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Items: 27

1.

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.

Rajakulendran N, Rowland KJ, Selvadurai HJ, Ahmadi M, Park NI, Naumenko S, Dolma S, Ward RJ, So M, Lee L, MacLeod G, Pasiliao C, Brandon C, Clarke ID, Cusimano MD, Bernstein M, Batada N, Angers S, Dirks PB.

Genes Dev. 2019 May 1;33(9-10):498-510. doi: 10.1101/gad.321968.118. Epub 2019 Mar 6.

PMID:
30842215
2.

Estimating success of vaginal birth after caesarean section in a regional Australian population: Validation of a prediction model.

Mooney SS, Hiscock R, Clarke ID, Craig S.

Aust N Z J Obstet Gynaecol. 2019 Feb;59(1):66-70. doi: 10.1111/ajo.12809. Epub 2018 Apr 19.

PMID:
29672825
3.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB.

Cell Stem Cell. 2017 Sep 7;21(3):411. doi: 10.1016/j.stem.2017.08.008. No abstract available.

4.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB.

Cell Stem Cell. 2017 Aug 3;21(2):209-224.e7. doi: 10.1016/j.stem.2017.06.004. Epub 2017 Jul 14. Erratum in: Cell Stem Cell. 2017 Sep 7;21(3):411.

5.

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.

Dolma S, Selvadurai HJ, Lan X, Lee L, Kushida M, Voisin V, Whetstone H, So M, Aviv T, Park N, Zhu X, Xu C, Head R, Rowland KJ, Bernstein M, Clarke ID, Bader G, Harrington L, Brumell JH, Tyers M, Dirks PB.

Cancer Cell. 2016 Jun 13;29(6):859-873. doi: 10.1016/j.ccell.2016.05.002.

6.

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.

Gallo M, Coutinho FJ, Vanner RJ, Gayden T, Mack SC, Murison A, Remke M, Li R, Takayama N, Desai K, Lee L, Lan X, Park NI, Barsyte-Lovejoy D, Smil D, Sturm D, Kushida MM, Head R, Cusimano MD, Bernstein M, Clarke ID, Dick JE, Pfister SM, Rich JN, Arrowsmith CH, Taylor MD, Jabado N, Bazett-Jones DP, Lupien M, Dirks PB.

Cancer Cell. 2015 Dec 14;28(6):715-729. doi: 10.1016/j.ccell.2015.10.005. Epub 2015 Nov 25.

7.

Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.

Meyer M, Reimand J, Lan X, Head R, Zhu X, Kushida M, Bayani J, Pressey JC, Lionel AC, Clarke ID, Cusimano M, Squire JA, Scherer SW, Bernstein M, Woodin MA, Bader GD, Dirks PB.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):851-6. doi: 10.1073/pnas.1320611111. Epub 2015 Jan 5.

8.

ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.

Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, Taylor MD, Rutka JT, Jones C, Dirks PB, Zadeh G, Hawkins C.

Cancer Discov. 2014 Oct;4(10):1198-213. doi: 10.1158/2159-8290.CD-14-0157. Epub 2014 Aug 6.

9.

Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma.

Vanner RJ, Remke M, Gallo M, Selvadurai HJ, Coutinho F, Lee L, Kushida M, Head R, Morrissy S, Zhu X, Aviv T, Voisin V, Clarke ID, Li Y, Mungall AJ, Moore RA, Ma Y, Jones SJ, Marra MA, Malkin D, Northcott PA, Kool M, Pfister SM, Bader G, Hochedlinger K, Korshunov A, Taylor MD, Dirks PB.

Cancer Cell. 2014 Jul 14;26(1):33-47. doi: 10.1016/j.ccr.2014.05.005. Epub 2014 Jun 19.

10.

A tumorigenic MLL-homeobox network in human glioblastoma stem cells.

Gallo M, Ho J, Coutinho FJ, Vanner R, Lee L, Head R, Ling EK, Clarke ID, Dirks PB.

Cancer Res. 2013 Jan 1;73(1):417-27. doi: 10.1158/0008-5472.CAN-12-1881. Epub 2012 Oct 29.

11.

A GATA4-regulated tumor suppressor network represses formation of malignant human astrocytomas.

