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Items: 1 to 50 of 1144

1.

Clarifying the Risk of Lung Disease in SZ α1-antitrypsin Deficiency.

Franciosi AN, Hobbs BD, McElvaney OJ, Molloy K, Hersh C, Clarke L, Gunaratnam C, Silverman EK, Carroll TP, McElvaney NG.

Am J Respir Crit Care Med. 2020 Mar 20. doi: 10.1164/rccm.202002-0262OC. [Epub ahead of print]

PMID:
32197047
2.

Variant calling on the GRCh38 assembly with the data from phase three of the 1000 Genomes Project.

Lowy-Gallego E, Fairley S, Zheng-Bradley X, Ruffier M, Clarke L, Flicek P; 1000 Genomes Project Consortium.

Version 2. Wellcome Open Res. 2019 Dec 30 [revised 2019 Jan 1];4:50. doi: 10.12688/wellcomeopenres.15126.2. eCollection 2019.

3.

Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy.

Ovadia C, Perdones-Montero A, Fan HM, Mullish BH, McDonald JAK, Papacleovoulou G, Wahlström A, Ståhlman M, Tsakmaki A, Clarke LCD, Sklavounos A, Dixon PH, Bewick GA, Walters JRF, Marschall HU, Marchesi JR, Williamson C.

Sci Rep. 2020 Mar 3;10(1):3895. doi: 10.1038/s41598-020-60821-w.

4.

Forecasting the prevalence of overweight and obesity in India to 2040.

Luhar S, Timæus IM, Jones R, Cunningham S, Patel SA, Kinra S, Clarke L, Houben R.

PLoS One. 2020 Feb 24;15(2):e0229438. doi: 10.1371/journal.pone.0229438. eCollection 2020.

5.

Developing synthetic biology for industrial biotechnology applications.

Clarke L, Kitney R.

Biochem Soc Trans. 2020 Feb 28;48(1):113-122. doi: 10.1042/BST20190349.

6.

Towards a European health research and innovation cloud (HRIC).

Aarestrup FM, Albeyatti A, Armitage WJ, Auffray C, Augello L, Balling R, Benhabiles N, Bertolini G, Bjaalie JG, Black M, Blomberg N, Bogaert P, Bubak M, Claerhout B, Clarke L, De Meulder B, D'Errico G, Di Meglio A, Forgo N, Gans-Combe C, Gray AE, Gut I, Gyllenberg A, Hemmrich-Stanisak G, Hjorth L, Ioannidis Y, Jarmalaite S, Kel A, Kherif F, Korbel JO, Larue C, Laszlo M, Maas A, Magalhaes L, Manneh-Vangramberen I, Morley-Fletcher E, Ohmann C, Oksvold P, Oxtoby NP, Perseil I, Pezoulas V, Riess O, Riper H, Roca J, Rosenstiel P, Sabatier P, Sanz F, Tayeb M, Thomassen G, Van Bussel J, Van den Bulcke M, Van Oyen H.

Genome Med. 2020 Feb 19;12(1):18. doi: 10.1186/s13073-020-0713-z.

7.

Machine learning for syndromic surveillance using veterinary necropsy reports.

Bollig N, Clarke L, Elsmo E, Craven M.

PLoS One. 2020 Feb 5;15(2):e0228105. doi: 10.1371/journal.pone.0228105. eCollection 2020.

8.

The clinical profile of NMOSD in Australia and New Zealand.

