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Items: 1 to 50 of 117

1.

Whole genome sequencing and rare variant analysis in essential tremor families.

Odgerel Z, Sonti S, Hernandez N, Park J, Ottman R, Louis ED, Clark LN.

PLoS One. 2019 Aug 12;14(8):e0220512. doi: 10.1371/journal.pone.0220512. eCollection 2019.

2.

Current Opinions and Consensus for Studying Tremor in Animal Models.

Kuo SH, Louis ED, Faust PL, Handforth A, Chang SY, Avlar B, Lang EJ, Pan MK, Miterko LN, Brown AM, Sillitoe RV, Anderson CJ, Pulst SM, Gallagher MJ, Lyman KA, Chetkovich DM, Clark LN, Tio M, Tan EK, Elble RJ.

Cerebellum. 2019 May 23. doi: 10.1007/s12311-019-01037-1. [Epub ahead of print]

PMID:
31124049
3.

Practice patterns regarding post-discharge chemoprophylaxis for venous thromboembolism following bariatric surgery in the United States.

Clark LN, Helm MC, Gould JC.

Surg Obes Relat Dis. 2019 May;15(5):703-707. doi: 10.1016/j.soard.2019.02.017. Epub 2019 Mar 20.

PMID:
31005460
4.

Copy number variation of LINGO1 in familial dystonic tremor.

Alakbarzade V, Iype T, Chioza BA, Singh R, Harlalka GV, Hardy H, Sreekantan-Nair A, Proukakis C, Peall K, Clark LN, Caswell R, Lango Allen H, Wakeling M, Chilton JK, Baple EL, Louis ED, Warner TT, Crosby AH.

Neurol Genet. 2019 Feb 4;5(1):e307. doi: 10.1212/NXG.0000000000000307. eCollection 2019 Feb.

5.

SMPD1 mutations, activity, and α-synuclein accumulation in Parkinson's disease.

Alcalay RN, Mallett V, Vanderperre B, Tavassoly O, Dauvilliers Y, Wu RYJ, Ruskey JA, Leblond CS, Ambalavanan A, Laurent SB, Spiegelman D, Dionne-Laporte A, Liong C, Levy OA, Fahn S, Waters C, Kuo SH, Chung WK, Ford B, Marder KS, Kang UJ, Hassin-Baer S, Greenbaum L, Trempe JF, Wolf P, Oliva P, Zhang XK, Clark LN, Langlois M, Dion PA, Fon EA, Dupre N, Rouleau GA, Gan-Or Z.

Mov Disord. 2019 Apr;34(4):526-535. doi: 10.1002/mds.27642. Epub 2019 Feb 20.

PMID:
30788890
6.

Very Early Versus Early Readmissions in General Surgery Patients.

Clark LN, Helm MC, Singh S, Gould JC.

J Surg Res. 2018 Dec;232:524-530. doi: 10.1016/j.jss.2018.07.029. Epub 2018 Aug 3.

PMID:
30463768
7.

Validity of probands' reports and self-reports of essential tremor: Data from a large family study in North America.

Louis ED, Hernandez N, Sebastian AA, Clark LN, Ottman R.

J Neurol Sci. 2018 Oct 15;393:45-50. doi: 10.1016/j.jns.2018.08.006. Epub 2018 Aug 6.

PMID:
30103063
8.

Transient, Isolated Head Tremor in "Unaffected" Individuals: Is Essential Tremor an Even More Prevalent Disease Than We Suppose?

Louis ED, Meyers JH, Cristal AD, Patel A, Tinaz S, Pullman SL, Clark LN, Ottman R, Factor-Litvak P.

Front Neurol. 2018 Jul 13;9:570. doi: 10.3389/fneur.2018.00570. eCollection 2018.

9.

The impact of preoperative anemia and malnutrition on outcomes in paraesophageal hernia repair.

Clark LN, Helm MC, Higgins R, Lak K, Kastenmeier A, Kindel T, Goldblatt M, Gould JC.

