead of print] Review.


Death Is Coming and the Clot Thickens, as Pyroptosis Feeds the Fire.

Burzynski LC, Clarke MCH.

Immunity. 2019 Jun 18;50(6):1339-1341. doi: 10.1016/j.immuni.2019.05.015.


How Effective Is the Multidisciplinary Team Approach in Bariatric Surgery?

Bullen NL, Parmar J, Gilbert J, Clarke M, Cota A, Finlay IG.

Obes Surg. 2019 Jun 17. doi: 10.1007/s11695-019-03975-5. [Epub ahead of print]


Senescence utilises inflammatory caspases to drive the SASP.

Wiggins KA, Clarke MC.

Aging (Albany NY). 2019 Jun 17;11(12):3891-3892. doi: 10.18632/aging.102031. No abstract available.


Overlooked Minorities: The Intersection of Cancer in Lesbian, Gay, Bisexual, Transgender, and/or Intersex Adolescents and Young Adults.

Clarke M, Lewin J, Lazarakis S, Thompson K.

J Adolesc Young Adult Oncol. 2019 Jun 14. doi: 10.1089/jayao.2019.0021. [Epub ahead of print] No abstract available.


A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research priorities in response to outbreaks-results from the Lassa fever pilot.

Sigfrid L, Moore C, Salam AP, Maayan N, Hamel C, Garritty C, Lutje V, Buckley B, Soares-Weiser K, Marshall R, Clarke M, Horby P.

BMC Med. 2019 Jun 11;17(1):107. doi: 10.1186/s12916-019-1338-1.


Clinical and Therapeutic Implications of Cancer Stem Cells.

Clarke MF.

N Engl J Med. 2019 Jun 6;380(23):2237-2245. doi: 10.1056/NEJMra1804280. Review. No abstract available.


Molecular biomarkers and precision medicine in colorectal cancer: a systematic review of health economic analyses.

Henderson R, French D, Sullivan R, Maughan T, Clarke M, Lawler M.

Oncotarget. 2019 May 21;10(36):3408-3423. doi: 10.18632/oncotarget.26909. eCollection 2019 May 21. Review.


Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer.

Kohrt HE, Houot R, Weiskopf K, Goldstein MJ, Scheeren F, Czerwinski D, Colevas AD, Weng WK, Clarke MF, Carlson RW, Stockdale FE, Mollick JA, Chen L, Levy R.

J Clin Invest. 2019 Jun 3;129(6):2595. doi: 10.1172/JCI129688. Epub 2019 Jun 3. No abstract available.


Retrieval of individual patient data depended on study characteristics: a randomized controlled trial.

Veroniki AA, Ashoor HM, Le SPC, Rios P, Stewart LA, Clarke M, Mavridis D, Straus SE, Tricco AC.

J Clin Epidemiol. 2019 May 30;113:176-188. doi: 10.1016/j.jclinepi.2019.05.031. [Epub ahead of print]


Oral hygiene interventions for people with intellectual disabilities.

Waldron C, Nunn J, Mac Giolla Phadraig C, Comiskey C, Guerin S, van Harten MT, Donnelly-Swift E, Clarke MJ.

Cochrane Database Syst Rev. 2019 May 31;5:CD012628. doi: 10.1002/14651858.CD012628.pub2. Review.


A versatile method for assessing pathogenicity of Hymenoscyphus fraxineus to ash foliage.

Orton ES, Clarke M, Brasier CM, Webber JF, Brown JKM.

For Pathol. 2019 Apr;49(2):e12484. doi: 10.1111/efp.12484. Epub 2018 Dec 14.


Hysterectomy-Corrected Uterine Corpus Cancer Incidence Trends and Differences in Relative Survival Reveal Racial Disparities and Rising Rates of Nonendometrioid Cancers.

Clarke MA, Devesa SS, Harvey SV, Wentzensen N.

J Clin Oncol. 2019 May 22:JCO1900151. doi: 10.1200/JCO.19.00151. [Epub ahead of print]


National action plans to tackle NCDs: role of stakeholder network analysis.

Hunter RF, Wickramasinghe K, Ergüder T, Bolat A, Arı HO, Yıldırım HH, Ursu P, Robinson G, Breda J, Mikkelsen B, Connolly P, Clarke M, Kee F.

BMJ. 2019 May 20;365:l1871. doi: 10.1136/bmj.l1871. No abstract available.


ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma.

Carvalho D, Taylor KR, Olaciregui NG, Molinari V, Clarke M, Mackay A, Ruddle R, Henley A, Valenti M, Hayes A, Brandon AH, Eccles SA, Raynaud F, Boudhar A, Monje M, Popov S, Moore AS, Mora J, Cruz O, Vinci M, Brennan PE, Bullock AN, Carcaboso AM, Jones C.

Commun Biol. 2019 May 9;2:156. doi: 10.1038/s42003-019-0420-8. eCollection 2019.


