Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 121

1.

Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice.

Widmeier E, Airik M, Hugo H, Schapiro D, Wedel J, Ghosh CC, Nakayama M, Schneider R, Awad AM, Nag A, Cho J, Schueler M, Clarke CF, Airik R, Hildebrandt F.

J Am Soc Nephrol. 2019 Feb 8. pii: ASN.2018060625. doi: 10.1681/ASN.2018060625. [Epub ahead of print]

PMID:
30737270
2.

Standardization of Outpatient Procedure (STOP) Narcotics: A Prospective Non-Inferiority Study to Reduce Opioid Use in Outpatient General Surgical Procedures.

Hartford LB, Van Koughnett JAM, Murphy PB, Vogt KN, Hilsden RJ, Clarke CF, Allen LJ, Gray SD, Parry NG, Gray DK, Leslie KA.

J Am Coll Surg. 2019 Jan;228(1):81-88.e1. doi: 10.1016/j.jamcollsurg.2018.09.008. Epub 2018 Oct 22.

PMID:
30359828
3.

Coenzyme Q10 deficiencies: pathways in yeast and humans.

Awad AM, Bradley MC, Fernández-Del-Río L, Nag A, Tsui HS, Clarke CF.

Essays Biochem. 2018 Jul 20;62(3):361-376. doi: 10.1042/EBC20170106. Print 2018 Jul 20. Review.

4.

Insights into an Ancient Atypical Kinase Essential for Biosynthesis of Coenzyme Q.

Clarke CF.

Cell Chem Biol. 2018 Feb 15;25(2):123-125. doi: 10.1016/j.chembiol.2018.02.001.

PMID:
29452608
5.

Chromatin-remodeling SWI/SNF complex regulates coenzyme Q6 synthesis and a metabolic shift to respiration in yeast.

Awad AM, Venkataramanan S, Nag A, Galivanche AR, Bradley MC, Neves LT, Douglass S, Clarke CF, Johnson TL.

J Biol Chem. 2017 Sep 8;292(36):14851-14866. doi: 10.1074/jbc.M117.798397. Epub 2017 Jul 24.

6.

Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-Synthome.

He CH, Black DS, Allan CM, Meunier B, Rahman S, Clarke CF.

Front Physiol. 2017 Jul 7;8:463. doi: 10.3389/fphys.2017.00463. eCollection 2017.

7.

Neuraxial drug delivery for the management of cancer pain: cost, updates, and society guidelines.

Clarke CFM.

Curr Opin Anaesthesiol. 2017 Oct;30(5):593-597. doi: 10.1097/ACO.0000000000000497. Review.

PMID:
28731876
8.

Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.

Fernández-Del-Río L, Nag A, Gutiérrez Casado E, Ariza J, Awad AM, Joseph AI, Kwon O, Verdin E, de Cabo R, Schneider C, Torres JZ, Burón MI, Clarke CF, Villalba JM.

Free Radic Biol Med. 2017 Sep;110:176-187. doi: 10.1016/j.freeradbiomed.2017.06.006. Epub 2017 Jun 9.

9.

Biochemistry: Unexpected role for vitamin B2.

Clarke CF, Allan CM.

Nature. 2015 Jun 25;522(7557):427-8. doi: 10.1038/nature14536. Epub 2015 Jun 17. No abstract available.

PMID:
26083748
10.

Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid.

He CH, Black DS, Nguyen TP, Wang C, Srinivasan C, Clarke CF.

Biochim Biophys Acta. 2015 Sep;1851(9):1227-39. doi: 10.1016/j.bbalip.2015.05.003. Epub 2015 May 23.

11.

Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis.

Xie LX, Williams KJ, He CH, Weng E, Khong S, Rose TE, Kwon O, Bensinger SJ, Marbois BN, Clarke CF.

J Lipid Res. 2015 Apr;56(4):909-19. doi: 10.1194/jlr.M057919. Epub 2015 Feb 14.

12.

Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae.

Allan CM, Awad AM, Johnson JS, Shirasaki DI, Wang C, Blaby-Haas CE, Merchant SS, Loo JA, Clarke CF.

J Biol Chem. 2015 Mar 20;290(12):7517-34. doi: 10.1074/jbc.M114.633131. Epub 2015 Jan 28.

13.

Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress.

