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Items: 1 to 50 of 286

1.

A phase Ib study of the combination regorafenib with PF-03446962 in patients with refractory metastatic colorectal cancer (REGAL-1 trial).

Clarke JM, Blobe GC, Strickler JH, Uronis HE, Zafar SY, Morse M, Dropkin E, Howard L, O'Neill M, Rushing CN, Niedzwiecki D, Watson H, Bolch E, Arrowood C, Liu Y, Nixon AB, Hurwitz HI.

Cancer Chemother Pharmacol. 2019 Aug 23. doi: 10.1007/s00280-019-03916-0. [Epub ahead of print]

PMID:
31444620
2.

Fusarium Head Blight in Durum Wheat: Recent Status, Breeding Directions, and Future Research Prospects.

Haile JK, N'Diaye A, Walkowiak S, Nilsen KT, Clarke JM, Kutcher HR, Steiner B, Buerstmayr H, Pozniak CJ.

Phytopathology. 2019 Sep 3:PHYTO03190095RVW. doi: 10.1094/PHYTO-03-19-0095-RVW. [Epub ahead of print]

PMID:
31369363
3.

Therapeutic outcomes in non-small cell lung cancer with BRAF mutations: a single institution, retrospective cohort study.

Tan I, Stinchcombe TE, Ready NE, Crawford J, Datto MB, Nagy RJ, Lanman RB, Gu L, Clarke JM.

Transl Lung Cancer Res. 2019 Jun;8(3):258-267. doi: 10.21037/tlcr.2019.04.03.

4.

Guiding interoperable electronic health records through patient-sharing networks.

Clarke JM, Warren LR, Arora S, Barahona M, Darzi AW.

NPJ Digit Med. 2018 Dec 10;1:65. doi: 10.1038/s41746-018-0072-y. eCollection 2018.

5.

Pharmacokinetic characteristics of vactosertib, a new activin receptor-like kinase 5 inhibitor, in patients with advanced solid tumors in a first-in-human phase 1 study.

Jung SY, Hwang S, Clarke JM, Bauer TM, Keedy VL, Lee H, Park N, Kim SJ, Lee JI.

Invest New Drugs. 2019 Jul 13. doi: 10.1007/s10637-019-00835-y. [Epub ahead of print]

PMID:
31300967
6.

Transitions of care across hospital settings in patients with inflammatory bowel disease.

Warren LR, Clarke JM, Arora S, Barahona M, Arebi N, Darzi A.

World J Gastroenterol. 2019 May 7;25(17):2122-2132. doi: 10.3748/wjg.v25.i17.2122.

7.

Durum wheat genome highlights past domestication signatures and future improvement targets.

Maccaferri M, Harris NS, Twardziok SO, Pasam RK, Gundlach H, Spannagl M, Ormanbekova D, Lux T, Prade VM, Milner SG, Himmelbach A, Mascher M, Bagnaresi P, Faccioli P, Cozzi P, Lauria M, Lazzari B, Stella A, Manconi A, Gnocchi M, Moscatelli M, Avni R, Deek J, Biyiklioglu S, Frascaroli E, Corneti S, Salvi S, Sonnante G, Desiderio F, Marè C, Crosatti C, Mica E, Özkan H, Kilian B, De Vita P, Marone D, Joukhadar R, Mazzucotelli E, Nigro D, Gadaleta A, Chao S, Faris JD, Melo ATO, Pumphrey M, Pecchioni N, Milanesi L, Wiebe K, Ens J, MacLachlan RP, Clarke JM, Sharpe AG, Koh CS, Liang KYH, Taylor GJ, Knox R, Budak H, Mastrangelo AM, Xu SS, Stein N, Hale I, Distelfeld A, Hayden MJ, Tuberosa R, Walkowiak S, Mayer KFX, Ceriotti A, Pozniak CJ, Cattivelli L.

Nat Genet. 2019 May;51(5):885-895. doi: 10.1038/s41588-019-0381-3. Epub 2019 Apr 8.

PMID:
30962619
8.

Novel cancer therapies and their association with diabetes.

