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Items: 1 to 50 of 105

1.

Novel zebrafish behavioral assay to identify modifiers of the rapid, nongenomic stress response.

Lee HB, Schwab TL, Sigafoos AN, Gauerke JL, Krug RG 2nd, Serres MR, Jacobs DC, Cotter RP, Das B, Petersen MO, Daby CL, Urban RM, Berry BC, Clark KJ.

Genes Brain Behav. 2018 Dec 26:e12549. doi: 10.1111/gbb.12549. [Epub ahead of print]

PMID:
30588759
2.

PCNT point mutations and familial intracranial aneurysms.

Lorenzo-Betancor O, Blackburn PR, Edwards E, Vázquez-do-Campo R, Klee EW, Labbé C, Hodges K, Glover P, Sigafoos AN, Soto AI, Walton RL, Doxsey S, Bober MB, Jennings S, Clark KJ, Asmann Y, Miller D, Freeman WD, Meschia J, Ross OA.

Neurology. 2018 Dec 4;91(23):e2170-e2181. doi: 10.1212/WNL.0000000000006614. Epub 2018 Nov 9.

PMID:
30413633
3.

Abnormal Locus Coeruleus Sleep Activity Alters Sleep Signatures of Memory Consolidation and Impairs Place Cell Stability and Spatial Memory.

Swift KM, Gross BA, Frazer MA, Bauer DS, Clark KJD, Vazey EM, Aston-Jones G, Li Y, Pickering AE, Sara SJ, Poe GR.

Curr Biol. 2018 Nov 19;28(22):3599-3609.e4. doi: 10.1016/j.cub.2018.09.054. Epub 2018 Nov 1.

PMID:
30393040
4.

Robust activation of microhomology-mediated end joining for precision gene editing applications.

Ata H, Ekstrom TL, Martínez-Gálvez G, Mann CM, Dvornikov AV, Schaefbauer KJ, Ma AC, Dobbs D, Clark KJ, Ekker SC.

PLoS Genet. 2018 Sep 12;14(9):e1007652. doi: 10.1371/journal.pgen.1007652. eCollection 2018 Sep.

5.

Utility of DNA, RNA, Protein, and Functional Approaches to Solve Cryptic Immunodeficiencies.

Cousin MA, Smith MJ, Sigafoos AN, Jin JJ, Murphree MI, Boczek NJ, Blackburn PR, Oliver GR, Aleff RA, Clark KJ, Wieben ED, Joshi AY, Pichurin PN, Abraham RS, Klee EW.

J Clin Immunol. 2018 Apr;38(3):307-319. doi: 10.1007/s10875-018-0499-6. Epub 2018 Apr 18.

PMID:
29671115
6.

Bacterial gene control by DNA looping using engineered dimeric transcription activator like effector (TALE) proteins.

Becker NA, Schwab TL, Clark KJ, Maher LJ 3rd.

Nucleic Acids Res. 2018 Mar 16;46(5):2690-2696. doi: 10.1093/nar/gky047.

7.

The endocannabinoid gene faah2a modulates stress-associated behavior in zebrafish.

Krug RG 2nd, Lee HB, El Khoury LY, Sigafoos AN, Petersen MO, Clark KJ.

PLoS One. 2018 Jan 5;13(1):e0190897. doi: 10.1371/journal.pone.0190897. eCollection 2018.

8.

Kinetics of Plasma Cell-Free DNA and Creatine Kinase in a Canine Model of Tissue Injury.

Wilson IJ, Burchell RK, Worth AJ, Burton SE, Gedye KR, Clark KJ, Crosse KR, Jack M, Odom TF, De Grey SJ, McGlade KMS, Tomlin SC, Lopez-Villalobos N, Gal A.

J Vet Intern Med. 2018 Jan;32(1):157-164. doi: 10.1111/jvim.14901. Epub 2017 Dec 12.

9.

Intestinal Transit Time and Cortisol-Mediated Stress in Zebrafish.

Brady C, Denora M, Shannon I, Clark KJ, Rich A.

Zebrafish. 2017 Oct;14(5):404-410. doi: 10.1089/zeb.2017.1440. Epub 2017 Jul 20.

10.

Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly.

El-Rass S, Eisa-Beygi S, Khong E, Brand-Arzamendi K, Mauro A, Zhang H, Clark KJ, Ekker SC, Wen XY.

Biol Open. 2017 Mar 15;6(3):348-357. doi: 10.1242/bio.021212.

11.

Forward Genetic Screening Using Behavioral Tests in Zebrafish: A Proof of Concept Analysis of Mutants.