Childhood adversity and adolescent psychopathology: evidence for mediation in a national longitudinal cohort study.

Dhondt N, Healy C, Clarke M, Cannon M.

Br J Psychiatry. 2019 May 16:1-6. doi: 10.1192/bjp.2019.108. [Epub ahead of print]


Childhood and adolescent psychotic experiences and risk of mental disorder: a systematic review and meta-analysis.

Healy C, Brannigan R, Dooley N, Coughlan H, Clarke M, Kelleher I, Cannon M.

Psychol Med. 2019 Jul;49(10):1589-1599. doi: 10.1017/S0033291719000485. Epub 2019 May 15.


Clinical Evaluation of Human Papillomavirus Screening With p16/Ki-67 Dual Stain Triage in a Large Organized Cervical Cancer Screening Program.

Wentzensen N, Clarke MA, Bremer R, Poitras N, Tokugawa D, Goldhoff PE, Castle PE, Schiffman M, Kingery JD, Grewal KK, Locke A, Kinney W, Lorey TS.

JAMA Intern Med. 2019 May 13. doi: 10.1001/jamainternmed.2019.0306. [Epub ahead of print] Erratum in: JAMA Intern Med. 2019 Jul 1;179(7):1007.


Iliac Fenestration-An Alternative Endovascular Option for Common Iliac Aneurysms.

Mafeld S, Lakshminarayan R, Kim CN, Clarke M, Williams R.

Ann Vasc Surg. 2019 May 8. pii: S0890-5096(19)30300-0. doi: 10.1016/j.avsg.2019.02.044. [Epub ahead of print]


The iHOPE-20 study: mortality in first episode psychosis-a 20-year follow-up of the Dublin first episode cohort.

Doyle R, O'Keeffe D, Hannigan A, Kinsella A, Behan C, Kelly A, Sheridan A, Madigan K, Lawlor E, Clarke M.

Soc Psychiatry Psychiatr Epidemiol. 2019 May 9. doi: 10.1007/s00127-019-01721-x. [Epub ahead of print]


Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone.

Skinner-Adams TS, Fisher GM, Riches AG, Hutt OE, Jarvis KE, Wilson T, von Itzstein M, Chopra P, Antonova-Koch Y, Meister S, Winzeler EA, Clarke M, Fidock DA, Burrows JN, Ryan JH, Andrews KT.

Commun Biol. 2019 May 3;2:166. doi: 10.1038/s42003-019-0397-3. eCollection 2019.


A randomized trial to assess beverage hydration index in healthy older adults.

Clarke MM, Stanhewicz AE, Wolf ST, Cheuvront SN, Kenefick RW, Kenney WL.

Am J Clin Nutr. 2019 Jun 1;109(6):1640-1647. doi: 10.1093/ajcn/nqz009.


Improving the science and evidence base of disaster response: a policy research study.

Jillson IA, Clarke M, Allen C, Waller S, Koehlmoos T, Mumford W, Jansen J, McKay K, Trant A.

BMC Health Serv Res. 2019 May 2;19(1):274. doi: 10.1186/s12913-019-4102-5.


Does Difference in Physical Activity Between Blacks and Whites Vary by Sex, Income, Education, and Region of Residence? Results from 2008 to 2017 National Health Interview Surveys.

Siahpush M, Robbins RE, Ramos AK, Michaud TL, Clarke MA, King KM.

J Racial Ethn Health Disparities. 2019 Apr 19. doi: 10.1007/s40615-019-00586-9. [Epub ahead of print]


An outreach program with hands-on, physiology-based exercises generates questions about STEM career expectations.

Clarke MA, Sharma NM, Schiller AM.

Adv Physiol Educ. 2019 Jun 1;43(2):175-179. doi: 10.1152/advan.00013.2019.


Changes in soluble tumor necrosis factor receptor type 1 levels and early renal function decline in patients with diabetes.

MacIsaac RJ, Farag M, Obeyesekere V, Clarke M, Boston R, Ward GM, Jerums G, Ekinci EI.

J Diabetes Investig. 2019 Apr 15. doi: 10.1111/jdi.13061. [Epub ahead of print]


Prognostic significance of hTERT (human telomerase reverse transcriptase) promoter region mutations C228T and C250T for overall survival in spinal chordomas.

Bettegowda C, Yip S, Jiang B, Wang WL, Clarke MJ, Lazary A, Gambarotti M, Zhang M, Sciubba DM, Wolinsky JP, Goodwin CR, McCarthy E, Germscheid NM, Sahgal A, Gokaslan ZL, Boriani S, Varga PP, Fisher CG, Rhines LD.

Neuro Oncol. 2019 Apr 12. pii: noz066. doi: 10.1093/neuonc/noz066. [Epub ahead of print]


Legislation targeting head shops selling new psychoactive substances and changes in drug-related psychiatric admissions: A national database study.

