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Topoisomerase II SUMOylation activates a metaphase checkpoint via Haspin and Aurora B kinases.

Pandey N, Keifenheim D, Yoshida MM, Hassebroek VA, Soroka C, Azuma Y, Clarke DJ.

J Cell Biol. 2019 Nov 11. pii: jcb.201807189. doi: 10.1083/jcb.201807189. [Epub ahead of print]


Resolving Ultrafast Spin-Orbit Dynamics in Heavy Many-Electron Atoms.

Wragg J, Clarke DDA, Armstrong GSJ, Brown AC, Ballance CP, van der Hart HW.

Phys Rev Lett. 2019 Oct 18;123(16):163001. doi: 10.1103/PhysRevLett.123.163001.


LINCS Data Portal 2.0: next generation access point for perturbation-response signatures.

Stathias V, Turner J, Koleti A, Vidovic D, Cooper D, Fazel-Najafabadi M, Pilarczyk M, Terryn R, Chung C, Umeano A, Clarke DJB, Lachmann A, Evangelista JE, Ma'ayan A, Medvedovic M, Schürer SC.

Nucleic Acids Res. 2019 Nov 8. pii: gkz1023. doi: 10.1093/nar/gkz1023. [Epub ahead of print]


Controlled flight of a microrobot powered by soft artificial muscles.

Chen Y, Zhao H, Mao J, Chirarattananon P, Helbling EF, Hyun NP, Clarke DR, Wood RJ.

Nature. 2019 Nov 4. doi: 10.1038/s41586-019-1737-7. [Epub ahead of print]


FAIRshake: Toolkit to Evaluate the FAIRness of Research Digital Resources.

Clarke DJB, Wang L, Jones A, Wojciechowicz ML, Torre D, Jagodnik KM, Jenkins SL, McQuilton P, Flamholz Z, Silverstein MC, Schilder BM, Robasky K, Castillo C, Idaszak R, Ahalt SC, Williams J, Schurer S, Cooper DJ, de Miranda Azevedo R, Klenk JA, Haendel MA, Nedzel J, Avillach P, Shimoyama ME, Harris RM, Gamble M, Poten R, Charbonneau AL, Larkin J, Brown CT, Bonazzi VR, Dumontier MJ, Sansone SA, Ma'ayan A.

Cell Syst. 2019 Oct 10. pii: S2405-4712(19)30345-X. doi: 10.1016/j.cels.2019.09.011. [Epub ahead of print]


Traumatic renal injury: Five-year experience at a major trauma centre in South Africa.

Salem MS, Urry RJ, Kong VY, Clarke DL, Bruce J, Laing GL.

Injury. 2019 Oct 19. pii: S0020-1383(19)30635-7. doi: 10.1016/j.injury.2019.10.034. [Epub ahead of print]


Supporting carers of stroke survivors to reduce carer burden: development of the Preparing is Caring intervention using Intervention Mapping.

Hall JF, Crocker TF, Clarke DJ, Forster A.

BMC Public Health. 2019 Oct 29;19(1):1408. doi: 10.1186/s12889-019-7615-2.


Use of Modeling and Simulations to Determine Raltegravir Dosing in Neonates: A Model for Safely and Efficiently Determining Appropriate Neonatal Dosing Regimens: IMPAACT P1110.

Clarke DF, Mirochnick M, Acosta EP, Capparelli E, Chain A, Teppler H, Smith B, Lommerse J; International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1110 Study Team.

J Acquir Immune Defic Syndr. 2019 Dec 1;82(4):392-398. doi: 10.1097/QAI.0000000000002149.


New anthropometric evidence on living standards in nineteenth-century Chile.

Llorca-Jaña M, Clarke D, Navarrete-Montalvo J, Araya-Valenzuela R, Allende M.

Econ Hum Biol. 2019 Sep 28:100819. doi: 10.1016/j.ehb.2019.100819. [Epub ahead of print]


The Combined SIRS + qSOFA (qSIRS) Score is More Accurate Than qSOFA Alone in Predicting Mortality in Patients with Surgical Sepsis in an LMIC Emergency Department.

Green SL, Smith MTD, Cairns C, Clarke DL, Bruce J, Bekker W, Kong V, Laing GL.

World J Surg. 2019 Oct 22. doi: 10.1007/s00268-019-05181-x. [Epub ahead of print]


An analysis of adverse events and human error associated with the imaging of patients at a major trauma centre in South Africa.

Bashir AA, Kong VY, Buitendag JJP, Manchev V, Bekker W, Bruce JL, Laing GL, Brysiewicz P, Clarke DL.

S Afr Med J. 2019 Aug 28;109(9):693-697. doi: 10.7196/SAMJ.2019.v109i9.13726.


