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Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review.

Rose L, Agar M, Burry L, Campbell N, Clarke M, Lee J, Marshall J, Siddiqi N, Page V; Development of Core Outcome Sets for Effectiveness Trials of Interventions to Prevent and/or Treat Delirium (Del-COrS) Group.

Crit Care Med. 2020 Apr;48(4):e316-e324. doi: 10.1097/CCM.0000000000004238.


Molecular and immunological features of a prolonged exceptional responder with malignant pleural mesothelioma treated initially and rechallenged with pembrolizumab.

Minchom A, Yuan W, Crespo M, Gurel B, Figueiredo I, Wotherspoon A, Miranda S, Riisnaes R, Ferreira A, Bertan C, Pereira R, Clarke M, Baker C, Ang JE, Fotiadis N, Tunariu N, Carreira S, Popat S, O'Brien M, Banerji U, de Bono J, Lopez J.

J Immunother Cancer. 2020 Mar;8(1). pii: e000713. doi: 10.1136/jitc-2020-000713.


Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review.

Rose L, Agar M, Burry L, Campbell N, Clarke M, Lee J, Marshall J, Siddiqi N, Page V; Development of Core Outcome Sets for Effectiveness Trials of Interventions to Prevent and/or Treat Delirium (Del-COrS) Group.

Crit Care Med. 2020 Feb 20. doi: 10.1097/CCM.0000000000004238. [Epub ahead of print]


Urban American Indian Community Health Beliefs Associated with Addressing Cancer in the Northern Plains Region.

Idoate R, Gilbert M, King KM, Spellman L, McWilliams B, Strong B, Bronner L, Siahpush M, Ramos AK, Clarke M, Michaud T, Godfrey M, Solheim J.

J Cancer Educ. 2020 Mar 11. doi: 10.1007/s13187-020-01727-z. [Epub ahead of print]


Socio-ecological connectivity differs in magnitude and direction across urban landscapes.

Egerer M, Fouch N, Anderson EC, Clarke M.

Sci Rep. 2020 Mar 6;10(1):4252. doi: 10.1038/s41598-020-61230-9.


OptiBIRTH: a cluster randomised trial of a complex intervention to increase vaginal birth after caesarean section.

Clarke M, Devane D, Gross MM, Morano S, Lundgren I, Sinclair M, Putman K, Beech B, Vehviläinen-Julkunen K, Nieuwenhuijze M, Wiseman H, Smith V, Daly D, Savage G, Newell J, Simpkin A, Grylka-Baeschlin S, Healy P, Nicoletti J, Lalor J, Carroll M, van Limbeek E, Nilsson C, Stockdale J, Fobelets M, Begley C.

BMC Pregnancy Childbirth. 2020 Mar 6;20(1):143. doi: 10.1186/s12884-020-2829-y.


The role of key workers in improving physical health in first episode psychosis: A scoping review.

Lim J, McCombe G, Harrold A, Brown K, Clarke M, Hanlon D, Hennessy L, O'Brien S, Lyne J, Corcoran C, McGorry P, Cullen W.

Early Interv Psychiatry. 2020 Mar 5. doi: 10.1111/eip.12937. [Epub ahead of print] Review.


Saliva for Assessing Vitamin A Status in Extremely Preterm Infants: A Diagnostic Study.

Rakshasbhuvankar AA, Clarke MW, Simmer K, Patole SK, Pillow JJ.

Neonatology. 2020 Feb 28:1-4. doi: 10.1159/000506132. [Epub ahead of print]


Physical health among patients with common mental health disorders in primary care in Europe: a scoping review.

Fogarty F, McCombe G, Brown K, Van Amelsvoort T, Clarke M, Cullen W.

Ir J Psychol Med. 2020 Feb 28:1-17. doi: 10.1017/ipm.2020.2. [Epub ahead of print]


Modifiable Lifestyle and Medical Risk Factors Associated With Myeloproliferative Neoplasms.

Duncombe AS, Anderson LA, James G, de Vocht F, Fritschi L, Mesa R, Clarke M, McMullin MF.

Hemasphere. 2020 Jan 3;4(1):e327. doi: 10.1097/HS9.0000000000000327. eCollection 2020 Feb.


Dose of budesonide with surfactant affects lung and systemic inflammation after normal and injurious ventilation in preterm lambs.

Hillman NH, Abugisisa L, Royse E, Fee E, Kemp MW, Kramer BW, Schmidt AF, Salomone F, Clarke MW, Musk GC, Jobe AH.