Shariff AI, Syed S, Shelby RA, Force J, Clarke JM, D'Alessio D, Corsino L.

J Mol Endocrinol. 2019 Feb 1;62(2):R187-R199. doi: 10.1530/JME-18-0002. Review.

PMID:
30532995
9.

Anatomy of the Superficial Fascia System of the Breast: A Comprehensive Theory of Breast Fascial Anatomy.

Rehnke RD, Groening RM, Van Buskirk ER, Clarke JM.

Plast Reconstr Surg. 2018 Nov;142(5):1135-1144. doi: 10.1097/PRS.0000000000004948.

10.

Haplotype Loci Under Selection in Canadian Durum Wheat Germplasm Over 60 Years of Breeding: Association With Grain Yield, Quality Traits, Protein Loss, and Plant Height.

N'Diaye A, Haile JK, Nilsen KT, Walkowiak S, Ruan Y, Singh AK, Clarke FR, Clarke JM, Pozniak CJ.

Front Plant Sci. 2018 Nov 5;9:1589. doi: 10.3389/fpls.2018.01589. eCollection 2018.

11.

High density genetic mapping of Fusarium head blight resistance QTL in tetraploid wheat.

Sari E, Berraies S, Knox RE, Singh AK, Ruan Y, Cuthbert RD, Pozniak CJ, Henriquez MA, Kumar S, Burt AJ, N'Diaye A, Konkin DJ, Cabral AL, Campbell HL, Wiebe K, Condie J, Lokuruge P, Meyer B, Fedak G, Clarke FR, Clarke JM, Somers DJ, Fobert PR.

PLoS One. 2018 Oct 11;13(10):e0204362. doi: 10.1371/journal.pone.0204362. eCollection 2018.

12.

Comparison of cancer diagnosis recording between the Clinical Practice Research Datalink, Cancer Registry and Hospital Episodes Statistics.

Arhi CS, Bottle A, Burns EM, Clarke JM, Aylin P, Ziprin P, Darzi A.

Cancer Epidemiol. 2018 Dec;57:148-157. doi: 10.1016/j.canep.2018.08.009. Epub 2018 Oct 2.

PMID:
30290998
13.

Subacute cutaneous lupus erythematosus and dermatomyositis associated with anti-programmed cell death 1 therapy.

Marano AL, Clarke JM, Morse MA, Shah A, Barrow W, Selim MA, Hall RP 3rd, Cardones AR.

Br J Dermatol. 2019 Sep;181(3):580-583. doi: 10.1111/bjd.17245. Epub 2018 Dec 10.

PMID:
30244487
14.

Genetic analysis of resistance to stripe rust in durum wheat (Triticum turgidum L. var. durum).

Lin X, N'Diaye A, Walkowiak S, Nilsen KT, Cory AT, Haile J, Kutcher HR, Ammar K, Loladze A, Huerta-Espino J, Clarke JM, Ruan Y, Knox R, Fobert P, Sharpe AG, Pozniak CJ.

PLoS One. 2018 Sep 19;13(9):e0203283. doi: 10.1371/journal.pone.0203283. eCollection 2018.

15.

Yield of Malignant Pleural Effusion for Detection of Oncogenic Driver Mutations in Lung Adenocarcinoma.

DeMaio A, Clarke JM, Dash R, Sebastian S, Wahidi MM, Shofer SL, Cheng GZ, Li X, Wang X, Mahmood K.

J Bronchology Interv Pulmonol. 2019 Apr;26(2):96-101. doi: 10.1097/LBR.0000000000000534.

PMID:
30048416
16.

The transformative role of interaction rituals within therapeutic communities.

Clarke JM, Waring J.

Sociol Health Illn. 2018 Nov;40(8):1277-1293. doi: 10.1111/1467-9566.12773. Epub 2018 Jun 29.

17.

Acute Exposure to Low-to-Moderate Carbon Dioxide Levels and Submariner Decision Making.

Rodeheffer CD, Chabal S, Clarke JM, Fothergill DM.

Aerosp Med Hum Perform. 2018 Jun 1;89(6):520-525. doi: 10.3357/AMHP.5010.2018. Erratum in: Aerosp Med Hum Perform. 2018 Jul 1;89(7):667.

