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Genetic Selection for Thermotolerance in Ruminants.

Osei-Amponsah R, Chauhan SS, Leury BJ, Cheng L, Cullen B, Clarke IJ, Dunshea FR.

Animals (Basel). 2019 Nov 11;9(11). pii: E948. doi: 10.3390/ani9110948. Review.


Stylistic variation on the Donald Trump Twitter account: A linguistic analysis of tweets posted between 2009 and 2018.

Clarke I, Grieve J.

PLoS One. 2019 Sep 25;14(9):e0222062. doi: 10.1371/journal.pone.0222062. eCollection 2019.


Perennial Ryegrass Alkaloids Increase Respiration Rate and Decrease Plasma Prolactin in Merino Sheep under Both Thermoneutral and Mild Heat Conditions.

Henry MLE, Kemp S, Clarke IJ, Dunshea FR, Leury BJ.

Toxins (Basel). 2019 Aug 19;11(8). pii: E479. doi: 10.3390/toxins11080479.


Amygdala NPY Circuits Promote the Development of Accelerated Obesity under Chronic Stress Conditions.

Ip CK, Zhang L, Farzi A, Qi Y, Clarke I, Reed F, Shi YC, Enriquez R, Dayas C, Graham B, Begg D, Brüning JC, Lee NJ, Hernandez-Sanchez D, Gopalasingam G, Koller J, Tasan R, Sperk G, Herzog H.

Cell Metab. 2019 Jul 2;30(1):111-128.e6. doi: 10.1016/j.cmet.2019.04.001. Epub 2019 Apr 25.


Growth kinetics of Chlamydia trachomatis in primary human Sertoli cells.

Filardo S, Skilton RJ, O'Neill CE, Di Pietro M, Sessa R, Clarke IN.

Sci Rep. 2019 Apr 10;9(1):5847. doi: 10.1038/s41598-019-42396-3.


Lipopolysaccharide reduces gonadotrophin-releasing hormone (GnRH) gene expression: role of RFamide-related peptide-3 and kisspeptin.

Lee CY, Li S, Li XF, Stalker DAE, Cooke C, Shao B, Kelestimur H, Henry BA, Conductier G, O'Byrne KT, Clarke IJ.

Reprod Fertil Dev. 2019 Mar 29. doi: 10.1071/RD18277. [Epub ahead of print]


Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.

Rajakulendran N, Rowland KJ, Selvadurai HJ, Ahmadi M, Park NI, Naumenko S, Dolma S, Ward RJ, So M, Lee L, MacLeod G, Pasiliao C, Brandon C, Clarke ID, Cusimano MD, Bernstein M, Batada N, Angers S, Dirks PB.

Genes Dev. 2019 May 1;33(9-10):498-510. doi: 10.1101/gad.321968.118. Epub 2019 Mar 6.


RANK deletion in neuropeptide Y neurones attenuates oestrogen deficiency-related bone loss.

Lee NJ, Clarke IM, Zengin A, Enriquez RF, Nagy V, Penninger JM, Baldock PA, Herzog H.

J Neuroendocrinol. 2019 Feb;31(2):e12687. doi: 10.1111/jne.12687. Epub 2019 Feb 1.


Genetic Transformation of a C. trachomatis Ocular Isolate With the Functional Tryptophan Synthase Operon Confers an Indole-Rescuable Phenotype.

O'Neill CE, Skilton RJ, Pearson SA, Filardo S, Andersson P, Clarke IN.

Front Cell Infect Microbiol. 2018 Dec 14;8:434. doi: 10.3389/fcimb.2018.00434. eCollection 2018.


Brown adipose tissue thermogenesis in polycystic ovary syndrome.

Shorakae S, Jona E, de Courten B, Lambert GW, Lambert EA, Phillips SE, Clarke IJ, Teede HJ, Henry BA.

Clin Endocrinol (Oxf). 2019 Mar;90(3):425-432. doi: 10.1111/cen.13913. Epub 2019 Jan 7.


Pseudotumor and Subsequent Implant Loosening as a Complication of Revision Total Hip Arthroplasty with Ceramic-on-Metal Bearing: A Case Report.

Naik LG, Shon WY, Clarke IC, Moon JG, Mukund P, Kim SM.

Hip Pelvis. 2018 Dec;30(4):276-281. doi: 10.5371/hp.2018.30.4.276. Epub 2018 Dec 6.


The Genetic Transformation of Chlamydia pneumoniae.

Shima K, Wanker M, Skilton RJ, Cutcliffe LT, Schnee C, Kohl TA, Niemann S, Geijo J, Klinger M, Timms P, Rattei T, Sachse K, Clarke IN, Rupp J.

mSphere. 2018 Oct 10;3(5). pii: e00412-18. doi: 10.1128/mSphere.00412-18.