Surg Endosc. 2018 Nov;32(11):4666-4672. doi: 10.1007/s00464-018-6311-0. Epub 2018 Jun 22.

PMID:
29934871
10.

A Drosophila Model of Essential Tremor.

Smith P, Arias R, Sonti S, Odgerel Z, Santa-Maria I, McCabe BD, Tsaneva-Atanasova K, Louis ED, Hodge JJL, Clark LN.

Sci Rep. 2018 May 16;8(1):7664. doi: 10.1038/s41598-018-25949-w.

11.

High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation.

Lencz T, Yu J, Palmer C, Carmi S, Ben-Avraham D, Barzilai N, Bressman S, Darvasi A, Cho JH, Clark LN, Gümüş ZH, Joseph V, Klein R, Lipkin S, Offit K, Ostrer H, Ozelius LJ, Peter I, Atzmon G, Pe'er I.

Hum Genet. 2018 Apr;137(4):343-355. doi: 10.1007/s00439-018-1886-z. Epub 2018 Apr 28.

PMID:
29705978
12.

Genetic Testing Preferences of Individuals in Families with Essential Tremor.

Naranjo KV, Park J, Chen KP, Hernandez N, Clark LN, Ottman R, Louis ED.

Tremor Other Hyperkinet Mov (N Y). 2018 Mar 27;8:545. doi: 10.7916/D8B296RK. eCollection 2018.

13.

Knowledge about Essential Tremor: A Study of Essential Tremor Families.

Cristal AD, Chen KP, Hernandez NC, Factor-Litvak P, Clark LN, Ottman R, Louis ED.

Front Neurol. 2018 Jan 26;9:27. doi: 10.3389/fneur.2018.00027. eCollection 2018.

14.

Essential tremor.

Clark LN, Louis ED.

Handb Clin Neurol. 2018;147:229-239. doi: 10.1016/B978-0-444-63233-3.00015-4. Review.

15.

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease.

Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, Chuang LS, Carmi S, Villaverde N, Li X, Rivas M, Levine AP, Bao X, Labrias PR, Haritunians T, Ruane D, Gettler K, Chen E, Li D, Schiff ER, Pontikos N, Barzilai N, Brant SR, Bressman S, Cheifetz AS, Clark LN, Daly MJ, Desnick RJ, Duerr RH, Katz S, Lencz T, Myers RH, Ostrer H, Ozelius L, Payami H, Peter Y, Rioux JD, Segal AW, Scott WK, Silverberg MS, Vance JM, Ubarretxena-Belandia I, Foroud T, Atzmon G, Pe'er I, Ioannou Y, McGovern DPB, Yue Z, Schadt EE, Cho JH, Peter I.

Sci Transl Med. 2018 Jan 10;10(423). pii: eaai7795. doi: 10.1126/scitranslmed.aai7795.

16.

Candidate gene analysis for Alzheimer's disease in adults with Down syndrome.

Lee JH, Lee AJ, Dang LH, Pang D, Kisselev S, Krinsky-McHale SJ, Zigman WB, Luchsinger JA, Silverman W, Tycko B, Clark LN, Schupf N.

Neurobiol Aging. 2017 Aug;56:150-158. doi: 10.1016/j.neurobiolaging.2017.04.018. Epub 2017 May 3.

17.

Action Tremor Asymmetry Profile Does Not Aggregate in Families with Essential Tremor.

Louis ED, Hernandez N, Chen KP, Naranjo KV, Park J, Clark LN, Ottman R.

Front Neurol. 2017 Apr 19;8:148. doi: 10.3389/fneur.2017.00148. eCollection 2017.

18.

Early Head Tremor in Essential Tremor: A Case Series and Commentary.

Louis ED, Badejo FM, Cristal AD, Meyers J, Hernandez N, Chen KP, Naranjo KV, Park J, Clark LN.

Tremor Other Hyperkinet Mov (N Y). 2017 Mar 25;7:453. doi: 10.7916/D8KW5MRG. eCollection 2017.

19.

Familial Aggregation of the Cerebellar Signs in Familial Essential Tremor.