Gerlai R, Poshusta TL, Rampersad M, Fernandes Y, Greenwood TM, Cousin MA, Klee EW, Clark KJ.

Behav Genet. 2017 Jan;47(1):125-139. doi: 10.1007/s10519-016-9818-y. Epub 2016 Oct 5.

PMID:
27704300
12.

Functional characterization of a GFAP variant of uncertain significance in an Alexander disease case within the setting of an individualized medicine clinic.

Boczek NJ, Sigafoos AN, Zimmermann MT, Maus RL, Cousin MA, Blackburn PR, Urrutia R, Clark KJ, Patterson MC, Wick MJ, Klee EW.

Clin Case Rep. 2016 Aug 15;4(9):885-95. doi: 10.1002/ccr3.655. eCollection 2016 Sep.

13.

The zebrafish genome editing toolkit.

Ata H, Clark KJ, Ekker SC.

Methods Cell Biol. 2016;135:149-70. doi: 10.1016/bs.mcb.2016.04.023. Epub 2016 May 30.

PMID:
27443924
14.

Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated with Liver Cirrhosis and Hepatocellular Carcinoma.

Blackburn PR, Hickey RD, Nace RA, Giama NH, Kraft DL, Bordner AJ, Chaiteerakij R, McCormick JB, Radulovic M, Graham RP, Torbenson MS, Tortorelli S, Scott CR, Lindor NM, Milliner DS, Oglesbee D, Al-Qabandi W, Grompe M, Gavrilov DK, El-Youssef M, Clark KJ, Atwal PS, Roberts LR, Klee EW, Ekker SC.

Hum Mutat. 2016 Oct;37(10):1097-105. doi: 10.1002/humu.23047. Epub 2016 Aug 8.

15.

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein.

Wang Y, Ding X, Wang S, Moser CD, Shaleh HM, Mohamed EA, Chaiteerakij R, Allotey LK, Chen G, Miyabe K, McNulty MS, Ndzengue A, Barr Fritcher EG, Knudson RA, Greipp PT, Clark KJ, Torbenson MS, Kipp BR, Zhou J, Barrett MT, Gustafson MP, Alberts SR, Borad MJ, Roberts LR.

Cancer Lett. 2016 Sep 28;380(1):163-73. doi: 10.1016/j.canlet.2016.05.017. Epub 2016 May 20.

16.

GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly.

Welker JM, Wierson WA, Wang Y, Poshusta TL, McNulty MS, Tisdale EE, Solin SL, Ekker SC, Clark KJ, McGrail M, Essner JJ.

Hum Gene Ther. 2016 Jun;27(6):423-4. doi: 10.1089/hum.2016.012. Epub 2016 May 6. No abstract available.

17.

Genome Engineering with TALE and CRISPR Systems in Neuroscience.

Lee HB, Sundberg BN, Sigafoos AN, Clark KJ.

Front Genet. 2016 Apr 6;7:47. doi: 10.3389/fgene.2016.00047. eCollection 2016. Review.

18.

Mayo Clinic Zebrafish Facility Overview.

Leveque RE, Clark KJ, Ekker SC.

Zebrafish. 2016 Jul;13 Suppl 1:S44-6. doi: 10.1089/zeb.2015.1227. Epub 2016 Mar 29.

19.

A highly infective plant-associated bacterium influences reproductive rates in pea aphids.

Hendry TA, Clark KJ, Baltrus DA.

R Soc Open Sci. 2016 Feb 10;3(2):150478. doi: 10.1098/rsos.150478. eCollection 2016 Feb.

20.

Allele-Specific Quantitative PCR for Accurate, Rapid, and Cost-Effective Genotyping.

Lee HB, Schwab TL, Koleilat A, Ata H, Daby CL, Cervera RL, McNulty MS, Bostwick HS, Clark KJ.

Hum Gene Ther. 2016 Jun;27(6):425-35. doi: 10.1089/hum.2016.011. Epub 2016 Mar 17.

21.

FusX: A Rapid One-Step Transcription Activator-Like Effector Assembly System for Genome Science.

Ma AC, McNulty MS, Poshusta TL, Campbell JM, Martínez-Gálvez G, Argue DP, Lee HB, Urban MD, Bullard CE, Blackburn PR, Man TK, Clark KJ, Ekker SC.

Hum Gene Ther. 2016 Jun;27(6):451-63. doi: 10.1089/hum.2015.172. Epub 2016 Mar 15.

22.

Elucidating cannabinoid biology in zebrafish (Danio rerio).

Krug RG 2nd, Clark KJ.

Gene. 2015 Oct 10;570(2):168-79. doi: 10.1016/j.gene.2015.07.036. Epub 2015 Jul 17. Review.