Osteoglycin, a novel coordinator of bone and glucose homeostasis.

Lee NJ, Ali N, Zhang L, Qi Y, Clarke I, Enriquez RF, Brzozowska M, Lee IC, Rogers MJ, Laybutt DR, Center JR, Baldock PA, Herzog H.

Mol Metab. 2018 Jul;13:30-44. doi: 10.1016/j.molmet.2018.05.004. Epub 2018 May 8.


Estimating success of vaginal birth after caesarean section in a regional Australian population: Validation of a prediction model.

Mooney SS, Hiscock R, Clarke ID, Craig S.

Aust N Z J Obstet Gynaecol. 2019 Feb;59(1):66-70. doi: 10.1111/ajo.12809. Epub 2018 Apr 19.


The Chlamydia muridarum plasmid revisited : new insights into growth kinetics.

Skilton RJ, Wang Y, O'Neill C, Filardo S, Marsh P, Bénard A, Thomson NR, Ramsey KH, Clarke IN.

Wellcome Open Res. 2018 Mar 8;3:25. doi: 10.12688/wellcomeopenres.13905.1. eCollection 2018.


Stimulation of growth hormone by kisspeptin antagonists in ewes.

Smith JT, Roseweir A, Millar M, Clarke IJ, Millar RP.

J Endocrinol. 2018 May;237(2):165-173. doi: 10.1530/JOE-18-0074. Epub 2018 Mar 16.


Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity.

Last AR, Pickering H, Roberts CH, Coll F, Phelan J, Burr SE, Cassama E, Nabicassa M, Seth-Smith HMB, Hadfield J, Cutcliffe LT, Clarke IN, Mabey DCW, Bailey RL, Clark TG, Thomson NR, Holland MJ.

Genome Med. 2018 Feb 26;10(1):15. doi: 10.1186/s13073-018-0521-x.


Central RANK signalling in NPY neurons alters bone mass in male mice.

Lee NJ, Clarke IM, Enriquez RF, Nagy V, Penninger J, Baldock PA, Herzog H.

Neuropeptides. 2018 Apr;68:75-83. doi: 10.1016/j.npep.2018.02.004. Epub 2018 Feb 15.


Exercise counteracts the homeostatic decrease in thermogenesis caused by caloric restriction in sheep.

Fuller-Jackson JP, Clarke IJ, Rao A, Henry BA.

FASEB J. 2018 Jul;32(7):3859-3869. doi: 10.1096/fj.201701504R. Epub 2018 Feb 13.


Lowering of blood pressure after nitrate-rich vegetable consumption is abolished with the co-ingestion of thiocyanate-rich vegetables in healthy normotensive males.

Dewhurst-Trigg R, Yeates T, Blackwell JR, Thompson C, Linoby A, Morgan PT, Clarke I, Connolly LJ, Wylie LJ, Winyard PG, Jones AM, Bailey SJ.

Nitric Oxide. 2018 Apr 1;74:39-46. doi: 10.1016/j.niox.2018.01.009.


Continuous Kisspeptin Restores Luteinizing Hormone Pulsatility Following Cessation by a Neurokinin B Antagonist in Female Sheep.

Clarke IJ, Li Q, Henry BA, Millar RP.

Endocrinology. 2018 Feb 1;159(2):639-646. doi: 10.1210/en.2017-00737.


Mysterious inhibitory cell regulator investigated and found likely to be secretogranin II related.

Hart JE, Clarke IJ, Risbridger GP, Ferneyhough B, Vega-Hernández M.

PeerJ. 2017 Oct 13;5:e3833. doi: 10.7717/peerj.3833. eCollection 2017.


Glucocorticoid treatment facilitates development of a metabolic syndrome in ovariectomized Macaca Mulatta fed a high fat diet.

Li L, Yang G, Liao G, Mei J, Li L, Wang C, Yuan Y, Shi Y, Liu J, Zhong Z, Cheng J, Lu Y, Clarke IJ, Chen Y.

Steroids. 2017 Dec;128:105-113. doi: 10.1016/j.steroids.2017.09.005. Epub 2017 Oct 4.


Kisspeptin Stimulates Growth Hormone Release by Utilizing Neuropeptide Y Pathways and Is Dependent on the Presence of Ghrelin in the Ewe.

Foradori CD, Whitlock BK, Daniel JA, Zimmerman AD, Jones MA, Read CC, Steele BP, Smith JT, Clarke IJ, Elsasser TH, Keisler DH, Sartin JL.

Endocrinology. 2017 Oct 1;158(10):3526-3539. doi: 10.1210/en.2017-00303.


ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB.