Role of the Photorhabdus Dam methyltransferase during interactions with its invertebrate hosts.

Payelleville A, Blackburn D, Lanois A, Pagès S, Cambon MC, Ginibre N, Clarke DJ, Givaudan A, Brillard J.

PLoS One. 2019 Oct 9;14(10):e0212655. doi: 10.1371/journal.pone.0212655. eCollection 2019.


Nigral overexpression of α-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome.

O'Donovan SM, Crowley EK, Brown JR, O'Sullivan O, O'Leary OF, Timmons S, Nolan YM, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O'Neill C.

Neurogastroenterol Motil. 2019 Oct 2:e13726. doi: 10.1111/nmo.13726. [Epub ahead of print]


Evaluation of benazepril in cats with heart disease in a prospective, randomized, blinded, placebo-controlled clinical trial.

King JN, Martin M, Chetboul V, Ferasin L, French AT, Strehlau G, Seewald W, Smith SGW, Swift ST, Roberts SL, Harvey AM, Little CJL, Caney SMA, Simpson KE, Sparkes AH, Mardell EJ, Bomassi E, Muller C, Sauvage JP, Diquélou A, Schneider MA, Brown LJ, Clarke DD, Rousselot JF.

J Vet Intern Med. 2019 Sep 27. doi: 10.1111/jvim.15572. [Epub ahead of print]


A protocol for a systematic review of process evaluations of interventions investigating sedentary behaviour in adults.

Corepal R, Hall JF, English C, Farrin A, Fitzsimons CF, Forster A, Lawton R, Mead G, Clarke D.

BMJ Open. 2019 Sep 18;9(9):e031291. doi: 10.1136/bmjopen-2019-031291.


Utilization of Age-Adjusted Shock Index in a Resource-Strained Setting.

Traynor MD Jr, Hernandez MC, Clarke DL, Kong VY, Habermann EB, Polites SF, Laing GL, Bruce JL, Zielinski MD, Ishitani MB, Moir CR.

J Pediatr Surg. 2019 Aug 30. pii: S0022-3468(19)30561-5. doi: 10.1016/j.jpedsurg.2019.08.021. [Epub ahead of print]


The pyrenoidal linker protein EPYC1 phase separates with hybrid Arabidopsis-Chlamydomonas Rubisco through interactions with the algal Rubisco small subunit.

Atkinson N, Velanis CN, Wunder T, Clarke DJ, Mueller-Cajar O, McCormick AJ.

J Exp Bot. 2019 Oct 15;70(19):5271-5285. doi: 10.1093/jxb/erz275.


Complete recovery following transorbital penetrating head injury traversing the brainstem: case report.

MacLean MA, Mukhida K, Shankar JJS, Schmidt MH, Clarke DB.

J Neurosurg Pediatr. 2019 Sep 6:1-5. doi: 10.3171/2019.6.PEDS19106. [Epub ahead of print]


Native Ion Mobility Mass Spectrometry (IM-MS) reveals that small organic acid fragments impart gas-phase stability to carbonic anhydrase II.

Veale CGL, Mateos Jimenez M, Mackay CL, Clarke DJ.

Rapid Commun Mass Spectrom. 2019 Sep 3. doi: 10.1002/rcm.8570. [Epub ahead of print]


On the influence of rotational motion on MRI velocimetry of granular flows - Theoretical predictions and comparison to experimental data.

Clarke DA, Fabich HT, Brox TI, Galvosas P, Holland DJ.

J Magn Reson. 2019 Oct;307:106569. doi: 10.1016/j.jmr.2019.106569. Epub 2019 Aug 10.


Leveraging protein dynamics to identify cancer mutational hotspots using 3D structures.

Kumar S, Clarke D, Gerstein MB.

Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):18962-18970. doi: 10.1073/pnas.1901156116. Epub 2019 Aug 28.


Catalytic Knockdown of miR-21 by Artificial Ribonuclease: Biological Performance in Tumor Model.

Patutina OA, Miroshnichenko SK, Mironova NL, Sen'kova AV, Bichenkova EV, Clarke DJ, Vlassov VV, Zenkova MA.

Front Pharmacol. 2019 Aug 8;10:879. doi: 10.3389/fphar.2019.00879. eCollection 2019.


Predictors of Increases in Alcohol Problems and Alcohol Use Disorders in Offspring in the San Diego Prospective Study.

Schuckit MA, Smith TL, Clarke D, Mendoza LA, Kawamura M, Schoen L.

Alcohol Clin Exp Res. 2019 Oct;43(10):2232-2241. doi: 10.1111/acer.14164. Epub 2019 Aug 27.


Exploring adults' experiences of sedentary behaviour and participation in non-workplace interventions designed to reduce sedentary behaviour: a thematic synthesis of qualitative studies.