PMID:
29789085
18.

Immune Checkpoint Blockade: The New Frontier in Cancer Treatment.

Clarke JM, George DJ, Lisi S, Salama AKS.

Target Oncol. 2018 Feb;13(1):1-20. doi: 10.1007/s11523-017-0549-7.

PMID:
29441437
19.

Pilot feasibility study examining a structured self-management diabetes education programme, DESMOND-ID, targeting HbA1c in adults with intellectual disabilities.

Taggart L, Truesdale M, Carey ME, Martin-Stacey L, Scott J, Bunting B, Coates V, Brown M, Karatzias T, Northway R, Clarke JM.

Diabet Med. 2018 Jan;35(1):137-146. doi: 10.1111/dme.13539. Epub 2017 Nov 21.

PMID:
29083501
20.

Leptomeningeal disease: current diagnostic and therapeutic strategies.

Nayar G, Ejikeme T, Chongsathidkiet P, Elsamadicy AA, Blackwell KL, Clarke JM, Lad SP, Fecci PE.

Oncotarget. 2017 Aug 16;8(42):73312-73328. doi: 10.18632/oncotarget.20272. eCollection 2017 Sep 22. Review.

21.

Correction: Single Marker and Haplotype-Based Association Analysis of Semolina and Pasta Colour in Elite Durum Wheat Breeding Lines Using a High-Density Consensus Map.

N'Diaye A, Haile JK, Cory AT, Clarke FR, Clarke JM, Knox RE, Pozniak CJ.

PLoS One. 2017 Oct 24;12(10):e0187178. doi: 10.1371/journal.pone.0187178. eCollection 2017.

22.

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 Oct 18;18(11):1271. doi: 10.1038/ni1117-1271c.

PMID:
29044240
23.

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 Jul 19;18(8):951. doi: 10.1038/ni0817-951c. No abstract available.

PMID:
28722715
24.

High density mapping and haplotype analysis of the major stem-solidness locus SSt1 in durum and common wheat.

Nilsen KT, N'Diaye A, MacLachlan PR, Clarke JM, Ruan Y, Cuthbert RD, Knox RE, Wiebe K, Cory AT, Walkowiak S, Beres BL, Graf RJ, Clarke FR, Sharpe AG, Distelfeld A, Pozniak CJ.

PLoS One. 2017 Apr 11;12(4):e0175285. doi: 10.1371/journal.pone.0175285. eCollection 2017.

25.

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 May;18(5):552-562. doi: 10.1038/ni.3713. Epub 2017 Mar 27. Erratum in: Nat Immunol. 2017 Jul 19;18(8):951. Erratum in: Nat Immunol. 2017 Oct 18;18(11):1271.

PMID:
28346408
26.

Prolonged sedentary time and physical fitness among Canadian men and women aged 60 to 69.

Dogra S, Clarke JM, Copeland JL.

Health Rep. 2017 Feb 15;28(2):3-9.

27.

Single Marker and Haplotype-Based Association Analysis of Semolina and Pasta Colour in Elite Durum Wheat Breeding Lines Using a High-Density Consensus Map.

N'Diaye A, Haile JK, Cory AT, Clarke FR, Clarke JM, Knox RE, Pozniak CJ.

PLoS One. 2017 Jan 30;12(1):e0170941. doi: 10.1371/journal.pone.0170941. eCollection 2017. Erratum in: PLoS One. 2017 Oct 24;12 (10 ):e0187178.

28.

Dietary butyrylated high-amylose starch reduces azoxymethane-induced colonic O(6)-methylguanine adducts in rats as measured by immunohistochemistry and high-pressure liquid chromatography.

Le Leu RK, Scherer BL, Mano MT, Winter JM, Lannagan T, Head RJ, Lockett T, Clarke JM.

Nutr Res. 2016 Sep;36(9):982-988. doi: 10.1016/j.nutres.2016.06.006. Epub 2016 Jun 7.

PMID:
27632918
29.

Stop denying migrants their fundamental right to healthcare.

Clarke JM.