Bukhari W, Clarke L, O'Gorman C, Khalilidehkordi E, Arnett S, Prain KM, Woodhall M, Silvestrini R, Bundell CS, Ramanathan S, Abernethy D, Bhuta S, Blum S, Boggild M, Boundy K, Brew BJ, Brownlee W, Butzkueven H, Carroll WM, Chen C, Coulthard A, Dale RC, Das C, Dear K, Fabis-Pedrini MJ, Fulcher D, Gillis D, Hawke S, Heard R, Henderson APD, Heshmat S, Hodgkinson S, Jimenez-Sanchez S, Kilpatrick TJ, King J, Kneebone C, Kornberg AJ, Lechner-Scott J, Lin MW, Lynch C, Macdonnell RAL, Mason DF, McCombe PA, Pereira J, Pollard JD, Reddel SW, Shaw C, Spies J, Stankovich J, Sutton I, Vucic S, Walsh M, Wong RC, Yiu EM, Barnett MH, Kermode AG, Marriott MP, Parratt J, Slee M, Taylor BV, Willoughby E, Wilson RJ, Brilot F, Vincent A, Waters P, Broadley SA.

J Neurol. 2020 Jan 31. doi: 10.1007/s00415-020-09716-4. [Epub ahead of print]

PMID:
32006158
9.

Vismodegib for periocular basal cell carcinoma: an international multicentre case series.

Oliphant H, Laybourne J, Chan K, Haridas A, Edmunds MR, Morris D, Clarke L, Althaus M, Norris P, Cranstoun M, Sullivan TJ, Rajak SN.

Eye (Lond). 2020 Jan 29. doi: 10.1038/s41433-020-0778-3. [Epub ahead of print]

PMID:
31996838
10.

Mobile element insertion detection in 89,874 clinical exomes.

Torene RI, Galens K, Liu S, Arvai K, Borroto C, Scuffins J, Zhang Z, Friedman B, Sroka H, Heeley J, Beaver E, Clarke L, Neil S, Walia J, Hull D, Juusola J, Retterer K.

Genet Med. 2020 Jan 22. doi: 10.1038/s41436-020-0749-x. [Epub ahead of print]

PMID:
31965078
11.

A Review of the Role of Carcinoembryonic Antigen in Clinical Practice.

Hall C, Clarke L, Pal A, Buchwald P, Eglinton T, Wakeman C, Frizelle F.

Ann Coloproctol. 2019 Dec;35(6):294-305. doi: 10.3393/ac.2019.11.13. Epub 2019 Dec 31. Review.

12.

Access to intraoperative tumour margin control: a survey of the British Oculoplastic Surgery Society.

Oliphant H, Oliphant T, Clarke L, Vize C, Rajak S.

Eye (Lond). 2020 Jan 2. doi: 10.1038/s41433-019-0760-0. [Epub ahead of print]

PMID:
31896806
13.

How Collaborative Mentoring Networks Are Building Capacity in Primary Care.

Radhakrishnan A, Clarke L, Greenberg L.

Healthc Q. 2019 Oct;22(3):54-60. doi: 10.12927/hcq.2019.26016.

PMID:
31845859
14.

Offering Patients a Medical Home - Not a Hallway - and a Stronger Health System.

Clarke L, Mehta K.

Healthc Q. 2019 Oct;22(3):47-53. doi: 10.12927/hcq.2019.26017.

PMID:
31845858
15.

Nanoparticle-based photothermal heating to drive chemical reactions within a solid: using inhomogeneous polymer degradation to manipulate mechanical properties and segregate carbonaceous by-products.

Huang H, Firestone G, Fontecha D, Gorga RE, Bochinski JR, Clarke LI.

Nanoscale. 2020 Jan 2;12(2):904-923. doi: 10.1039/c9nr07401e.

PMID:
31833521
16.

Investigating Electrode Flooding in a Flowing Electrolyte, Gas-Fed Carbon Dioxide Electrolyzer.

Leonard ME, Clarke LE, Forner-Cuenca A, Brown SM, Brushett FR.

ChemSusChem. 2020 Jan 19;13(2):400-411. doi: 10.1002/cssc.201902547. Epub 2019 Dec 17.

PMID:
31736202
17.

TMEM16A chloride channel does not drive mucus production.

Simões FB, Quaresma MC, Clarke LA, Silva IA, Pankonien I, Railean V, Kmit A, Amaral MD.