Smyth BP, Daly A, Elmusharaf K, McDonald C, Clarke M, Craig S, Cullen W.

Early Interv Psychiatry. 2019 Apr 4. doi: 10.1111/eip.12807. [Epub ahead of print]


Linking Inuit Knowledge and Public Health for Improved Child and Youth Oral Health in NunatuKavut.

Martin D, McNally M, Castleden H, Worden-Driscoll I, Clarke M, Wall D, Ley M.

JDR Clin Trans Res. 2018 Jul;3(3):256-263. doi: 10.1177/2380084418767833. Epub 2018 Apr 9.


Assessing Online Flow Across Cultures: A Two-Fold Measurement Invariance Study.

Hu E, Stavropoulos V, Anderson A, Clarke M, Beard C, Papapetrou S, Gomez R.

Front Psychol. 2019 Mar 15;10:407. doi: 10.3389/fpsyg.2019.00407. eCollection 2019.


Resilience in medical doctors: a systematic review.

McKinley N, Karayiannis PN, Convie L, Clarke M, Kirk SJ, Campbell WJ.

Postgrad Med J. 2019 Mar;95(1121):140-147. doi: 10.1136/postgradmedj-2018-136135. Epub 2019 Mar 29.


The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin.

Burzynski LC, Humphry M, Pyrillou K, Wiggins KA, Chan JNE, Figg N, Kitt LL, Summers C, Tatham KC, Martin PB, Bennett MR, Clarke MCH.

Immunity. 2019 Apr 16;50(4):1033-1042.e6. doi: 10.1016/j.immuni.2019.03.003. Epub 2019 Mar 26.


Labour characteristics of women achieving successful vaginal birth after caesarean section in three European countries.

Grylka-Baeschlin S, Clarke M, Begley C, Daly D, Healy P, Nicoletti J, Devane D, Morano S, Krause G, Karch A, Savage G, Gross MM.

Midwifery. 2019 Jul;74:36-43. doi: 10.1016/j.midw.2019.03.013. Epub 2019 Mar 19.


IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype.

Wiggins KA, Parry AJ, Cassidy LD, Humphry M, Webster SJ, Goodall JC, Narita M, Clarke MCH.

Aging Cell. 2019 Jun;18(3):e12946. doi: 10.1111/acel.12946. Epub 2019 Mar 27.


Identification of new Wilms tumour predisposition genes: an exome sequencing study.

Mahamdallie S, Yost S, Poyastro-Pearson E, Holt E, Zachariou A, Seal S, Elliott A, Clarke M, Warren-Perry M, Hanks S, Anderson J, Bomken S, Cole T, Farah R, Furtwaengler R, Glaser A, Grundy R, Hayden J, Lowis S, Millot F, Nicholson J, Ronghe M, Skeen J, Williams D, Yeomanson D, Ruark E, Rahman N.

Lancet Child Adolesc Health. 2019 May;3(5):322-331. doi: 10.1016/S2352-4642(19)30018-5. Epub 2019 Mar 16.


Incorporating Quality Improvement into Resident Education: Structured Curriculum, Evaluation, and Quality Improvement Projects.

Clarke MJ, Steffens FL, Mallory GW, Starr SR, Porter BL, Krauss WE, Dankbar EC.

World Neurosurg. 2019 Mar 14. pii: S1878-8750(19)30692-8. doi: 10.1016/j.wneu.2019.02.214. [Epub ahead of print]


Dependence on Myb expression is attenuated in myeloid leukaemia with N-terminal CEBPA mutations.

Volpe G, Cauchy P, Walton DS, Ward C, Blakemore D, Bayley R, Clarke ML, Schmidt L, Nerlov C, Garcia P, Dumon S, Grebien F, Frampton J.

Life Sci Alliance. 2019 Mar 15;2(2). pii: e201800207. doi: 10.26508/lsa.201800207. Print 2019 Apr.


MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment.

Zormpas-Petridis K, Jerome NP, Blackledge MD, Carceller F, Poon E, Clarke M, McErlean CM, Barone G, Koers A, Vaidya SJ, Marshall LV, Pearson ADJ, Moreno L, Anderson J, Sebire N, McHugh K, Koh DM, Yuan Y, Chesler L, Robinson SP, Jamin Y.

Cancer Res. 2019 Jun 1;79(11):2978-2991. doi: 10.1158/0008-5472.CAN-18-3412. Epub 2019 Mar 15.


Prospective Evaluation of Radiculitis following Bone Morphogenetic Protein-2 Use for Transforaminal Interbody Arthrodesis in Spine Surgery.

Sebastian AS, Wanderman NR, Currier BL, Pichelmann MA, Treder VM, Fogelson JL, Clarke MJ, Nassr AN.

Asian Spine J. 2019 Mar 15. doi: 10.31616/asj.2018.0277. [Epub ahead of print]

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