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Items: 1 to 50 of 119

1.

Cooler snakes respond more strongly to infrared stimuli, but we have no idea why.

Bakken GS, Schraft HA, Cattell RW, Tiu DB, Clark RW.

J Exp Biol. 2018 Jul 11. pii: jeb.182121. doi: 10.1242/jeb.182121. [Epub ahead of print]

PMID:
29997162
2.

Do free-ranging rattlesnakes use thermal cues to evaluate prey?

Schraft HA, Goodman C, Clark RW.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2018 Mar;204(3):295-303. doi: 10.1007/s00359-017-1239-8. Epub 2017 Dec 7.

PMID:
29218413
3.

Behavioral thermal tolerances of free-ranging rattlesnakes (Crotalus oreganus) during the summer foraging season.

Putman BJ, Clark RW.

J Therm Biol. 2017 Apr;65:8-15. doi: 10.1016/j.jtherbio.2017.01.012. Epub 2017 Jan 25.

PMID:
28343580
4.

Kangaroo rats change temperature when investigating rattlesnake predators.

Schraft HA, Clark RW.

Physiol Behav. 2017 May 1;173:174-178. doi: 10.1016/j.physbeh.2017.02.004. Epub 2017 Feb 8.

PMID:
28188761
5.

Rattlesnakes are extremely fast and variable when striking at kangaroo rats in nature: Three-dimensional high-speed kinematics at night.

Higham TE, Clark RW, Collins CE, Whitford MD, Freymiller GA.

Sci Rep. 2017 Jan 13;7:40412. doi: 10.1038/srep40412.

6.

Understanding Internal Chirality Induction of Triarylsilyl Ethers Formed from Enantiopure Alcohols.

Wang L, Zhang T, Redden BK, Sheppard CI, Clark RW, Smith MD, Wiskur SL.

J Org Chem. 2016 Sep 16;81(18):8187-93. doi: 10.1021/acs.joc.6b01137. Epub 2016 Aug 25.

PMID:
27501133
7.

Activity cycles and foraging behaviors of free-ranging sidewinder rattlesnakes (Crotalus cerastes): the ontogeny of hunting in a precocial vertebrate.

Clark RW, Dorr SW, Whitford MD, Freymiller GA, Putman BJ.

Zoology (Jena). 2016 Jun;119(3):196-206. doi: 10.1016/j.zool.2016.02.005. Epub 2016 Feb 28.

PMID:
26997261
8.

Surf and turf: predation by egg-eating snakes has led to the evolution of parental care in a terrestrial lizard.

Pike DA, Clark RW, Manica A, Tseng HY, Hsu JY, Huang WS.

Sci Rep. 2016 Feb 26;6:22207. doi: 10.1038/srep22207.

9.

Characterization of a Novel Intestinal Glycerol-3-phosphate Acyltransferase Pathway and Its Role in Lipid Homeostasis.

Khatun I, Clark RW, Vera NB, Kou K, Erion DM, Coskran T, Bobrowski WF, Okerberg C, Goodwin B.

J Biol Chem. 2016 Feb 5;291(6):2602-15. doi: 10.1074/jbc.M115.683359. Epub 2015 Dec 7.

10.

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2).

Futatsugi K, Kung DW, Orr ST, Cabral S, Hepworth D, Aspnes G, Bader S, Bian J, Boehm M, Carpino PA, Coffey SB, Dowling MS, Herr M, Jiao W, Lavergne SY, Li Q, Clark RW, Erion DM, Kou K, Lee K, Pabst BA, Perez SM, Purkal J, Jorgensen CC, Goosen TC, Gosset JR, Niosi M, Pettersen JC, Pfefferkorn JA, Ahn K, Goodwin B.

J Med Chem. 2015 Sep 24;58(18):7173-85. doi: 10.1021/acs.jmedchem.5b01006.

PMID:
26349027
11.

NFATc1 activity regulates the expression of myocilin induced by dexamethasone.

Faralli JA, Clark RW, Filla MS, Peters DM.

Exp Eye Res. 2015 Jan;130:9-16. doi: 10.1016/j.exer.2014.11.009. Epub 2014 Nov 18.

12.