Andreyev AY, Tsui HS, Milne GL, Shmanai VV, Bekish AV, Fomich MA, Pham MN, Nong Y, Murphy AN, Clarke CF, Shchepinov MS.

Free Radic Biol Med. 2015 May;82:63-72. doi: 10.1016/j.freeradbiomed.2014.12.023. Epub 2015 Jan 8.

PMID:
25578654
14.

Reply to Wang et al response to 'Evaluation of New Zealand's bicycle helmet law' article.

Clarke CF.

N Z Med J. 2014 Sep 12;127(1402):113-6. No abstract available.

PMID:
25228427
15.

Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis.

Nguyen TP, Casarin A, Desbats MA, Doimo M, Trevisson E, Santos-Ocaña C, Navas P, Clarke CF, Salviati L.

Biochim Biophys Acta. 2014 Nov;1841(11):1628-38. doi: 10.1016/j.bbalip.2014.08.007. Epub 2014 Aug 23.

16.

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.

Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J.

Nature. 2014 Jun 19;510(7505):397-401. doi: 10.1038/nature13264. Epub 2014 May 14.

17.

Osmotic stress: Is CoQ a membrane stabilizer?

Clarke CF, Rowat AC, Gober JW.

Nat Chem Biol. 2014 Apr;10(4):242-3. doi: 10.1038/nchembio.1478. No abstract available.

PMID:
24643237
18.

Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.

He CH, Xie LX, Allan CM, Tran UC, Clarke CF.

Biochim Biophys Acta. 2014 Apr 4;1841(4):630-44. doi: 10.1016/j.bbalip.2013.12.017. Epub 2014 Jan 7.

19.

Unusual kinetic isotope effects of deuterium reinforced polyunsaturated fatty acids in tocopherol-mediated free radical chain oxidations.

Lamberson CR, Xu L, Muchalski H, Montenegro-Burke JR, Shmanai VV, Bekish AV, McLean JA, Clarke CF, Shchepinov MS, Porter NA.

J Am Chem Soc. 2014 Jan 22;136(3):838-41. doi: 10.1021/ja410569g. Epub 2014 Jan 8.

20.

ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption.

Ashraf S, Gee HY, Woerner S, Xie LX, Vega-Warner V, Lovric S, Fang H, Song X, Cattran DC, Avila-Casado C, Paterson AD, Nitschké P, Bole-Feysot C, Cochat P, Esteve-Rudd J, Haberberger B, Allen SJ, Zhou W, Airik R, Otto EA, Barua M, Al-Hamed MH, Kari JA, Evans J, Bierzynska A, Saleem MA, Böckenhauer D, Kleta R, El Desoky S, Hacihamdioglu DO, Gok F, Washburn J, Wiggins RC, Choi M, Lifton RP, Levy S, Han Z, Salviati L, Prokisch H, Williams DS, Pollak M, Clarke CF, Pei Y, Antignac C, Hildebrandt F.

J Clin Invest. 2013 Dec;123(12):5179-89. doi: 10.1172/JCI69000. Epub 2013 Nov 25.

21.

Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q10.

Gasser DL, Winkler CA, Peng M, An P, McKenzie LM, Kirk GD, Shi Y, Xie LX, Marbois BN, Clarke CF, Kopp JB.

Am J Physiol Renal Physiol. 2013 Oct 15;305(8):F1228-38. doi: 10.1152/ajprenal.00143.2013. Epub 2013 Aug 7.

22.

Functional imaging for interpretation of pain pathways: current clinical application/relevance and future initiatives.

Clarke CF, Lawrence KS.

Curr Pain Headache Rep. 2013 Feb;17(2):311. doi: 10.1007/s11916-012-0311-x. Review.

PMID:
23315051
23.

A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae.

Allan CM, Hill S, Morvaridi S, Saiki R, Johnson JS, Liau WS, Hirano K, Kawashima T, Ji Z, Loo JA, Shepherd JN, Clarke CF.

Biochim Biophys Acta. 2013 Apr;1831(4):776-791. doi: 10.1016/j.bbalip.2012.12.007. Epub 2012 Dec 25.

24.

Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli.

Gomez F, Monsalve GC, Tse V, Saiki R, Weng E, Lee L, Srinivasan C, Frand AR, Clarke CF.

BMC Microbiol. 2012 Dec 20;12:300. doi: 10.1186/1471-2180-12-300.