Louis ED, Hernandez N, Chen KP, Naranjo KV, Park J, Clark LN, Ottman R.

Tremor Other Hyperkinet Mov (N Y). 2017 Jan 13;7:439. doi: 10.7916/D8KK9C8Q. eCollection 2017.

20.

Usability evaluation of an emergency department information system prototype designed using cognitive systems engineering techniques.

Clark LN, Benda NC, Hegde S, McGeorge NM, Guarrera-Schick TK, Hettinger AZ, LaVergne DT, Perry SJ, Wears RL, Fairbanks RJ, Bisantz AM.

Appl Ergon. 2017 Apr;60:356-365. doi: 10.1016/j.apergo.2016.12.018. Epub 2017 Jan 3.

21.

Assessment of Innovative Emergency Department Information Displays in a Clinical Simulation Center.

McGeorge N, Hegde S, Berg RL, Guarrera-Schick TK, LaVergne DT, Casucci SN, Hettinger AZ, Clark LN, Lin L, Fairbanks RJ, Benda NC, Sun L, Wears RL, Perry S, Bisantz A.

J Cogn Eng Decis Mak. 2015 Dec;9(4):329-346.

22.

Genome-wide association study in essential tremor identifies three new loci.

Müller SH, Girard SL, Hopfner F, Merner ND, Bourassa CV, Lorenz D, Clark LN, Tittmann L, Soto-Ortolaza AI, Klebe S, Hallett M, Schneider SA, Hodgkinson CA, Lieb W, Wszolek ZK, Pendziwiat M, Lorenzo-Betancor O, Poewe W, Ortega-Cubero S, Seppi K, Rajput A, Hussl A, Rajput AH, Berg D, Dion PA, Wurster I, Shulman JM, Srulijes K, Haubenberger D, Pastor P, Vilariño-Güell C, Postuma RB, Bernard G, Ladwig KH, Dupré N, Jankovic J, Strauch K, Panisset M, Winkelmann J, Testa CM, Reischl E, Zeuner KE, Ross OA, Arzberger T, Chouinard S, Deuschl G, Louis ED, Kuhlenbäumer G, Rouleau GA.

Brain. 2016 Dec;139(Pt 12):3163-3169. Epub 2016 Oct 20.

23.

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, Holstege H, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Barber I, Braae A, Brown K, Morgan K, Maetzler W, Berg D, Troakes C, Al-Sarraj S, Lashley T, Holton J, Compta Y, Van Deerlin V, Trojanowski JQ, Serrano GE, Beach TG, Clarimon J, Lleó A, Morenas-Rodríguez E, Lesage S, Galasko D, Masliah E, Santana I, Diez M, Pastor P, Tienari PJ, Myllykangas L, Oinas M, Revesz T, Lees A, Boeve BF, Petersen RC, Ferman TJ, Escott-Price V, Graff-Radford N, Cairns NJ, Morris JC, Stone DJ, Pickering-Brown S, Mann D, Dickson DW, Halliday GM, Singleton A, Guerreiro R, Bras J.

Neurobiol Aging. 2017 Jan;49:214.e13-214.e15. doi: 10.1016/j.neurobiolaging.2016.08.023. Epub 2016 Sep 2.

24.

NT1014, a novel biguanide, inhibits ovarian cancer growth in vitro and in vivo.

Zhang L, Han J, Jackson AL, Clark LN, Kilgore J, Guo H, Livingston N, Batchelor K, Yin Y, Gilliam TP, Gehrig PA, Sheng X, Zhou C, Bae-Jump VL.

J Hematol Oncol. 2016 Sep 21;9(1):91.

25.

Nuclear factor XIIIa staining (clone AC-1A1 mouse monoclonal) is a highly sensitive marker of sebaceous differentiation in normal and neoplastic sebocytes.

Clark LN, Elwood HR, Uhlenhake EE, Smoller BR, Shalin SC, Gardner JM.

J Cutan Pathol. 2016 Aug;43(8):657-62. doi: 10.1111/cup.12727. Epub 2016 Jun 14.

