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Items: 1 to 50 of 224

1.

Late Cognitive Consequences of Gestational Diabetes to the Offspring, in a New Mouse Model.

de Sousa RAL, de Lima EV, da Silva TP, de Souza RV, Figueiredo CP, Passos GF, Clarke JR.

Mol Neurobiol. 2019 May 21. doi: 10.1007/s12035-019-1624-0. [Epub ahead of print]

PMID:
31115777
2.

Late Neurological Consequences of Zika Virus Infection: Risk Factors and Pharmaceutical Approaches.

Souza INO, Barros-Aragão FGQ, Frost PS, Figueiredo CP, Clarke JR.

Pharmaceuticals (Basel). 2019 Apr 17;12(2). pii: E60. doi: 10.3390/ph12020060. Review.

3.

Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice.

Frost PS, Barros-Aragão F, da Silva RT, Venancio A, Matias I, Lyra E Silva NM, Kincheski GC, Pimentel-Coelho PM, De Felice FG, Gomes FCA, Ferreira ST, Figueiredo CP, Clarke JR.

Cell Death Dis. 2019 Apr 11;10(4):323. doi: 10.1038/s41419-019-1529-x.

4.

Combined oral contraceptive in female mice causes hyperinsulinemia due to β-cell hypersecretion and reduction in insulin clearance.

Oliveira CAR, Dos Reis Araujo T, Aguiar GS, da Silva Junior JA, Vettorazzi JF, Freitas IN, Oliveira KM, Boschero AC, Bonfleur ML, Clarke JR, Henriques HN, Ribeiro RA.

J Steroid Biochem Mol Biol. 2019 Jun;190:54-63. doi: 10.1016/j.jsbmb.2019.03.018. Epub 2019 Mar 25.

PMID:
30923014
5.

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.

Lourenco MV, Frozza RL, de Freitas GB, Zhang H, Kincheski GC, Ribeiro FC, Gonçalves RA, Clarke JR, Beckman D, Staniszewski A, Berman H, Guerra LA, Forny-Germano L, Meier S, Wilcock DM, de Souza JM, Alves-Leon S, Prado VF, Prado MAM, Abisambra JF, Tovar-Moll F, Mattos P, Arancio O, Ferreira ST, De Felice FG.

Nat Med. 2019 Jan;25(1):165-175. doi: 10.1038/s41591-018-0275-4. Epub 2019 Jan 7.

6.

High blood lead concentrations in captive Tasmanian devils (Sarcophilus harrisii): a threat to the conservation of the species?

Hivert LG, Clarke JR, Peck SJ, Lawrence C, Brown WE, Huxtable SJ, Schaap D, Pemberton D, Grueber CE.

Aust Vet J. 2018 Nov;96(11):442-449. doi: 10.1111/avj.12753.

PMID:
30370598
7.

Patient-specific predictors of failure to rescue after pancreaticoduodenectomy.

Gleeson EM, Clarke JR, Morano WF, Shaikh MF, Bowne WB, Pitt HA.

HPB (Oxford). 2019 Mar;21(3):283-290. doi: 10.1016/j.hpb.2018.07.022. Epub 2018 Aug 22.

PMID:
30143319
8.

Acute and chronic neurological consequences of early-life Zika virus infection in mice.

Nem de Oliveira Souza I, Frost PS, França JV, Nascimento-Viana JB, Neris RLS, Freitas L, Pinheiro DJLL, Nogueira CO, Neves G, Chimelli L, De Felice FG, Cavalheiro ÉA, Ferreira ST, Assunção-Miranda I, Figueiredo CP, Da Poian AT, Clarke JR.

Sci Transl Med. 2018 Jun 6;10(444). pii: eaar2749. doi: 10.1126/scitranslmed.aar2749.

PMID:
29875203
9.

Re: Evaluation of regulator performance in polar diving - authors' response.

Lang MA, Clarke JR.

Undersea Hyperb Med. 2018 Jan-Feb;45(1):112-114. No abstract available.

PMID:
29571241
10.

Metabolic Dysfunction in Alzheimer's Disease: From Basic Neurobiology to Clinical Approaches.

Clarke JR, Ribeiro FC, Frozza RL, De Felice FG, Lourenco MV.

J Alzheimers Dis. 2018;64(s1):S405-S426. doi: 10.3233/JAD-179911. Review.

PMID:
29562518
11.

The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease.