Pediatr Res. 2020 Feb 17. doi: 10.1038/s41390-020-0809-6. [Epub ahead of print]


A qualitative study of the factors influencing recruitment to a pilot trial on the prevention of striae gravidarum.

Brennan M, Clarke M, Devane D, Dowling M.

BMC Pregnancy Childbirth. 2020 Feb 12;20(1):103. doi: 10.1186/s12884-020-2781-x.


Anticipatory care planning intervention for older adults at risk of functional decline: study protocol for a primary care cluster feasibility randomised trial.

Brazil K, Scott D, Wallace E, Clarke M, Fahey T, Gillespie P, O'Halloran P, Cardwell C, Carter G, McGlade K, Doyle F.

Trials. 2020 Feb 11;21(1):168. doi: 10.1186/s13063-020-4100-2.


The role of prenatal stress as a pathway to personality disorder: longitudinal birth cohort study - CORRIGENDUM.

Brannigan R, Tanskanen A, Huttunen MO, Cannon M, Leacy FP, Clarke MC.

Br J Psychiatry. 2020 Feb 11:1. doi: 10.1192/bjp.2020.50. [Epub ahead of print] No abstract available.


Identification of HPV genotypes causing cervical precancer using tissue-based genotyping.

Venetianer R, Clarke MA, van der Marel J, Tota J, Schiffman M, Dunn ST, Walker J, Zuna R, Quint W, Wentzensen N.

Int J Cancer. 2020 May 15;146(10):2836-2844. doi: 10.1002/ijc.32919. Epub 2020 Feb 22.


Risk and protective factors for psychotic experiences in adolescence: a population-based study.

McMahon EM, Corcoran P, Keeley H, Clarke M, Coughlan H, Wasserman D, Hoven CW, Carli V, Sarchiapone M, Healy C, Cannon M.

Psychol Med. 2020 Feb 6:1-9. doi: 10.1017/S0033291719004136. [Epub ahead of print]


A modified Camel and Cactus Test detects presymptomatic semantic impairment in genetic frontotemporal dementia within the GENFI cohort.

Moore K, Convery R, Bocchetta M, Neason M, Cash DM, Greaves C, Russell LL, Clarke MTM, Peakman G, van Swieten J, Jiskoot L, Moreno F, Barandiaran M, Sanchez-Valle R, Borroni B, Laforce R Jr, Doré MC, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Karnath HO, Vandenberghe R, de Mendonça A, Maruta C, Tagliavini F, Santana I, Ducharme S, Butler C, Gerhard A, Levin J, Danek A, Otto M, Warren JD, Rohrer JD; Genetic FTD Initiative, GENFI.

Appl Neuropsychol Adult. 2020 Feb 5:1-8. doi: 10.1080/23279095.2020.1716357. [Epub ahead of print]


Ultrasound detection of endometrial cancer in women with postmenopausal bleeding: Systematic review and meta-analysis.

Long B, Clarke MA, Morillo ADM, Wentzensen N, Bakkum-Gamez JN.

Gynecol Oncol. 2020 Jan 30. pii: S0090-8258(20)30085-8. doi: 10.1016/j.ygyno.2020.01.032. [Epub ahead of print] Review.


Surgical or Radiation Therapy for the Treatment of Cervical Spine Metastases: Results From the Epidemiology, Process, and Outcomes of Spine Oncology (EPOSO) Cohort.

Bond MR, Versteeg AL, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Fehlings MG, Lazary A, Clarke MJ, Boriani S, Bettegowda C, Arnold PM, Gokaslan ZL, Fisher CG.

Global Spine J. 2020 Feb;10(1):21-29. doi: 10.1177/2192568219839407. Epub 2019 Mar 31.


Introduction of PCR testing reveals a previously unrecognized burden of yersiniosis in Hampshire, UK.

Clarke M, Dabke G, Strakova L, Jenkins C, Saavedra-Campos M, McManus O, Paranthaman K.

J Med Microbiol. 2020 Jan 30. doi: 10.1099/jmm.0.001125. [Epub ahead of print]


Resilience, burnout and coping mechanisms in UK doctors: a cross-sectional study.

McKinley N, McCain RS, Convie L, Clarke M, Dempster M, Campbell WJ, Kirk SJ.

BMJ Open. 2020 Jan 27;10(1):e031765. doi: 10.1136/bmjopen-2019-031765.