BMJ. 2016 Apr 12;353:i1971. doi: 10.1136/bmj.i1971. No abstract available.

30.

Surrogate clinical endpoints to predict overall survival in non-small cell lung cancer trials-are we in a new era?

Clarke JM, Wang X, Ready NE.

Transl Lung Cancer Res. 2015 Dec;4(6):804-8. doi: 10.3978/j.issn.2218-6751.2015.05.03.

31.

Identifying Blood-Based Protein Biomarkers for Antiangiogenic Agents in the Clinic: A Decade of Progress.

Hatch AJ, Clarke JM, Nixon AB, Hurwitz HI.

Cancer J. 2015 Jul-Aug;21(4):322-6. doi: 10.1097/PPO.0000000000000129. Review.

PMID:
26222085
32.

Morphologic analysis of false negative SurePath® slides using Focalpoint™ GS computer-assisted cervical screening technology: An Australian experience.

Bowditch RC, Clarke JM, Baird PJ, Greenberg ML.

Diagn Cytopathol. 2015 Nov;43(11):870-8. doi: 10.1002/dc.23314. Epub 2015 Jul 15.

PMID:
26174002
33.

Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial.

Conlon MA, Bird AR, Clarke JM, Le Leu RK, Christophersen CT, Lockett TJ, Topping DL.

J Nutr. 2015 May;145(5):1030-1. doi: 10.3945/jn.114.209460. No abstract available.

PMID:
25934666
34.

Venous thromboembolism prophylaxis and treatment in patients with cancer: american society of clinical oncology clinical practice guideline update 2014.

Lyman GH, Bohlke K, Khorana AA, Kuderer NM, Lee AY, Arcelus JI, Balaban EP, Clarke JM, Flowers CR, Francis CW, Gates LE, Kakkar AK, Key NS, Levine MN, Liebman HA, Tempero MA, Wong SL, Somerfield MR, Falanga A; American Society of Clinical Oncology.

J Clin Oncol. 2015 Feb 20;33(6):654-6. doi: 10.1200/JCO.2014.59.7351. Epub 2015 Jan 20.

35.

Butyrylated starch affects colorectal cancer markers beneficially and dose-dependently in genotoxin-treated rats.

Toden S, Lockett TJ, Topping DL, Scherer BL, Watson EJ, Southwood JG, Clarke JM.

Cancer Biol Ther. 2014;15(11):1515-23. doi: 10.4161/15384047.2014.955764.

36.

A consensus framework map of durum wheat (Triticum durum Desf.) suitable for linkage disequilibrium analysis and genome-wide association mapping.

Maccaferri M, Cane' MA, Sanguineti MC, Salvi S, Colalongo MC, Massi A, Clarke F, Knox R, Pozniak CJ, Clarke JM, Fahima T, Dubcovsky J, Xu S, Ammar K, Karsai I, Vida G, Tuberosa R.

BMC Genomics. 2014 Oct 7;15:873. doi: 10.1186/1471-2164-15-873.

37.

Housing experimental rats in solid-based cages with digestible bedding may confound outcomes of nutritional studies.

Le Leu RK, Conlon MA, Bird AR, Clarke JM.

J Sci Food Agric. 2015 Aug 15;95(10):2155-8. doi: 10.1002/jsfa.6919. Epub 2014 Oct 18.

PMID:
25242209
38.

Dietary supplementation of propionylated starch to domestic cats provides propionic acid as gluconeogenic substrate potentially sparing the amino acid valine.

Rochus K, Cools A, Janssens GP, Vanhaecke L, Wuyts B, Lockett T, Clarke JM, Fievez V, Hesta M.

J Nutr Sci. 2014 Aug 13;3:e16. doi: 10.1017/jns.2014.18. eCollection 2014.

39.

Understanding the mechanisms of action of antiangiogenic agents in metastatic colorectal cancer: a clinician's perspective.

Clarke JM, Hurwitz HI, Rangwala F.

Cancer Treat Rev. 2014 Oct;40(9):1065-72. doi: 10.1016/j.ctrv.2014.07.001. Epub 2014 Jul 11. Review.

PMID:
25047778
40.