PMID:
27153463
26.

Nuclear factor XIIIa staining (clone AC-1A1 mouse monoclonal) is a sensitive and specific marker to discriminate sebaceous proliferations from other cutaneous clear cell neoplasms.

Uhlenhake EE, Clark LN, Smoller BR, Shalin SC, Gardner JM.

J Cutan Pathol. 2016 Aug;43(8):649-56. doi: 10.1111/cup.12726. Epub 2016 Jun 10.

PMID:
27153339
27.

The effect of MAPT haplotype on neocortical Lewy body pathology in Parkinson disease.

Robakis D, Cortes E, Clark LN, Vonsattel JP, Virmani T, Alcalay RN, Crary JF, Levy OA.

J Neural Transm (Vienna). 2016 Jun;123(6):583-8. doi: 10.1007/s00702-016-1552-3. Epub 2016 Apr 20.

28.

A mutation abolishing the ZMPSTE24 cleavage site in prelamin A causes a progeroid disorder.

Wang Y, Lichter-Konecki U, Anyane-Yeboa K, Shaw JE, Lu JT, Östlund C, Shin JY, Clark LN, Gundersen GG, Nagy PL, Worman HJ.

J Cell Sci. 2016 May 15;129(10):1975-80. doi: 10.1242/jcs.187302. Epub 2016 Mar 31.

29.

Identification of candidate genes for familial early-onset essential tremor.

Liu X, Hernandez N, Kisselev S, Floratos A, Sawle A, Ionita-Laza I, Ottman R, Louis ED, Clark LN.

Eur J Hum Genet. 2016 Jul;24(7):1009-15. doi: 10.1038/ejhg.2015.228. Epub 2015 Oct 28.

30.

Genetic analysis of ten common degenerative hereditary ataxia loci in patients with essential tremor.

Clark LN, Ye X, Liu X, Mirzozoda K, Louis ED.

Parkinsonism Relat Disord. 2015 Aug;21(8):943-7. doi: 10.1016/j.parkreldis.2015.06.004. Epub 2015 Jun 6.

31.

Challenges in essential tremor genetics.

Clark LN, Louis ED.

Rev Neurol (Paris). 2015 Jun-Jul;171(6-7):466-74. doi: 10.1016/j.neurol.2015.02.015. Epub 2015 May 21. Review.

32.

Familial versus Sporadic Essential Tremor: What Patterns Can One Decipher in Age of Onset?

Louis ED, Clark LN, Ottman R.

Neuroepidemiology. 2015;44(3):166-72. doi: 10.1159/000381807. Epub 2015 May 7.

33.

Gene-wise association of variants in four lysosomal storage disorder genes in neuropathologically confirmed Lewy body disease.

Clark LN, Chan R, Cheng R, Liu X, Park N, Parmalee N, Kisselev S, Cortes E, Torres PA, Pastores GM, Vonsattel JP, Alcalay R, Marder K, Honig LL, Fahn S, Mayeux R, Shelanski M, Di Paolo G, Lee JH.

PLoS One. 2015 May 1;10(5):e0125204. doi: 10.1371/journal.pone.0125204. eCollection 2015.

34.
35.

Genetic analysis of FMR1 repeat expansion in essential tremor.

Clark LN, Ye X, Liu X, Louis ED.

Neurosci Lett. 2015 Apr 23;593:114-7. doi: 10.1016/j.neulet.2015.03.027. Epub 2015 Mar 18.

36.

Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau.

Santa-Maria I, Alaniz ME, Renwick N, Cela C, Fulga TA, Van Vactor D, Tuschl T, Clark LN, Shelanski ML, McCabe BD, Crary JF.

J Clin Invest. 2015 Feb;125(2):681-6. doi: 10.1172/JCI78421. Epub 2015 Jan 9.

37.

NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases.