Fine-scale hormonal patterns associated with birth and maternal care in the cottonmouth (Agkistrodon piscivorus), a North American pitviper snake.

Hoss SK, Garcia MJ, Earley RL, Clark RW.

Gen Comp Endocrinol. 2014 Nov 1;208:85-93. doi: 10.1016/j.ygcen.2014.08.011. Epub 2014 Aug 27.

PMID:
25169835
13.

The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats.

Erion DM, Lapworth A, Amor PA, Bai G, Vera NB, Clark RW, Yan Q, Zhu Y, Ross TT, Purkal J, Gorgoglione M, Zhang G, Bonato V, Baker L, Barucci N, D'Aquila T, Robertson A, Aiello RJ, Yan J, Trimmer J, Rolph TP, Pfefferkorn JA.

PLoS One. 2014 May 23;9(5):e97139. doi: 10.1371/journal.pone.0097139. eCollection 2014.

14.

Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity.

Cao J, Perez S, Goodwin B, Lin Q, Peng H, Qadri A, Zhou Y, Clark RW, Perreault M, Tobin JF, Gimeno RE.

Am J Physiol Endocrinol Metab. 2014 May 15;306(10):E1176-87. doi: 10.1152/ajpendo.00666.2013. Epub 2014 Apr 8.

15.

Mating systems, reproductive success, and sexual selection in secretive species: a case study of the western diamond-backed rattlesnake, Crotalus atrox.

Clark RW, Schuett GW, Repp RA, Amarello M, Smith CF, Herrmann HW.

PLoS One. 2014 Mar 5;9(3):e90616. doi: 10.1371/journal.pone.0090616. eCollection 2014.

16.

Identification of a novel, non-tetrahydroquinoline variant of the cholesteryl ester transfer protein (CETP) inhibitor torcetrapib, with improved aqueous solubility.

Kalgutkar AS, Frederick KS, Hatch HL, Ambler CM, Perry DA, Garigipati RS, Chang GC, Lefker BA, Clark RW, Morehouse LA, Francone O, Hu X.

Xenobiotica. 2014 Jul;44(7):591-605. doi: 10.3109/00498254.2013.874611. Epub 2013 Dec 31.

PMID:
24380613
17.

Silylation-based kinetic resolution of α-hydroxy lactones and lactams.

Clark RW, Deaton TM, Zhang Y, Moore MI, Wiskur SL.

Org Lett. 2013 Dec 20;15(24):6132-5. doi: 10.1021/ol402982w. Epub 2013 Dec 3.

PMID:
24299179
18.

Obesity and life expectancy among long-lived Black adults.

Singh PN, Clark RW, Herring P, Sabaté J, Shavlik D, Fraser GE.

J Gerontol A Biol Sci Med Sci. 2014 Jan;69(1):63-72. doi: 10.1093/gerona/glt049. Epub 2013 May 16.

19.

Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.

Liu S, Mistry A, Reynolds JM, Lloyd DB, Griffor MC, Perry DA, Ruggeri RB, Clark RW, Qiu X.

J Biol Chem. 2012 Oct 26;287(44):37321-9. doi: 10.1074/jbc.M112.380063. Epub 2012 Sep 7.

20.

Ground squirrel tail-flag displays alter both predatory strike and ambush site selection behaviours of rattlesnakes.

Barbour MA, Clark RW.

Proc Biol Sci. 2012 Sep 22;279(1743):3827-33. doi: 10.1098/rspb.2012.1112. Epub 2012 Jul 11.

21.

Authority figures.

Clark RW.

Hastings Cent Rep. 2012 May-Jun;42(3):5-6; author reply 6-7. No abstract available.

PMID:
22670288
22.

Cryptic sociality in rattlesnakes (Crotalus horridus) detected by kinship analysis.

Clark RW, Brown WS, Stechert R, Greene HW.

Biol Lett. 2012 Aug 23;8(4):523-5. doi: 10.1098/rsbl.2011.1217. Epub 2012 Feb 22.

23.

Dexamethasone-associated cross-linked actin network formation in human trabecular meshwork cells involves β3 integrin signaling.

Filla MS, Schwinn MK, Nosie AK, Clark RW, Peters DM.

Invest Ophthalmol Vis Sci. 2011 May 5;52(6):2952-9. doi: 10.1167/iovs.10-6618.