Prenatal exposure to valproic acid reduces social responses and alters mRNA levels of opioid receptor and pre-pro-peptide in discrete brain regions of adolescent and adult male rats.

Hughes EM, Calcagno P, Clarke M, Sanchez C, Smith K, Kelly JP, Finn DP, Roche M.

Brain Res. 2020 Apr 1;1732:146675. doi: 10.1016/j.brainres.2020.146675. Epub 2020 Jan 21.


Single-cell transcriptional diversity is a hallmark of developmental potential.

Gulati GS, Sikandar SS, Wesche DJ, Manjunath A, Bharadwaj A, Berger MJ, Ilagan F, Kuo AH, Hsieh RW, Cai S, Zabala M, Scheeren FA, Lobo NA, Qian D, Yu FB, Dirbas FM, Clarke MF, Newman AM.

Science. 2020 Jan 24;367(6476):405-411. doi: 10.1126/science.aax0249.


Fool's gold? Why blinded trials are not always best.

Anand R, Norrie J, Bradley JM, McAuley DF, Clarke M.

BMJ. 2020 Jan 21;368:l6228. doi: 10.1136/bmj.l6228. No abstract available.


The research burden of randomized controlled trial participation: a systematic thematic synthesis of qualitative evidence.

Naidoo N, Nguyen VT, Ravaud P, Young B, Amiel P, Schanté D, Clarke M, Boutron I.

BMC Med. 2020 Jan 20;18(1):6. doi: 10.1186/s12916-019-1476-5.


Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk.

Cassidy LD, Young ARJ, Young CNJ, Soilleux EJ, Fielder E, Weigand BM, Lagnado A, Brais R, Ktistakis NT, Wiggins KA, Pyrillou K, Clarke MCH, Jurk D, Passos JF, Narita M.

Nat Commun. 2020 Jan 16;11(1):307. doi: 10.1038/s41467-019-14187-x.


Analytical Bias in the Measurement of Plasma 25-Hydroxyvitamin D Concentrations in Infants.

Rueter K, Black LJ, Jones A, Bulsara M, Clarke MW, Gamez C, Lim EM, Palmer DJ, Prescott SL, Siafarikas A.

Int J Environ Res Public Health. 2020 Jan 8;17(2). pii: E412. doi: 10.3390/ijerph17020412.


Sleep disturbance: a potential target to improve symptoms and quality of life in those living with psychosis.

Boland C, Gallagher P, Clarke M.

Ir J Psychol Med. 2020 Jan 14:1-6. doi: 10.1017/ipm.2019.58. [Epub ahead of print]


Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV.

Sheahan TP, Sims AC, Leist SR, Schäfer A, Won J, Brown AJ, Montgomery SA, Hogg A, Babusis D, Clarke MO, Spahn JE, Bauer L, Sellers S, Porter D, Feng JY, Cihlar T, Jordan R, Denison MR, Baric RS.

Nat Commun. 2020 Jan 10;11(1):222. doi: 10.1038/s41467-019-13940-6.


Loperamide overdose causing torsades de pointes and requiring Impella temporary mechanical support: a case report.

Cicci JD, Jagielski SM, Clarke MM, Rayson RA, Cavender MA.

Eur Heart J Case Rep. 2019 Dec;3(4):1-6. doi: 10.1093/ehjcr/ytz150. Epub 2019 Sep 27.


Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed.

Treweek S, Bevan S, Bower P, Briel M, Campbell M, Christie J, Collett C, Cotton S, Devane D, El Feky A, Galvin S, Gardner H, Gillies K, Hood K, Jansen J, Littleford R, Parker A, Ramsay C, Restrup L, Sullivan F, Torgerson D, Tremain L, von Elm E, Westmore M, Williams H, Williamson PR, Clarke M.

Trials. 2020 Jan 7;21(1):33. doi: 10.1186/s13063-019-3980-5.


Genomics of lethal prostate cancer at diagnosis and castration resistance.

Mateo J, Seed G, Bertan C, Rescigno P, Dolling D, Figueiredo I, Miranda S, Nava Rodrigues D, Gurel B, Clarke M, Atkin M, Chandler R, Messina C, Sumanasuriya S, Bianchini D, Barrero M, Petermolo A, Zafeirou Z, Fontes M, Perez-Lopez R, Tunariu N, Fulton B, Jones R, McGovern U, Ralph C, Varughese M, Parikh O, Jain S, Elliott T, Sandhu S, Porta N, Hall E, Yuan W, Carreira S, de Bono JS.