Rawlings GH, Williams RK, Clarke DJ, English C, Fitzsimons C, Holloway I, Lawton R, Mead G, Patel A, Forster A.

BMC Public Health. 2019 Aug 13;19(1):1099. doi: 10.1186/s12889-019-7365-1. Review.


Developing a blueprint for a civilian-military collaborative program in trauma training for Northern European countries: A South African experience.

van der Wal H, van Dongen TTCF, Vermeulen CFW, Bruce JL, Bekker W, Manchev V, Kong V, van Waes O, Clarke DL, Hoencamp R.

Injury. 2019 Aug 1. pii: S0020-1383(19)30450-4. doi: 10.1016/j.injury.2019.07.034. [Epub ahead of print]


The spectrum of animal related injuries managed at a major trauma centre in South Africa.

Wessels EU, Kong VY, Buitendag J, Moffatt S, Weale R, Ras AB, Ras M, Smith MTD, Laing GL, Bruce JL, Bekker W, Manchev V, Clarke DL.

S Afr J Surg. 2019 Sep;57(3):54.


rVSVΔG-ZEBOV-GP (also designated V920) recombinant vesicular stomatitis virus pseudotyped with Ebola Zaire Glycoprotein: Standardized template with key considerations for a risk/benefit assessment.

Monath TP, Fast PE, Modjarrad K, Clarke DK, Martin BK, Fusco J, Nichols R, Heppner DG, Simon JK, Dubey S, Troth SP, Wolf J, Singh V, Coller BA, Robertson JS; Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG).

Vaccine X. 2019 Jan 29;1:100009. doi: 10.1016/j.jvacx.2019.100009. eCollection 2019 Apr 11.


Erratum: Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase.

Harrison PJ, Gable K, Somashekarappa N, Kelly V, Clarke DJ, Naismith JH, Dunn TM, Campopiano DJ.

J Lipid Res. 2019 Aug;60(8):1489. doi: 10.1194/jlr.ERR119000228. No abstract available.


The spectrum of self inflicted injuries managed at a major trauma centre in South Africa.

Moffatt SE, Kong VY, Weale RD, Buitendag JP, Ras AB, Ras M, Smith M, Bruce JL, Laing GL, Clarke DL.

S Afr J Surg. 2019 Jun;57(2):65.


Hyperlactataemia with acute kidney injury following community assault: cause or effect?

Skinner DL, Lewis C, de Vasconcellos K, Bruce J, Laing G, Clarke D, Muckart D.

S Afr J Surg. 2019 Jun;57(2):63.


Quantifying the burden of trauma imaging on the CT scan service at a major trauma centre in South Africa.

Bashir AA, Kong VY, Weale RD, Bruce JL, Laing GL, Bekker W, Clarke DL.

S Afr J Surg. 2019 Jun;57(2):48-53.


A comparison of oesophageal cancer between the public and private sectors in KwaZulu-Natal.

Lutakwa A, Loots E, Smith MT, Clarke DL.

S Afr J Surg. 2019 Jun;57(2):16-19.


Artificial β-propeller protein-based hydrolases.

Clarke DE, Noguchi H, Gryspeerdt JAG, De Feyter S, Voet ARD.

Chem Commun (Camb). 2019 Jul 23;55(60):8880-8883. doi: 10.1039/c9cc04388h.


Ten Years of Data Verification: The Society of Thoracic Surgeons Congenital Heart Surgery Database Audits.

Overman DM, Jacobs ML, O'Brien JE Jr, Kumar SR, Mayer JE Jr, Ebel A, Clarke DR, Jacobs JP.

World J Pediatr Congenit Heart Surg. 2019 Jul;10(4):454-463. doi: 10.1177/2150135119845256. Review.


Esophagostomy tube complications in dogs and cats: Retrospective review of 225 cases.

Nathanson O, McGonigle K, Michel K, Stefanovski D, Clarke D.

J Vet Intern Med. 2019 Sep;33(5):2014-2019. doi: 10.1111/jvim.15563. Epub 2019 Jul 11.


How do stroke survivors with communication difficulties manage life after stroke in the first year? A qualitative study.

Wray F, Clarke D, Forster A.

Int J Lang Commun Disord. 2019 Sep;54(5):814-827. doi: 10.1111/1460-6984.12487. Epub 2019 Jul 4.


Untargeted Metabolite Mapping in 3D Cell Culture Models Using High Spectral Resolution FT-ICR Mass Spectrometry Imaging.

Tucker LH, Hamm GR, Sargeant RJE, Goodwin RJA, Mackay CL, Campbell CJ, Clarke DJ.