Cell Stem Cell. 2017 Sep 7;21(3):411. doi: 10.1016/j.stem.2017.08.008. No abstract available.


Alteration in the relationship between tanycytes and gonadotrophin-releasing hormone neurosecretory terminals following long-term metabolic manipulation in the sheep.

Pouchain Ribeiro Neto R, Clarke IJ, Conductier G.

J Neuroendocrinol. 2017 Oct;29(10). doi: 10.1111/jne.12509.


ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB.

Cell Stem Cell. 2017 Aug 3;21(2):209-224.e7. doi: 10.1016/j.stem.2017.06.004. Epub 2017 Jul 14. Erratum in: Cell Stem Cell. 2017 Sep 7;21(3):411.


Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion.

Hadfield J, Harris SR, Seth-Smith HMB, Parmar S, Andersson P, Giffard PM, Schachter J, Moncada J, Ellison L, Vaulet MLG, Fermepin MR, Radebe F, Mendoza S, Ouburg S, Morré SA, Sachse K, Puolakkainen M, Korhonen SJ, Sonnex C, Wiggins R, Jalal H, Brunelli T, Casprini P, Pitt R, Ison C, Savicheva A, Shipitsyna E, Hadad R, Kari L, Burton MJ, Mabey D, Solomon AW, Lewis D, Marsh P, Unemo M, Clarke IN, Parkhill J, Thomson NR.

Genome Res. 2017 Jul;27(7):1220-1229. doi: 10.1101/gr.212647.116. Epub 2017 Jun 6.


Is centrally induced alveolar bone loss in a large animal model preventable by peripheral hormone substitution?

Simon MJK, Beil FT, Pogoda P, Vettorazzi E, Clarke I, Amling M, Oheim R.

Clin Oral Investig. 2018 Jan;22(1):495-503. doi: 10.1007/s00784-017-2138-7. Epub 2017 Jun 2.


Ontogeny and Thermogenic Role for Sternal Fat in Female Sheep.

Henry BA, Pope M, Birtwistle M, Loughnan R, Alagal R, Fuller-Jackson JP, Perry V, Budge H, Clarke IJ, Symonds ME.

Endocrinology. 2017 Jul 1;158(7):2212-2225. doi: 10.1210/en.2017-00081.


Effects of Season and Estradiol on KNDy Neuron Peptides, Colocalization With D2 Dopamine Receptors, and Dopaminergic Inputs in the Ewe.

Weems P, Smith J, Clarke IJ, Coolen LM, Goodman RL, Lehman MN.

Endocrinology. 2017 Apr 1;158(4):831-841. doi: 10.1210/en.2016-1830.


Development and evaluation of an enzyme-linked immunosorbent assay for the detection of antibodies to a common urogenital derivative of Chlamydia trachomatis plasmid-encoded PGP3.

Winstanley CE, Ramsey KH, Marsh P, Clarke IN.

J Immunol Methods. 2017 Jun;445:23-30. doi: 10.1016/j.jim.2017.03.002. Epub 2017 Mar 7.


Sheep model for osteoporosis: The effects of peripheral hormone therapy on centrally induced systemic bone loss in an osteoporotic sheep model.

Oheim R, Simon MJK, Steiner M, Vettorazzi E, Barvencik F, Ignatius A, Amling M, Clarke IJ, Pogoda P, Beil FT.

Injury. 2017 Apr;48(4):841-848. doi: 10.1016/j.injury.2017.02.009. Epub 2017 Feb 20.


Effect of gonadotropin-inhibitory hormone on luteinizing hormone secretion in humans.

George JT, Hendrikse M, Veldhuis JD, Clarke IJ, Anderson RA, Millar RP.

Clin Endocrinol (Oxf). 2017 May;86(5):731-738. doi: 10.1111/cen.13308. Epub 2017 Mar 26.


Mid-term results of ReCap/Magnum/Taperloc metal-on-metal total hip arthroplasty with mean follow-up of 7.1 years.

Koutalos AA, Kourtis A, Clarke IC, Smith EJ.

Hip Int. 2017 May 12;27(3):226-234. doi: 10.5301/hipint.5000454. Epub 2016 Dec 2.


Clinical Characteristics and Short-Term Outcomes of HIV Patients Admitted to an African Intensive Care Unit.

Kwizera A, Nabukenya M, Peter A, Semogerere L, Ayebale E, Katabira C, Kizito S, Nantume C, Clarke I, Nakibuuka J.

Crit Care Res Pract. 2016;2016:2610873. Epub 2016 Oct 9.


Stress Increases Gonadotropin Inhibitory Hormone Cell Activity and Input to GnRH Cells in Ewes.

Clarke IJ, Bartolini D, Conductier G, Henry BA.