24.

Roads, interrupted dispersal, and genetic diversity in timber rattlesnakes.

Clark RW, Brown WS, Stechert R, Zamudio KR.

Conserv Biol. 2010 Aug;24(4):1059-69. doi: 10.1111/j.1523-1739.2009.01439.x. Epub 2010 Feb 11.

PMID:
20151984
25.

Assessment of cholesteryl ester transfer protein inhibitors for interaction with proteins involved in the immune response to infection.

Clark RW, Cunningham D, Cong Y, Subashi TA, Tkalcevic GT, Lloyd DB, Boyd JG, Chrunyk BA, Karam GA, Qiu X, Wang IK, Francone OL.

J Lipid Res. 2010 May;51(5):967-74. doi: 10.1194/jlr.M002295. Epub 2009 Oct 21.

26.

Guanidine hydrochloride-induced unfolding of the three heme coordination states of the CO-sensing transcription factor, CooA.

Lee AJ, Clark RW, Youn H, Ponter S, Burstyn JN.

Biochemistry. 2009 Jul 21;48(28):6585-97. doi: 10.1021/bi801827j.

27.

Pharmacokinetic, pharmacodynamic, and safety profile of a new cholesteryl ester transfer protein inhibitor in healthy human subjects.

Wolk R, Chen D, Clark RW, Mancuso J, Barclay PL.

Clin Pharmacol Ther. 2009 Oct;86(4):430-7. doi: 10.1038/clpt.2009.120. Epub 2009 Jul 8.

PMID:
19587642
28.

Silica-bound copper(II)triazacyclononane as a phosphate esterase: effect of linker length and surface hydrophobicity.

Bodsgard BR, Clark RW, Ehrbar AW, Burstyn JN.

Dalton Trans. 2009 Apr 7;(13):2365-73. doi: 10.1039/b811398j. Epub 2009 Feb 9.

PMID:
19290370
29.

Multicolor, time-gated, soft x-ray pinhole imaging of wire array and gas puff Z pinches on the Z and Saturn pulsed power generators.

Jones B, Coverdale CA, Nielsen DS, Jones MC, Deeney C, Serrano JD, Nielsen-Weber LB, Meyer CJ, Apruzese JP, Clark RW, Coleman PL.

Rev Sci Instrum. 2008 Oct;79(10):10E906. doi: 10.1063/1.2969280.

PMID:
19044561
30.

Integrating individual behaviour and landscape genetics: the population structure of timber rattlesnake hibernacula.

Clark RW, Brown WS, Stechert R, Zamudio KR.

Mol Ecol. 2008 Feb;17(3):719-30. Epub 2007 Nov 19.

PMID:
18028304
31.

Students unite to create State of the Planet course.

Rypien KL, Anderson J, Andras J, Clark RW, Gerrish GA, Mandel JT, Nydam ML, Riskin DK.

Nature. 2007 Jun 14;447(7146):775. No abstract available.

PMID:
17568725
32.

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.

Qiu X, Mistry A, Ammirati MJ, Chrunyk BA, Clark RW, Cong Y, Culp JS, Danley DE, Freeman TB, Geoghegan KF, Griffor MC, Hawrylik SJ, Hayward CM, Hensley P, Hoth LR, Karam GA, Lira ME, Lloyd DB, McGrath KM, Stutzman-Engwall KJ, Subashi AK, Subashi TA, Thompson JF, Wang IK, Zhao H, Seddon AP.

Nat Struct Mol Biol. 2007 Feb;14(2):106-13. Epub 2007 Jan 21.

PMID:
17237796
33.

DNA binding by an imidazole-sensing CooA variant is dependent on the heme redox state.

Clark RW, Youn H, Lee AJ, Roberts GP, Burstyn JN.

J Biol Inorg Chem. 2007 Feb;12(2):139-46. Epub 2006 Nov 3.

PMID:
17082920
34.

Modeling proline ligation in the heme-dependent CO sensor, CooA, using small-molecule analogs.

Pinkert JC, Clark RW, Burstyn JN.

J Biol Inorg Chem. 2006 Jul;11(5):642-50. Epub 2006 May 25.

PMID:
16724227
35.