23.

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis.

Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC.

PLoS One. 2015 Jun 25;10(6):e0130688. doi: 10.1371/journal.pone.0130688. eCollection 2015.

24.

Identification and characterization of intestinal lactobacilli strains capable of degrading immunotoxic peptides present in gluten.

Duar RM, Clark KJ, Patil PB, Hernández C, Brüning S, Burkey TE, Madayiputhiya N, Taylor SL, Walter J.

J Appl Microbiol. 2015 Feb;118(2):515-27. doi: 10.1111/jam.12687. Epub 2014 Dec 18.

25.

Multiple factors influence the contribution of individual immunoglobulin light chain genes to the naïve antibody repertoire.

Fitzsimmons SP, Aydanian AG, Clark KJ, Shapiro MA.

BMC Immunol. 2014 Oct 30;15:51. doi: 10.1186/s12865-014-0051-2.

26.

Making designer mutants in model organisms.

Peng Y, Clark KJ, Campbell JM, Panetta MR, Guo Y, Ekker SC.

Development. 2014 Nov;141(21):4042-54. doi: 10.1242/dev.102186. Review.

27.

Performance of dairy cows fed silage and grain produced from second-generation insect-protected (Bacillus thuringiensis) corn (MON 89034), compared with parental line corn or reference corn.

Castillo-Lopez E, Clark KJ, Paz HA, Ramirez Ramirez HA, Klusmeyer TH, Hartnell GF, Kononoff PJ.

J Dairy Sci. 2014;97(6):3832-7. doi: 10.3168/jds.2014-7894. Epub 2014 Apr 14.

PMID:
24731628
28.

A transgenic zebrafish model for monitoring glucocorticoid receptor activity.

Krug RG 2nd, Poshusta TL, Skuster KJ, Berg MR, Gardner SL, Clark KJ.

Genes Brain Behav. 2014 Jun;13(5):478-87. doi: 10.1111/gbb.12135. Epub 2014 Apr 22.

29.

High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design.

Ma AC, Lee HB, Clark KJ, Ekker SC.

PLoS One. 2013 May 29;8(5):e65259. doi: 10.1371/journal.pone.0065259. Print 2013.

30.

A sequence-based variation map of zebrafish.

Patowary A, Purkanti R, Singh M, Chauhan R, Singh AR, Swarnkar M, Singh N, Pandey V, Torroja C, Clark MD, Kocher JP, Clark KJ, Stemple DL, Klee EW, Ekker SC, Scaria V, Sivasubbu S.

Zebrafish. 2013 Mar;10(1):15-20. doi: 10.1089/zeb.2012.0848.

31.

The CRISPR system--keeping zebrafish gene targeting fresh.

Blackburn PR, Campbell JM, Clark KJ, Ekker SC.

Zebrafish. 2013 Mar;10(1):116-8. doi: 10.1089/zeb.2013.9999. Epub 2013 Mar 28. Review.

32.

Mojo Hand, a TALEN design tool for genome editing applications.

Neff KL, Argue DP, Ma AC, Lee HB, Clark KJ, Ekker SC.

BMC Bioinformatics. 2013 Jan 16;14:1. doi: 10.1186/1471-2105-14-1.

33.

Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening.

Ding Y, Liu W, Deng Y, Jomok B, Yang J, Huang W, Clark KJ, Zhong TP, Lin X, Ekker SC, Xu X.

Circ Res. 2013 Feb 15;112(4):606-17. doi: 10.1161/CIRCRESAHA.112.300603. Epub 2013 Jan 2.

34.

The pharmacist "toolbox" for smoking cessation: a review of methods, medicines, and novel means to help patients along the path of smoking reduction to smoking cessation.

Wynn WP 3rd, Stroman RT, Almgren MM, Clark KJ.

J Pharm Pract. 2012 Dec;25(6):591-9. doi: 10.1177/0897190012460823. Review.

PMID:
23222855
35.

An in vivo method to quantify lymphangiogenesis in zebrafish.

Hoffman SJ, Psaltis PJ, Clark KJ, Spoon DB, Chue CD, Ekker SC, Simari RD.

PLoS One. 2012;7(9):e45240. doi: 10.1371/journal.pone.0045240. Epub 2012 Sep 13.

36.

In vivo genome editing using a high-efficiency TALEN system.

Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug RG 2nd, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, Ekker SC.

Nature. 2012 Nov 1;491(7422):114-8. doi: 10.1038/nature11537. Epub 2012 Sep 23.

37.

Major earthquakes occur regularly on an isolated plate boundary fault.

Berryman KR, Cochran UA, Clark KJ, Biasi GP, Langridge RM, Villamor P.