Endocrinology. 2016 Nov;157(11):4339-4350. Epub 2016 Sep 9.


α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors.

Enriori PJ, Chen W, Garcia-Rudaz MC, Grayson BE, Evans AE, Comstock SM, Gebhardt U, Müller HL, Reinehr T, Henry BA, Brown RD, Bruce CR, Simonds SE, Litwak SA, McGee SL, Luquet S, Martinez S, Jastroch M, Tschöp MH, Watt MJ, Clarke IJ, Roth CL, Grove KL, Cowley MA.

Mol Metab. 2016 Aug 5;5(10):807-822. doi: 10.1016/j.molmet.2016.07.009. eCollection 2016 Oct.


The F0F1 ATP Synthase Complex Localizes to Membrane Rafts in Gonadotrope Cells.

Allen-Worthington K, Xie J, Brown JL, Edmunson AM, Dowling A, Navratil AM, Scavelli K, Yoon H, Kim DG, Bynoe MS, Clarke I, Roberson MS.

Mol Endocrinol. 2016 Sep;30(9):996-1011. doi: 10.1210/me.2015-1324. Epub 2016 Aug 2.


Ewes With Divergent Cortisol Responses to ACTH Exhibit Functional Differences in the Hypothalamo-Pituitary-Adrenal (HPA) Axis.

Hewagalamulage SD, Clarke IJ, Rao A, Henry BA.

Endocrinology. 2016 Sep;157(9):3540-9. doi: 10.1210/en.2016-1287. Epub 2016 Jul 14.


New concepts of the central control of reproduction, integrating influence of stress, metabolic state, and season.

Clarke IJ, Arbabi L.

Domest Anim Endocrinol. 2016 Jul;56 Suppl:S165-79. doi: 10.1016/j.domaniend.2016.03.001. Review.


Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity.

Hewagalamulage SD, Lee TK, Clarke IJ, Henry BA.

Domest Anim Endocrinol. 2016 Jul;56 Suppl:S112-20. doi: 10.1016/j.domaniend.2016.03.004. Epub 2016 Mar 31. Review.


Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.

Dolma S, Selvadurai HJ, Lan X, Lee L, Kushida M, Voisin V, Whetstone H, So M, Aviv T, Park N, Zhu X, Xu C, Head R, Rowland KJ, Bernstein M, Clarke ID, Bader G, Harrington L, Brumell JH, Tyers M, Dirks PB.

Cancer Cell. 2016 Jun 13;29(6):859-873. doi: 10.1016/j.ccell.2016.05.002.


Triiodothyronine Administration in a Model of Septic Shock: A Randomized Blinded Placebo-Controlled Trial.

Maiden MJ, Chapman MJ, Torpy DJ, Kuchel TR, Clarke IJ, Nash CH, Fraser JD, Ludbrook GL.

Crit Care Med. 2016 Jun;44(6):1153-60. doi: 10.1097/CCM.0000000000001644.


Chlamydia trachomatis from Australian Aboriginal people with trachoma are polyphyletic composed of multiple distinctive lineages.

Andersson P, Harris SR, Smith HMBS, Hadfield J, O'Neill C, Cutcliffe LT, Douglas FP, Asche LV, Mathews JD, Hutton SI, Sarovich DS, Tong SYC, Clarke IN, Thomson NR, Giffard PM.

Nat Commun. 2016 Feb 25;7:10688. doi: 10.1038/ncomms10688.


Expression of regulatory neuropeptides in the hypothalamus of red deer (Cervus elaphus) reveals anomalous relationships in the seasonal control of appetite and reproduction.

Barrell GK, Ridgway MJ, Wellby M, Pereira A, Henry BA, Clarke IJ.

Gen Comp Endocrinol. 2016 Apr 1;229:1-7. doi: 10.1016/j.ygcen.2016.02.020. Epub 2016 Feb 17.


Quantitative Proteomics of the Infectious and Replicative Forms of Chlamydia trachomatis.

Skipp PJ, Hughes C, McKenna T, Edwards R, Langridge J, Thomson NR, Clarke IN.

PLoS One. 2016 Feb 12;11(2):e0149011. doi: 10.1371/journal.pone.0149011. eCollection 2016.


Investigating the efficacy of a whole team, psychologically informed, acute mental health service approach.

Araci D, Clarke I.

J Ment Health. 2017 Aug;26(4):307-311. doi: 10.3109/09638237.2016.1139065. Epub 2016 Feb 8.


Collective selection of food patches in Drosophila.

Lihoreau M, Clarke IM, Buhl J, Sumpter DJ, Simpson SJ.

J Exp Biol. 2016 Mar;219(Pt 5):668-75. doi: 10.1242/jeb.127431. Epub 2016 Jan 8.

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