25.

Case report: Emergence of autochthonous cutaneous leishmaniasis in northeastern Texas and southeastern Oklahoma.

Clarke CF, Bradley KK, Wright JH, Glowicz J.

Am J Trop Med Hyg. 2013 Jan;88(1):157-61. doi: 10.4269/ajtmh.2012.11-0717. Epub 2012 Nov 26.

26.

Folate status of gut microbiome affects Caenorhabditis elegans lifespan.

Nguyen TP, Clarke CF.

BMC Biol. 2012 Jul 31;10:66. doi: 10.1186/1741-7007-10-66.

27.

Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation.

Gomez F, Saiki R, Chin R, Srinivasan C, Clarke CF.

Gene. 2012 Sep 10;506(1):106-16. doi: 10.1016/j.gene.2012.06.023. Epub 2012 Jun 23.

28.

Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation.

Hill S, Lamberson CR, Xu L, To R, Tsui HS, Shmanai VV, Bekish AV, Awad AM, Marbois BN, Cantor CR, Porter NA, Clarke CF, Shchepinov MS.

Free Radic Biol Med. 2012 Aug 15;53(4):893-906. doi: 10.1016/j.freeradbiomed.2012.06.004. Epub 2012 Jun 15.

29.

Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.

Xie LX, Ozeir M, Tang JY, Chen JY, Jaquinod SK, Fontecave M, Clarke CF, Pierrel F.

J Biol Chem. 2012 Jul 6;287(28):23571-81. doi: 10.1074/jbc.M112.360354. Epub 2012 May 16.

30.

Opioid-induced hyperalgesia: a review of epidemiology, mechanisms and management.

Low Y, Clarke CF, Huh BK.

Singapore Med J. 2012 May;53(5):357-60. Review.

31.

Evaluation of New Zealand's bicycle helmet law.

Clarke CF.

N Z Med J. 2012 Feb 10;125(1349):60-9.

PMID:
22327159
32.

Measuring the neural response to continuous intramuscular infusion of hypertonic saline by perfusion MRI.

Owen DG, Clarke CF, Bureau Y, Ganapathy S, Prato FS, St Lawrence KS.

J Magn Reson Imaging. 2012 Mar;35(3):669-77. doi: 10.1002/jmri.22814. Epub 2011 Sep 23.

PMID:
21953816
33.

Coq6 hydroxylase: unmasked and bypassed.

Clarke CF.

Chem Biol. 2011 Sep 23;18(9):1069-70. doi: 10.1016/j.chembiol.2011.09.006. No abstract available.

34.

Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport.

Pfeiffer M, Kayzer EB, Yang X, Abramson E, Kenaston MA, Lago CU, Lo HH, Sedensky MM, Lunceford A, Clarke CF, Wu SJ, McLeod C, Finkel T, Morgan PG, Mills EM.

J Biol Chem. 2011 Oct 28;286(43):37712-20. doi: 10.1074/jbc.M111.271452. Epub 2011 Aug 23.

35.

Pathophysiology of the spreading of complex regional pain syndrome revisited: a case report.

Azari P, Lu Y, Clarke CF, Collins T, Briones D, Huh B.

Neuromodulation. 2011 Sep-Oct;14(5):428-31; discussion 431. doi: 10.1111/j.1525-1403.2011.00385.x. Epub 2011 Aug 19.

PMID:
21854496
36.

176th ENMC International Workshop: diagnosis and treatment of coenzyme Q₁₀ deficiency.

Rahman S, Clarke CF, Hirano M.

Neuromuscul Disord. 2012 Jan;22(1):76-86. doi: 10.1016/j.nmd.2011.05.001. Epub 2011 Jul 1. No abstract available.

37.

Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice.

Falk MJ, Polyak E, Zhang Z, Peng M, King R, Maltzman JS, Okwuego E, Horyn O, Nakamaru-Ogiso E, Ostrovsky J, Xie LX, Chen JY, Marbois B, Nissim I, Clarke CF, Gasser DL.

EMBO Mol Med. 2011 Jul;3(7):410-27. doi: 10.1002/emmm.201100149. Epub 2011 Jun 8.

38.

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.

Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F.

J Clin Invest. 2011 May;121(5):2013-24. doi: 10.1172/JCI45693. Epub 2011 Apr 11.