Science. 2012 Jun 29;336(6089):1690-3. doi: 10.1126/science.1218959.

38.

Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability.

Hoeppner LH, Phoenix KN, Clark KJ, Bhattacharya R, Gong X, Sciuto TE, Vohra P, Suresh S, Bhattacharya S, Dvorak AM, Ekker SC, Dvorak HF, Claffey KP, Mukhopadhyay D.

Blood. 2012 Sep 13;120(11):2167-73. doi: 10.1182/blood-2012-03-417824. Epub 2012 Jun 6.

39.

Functional analysis of slow myosin heavy chain 1 and myomesin-3 in sarcomere organization in zebrafish embryonic slow muscles.

Xu J, Gao J, Li J, Xue L, Clark KJ, Ekker SC, Du SJ.

J Genet Genomics. 2012 Feb;39(2):69-80. doi: 10.1016/j.jgg.2012.01.005. Epub 2012 Jan 21.

40.

Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins.

Liao HK, Wang Y, Noack Watt KE, Wen Q, Breitbach J, Kemmet CK, Clark KJ, Ekker SC, Essner JJ, McGrail M.

Dev Dyn. 2012 Feb;241(2):415-25. doi: 10.1002/dvdy.23725.

41.

The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development.

Bedell VM, Person AD, Larson JD, McLoon A, Balciunas D, Clark KJ, Neff KI, Nelson KE, Bill BR, Schimmenti LA, Beiraghi S, Ekker SC.

Development. 2012 Feb;139(4):793-804. doi: 10.1242/dev.071720.

42.

Zebrafish: a model for the study of addiction genetics.

Klee EW, Schneider H, Clark KJ, Cousin MA, Ebbert JO, Hooten WM, Karpyak VM, Warner DO, Ekker SC.

Hum Genet. 2012 Jun;131(6):977-1008. doi: 10.1007/s00439-011-1128-0. Epub 2011 Dec 30. Review.

43.

zfishbook: connecting you to a world of zebrafish revertible mutants.

Clark KJ, Argue DP, Petzold AM, Ekker SC.

Nucleic Acids Res. 2012 Jan;40(Database issue):D907-11. doi: 10.1093/nar/gkr957. Epub 2011 Nov 8.

44.

A TALE of two nucleases: gene targeting for the masses?

Clark KJ, Voytas DF, Ekker SC.

Zebrafish. 2011 Sep;8(3):147-9. doi: 10.1089/zeb.2011.9993.

45.

Transgenic zebrafish using transposable elements.

Clark KJ, Urban MD, Skuster KJ, Ekker SC.

Methods Cell Biol. 2011;104:137-49. doi: 10.1016/B978-0-12-374814-0.00008-2.

46.

Sleeping Beauty-mediated correction of Fanconi anemia type C.

Hyland KA, Olson ER, Clark KJ, Aronovich EL, Hackett PB, Blazar BR, Tolar J, Scott McIvor R.

J Gene Med. 2011 Sep;13(9):462-9. doi: 10.1002/jgm.1589.

PMID:
21766398
47.

Stressing zebrafish for behavioral genetics.

Clark KJ, Boczek NJ, Ekker SC.

Rev Neurosci. 2011;22(1):49-62. doi: 10.1515/RNS.2011.007. Review.

48.

In vivo protein trapping produces a functional expression codex of the vertebrate proteome.

Clark KJ, Balciunas D, Pogoda HM, Ding Y, Westcot SE, Bedell VM, Greenwood TM, Urban MD, Skuster KJ, Petzold AM, Ni J, Nielsen AL, Patowary A, Scaria V, Sivasubbu S, Xu X, Hammerschmidt M, Ekker SC.

Nat Methods. 2011 Jun;8(6):506-15. doi: 10.1038/nmeth.1606. Epub 2011 May 8.

49.

Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system.

Carlson DF, Garbe JR, Tan W, Martin MJ, Dobrinsky JR, Hackett PB, Clark KJ, Fahrenkrug SC.

Transgenic Res. 2011 Oct;20(5):1125-37. doi: 10.1007/s11248-010-9481-7. Epub 2011 Jan 9.

PMID:
21221779
50.

Development and application of bovine and porcine oligonucleotide arrays with protein-based annotation.

Garbe JR, Elsik CG, Antoniou E, Reecy JM, Clark KJ, Venkatraman A, Kim JW, Schnabel RD, Michael Dickens C, Wolfinger RD, Fahrenkrug SC, Taylor JF.

J Biomed Biotechnol. 2010;2010:453638. doi: 10.1155/2010/453638. Epub 2010 Dec 14.

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