Batista AF, Forny-Germano L, Clarke JR, Lyra E Silva NM, Brito-Moreira J, Boehnke SE, Winterborn A, Coe BC, Lablans A, Vital JF, Marques SA, Martinez AM, Gralle M, Holscher C, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG.

J Pathol. 2018 May;245(1):85-100. doi: 10.1002/path.5056. Epub 2018 Apr 2.

12.

Consequences of gestational diabetes to the brain and behavior of the offspring.

Sousa RAL, Torres YS, Figueiredo CP, Passos GF, Clarke JR.

An Acad Bras Cienc. 2018 Aug;90(2 suppl 1):2279-2291. doi: 10.1590/0001-3765201720170264. Epub 2017 Aug 14.

13.

Performance of life support breathing apparatus for under-ice diving operations.

Lang MA, Clarke JR.

Undersea Hyperb Med. 2017 Jul-Aug;44(4):299-308.

PMID:
28783885
14.

Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson's disease-like symptoms in mice.

Fortuna JTS, Gralle M, Beckman D, Neves FS, Diniz LP, Frost PS, Barros-Aragão F, Santos LE, Gonçalves RA, Romão L, Zamberlan DC, Soares FAA, Braga C, Foguel D, Gomes FCA, De Felice FG, Ferreira ST, Clarke JR, Figueiredo CP.

Behav Brain Res. 2017 Aug 30;333:150-160. doi: 10.1016/j.bbr.2017.06.047. Epub 2017 Jun 29.

PMID:
28668282
15.

Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice.

Kincheski GC, Valentim IS, Clarke JR, Cozachenco D, Castelo-Branco MTL, Ramos-Lobo AM, Rumjanek VMBD, Donato J Jr, De Felice FG, Ferreira ST.

Brain Behav Immun. 2017 Aug;64:140-151. doi: 10.1016/j.bbi.2017.04.007. Epub 2017 Apr 13.

PMID:
28412140
16.

Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice.

Brito-Moreira J, Lourenco MV, Oliveira MM, Ribeiro FC, Ledo JH, Diniz LP, Vital JFS, Magdesian MH, Melo HM, Barros-Aragão F, de Souza JM, Alves-Leon SV, Gomes FCA, Clarke JR, Figueiredo CP, De Felice FG, Ferreira ST.

J Biol Chem. 2017 May 5;292(18):7327-7337. doi: 10.1074/jbc.M116.761189. Epub 2017 Mar 10.

17.

Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice.

Neves FS, Marques PT, Barros-Aragão F, Nunes JB, Venancio AM, Cozachenco D, Frozza RL, Passos GF, Costa R, de Oliveira J, Engel DF, De Bem AF, Benjamim CF, De Felice FG, Ferreira ST, Clarke JR, Figueiredo CP.

Mol Neurobiol. 2018 Jan;55(1):435-444. doi: 10.1007/s12035-016-0307-3. Epub 2016 Dec 13.

PMID:
27966074
18.

WHipple-ABACUS, a simple, validated risk score for 30-day mortality after pancreaticoduodenectomy developed using the ACS-NSQIP database.

Gleeson EM, Shaikh MF, Shewokis PA, Clarke JR, Meyers WC, Pitt HA, Bowne WB.

Surgery. 2016 Nov;160(5):1279-1287. doi: 10.1016/j.surg.2016.06.040. Epub 2016 Aug 17.

PMID:
27544541
19.

NICE clinical guideline: bronchiolitis in children.

Caffrey Osvald E, Clarke JR.

Arch Dis Child Educ Pract Ed. 2016 Feb;101(1):46-8. doi: 10.1136/archdischild-2015-309156. Epub 2015 Dec 1. No abstract available.

PMID:
26628507
20.

Temporal and Regional Expression of Glucose-Dependent Insulinotropic Peptide and Its Receptor in Spinal Cord Injured Rats.

Marcos AB, Forner S, Martini AC, Patrício ES, Clarke JR, Costa R, Felix-Alves J, Vieira VJ, de Andrade EL, Mazzuco TL, Calixto JB, Figueiredo CP.

J Neurotrauma. 2016 Feb 1;33(3):261-8. doi: 10.1089/neu.2015.3877. Epub 2015 Dec 23.

21.

Wrong surgery: why does not the Universal Protocol solve the problem?

Clarke JR.