Life Sci Alliance. 2019 Nov 15;2(6). pii: e201900462. doi: 10.26508/lsa.201900462. Print 2019 Dec.

18.

Growth patterns for untreated individuals with MPS I: Report from the international MPS I registry.

Viskochil D, Clarke LA, Bay L, Keenan H, Muenzer J, Guffon N.

Am J Med Genet A. 2019 Dec;179(12):2425-2432. doi: 10.1002/ajmg.a.61378. Epub 2019 Oct 22.

19.

Experiences and satisfaction of children, young people and their parents with alternative mental health models to inpatient settings: a systematic review.

Vusio F, Thompson A, Birchwood M, Clarke L.

Eur Child Adolesc Psychiatry. 2019 Oct 21. doi: 10.1007/s00787-019-01420-7. [Epub ahead of print] Review.

PMID:
31637520
20.

A new scenario logic for the Paris Agreement long-term temperature goal.

Rogelj J, Huppmann D, Krey V, Riahi K, Clarke L, Gidden M, Nicholls Z, Meinshausen M.

Nature. 2019 Sep;573(7774):357-363. doi: 10.1038/s41586-019-1541-4. Epub 2019 Sep 18.

21.

Genetic abnormalities in a large cohort of Coffin-Siris syndrome patients.

Sekiguchi F, Tsurusaki Y, Okamoto N, Teik KW, Mizuno S, Suzumura H, Isidor B, Ong WP, Haniffa M, White SM, Matsuo M, Saito K, Phadke S, Kosho T, Yap P, Goyal M, Clarke LA, Sachdev R, McGillivray G, Leventer RJ, Patel C, Yamagata T, Osaka H, Hisaeda Y, Ohashi H, Shimizu K, Nagasaki K, Hamada J, Dateki S, Sato T, Chinen Y, Awaya T, Kato T, Iwanaga K, Kawai M, Matsuoka T, Shimoji Y, Tan TY, Kapoor S, Gregersen N, Rossi M, Marie-Laure M, McGregor L, Oishi K, Mehta L, Gillies G, Lockhart PJ, Pope K, Shukla A, Girisha KM, Abdel-Salam GMH, Mowat D, Coman D, Kim OH, Cordier MP, Gibson K, Milunsky J, Liebelt J, Cox H, El Chehadeh S, Toutain A, Saida K, Aoi H, Minase G, Tsuchida N, Iwama K, Uchiyama Y, Suzuki T, Hamanaka K, Azuma Y, Fujita A, Imagawa E, Koshimizu E, Takata A, Mitsuhashi S, Miyatake S, Mizuguchi T, Miyake N, Matsumoto N.

J Hum Genet. 2019 Dec;64(12):1173-1186. doi: 10.1038/s10038-019-0667-4. Epub 2019 Sep 17.

PMID:
31530938
22.

Experience of and barriers to reporting child safeguarding concerns among general dental practitioners across Greater Manchester.

Clarke L, Chana P, Nazzal H, Barry S.

Br Dent J. 2019 Sep;227(5):387-391. doi: 10.1038/s41415-019-0663-2.

PMID:
31520042
23.

Photothermally-driven thermo-oxidative degradation of low density polyethylene: heterogeneous heating plus a complex reaction leads to homogeneous chemistry.

Firestone G, Huang H, Bochinski JR, Clarke LI.

Nanotechnology. 2019 Nov 22;30(47):475706. doi: 10.1088/1361-6528/ab3bc0. Epub 2019 Aug 15.

PMID:
31416060
24.

A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice.

Gawenis LR, Hodges CA, McHugh DR, Valerio DM, Miron A, Cotton CU, Liu J, Walker NM, Strubberg AM, Gillen AE, Mutolo MJ, Kotzamanis G, Bosch J, Harris A, Drumm ML, Clarke LL.

Sci Rep. 2019 Aug 14;9(1):11828. doi: 10.1038/s41598-019-48105-4.

25.

An evaluation of sequencing coverage and genotyping strategies to assess neutral and adaptive diversity.