J Clin Invest. 2020 Feb 24. pii: 132031. doi: 10.1172/JCI132031. [Epub ahead of print]


Patients and Caregivers Helping to Shape the Undergraduate Pharmacy Mental Health Curriculum.

Keating D, McWilliams S, Hynes C, Purcell A, Clarke M, Strawbridge J.

Am J Pharm Educ. 2019 Nov;83(9):7138. doi: 10.5688/ajpe7138.


Socio-demographic predictors of well-being in United Kingdom adolescents, and the impact of well-being on a range of health-related outcomes.

McKay MT, Andretta JR, Cole JC, Clarke M.

Psychiatry Res. 2020 Mar;285:112728. doi: 10.1016/j.psychres.2019.112728. Epub 2019 Dec 4.


A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial.

Bradley JM, Anand R, O'Neill B, Ferguson K, Clarke M, Carroll M, Chalmers J, De Soyza A, Duckers J, Hill AT, Loebinger MR, Copeland F, Gardner E, Campbell C, Agus A, McGuire A, Boyle R, McKinney F, Dickson N, McAuley DF, Elborn S; CLEAR study group.

Trials. 2019 Dec 19;20(1):747. doi: 10.1186/s13063-019-3766-9.


CSF synaptic protein concentrations are raised in those with atypical Alzheimer's disease but not frontotemporal dementia.

Clarke MTM, Brinkmalm A, Foiani MS, Woollacott IOC, Heller C, Heslegrave A, Keshavan A, Fox NC, Schott JM, Warren JD, Blennow K, Zetterberg H, Rohrer JD.

Alzheimers Res Ther. 2019 Dec 17;11(1):105. doi: 10.1186/s13195-019-0564-2.


Births and deaths must be registered in Africa.

Sankoh O, Dickson KE, Faniran S, Lahai JI, Forna F, Liyosi E, Kamara MK, Jabbi SB, Johnny AB, Conteh-Khali N, Bangali A, Kangbai JB, Bockarie T, Massaquoi MM, Smart F, Jambai A, Clarke M, Dlamini A, Lehohla P, Weston M.

Lancet Glob Health. 2020 Jan;8(1):e33-e34. doi: 10.1016/S2214-109X(19)30442-5. No abstract available.


Childhood temperament and its association with adult psychiatric disorders in a prospective cohort study.

Brannigan R, Cannon M, Tanskanen A, Huttunen MO, Leacy FP, Clarke MC.

Schizophr Res. 2019 Dec 5. pii: S0920-9964(19)30562-6. doi: 10.1016/j.schres.2019.11.055. [Epub ahead of print]


Royal College of Physicians of Edinburgh, James Lind Library and fair tests of treatment.

Clarke M, Ravindran V.

J R Coll Physicians Edinb. 2019 Dec;49(4):267-268. doi: 10.4997/JRCPE.2019.401. No abstract available.


Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial.

Mateo J, Porta N, Bianchini D, McGovern U, Elliott T, Jones R, Syndikus I, Ralph C, Jain S, Varughese M, Parikh O, Crabb S, Robinson A, McLaren D, Birtle A, Tanguay J, Miranda S, Figueiredo I, Seed G, Bertan C, Flohr P, Ebbs B, Rescigno P, Fowler G, Ferreira A, Riisnaes R, Pereira R, Curcean A, Chandler R, Clarke M, Gurel B, Crespo M, Nava Rodrigues D, Sandhu S, Espinasse A, Chatfield P, Tunariu N, Yuan W, Hall E, Carreira S, de Bono JS.

Lancet Oncol. 2020 Jan;21(1):162-174. doi: 10.1016/S1470-2045(19)30684-9. Epub 2019 Dec 2.


DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.

Pickles JC, Fairchild AR, Stone TJ, Brownlee L, Merve A, Yasin SA, Avery A, Ahmed SW, Ogunbiyi O, Gonzalez Zapata J, Peary AF, Edwards M, Wilkhu L, Dryden C, Ladon D, Kristiansen M, Rowe C, Kurian KM, Nicoll JAR, Mitchell C, Bloom T, Hilton DA, Al-Sarraj S, Doey L, Johns PN, Bridges LR, Chakrabarty A, Ismail A, Rathi N, Syed K, Lammie GA, Limback-Stanic C, Smith C, Torgersen A, Rae F, Hill RM, Clifford SC, Grabovska Y, Williamson D, Clarke M, Jones C, Capper D, Sill M, von Deimling A, Pfister SM, Jones DTW, Hargrave D, Chalker J, Jacques TS.