An infected enlarging abdominal aortic aneurysm after acute cholecystitis.

Hwang SY, Clarke JM, Tang TY.

Int J Surg Case Rep. 2014;5(5):237-9. doi: 10.1016/j.ijscr.2014.02.012. Epub 2014 Mar 12.

41.

Genetics of pre-harvest sprouting resistance in a cross of Canadian adapted durum wheat genotypes.

Singh AK, Knox RE, Clarke JM, Clarke FR, Singh A, Depauw RM, Cuthbert RD.

Mol Breed. 2014;33:919-929. Epub 2014 Jan 3.

42.

Hyponatremia: Special Considerations in Older Patients.

Soiza RL, Cumming K, Clarke JM, Wood KM, Myint PK.

J Clin Med. 2014 Aug 18;3(3):944-58. doi: 10.3390/jcm3030944. Review.

43.

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.

Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D, Nakanishi Y, Uetake C, Kato K, Kato T, Takahashi M, Fukuda NN, Murakami S, Miyauchi E, Hino S, Atarashi K, Onawa S, Fujimura Y, Lockett T, Clarke JM, Topping DL, Tomita M, Hori S, Ohara O, Morita T, Koseki H, Kikuchi J, Honda K, Hase K, Ohno H.

Nature. 2013 Dec 19;504(7480):446-50. doi: 10.1038/nature12721. Epub 2013 Nov 13. Erratum in: Nature. 2014 Feb 13;506(7487):254.

PMID:
24226770
44.

Understanding and targeting resistance to anti-angiogenic therapies.

Clarke JM, Hurwitz HI.

J Gastrointest Oncol. 2013 Sep;4(3):253-63. doi: 10.3978/j.issn.2078-6891.2013.036.

45.

Butyrylated starch increases colonic butyrate concentration but has limited effects on immunity in healthy physically active individuals.

West NP, Christophersen CT, Pyne DB, Cripps AW, Conlon MA, Topping DL, Kang S, McSweeney CS, Fricker PA, Aguirre D, Clarke JM.

Exerc Immunol Rev. 2013;19:102-19.

46.

Targeted inhibition of VEGF receptor 2: an update on ramucirumab.

Clarke JM, Hurwitz HI.

Expert Opin Biol Ther. 2013 Aug;13(8):1187-96. doi: 10.1517/14712598.2013.810717. Epub 2013 Jun 26. Review.

47.

Venous thromboembolism prophylaxis and treatment in patients with cancer: American Society of Clinical Oncology clinical practice guideline update.

Lyman GH, Khorana AA, Kuderer NM, Lee AY, Arcelus JI, Balaban EP, Clarke JM, Flowers CR, Francis CW, Gates LE, Kakkar AK, Key NS, Levine MN, Liebman HA, Tempero MA, Wong SL, Prestrud AA, Falanga A; American Society of Clinical Oncology Clinical Practice.

J Clin Oncol. 2013 Jun 10;31(17):2189-204. doi: 10.1200/JCO.2013.49.1118. Epub 2013 May 13. Review.

PMID:
23669224
48.

Identification and mapping of leaf, stem and stripe rust resistance quantitative trait loci and their interactions in durum wheat.

Singh A, Pandey MP, Singh AK, Knox RE, Ammar K, Clarke JM, Clarke FR, Singh RP, Pozniak CJ, Depauw RM, McCallum BD, Cuthbert RD, Randhawa HS, Fetch TG Jr.

Mol Breed. 2013 Feb;31(2):405-418. Epub 2012 Oct 20.

49.

Novel therapies for the treatment of advanced prostate cancer.

Clarke JM, Armstrong AJ.

Curr Treat Options Oncol. 2013 Mar;14(1):109-26. doi: 10.1007/s11864-012-0222-4. Review.

50.

Identification of novel QTL for resistance to Fusarium head blight in a tetraploid wheat population.

Ruan Y, Comeau A, Langevin F, Hucl P, Clarke JM, Brule-Babel A, Pozniak CJ.

Genome. 2012 Dec;55(12):853-64. doi: 10.1139/gen-2012-0110. Epub 2012 Nov 1.

PMID:
23231604

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