Benjelloun B, Boyer F, Streeter I, Zamani W, Engelen S, Alberti A, Alberto FJ, BenBati M, Ibnelbachyr M, Chentouf M, Bechchari A, Rezaei HR, Naderi S, Stella A, Chikhi A, Clarke L, Kijas J, Flicek P, Taberlet P, Pompanon F.

Mol Ecol Resour. 2019 Nov;19(6):1497-1515. doi: 10.1111/1755-0998.13070. Epub 2019 Sep 9.

PMID:
31359622
26.

Dissecting Cardiac Surgery: A Video-Based Recall Protocol to Elucidate Team Cognitive Processes in the Operating Room.

Dias RD, Zenati MA, Conboy HM, Clarke LA, Osterweil LJ, Avrunin GS, Yule SJ.

Ann Surg. 2019 Jul 24. doi: 10.1097/SLA.0000000000003489. [Epub ahead of print]

PMID:
31348036
27.

Pancreatic Cancer Cachexia: The Role of Nutritional Interventions.

Mitchell T, Clarke L, Goldberg A, Bishop KS.

Healthcare (Basel). 2019 Jul 9;7(3). pii: E89. doi: 10.3390/healthcare7030089. Review.

28.

Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection: A real-world perspective and review of the literature.

Babiker A, Clarke L, Doi Y, Shields RK.

Diagn Microbiol Infect Dis. 2019 Nov;95(3):114856. doi: 10.1016/j.diagmicrobio.2019.06.008. Epub 2019 Jun 24. Review.

PMID:
31307867
29.

Health economic evaluation in orthotics and prosthetics: a systematic review protocol.

Clarke L, Dillon M, Shiell A.

Syst Rev. 2019 Jun 27;8(1):152. doi: 10.1186/s13643-019-1066-9.

30.

Do trends in the prevalence of overweight by socio-economic position differ between India's most and least economically developed states?

Luhar S, Mallinson PAC, Clarke L, Kinra S.

BMC Public Health. 2019 Jun 20;19(1):783. doi: 10.1186/s12889-019-7155-9.

31.

Genotype-phenotype relationships in mucopolysaccharidosis type I (MPS I): Insights from the International MPS I Registry.

Clarke LA, Giugliani R, Guffon N, Jones SA, Keenan HA, Munoz-Rojas MV, Okuyama T, Viskochil D, Whitley CB, Wijburg FA, Muenzer J.

Clin Genet. 2019 Oct;96(4):281-289. doi: 10.1111/cge.13583. Epub 2019 Jul 2.

32.

Central nervous system diseases of cattle in Georgia, 2001-2017.

Clarke LL, Hawkins IK, Rissi DR.

J Vet Diagn Invest. 2019 Jul;31(4):588-593. doi: 10.1177/1040638719854788. Epub 2019 Jun 10.

PMID:
31179896
33.

RAPIDOMICS: rapid genome-wide sequencing in a neonatal intensive care unit-successes and challenges.

Elliott AM, du Souich C, Lehman A, Guella I, Evans DM, Candido T, Tooman L, Armstrong L, Clarke L, Gibson W, Gill H, Lavoie PM, Lewis S, McKinnon ML, Nikkel SM, Patel M, Solimano A, Synnes A, Ting J, van Allen M, Christilaw J, Farrer MJ, Friedman JM, Osiovich H.

Eur J Pediatr. 2019 Aug;178(8):1207-1218. doi: 10.1007/s00431-019-03399-4. Epub 2019 Jun 7.

PMID:
31172278
34.

The LAPLAP study: a randomized placebo-controlled clinical trial assessing postoperative functional recovery using intraperitoneal local anaesthetic in laparoscopic colorectal surgery.

Stephensen BD, Clarke L, McManus B, Clark S, Carroll R, Holz P, Smith SR.

Colorectal Dis. 2019 Oct;21(10):1183-1191. doi: 10.1111/codi.14720. Epub 2019 Jul 2.