Raising high-density lipoprotein with cholesteryl ester transfer protein inhibitors.

Clark RW.

Curr Opin Pharmacol. 2006 Apr;6(2):162-8. Epub 2006 Feb 17. Review.

PMID:
16487747
36.

Unexpected NO-dependent DNA binding by the CooA homolog from Carboxydothermus hydrogenoformans.

Clark RW, Lanz ND, Lee AJ, Kerby RL, Roberts GP, Burstyn JN.

Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):891-6. Epub 2006 Jan 12.

37.

Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of action.

Clark RW, Ruggeri RB, Cunningham D, Bamberger MJ.

J Lipid Res. 2006 Mar;47(3):537-52. Epub 2005 Dec 2.

38.

Modeling of clusters in a strong 248-nm laser field by a three-dimensional relativistic molecular dynamic model.

Petrov GM, Davis J, Velikovich AL, Kepple PC, Dasgupta A, Clark RW, Borisov AB, Boyer K, Rhodes CK.

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Mar;71(3 Pt 2B):036411. Epub 2005 Mar 25.

PMID:
15903592
39.

The redox behavior of the heme in cystathionine beta-synthase is sensitive to pH.

Pazicni S, Lukat-Rodgers GS, Oliveriusová J, Rees KA, Parks RB, Clark RW, Rodgers KR, Kraus JP, Burstyn JN.

Biochemistry. 2004 Nov 23;43(46):14684-95.

PMID:
15544339
40.

Investigation of the role of the N-terminal proline, the distal heme ligand in the CO sensor CooA.

Clark RW, Youn H, Parks RB, Cherney MM, Roberts GP, Burstyn JN.

Biochemistry. 2004 Nov 9;43(44):14149-60.

PMID:
15518565
41.

Kin recognition in rattlesnakes.

Clark RW.

Proc Biol Sci. 2004 May 7;271 Suppl 4:S243-5.

42.
43.

Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol.

Brousseau ME, Schaefer EJ, Wolfe ML, Bloedon LT, Digenio AG, Clark RW, Mancuso JP, Rader DJ.

N Engl J Med. 2004 Apr 8;350(15):1505-15.

44.

Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib.

Clark RW, Sutfin TA, Ruggeri RB, Willauer AT, Sugarman ED, Magnus-Aryitey G, Cosgrove PG, Sand TM, Wester RT, Williams JA, Perlman ME, Bamberger MJ.

Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):490-7. Epub 2004 Jan 22.

45.

A comparison of the ring conformational properties of two derivatives prepared from the same diene diacetate precursor.

Guzei IA, Clark RW, Burke SD, Lambert WT.

Acta Crystallogr C. 2003 Dec;59(Pt 12):o721-3. Epub 2003 Nov 30.

PMID:
14671382
46.

Polymorphisms in the CETP gene and association with CETP mass and HDL levels.

Thompson JF, Lira ME, Durham LK, Clark RW, Bamberger MJ, Milos PM.

Atherosclerosis. 2003 Apr;167(2):195-204.

PMID:
12818401
47.

A 1,2,4-diazaphospholane complex of rhodium.

Clark RW, Guzei IA, Jin WC, Landis CR.

Acta Crystallogr C. 2003 Apr;59(Pt 4):M144-5. Epub 2003 Mar 21.

PMID:
12682395
48.

"Inverse-electron-demand" ligand substitution in palladium(0)-olefin complexes.

Stahl SS, Thorman JL, de Silva N, Guzei IA, Clark RW.

J Am Chem Soc. 2003 Jan 8;125(1):12-3.

PMID:
12515487
49.

Chemistry of the aromatic 9-germafluorenyl dianion and some related silicon and carbon species.

Liu Y, Ballweg D, Müller T, Guzei IA, Clark RW, West R.

J Am Chem Soc. 2002 Oct 16;124(41):12174-81.

PMID:
12371857
50.

Analysis of the L116K variant of CooA, the heme-containing CO sensor, suggests the presence of an unusual heme ligand resulting in novel activity.

Youn H, Kerby RL, Thorsteinsson MV, Clark RW, Burstyn JN, Roberts GP.

J Biol Chem. 2002 Sep 13;277(37):33616-23. Epub 2002 Jul 16.

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