Nalls MA, Bras J, Hernandez DG, Keller MF, Majounie E, Renton AE, Saad M, Jansen I, Guerreiro R, Lubbe S, Plagnol V, Gibbs JR, Schulte C, Pankratz N, Sutherland M, Bertram L, Lill CM, DeStefano AL, Faroud T, Eriksson N, Tung JY, Edsall C, Nichols N, Brooks J, Arepalli S, Pliner H, Letson C, Heutink P, Martinez M, Gasser T, Traynor BJ, Wood N, Hardy J, Singleton AB; International Parkinson's Disease Genomics Consortium (IPDGC); Parkinson's Disease meta-analysis consortium.

Neurobiol Aging. 2015 Mar;36(3):1605.e7-12. doi: 10.1016/j.neurobiolaging.2014.07.028. Epub 2014 Aug 4.

38.

Clinical correlations with Lewy body pathology in LRRK2-related Parkinson disease.

Kalia LV, Lang AE, Hazrati LN, Fujioka S, Wszolek ZK, Dickson DW, Ross OA, Van Deerlin VM, Trojanowski JQ, Hurtig HI, Alcalay RN, Marder KS, Clark LN, Gaig C, Tolosa E, Ruiz-Martínez J, Marti-Masso JF, Ferrer I, López de Munain A, Goldman SM, Schüle B, Langston JW, Aasly JO, Giordana MT, Bonifati V, Puschmann A, Canesi M, Pezzoli G, Maues De Paula A, Hasegawa K, Duyckaerts C, Brice A, Stoessl AJ, Marras C.

JAMA Neurol. 2015 Jan;72(1):100-5. doi: 10.1001/jamaneurol.2014.2704.

39.

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study.

Sharp ME, Caccappolo E, Mejia-Santana H, Tang MX, Rosado L, Orbe Reilly M, Ruiz D, Louis ED, Comella C, Nance M, Bressman S, Scott WK, Tanner C, Waters C, Fahn S, Cote L, Ford B, Rezak M, Novak K, Friedman JH, Pfeiffer R, Payami H, Molho E, Factor SA, Nutt J, Serrano C, Arroyo M, Pauciulo MW, Nichols WC, Clark LN, Alcalay RN, Marder KS.

Mov Disord. 2015 Feb;30(2):278-83. doi: 10.1002/mds.26065. Epub 2014 Nov 12.

40.

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins.

Carmi S, Hui KY, Kochav E, Liu X, Xue J, Grady F, Guha S, Upadhyay K, Ben-Avraham D, Mukherjee S, Bowen BM, Thomas T, Vijai J, Cruts M, Froyen G, Lambrechts D, Plaisance S, Van Broeckhoven C, Van Damme P, Van Marck H, Barzilai N, Darvasi A, Offit K, Bressman S, Ozelius LJ, Peter I, Cho JH, Ostrer H, Atzmon G, Clark LN, Lencz T, Pe'er I.

Nat Commun. 2014 Sep 9;5:4835. doi: 10.1038/ncomms5835.

41.

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.

Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, DeStefano AL, Kara E, Bras J, Sharma M, Schulte C, Keller MF, Arepalli S, Letson C, Edsall C, Stefansson H, Liu X, Pliner H, Lee JH, Cheng R; International Parkinson's Disease Genomics Consortium (IPDGC); Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI); 23andMe; GenePD; NeuroGenetics Research Consortium (NGRC); Hussman Institute of Human Genomics (HIHG); Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE); North American Brain Expression Consortium (NABEC); United Kingdom Brain Expression Consortium (UKBEC); Greek Parkinson's Disease Consortium; Alzheimer Genetic Analysis Group, Ikram MA, Ioannidis JP, Hadjigeorgiou GM, Bis JC, Martinez M, Perlmutter JS, Goate A, Marder K, Fiske B, Sutherland M, Xiromerisiou G, Myers RH, Clark LN, Stefansson K, Hardy JA, Heutink P, Chen H, Wood NW, Houlden H, Payami H, Brice A, Scott WK, Gasser T, Bertram L, Eriksson N, Foroud T, Singleton AB.