PMID:
31120614
35.

Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.

Cheung WA, Shao X, Morin A, Siroux V, Kwan T, Ge B, Aïssi D, Chen L, Vasquez L, Allum F, Guénard F, Bouzigon E, Simon MM, Boulier E, Redensek A, Watt S, Datta A, Clarke L, Flicek P, Mead D, Paul DS, Beck S, Bourque G, Lathrop M, Tchernof A, Vohl MC, Demenais F, Pin I, Downes K, Stunnenberg HG, Soranzo N, Pastinen T, Grundberg E.

Genome Biol. 2019 May 7;20(1):89. doi: 10.1186/s13059-019-1702-7.

36.

Multi-platform discovery of haplotype-resolved structural variation in human genomes.

Chaisson MJP, Sanders AD, Zhao X, Malhotra A, Porubsky D, Rausch T, Gardner EJ, Rodriguez OL, Guo L, Collins RL, Fan X, Wen J, Handsaker RE, Fairley S, Kronenberg ZN, Kong X, Hormozdiari F, Lee D, Wenger AM, Hastie AR, Antaki D, Anantharaman T, Audano PA, Brand H, Cantsilieris S, Cao H, Cerveira E, Chen C, Chen X, Chin CS, Chong Z, Chuang NT, Lambert CC, Church DM, Clarke L, Farrell A, Flores J, Galeev T, Gorkin DU, Gujral M, Guryev V, Heaton WH, Korlach J, Kumar S, Kwon JY, Lam ET, Lee JE, Lee J, Lee WP, Lee SP, Li S, Marks P, Viaud-Martinez K, Meiers S, Munson KM, Navarro FCP, Nelson BJ, Nodzak C, Noor A, Kyriazopoulou-Panagiotopoulou S, Pang AWC, Qiu Y, Rosanio G, Ryan M, Stütz A, Spierings DCJ, Ward A, Welch AE, Xiao M, Xu W, Zhang C, Zhu Q, Zheng-Bradley X, Lowy E, Yakneen S, McCarroll S, Jun G, Ding L, Koh CL, Ren B, Flicek P, Chen K, Gerstein MB, Kwok PY, Lansdorp PM, Marth GT, Sebat J, Shi X, Bashir A, Ye K, Devine SE, Talkowski ME, Mills RE, Marschall T, Korbel JO, Eichler EE, Lee C.

Nat Commun. 2019 Apr 16;10(1):1784. doi: 10.1038/s41467-018-08148-z.

37.

The Paris pledges and the energy-water-land nexus in Latin America: Exploring implications of greenhouse gas emission reductions.

Santos Da Silva SR, Miralles-Wilhelm F, Muñoz-Castillo R, Clarke LE, Braun CJ, Delgado A, Edmonds JA, Hejazi M, Horing J, Horowitz R, Kyle P, Link R, Patel P, Turner S, McJeon HC.

PLoS One. 2019 Apr 16;14(4):e0215013. doi: 10.1371/journal.pone.0215013. eCollection 2019.

38.

Potentially important miRNAs in enteropathy-associated T-cell lymphoma pathogenesis: A pilot study.

Clarke L, Adduri RS, Smyth P, Quinn F, Jeffers M, Dunne B, O'Leary J, McKiernan S, Vandenberghe E, Pyne S, Bashyam MD, Sheils O, Flavin R.

Leuk Res Rep. 2018 Oct 16;10:52-54. doi: 10.1016/j.lrr.2018.10.002. eCollection 2018. No abstract available.

39.

Low-dose agalsidase beta treatment in male pediatric patients with Fabry disease: A 5-year randomized controlled trial.

Ramaswami U, Bichet DG, Clarke LA, Dostalova G, Fainboim A, Fellgiebel A, Forcelini CM, An Haack K, Hopkin RJ, Mauer M, Najafian B, Scott CR, Shankar SP, Thurberg BL, Tøndel C, Tylki-Szymanska A, Bénichou B, Wijburg FA.