Agnihotri S, Wolf A, Munoz DM, Smith CJ, Gajadhar A, Restrepo A, Clarke ID, Fuller GN, Kesari S, Dirks PB, McGlade CJ, Stanford WL, Aldape K, Mischel PS, Hawkins C, Guha A.

J Exp Med. 2011 Apr 11;208(4):689-702. doi: 10.1084/jem.20102099. Epub 2011 Apr 4.

12.

MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy.

Rastegar M, Hotta A, Pasceri P, Makarem M, Cheung AY, Elliott S, Park KJ, Adachi M, Jones FS, Clarke ID, Dirks P, Ellis J.

PLoS One. 2009 Aug 27;4(8):e6810. doi: 10.1371/journal.pone.0006810.

13.

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.

Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A, Dirks P.

Cell Stem Cell. 2009 Jun 5;4(6):568-80. doi: 10.1016/j.stem.2009.03.014.

14.

Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma.

Ward RJ, Lee L, Graham K, Satkunendran T, Yoshikawa K, Ling E, Harper L, Austin R, Nieuwenhuis E, Clarke ID, Hui CC, Dirks PB.

Cancer Res. 2009 Jun 1;69(11):4682-90. doi: 10.1158/0008-5472.CAN-09-0342.

15.

Chemical genetics reveals a complex functional ground state of neural stem cells.

Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB.

Nat Chem Biol. 2007 May;3(5):268-73. Epub 2007 Apr 8.

PMID:
17417631
16.

IQGAP1 protein specifies amplifying cancer cells in glioblastoma multiforme.

Balenci L, Clarke ID, Dirks PB, Assard N, Ducray F, Jouvet A, Belin MF, Honnorat J, Baudier J.

Cancer Res. 2006 Sep 15;66(18):9074-82.

17.

Identification of human brain tumour initiating cells.

Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB.

Nature. 2004 Nov 18;432(7015):396-401.

18.

Cancer stem cells in nervous system tumors.

Singh SK, Clarke ID, Hide T, Dirks PB.

Oncogene. 2004 Sep 20;23(43):7267-73. Review.

PMID:
15378086
19.

Identification of a cancer stem cell in human brain tumors.

Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB.

Cancer Res. 2003 Sep 15;63(18):5821-8.

20.

A human brain tumor-derived PDGFR-alpha deletion mutant is transforming.

Clarke ID, Dirks PB.

Oncogene. 2003 Feb 6;22(5):722-33.

PMID:
12569364
21.

Murine xenogeneic immune responses to the human testis: a presumed immune-privileged tissue.

Kimmel SG, Ohbatake M, Kushida M, Merguerian P, Clarke ID, Kim PC.

Transplantation. 2000 Mar 27;69(6):1075-84.

PMID:
10762210
22.

T cells are necessary and critical for xenograft rejection in new concordant cardiac xenotransplant model.

Obatake M, Kushida M, Kimmel S, Clarke ID, Kim PC.

Transplantation. 1999 Jun 15;67(11):1480-4.

PMID:
10385090
23.

THE INACTIVATION OF MITOCHONDRIAL ENZYMES BY GAMMA RADIATION IN VITRO.

CLARKE ID, LANG J.

Radiat Res. 1965 Jan;24:142-53. No abstract available.

PMID:
14272809
24.

The effects of gamma-radiation on the protein content of apples and pears.

CLARKE ID, FERNANDES SJ.

Int J Appl Radiat Isot. 1961 Nov;11:186-9. No abstract available.

PMID:
13879760
25.

Effects of carbon dioxide on mitochondrial enzymes from Ricinus.

Ranson SL, Walker DA, Clarke ID.

Biochem J. 1960 Aug;76(2):216-21. No abstract available.

26.

Possible applications of ionizing radiations in the fruit, vegetable and related industries.

CLARKE ID.

Int J Appl Radiat Isot. 1959 Oct;6:175-81. No abstract available.

PMID:
13810507
27.

Microbial and other enzymes as depilatory agents.

CORDON TC, JONES HW, CLARKE ID, NAGHSKI J.

Appl Microbiol. 1958 Sep;6(5):293-7. No abstract available.

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