Nat Genet. 2014 Sep;46(9):989-93. doi: 10.1038/ng.3043. Epub 2014 Jul 27.

42.

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

Bras J, Guerreiro R, Darwent L, Parkkinen L, Ansorge O, Escott-Price V, Hernandez DG, Nalls MA, Clark LN, Honig LS, Marder K, Van Der Flier WM, Lemstra A, Scheltens P, Rogaeva E, St George-Hyslop P, Londos E, Zetterberg H, Ortega-Cubero S, Pastor P, Ferman TJ, Graff-Radford NR, Ross OA, Barber I, Braae A, Brown K, Morgan K, Maetzler W, Berg D, Troakes C, Al-Sarraj S, Lashley T, Compta Y, Revesz T, Lees A, Cairns N, Halliday GM, Mann D, Pickering-Brown S, Dickson DW, Singleton A, Hardy J.

Hum Mol Genet. 2014 Dec 1;23(23):6139-46. doi: 10.1093/hmg/ddu334. Epub 2014 Jun 27.

43.

Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.

Vacic V, Ozelius LJ, Clark LN, Bar-Shira A, Gana-Weisz M, Gurevich T, Gusev A, Kedmi M, Kenny EE, Liu X, Mejia-Santana H, Mirelman A, Raymond D, Saunders-Pullman R, Desnick RJ, Atzmon G, Burns ER, Ostrer H, Hakonarson H, Bergman A, Barzilai N, Darvasi A, Peter I, Guha S, Lencz T, Giladi N, Marder K, Pe'er I, Bressman SB, Orr-Urtreger A.

Hum Mol Genet. 2014 Sep 1;23(17):4693-702. doi: 10.1093/hmg/ddu158. Epub 2014 May 19.

44.

Estrogen receptor α variants affect age at onset of Alzheimer's disease in a multiethnic female cohort.

Janicki SC, Park N, Cheng R, Clark LN, Lee JH, Schupf N.

Dement Geriatr Cogn Disord. 2014;38(3-4):200-13. doi: 10.1159/000355559. Epub 2014 Apr 8.

45.

Clinical classification of borderline cases in the family study of essential tremor: an analysis of phenotypic features.

Louis ED, Ottman R, Clark LN.

Tremor Other Hyperkinet Mov (N Y). 2014 Feb 10;4:220. doi: 10.7916/D8CF9N23. eCollection 2014.

46.

Essential Tremor in a Charcot-Marie-Tooth Type 2C Kindred Does Not Segregate with the TRPV4 R269H Mutation.

Louis ED, Hernandez N, Ottman R, Ionita-Laza I, Clark LN.

Case Rep Neurol. 2014 Jan 22;6(1):1-6. doi: 10.1159/000357665. eCollection 2014 Jan.

47.

The spiral axis as a clinical tool to distinguish essential tremor from dystonia cases.

Michalec M, Hernandez N, Clark LN, Louis ED.

Parkinsonism Relat Disord. 2014 May;20(5):541-4. doi: 10.1016/j.parkreldis.2014.01.021. Epub 2014 Feb 7.

48.

Parkinson's disease with Lewy bodies associated with a heterozygous PARKIN dosage mutation.

Sharp ME, Marder KS, Côté L, Clark LN, Nichols WC, Vonsattel JP, Alcalay RN.

Mov Disord. 2014 Apr;29(4):566-8. doi: 10.1002/mds.25792. Epub 2013 Dec 27.

49.

The microtubule associated protein tau H1 haplotype and risk of essential tremor.

Clark LN, Liu X, Parmalee NL, Hernandez N, Louis ED.

Eur J Neurol. 2014 Jul;21(7):1044-8. doi: 10.1111/ene.12335. Epub 2013 Dec 26.

50.

Estrogen receptor β variants modify risk for Alzheimer's disease in a multiethnic female cohort.

Janicki SC, Park N, Cheng R, Lee JH, Schupf N, Clark LN.

J Alzheimers Dis. 2014;40(1):83-93. doi: 10.3233/JAD-130551.

PMID:
24326520

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