Mol Genet Metab. 2019 May;127(1):86-94. doi: 10.1016/j.ymgme.2019.03.010. Epub 2019 Apr 3.

40.

Pathology in Practice.

Mumaw JL, Clarke L, Butt SL, Uhl E.

J Am Vet Med Assoc. 2019 May 1;254(9):1057-1059. doi: 10.2460/javma.254.9.1057. No abstract available.

PMID:
30986151
41.

Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis.

Ovadia C, Perdones-Montero A, Spagou K, Smith A, Sarafian MH, Gomez-Romero M, Bellafante E, Clarke LCD, Sadiq F, Nikolova V, Mitchell A, Dixon PH, Santa-Pinter N, Wahlström A, Abu-Hayyeh S, Walters JRF, Marschall HU, Holmes E, Marchesi JR, Williamson C.

Hepatology. 2019 Jul;70(1):276-293. doi: 10.1002/hep.30661. Epub 2019 May 21. Erratum in: Hepatology. 2019 Dec;70(6):2243.

42.

Pulmonary vasculitis mimicking chronic thromboembolic disease.

Ali N, Clarke L, MacKenzie Ross RV, Robinson G.

BMJ Case Rep. 2019 Apr 8;12(4). pii: e228409. doi: 10.1136/bcr-2018-228409.

PMID:
30967450
43.

Investing in health R&D: where we are, what limits us, and how to make progress in Africa.

Simpkin V, Namubiru-Mwaura E, Clarke L, Mossialos E.

BMJ Glob Health. 2019 Mar 4;4(2):e001047. doi: 10.1136/bmjgh-2018-001047. eCollection 2019.

44.

Process-Model-Driven Guidance to Reduce Surgical Procedure Errors: An Expert Opinion.

Osterweil LJ, Conboy HM, Clarke LA, Avrunin GS.

Semin Thorac Cardiovasc Surg. 2019 Autumn;31(3):453-457. doi: 10.1053/j.semtcvs.2019.02.030. Epub 2019 Mar 6.

PMID:
30851373
45.

Process Driven Guidance for Complex Surgical Procedures.

Avrunin GS, Christov SC, Clarke LA, Conboy HM, Osterweil LJ, Zenati MA.

AMIA Annu Symp Proc. 2018 Dec 5;2018:175-184. eCollection 2018.

46.
47.

Antarctic Krill Are Reservoirs for Distinct Southern Ocean Microbial Communities.

Clarke LJ, Suter L, King R, Bissett A, Deagle BE.

Front Microbiol. 2019 Jan 15;9:3226. doi: 10.3389/fmicb.2018.03226. eCollection 2018.

48.

Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes.

Yi G, Wierenga ATJ, Petraglia F, Narang P, Janssen-Megens EM, Mandoli A, Merkel A, Berentsen K, Kim B, Matarese F, Singh AA, Habibi E, Prange KHM, Mulder AB, Jansen JH, Clarke L, Heath S, van der Reijden BA, Flicek P, Yaspo ML, Gut I, Bock C, Schuringa JJ, Altucci L, Vellenga E, Stunnenberg HG, Martens JHA.

Cell Rep. 2019 Jan 22;26(4):1059-1069.e6. doi: 10.1016/j.celrep.2018.12.098.

49.

Reply to Reimann et al.

Clarke LE, Leachman SA.

Mod Pathol. 2019 May;32(5):725-727. doi: 10.1038/s41379-018-0197-1. Epub 2019 Jan 21. No abstract available.

50.

Prevalence and correlates of 'sexual competence' at first heterosexual intercourse among young people in Britain.

Palmer MJ, Clarke L, Ploubidis GB, Wellings K.

BMJ Sex Reprod Health. 2019 Jan 14. pii: bmjsrh-2018-200160. doi: 10.1136/bmjsrh-2018-200160. [Epub ahead of print]

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