Lancet Child Adolesc Health. 2020 Feb;4(2):121-130. doi: 10.1016/S2352-4642(19)30342-6. Epub 2019 Nov 27. Erratum in: Lancet Child Adolesc Health. 2019 Dec 23;:.


Program completion and glycemic control in a remote patient monitoring program for diabetes management: Does gender matter?

Michaud TL, Siahpush M, King KM, Ramos AK, Robbins RE, Schwab RJ, Clarke MA, Su D.

Diabetes Res Clin Pract. 2020 Jan;159:107944. doi: 10.1016/j.diabres.2019.107944. Epub 2019 Nov 23.


Aspirin for the Primary Prevention of Cardiovascular Disease: A Review of the Literature and Considerations for Clinical Practice.

Cicci JD, Iyer P, Clarke MM, Mazzella AJ.

Cardiol Rev. 2020 Mar/Apr;28(2):98-106. doi: 10.1097/CRD.0000000000000297.


Education and epilepsy: Examples of good practice and cooperation. Report of the IBE Commission on Education.

Braga P, Mifsud J, D'Souza C, Clarke M, Honein A, Tovuudorj A, Pfäfflin M.

Epilepsy Behav. 2020 Feb;103(Pt A):106653. doi: 10.1016/j.yebeh.2019.106653. Epub 2019 Nov 21. Review.


A prospective clinical cohort study of women at increased risk for endometrial cancer.

Clarke MA, Long BJ, Sherman ME, Lemens MA, Podratz KC, Hopkins MR, Ahlberg LJ, Mc Guire LJ, Laughlin-Tommaso SK, Wentzensen N, Bakkum-Gamez JN.

Gynecol Oncol. 2020 Jan;156(1):169-177. doi: 10.1016/j.ygyno.2019.09.014. Epub 2019 Nov 9.


Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial.

Blackwood B, Agus A, Boyle R, Clarke M, Hemming K, Jordan J, Macrae D, McAuley DF, McDowell C, McIlmurray L, Morris KP, Murray M, Parslow R, Peters MJ, Tume LN, Walsh T; Paediatric Intensive Care Society Study Group (PICS-SG).

BMJ Open. 2019 Nov 10;9(11):e031630. doi: 10.1136/bmjopen-2019-031630.


Corrigendum to "The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva" [J. Steroid Biochem. Mol. Biol. 194 (2019) 105437].

Clarke MW, Black LJ, Hart PH, Jones AP, Palmer DJ, Siafarikas A, Lucas RM, Gorman S.

J Steroid Biochem Mol Biol. 2019 Nov 8:105474. doi: 10.1016/j.jsbmb.2019.105474. [Epub ahead of print] No abstract available.


Prognostic hallmarks in AML.

Clarke MA, Fisher J.

Nat Biomed Eng. 2019 Nov;3(11):847-849. doi: 10.1038/s41551-019-0474-4. No abstract available.


Recurrent heterozygous PAX6 missense variants cause severe bilateral microphthalmia via predictable effects on DNA-protein interaction.

Williamson KA, Hall HN, Owen LJ, Livesey BJ, Hanson IM, Adams GGW, Bodek S, Calvas P, Castle B, Clarke M, Deng AT, Edery P, Fisher R, Gillessen-Kaesbach G, Heon E, Hurst J, Josifova D, Lorenz B, McKee S, Meire F, Moore AT, Parker M, Reiff CM, Self J, Tobias ES, Verheij JBGM, Willems M, Williams D, van Heyningen V, Marsh JA, FitzPatrick DR.

Genet Med. 2020 Mar;22(3):598-609. doi: 10.1038/s41436-019-0685-9. Epub 2019 Nov 8.


Characterizing the Randot Preschool stereotest: Testability, norms, reliability, specificity and sensitivity in children aged 2-11 years.

Read JCA, Rafiq S, Hugill J, Casanova T, Black C, O'Neill A, Puyat V, Haggerty H, Smart K, Powell C, Taylor K, Clarke MP, Vancleef K.

PLoS One. 2019 Nov 7;14(11):e0224402. doi: 10.1371/journal.pone.0224402. eCollection 2019.

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