Anal Chem. 2019 Aug 6;91(15):9522-9529. doi: 10.1021/acs.analchem.9b00661. Epub 2019 Jul 16.


Tonantzin, a New Genus of Bess Beetle (Coleoptera, Passalidae) from a Montane Subtropical Forest in Central Mexico, with a Review of the Taxonomic Significance of the Mesofrontal Structure in Proculini.

Beza-Beza CF, Jiménez-Ferbans L, Clarke DJ, Reyes-Castillo P, McKenna DD.

Insects. 2019 Jun 28;10(7). pii: E188. doi: 10.3390/insects10070188.


Sequence-Specific Detection of Unlabeled Nucleic Acid Biomarkers Using a "One-Pot" 3D Molecular Sensor.

Yousaf S, King PJS, Miller AF, Saiani A, Clarke DJ, Trivoluzzi LT, Aojula HS, Bichenkova EV.

Anal Chem. 2019 Aug 6;91(15):10016-10025. doi: 10.1021/acs.analchem.9b01841. Epub 2019 Jul 11.


Damage control or definitive repair? A retrospective review of abdominal trauma at a major trauma center in South Africa.

Weale R, Kong V, Buitendag J, Ras A, Blodgett J, Laing G, Bruce J, Bekker W, Manchev V, Clarke D.

Trauma Surg Acute Care Open. 2019 Apr 16;4(1):e000235. doi: 10.1136/tsaco-2018-000235. eCollection 2019.


Analgesia protocols for burns dressings: Challenges with implementation.

Wall SL, Clarke DL, Allorto NL.

Burns. 2019 Nov;45(7):1680-1684. doi: 10.1016/j.burns.2019.04.012. Epub 2019 Jun 21.


Isolated free fluid on computed tomography for blunt abdominal trauma.

Bekker W, Smith M, Kong VY, Bruce JL, Laing G, Manchev V, Clarke DL.

Ann R Coll Surg Engl. 2019 Nov;101(8):552-557. doi: 10.1308/rcsann.2019.0078. Epub 2019 Jun 20.


Maternal-Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing.

Lommerse J, Clarke D, Kerbusch T, Merdjan H, Witjes H, Teppler H, Mirochnick M, Acosta EP, Wenning L, Nachman S, Chain A.

CPT Pharmacometrics Syst Pharmacol. 2019 Sep;8(9):643-653. doi: 10.1002/psp4.12443. Epub 2019 Jul 10.


Ureteric inguinal herniation with obstructing bladder tumour.

Harley F, Kinnear N, Ravindran S, Clarke D, Yao HH.

Urol Case Rep. 2019 May 30;26:100924. doi: 10.1016/j.eucr.2019.100924. eCollection 2019 Sep.


The private sector and universal health coverage.

Clarke D, Doerr S, Hunter M, Schmets G, Soucat A, Paviza A.

Bull World Health Organ. 2019 Jun 1;97(6):434-435. doi: 10.2471/BLT.18.225540. Epub 2019 Apr 1. No abstract available.


Aryl-viologen pentapeptide self-assembled conductive nanofibers.

Clarke DE, Olesińska M, Mönch T, Schoenaers B, Stesmans A, Scherman OA.

Chem Commun (Camb). 2019 Jun 20;55(51):7354-7357. doi: 10.1039/c9cc00862d.


A Brief History of Single-Particle Tracking of the Epidermal Growth Factor Receptor.

Clarke DT, Martin-Fernandez ML.

Methods Protoc. 2019 Jan 30;2(1). pii: E12. doi: 10.3390/mps2010012. Review.


Microglial cell hyper-ramification and neuronal dendritic spine loss in the hippocampus and medial prefrontal cortex in a mouse model of PTSD.

Smith KL, Kassem MS, Clarke DJ, Kuligowski MP, Bedoya-Pérez MA, Todd SM, Lagopoulos J, Bennett MR, Arnold JC.

Brain Behav Immun. 2019 Aug;80:889-899. doi: 10.1016/j.bbi.2019.05.042. Epub 2019 May 31.


Radiation exposure of dogs and cats undergoing fluoroscopic procedures and for operators performing those procedures.

Hersh-Boyle RA, Culp WTN, Brown DC, Luskin AC, Kapatkin AS, Chou PY, Agnello KA, Reetz JA, Oyama MA, Visser LC, Palm CA, Clarke DL.

Am J Vet Res. 2019 Jun;80(6):558-564. doi: 10.2460/ajvr.80.6.558.


Neural Network Based Uncertainty Prediction for Autonomous Vehicle Application.

Zhang F, Martinez CM, Clarke D, Cao D, Knoll A.

Front Neurorobot. 2019 May 10;13:12. doi: 10.3389/fnbot.2019.00012. eCollection 2019.

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