39.

Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutants.

Xie LX, Hsieh EJ, Watanabe S, Allan CM, Chen JY, Tran UC, Clarke CF.

Biochim Biophys Acta. 2011 May;1811(5):348-60. doi: 10.1016/j.bbalip.2011.01.009. Epub 2011 Feb 4.

40.

Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress.

Hill S, Hirano K, Shmanai VV, Marbois BN, Vidovic D, Bekish AV, Kay B, Tse V, Fine J, Clarke CF, Shchepinov MS.

Free Radic Biol Med. 2011 Jan 1;50(1):130-8. doi: 10.1016/j.freeradbiomed.2010.10.690. Epub 2010 Oct 16.

41.

para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae.

Marbois B, Xie LX, Choi S, Hirano K, Hyman K, Clarke CF.

J Biol Chem. 2010 Sep 3;285(36):27827-38. doi: 10.1074/jbc.M110.151894. Epub 2010 Jun 30.

42.

Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis.

Devarajan A, Bourquard N, Hama S, Navab M, Grijalva VR, Morvardi S, Clarke CF, Vergnes L, Reue K, Teiber JF, Reddy ST.

Antioxid Redox Signal. 2011 Feb 1;14(3):341-51. doi: 10.1089/ars.2010.3430. Epub 2010 Sep 6.

43.

Use of spinal near-infrared spectroscopy for monitoring spinal cord perfusion during endovascular thoracic aortic repairs.

Badner NH, Nicolaou G, Clarke CF, Forbes TL.

J Cardiothorac Vasc Anesth. 2011 Apr;25(2):316-9. doi: 10.1053/j.jvca.2010.01.011. Epub 2010 Mar 15. No abstract available.

PMID:
20231102
44.

Target identification using drug affinity responsive target stability (DARTS).

Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, Clarke CF, Huang J.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21984-9. doi: 10.1073/pnas.0910040106. Epub 2009 Dec 7.

45.

Evidence that ubiquinone is a required intermediate for rhodoquinone biosynthesis in Rhodospirillum rubrum.

Brajcich BC, Iarocci AL, Johnstone LA, Morgan RK, Lonjers ZT, Hotchko MJ, Muhs JD, Kieffer A, Reynolds BJ, Mandel SM, Marbois BN, Clarke CF, Shepherd JN.

J Bacteriol. 2010 Jan;192(2):436-45. doi: 10.1128/JB.01040-09. Epub 2009 Nov 20.

46.

Using perfusion MRI to measure the dynamic changes in neural activation associated with tonic muscular pain.

Owen DG, Clarke CF, Ganapathy S, Prato FS, St Lawrence KS.

Pain. 2010 Mar;148(3):375-86. doi: 10.1016/j.pain.2009.10.003. Epub 2009 Nov 14.

PMID:
19914778
47.

Genetic evidence for the requirement of the endocytic pathway in the uptake of coenzyme Q6 in Saccharomyces cerevisiae.

Padilla-López S, Jiménez-Hidalgo M, Martín-Montalvo A, Clarke CF, Navas P, Santos-Ocaña C.

Biochim Biophys Acta. 2009 Jun;1788(6):1238-48. doi: 10.1016/j.bbamem.2009.03.018. Epub 2009 Apr 2.

48.

The yeast Coq4 polypeptide organizes a mitochondrial protein complex essential for coenzyme Q biosynthesis.

Marbois B, Gin P, Gulmezian M, Clarke CF.

Biochim Biophys Acta. 2009 Jan;1791(1):69-75. doi: 10.1016/j.bbalip.2008.10.006. Epub 2008 Oct 31.

49.

Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis.

Padilla S, Tran UC, Jiménez-Hidalgo M, López-Martín JM, Martín-Montalvo A, Clarke CF, Navas P, Santos-Ocaña C.

Cell Mol Life Sci. 2009 Jan;66(1):173-86. doi: 10.1007/s00018-008-8547-7.

50.

Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2.

Saiki R, Lunceford AL, Shi Y, Marbois B, King R, Pachuski J, Kawamukai M, Gasser DL, Clarke CF.

Am J Physiol Renal Physiol. 2008 Nov;295(5):F1535-44. doi: 10.1152/ajprenal.90445.2008. Epub 2008 Sep 10.

Supplemental Content

Loading ...
Support Center