Am J Surg. 2015 Jul;210(1):14. doi: 10.1016/j.amjsurg.2015.05.001. Epub 2015 May 21. No abstract available.

PMID:
26033360
22.

Don't dive cold when you don't have to.

Clarke JR, Moon RE, Chimiak JM, Stinton R, Van Hoesen KB, Lang MA.

Diving Hyperb Med. 2015 Mar;45(1):62. No abstract available.

PMID:
25964043
23.

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

Clarke JR, Lyra E Silva NM, Figueiredo CP, Frozza RL, Ledo JH, Beckman D, Katashima CK, Razolli D, Carvalho BM, Frazão R, Silveira MA, Ribeiro FC, Bomfim TR, Neves FS, Klein WL, Medeiros R, LaFerla FM, Carvalheira JB, Saad MJ, Munoz DP, Velloso LA, Ferreira ST, De Felice FG.

EMBO Mol Med. 2015 Feb;7(2):190-210. doi: 10.15252/emmm.201404183.

24.

The use of collaboration to implement evidence-based safe practices.

Clarke JR.

J Public Health Res. 2013 Dec 1;2(3):e26. doi: 10.4081/jphr.2013.e26. eCollection 2013 Dec 1. Review.

25.

Is your office helping you prevent wrong site surgery?

Clarke JR.

Bull Am Coll Surg. 2014 Apr;99(4):28-31. No abstract available.

PMID:
24783704
26.

Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease.

Ferreira ST, Clarke JR, Bomfim TR, De Felice FG.

Alzheimers Dement. 2014 Feb;10(1 Suppl):S76-83. doi: 10.1016/j.jalz.2013.12.010. Review.

27.

TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

Lourenco MV, Clarke JR, Frozza RL, Bomfim TR, Forny-Germano L, Batista AF, Sathler LB, Brito-Moreira J, Amaral OB, Silva CA, Freitas-Correa L, Espírito-Santo S, Campello-Costa P, Houzel JC, Klein WL, Holscher C, Carvalheira JB, Silva AM, Velloso LA, Munoz DP, Ferreira ST, De Felice FG.

Cell Metab. 2013 Dec 3;18(6):831-43. doi: 10.1016/j.cmet.2013.11.002.

28.

Giant left atrial appendage aneurysm in a neonate.

Clarke JR, Zvaigzne CG, Disler D, Giuffre RM, Rebeyka IM, Patton DJ.

World J Pediatr Congenit Heart Surg. 2012 Jul 1;3(3):392-5. doi: 10.1177/2150135112437251.

PMID:
23804878
29.

Memantine rescues transient cognitive impairment caused by high-molecular-weight aβ oligomers but not the persistent impairment induced by low-molecular-weight oligomers.

Figueiredo CP, Clarke JR, Ledo JH, Ribeiro FC, Costa CV, Melo HM, Mota-Sales AP, Saraiva LM, Klein WL, Sebollela A, De Felice FG, Ferreira ST.

J Neurosci. 2013 Jun 5;33(23):9626-34. doi: 10.1523/JNEUROSCI.0482-13.2013.

30.

Oral sodium thiosulfate as maintenance therapy for calcific uremic arteriolopathy: a case series.

AlBugami MM, Wilson JA, Clarke JR, Soroka SD.

Am J Nephrol. 2013;37(2):104-9. doi: 10.1159/000346410. Epub 2013 Jan 25.

PMID:
23363879
31.

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice.

Ledo JH, Azevedo EP, Clarke JR, Ribeiro FC, Figueiredo CP, Foguel D, De Felice FG, Ferreira ST.

Mol Psychiatry. 2013 Oct;18(10):1053-4. doi: 10.1038/mp.2012.168. Epub 2012 Nov 27. No abstract available.

32.

Procedural safety in emergency care: a conceptual model and recommendations.

Pines JM, Kelly JJ, Meisl H, Augustine JJ, Broida RI, Clarke JR, Farley H, Franklin M, Fuller DC, Klauer K, Phelan MP, Schuur JD, Stone-Griffith S, Thallner E, Wears RL.

Jt Comm J Qual Patient Saf. 2012 Nov;38(11):516-26. No abstract available.

PMID:
23173399
33.

Ethics in radiology: wait lists queue jumping.

Cunningham N, Reid L, MacSwain S, Clarke JR.

Can Assoc Radiol J. 2013 Aug;64(3):170-5. doi: 10.1016/j.carj.2011.12.006. Epub 2012 Aug 4. Review.

34.

Mapping a Large Patient Safety Database to the 2005 Patient Safety Event Taxonomy.

Clarke JR, Johnston J, Davis M, Augustine AJ, Grissinger M, Gaunt MJ, Cohen H, Marella W.

In: Henriksen K, Battles JB, Keyes MA, Grady ML, editors. Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 1: Assessment). Rockville (MD): Agency for Healthcare Research and Quality; 2008 Aug.

35.

Establishing a global learning community for incident-reporting systems.

Pham JC, Gianci S, Battles J, Beard P, Clarke JR, Coates H, Donaldson L, Eldridge N, Fletcher M, Goeschel CA, Heitmiller E, Hensen J, Kelley E, Loeb J, Runciman W, Sheridan S, Wu AW, Pronovost PJ.

Qual Saf Health Care. 2010 Oct;19(5):446-51. doi: 10.1136/qshc.2009.037739.

PMID:
20977995
36.

Plastic modifications induced by object recognition memory processing.

Clarke JR, Cammarota M, Gruart A, Izquierdo I, Delgado-García JM.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2652-7. doi: 10.1073/pnas.0915059107. Epub 2010 Jan 25.

37.

Wrong site surgery near misses and actual occurrences.

Blanco M, Clarke JR, Martindell D.

AORN J. 2009 Aug;90(2):215-8, 221-2. doi: 10.1016/j.aorn.2009.07.010.

PMID:
19664413
38.

Single-shot steady-state free precession can detect myocardial edema in patients: a feasibility study.

Green JD, Clarke JR, Flewitt JA, Friedrich MG.

J Magn Reson Imaging. 2009 Sep;30(3):690-5. doi: 10.1002/jmri.21868.

PMID:
19634173
39.

Patent ductus arteriosus demonstrated in an adult patient using cardiovascular magnetic resonance imaging.

Clarke JR, Strohm O, Patton DJ.

Can J Cardiol. 2009 Jan;25(1):e17. No abstract available.

40.

Wrong-site surgery: can we prevent it?

Clarke JR, Johnston J, Blanco M, Martindell DP.

Adv Surg. 2008;42:13-31. Review.

PMID:
18953807
41.

A comparison of methods for assessing penetrating trauma on retrospective multi-center data.

Ahmed BA, Matheny ME, Rice PL, Clarke JR, Ogunyemi OI.

J Biomed Inform. 2009 Apr;42(2):308-16. doi: 10.1016/j.jbi.2008.09.002. Epub 2008 Oct 1.

43.

The role of the entorhinal cortex in extinction: influences of aging.

Bevilaqua LR, Rossato JI, Bonini JS, Myskiw JC, Clarke JR, Monteiro S, Lima RH, Medina JH, Cammarota M, Izquierdo I.

Neural Plast. 2008;2008:595282. doi: 10.1155/2008/595282. Review.

44.

Posttraining activation of CB1 cannabinoid receptors in the CA1 region of the dorsal hippocampus impairs object recognition long-term memory.

Clarke JR, Rossato JI, Monteiro S, Bevilaqua LR, Izquierdo I, Cammarota M.

Neurobiol Learn Mem. 2008 Sep;90(2):374-81. doi: 10.1016/j.nlm.2008.04.009. Epub 2008 Jun 3.

PMID:
18524639
45.

A roadmap to safe surgical care: a view from Pennsylvania.

Clarke JR.

Bull Am Coll Surg. 2007 Nov;92(11):28-31.

PMID:
18041235
46.

Sirolimus-related pulmonary toxicity mimicking 'asthma like' symptoms.

Gupte GL, Mahadevan S, Clarke JR, Alton H, Beath SV.

World J Gastroenterol. 2007 Oct 14;13(38):5151-3.

47.

The role for leaders of health care organizations in patient safety.

Clarke JR, Lerner JC, Marella W.

Am J Med Qual. 2007 Sep-Oct;22(5):311-8.

PMID:
17804390
48.

Getting surgery right.

Clarke JR, Johnston J, Finley ED.

Ann Surg. 2007 Sep;246(3):395-403, discussion 403-5.

49.

Atypical brown fat distribution in young males demonstrated on PET/CT.

Clarke JR, Brglevska S, Lau EW, Ramdave S, Hicks RJ.

Clin Nucl Med. 2007 Sep;32(9):679-82.

PMID:
17710017
50.

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