Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 89

1.

Changes in prevalence of faecal occult blood positivity over time.

Goulding A, Clark GR, Anderson AS, Strachan JA, Fraser CG, Steele RJ.

J Med Screen. 2019 Jul 31:969141319866880. doi: 10.1177/0969141319866880. [Epub ahead of print] No abstract available.

PMID:
31364470
2.

SDHC epi-mutation testing in gastrointestinal stromal tumours and related tumours in clinical practice.

Casey RT, Ten Hoopen R, Ochoa E, Challis BG, Whitworth J, Smith PS, Martin JE, Clark GR, Rodger F, Maranian M, Allinson K, Madhu B, Roberts T, Campos L, Anstee J, Park SM, Marker A, Watts C, Bulusu VR, Giger OT, Maher ER.

Sci Rep. 2019 Jul 15;9(1):10244. doi: 10.1038/s41598-019-46124-9.

3.

MethylCal: Bayesian calibration of methylation levels.

Ochoa E, Zuber V, Fernandez-Jimenez N, Bilbao JR, Clark GR, Maher ER, Bottolo L.

Nucleic Acids Res. 2019 May 3. pii: gkz325. doi: 10.1093/nar/gkz325. [Epub ahead of print]

PMID:
31049595
4.

Translating in vivo metabolomic analysis of succinate dehydrogenase deficient tumours into clinical utility.

Casey RT, McLean MA, Madhu B, Challis BG, Ten Hoopen R, Roberts T, Clark GR, Pittfield D, Simpson HL, Bulusu VR, Allinson K, Happerfield L, Park SM, Marker A, Giger O, Maher ER, Gallagher FA.

JCO Precis Oncol. 2018 Mar 29;2:1-12. doi: 10.1200/PO.17.00191.

5.

Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes.

Gregson CL, Newell F, Leo PJ, Clark GR, Paternoster L, Marshall M, Forgetta V, Morris JA, Ge B, Bao X, Duncan Bassett JH, Williams GR, Youlten SE, Croucher PI, Davey Smith G, Evans DM, Kemp JP, Brown MA, Tobias JH, Duncan EL.

Bone. 2018 Sep;114:62-71. doi: 10.1016/j.bone.2018.06.001. Epub 2018 Jun 5.

6.

Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study.

Fewings E, Larionov A, Redman J, Goldgraben MA, Scarth J, Richardson S, Brewer C, Davidson R, Ellis I, Evans DG, Halliday D, Izatt L, Marks P, McConnell V, Verbist L, Mayes R, Clark GR, Hadfield J, Chin SF, Teixeira MR, Giger OT, Hardwick R, di Pietro M, O'Donovan M, Pharoah P, Caldas C, Fitzgerald RC, Tischkowitz M.

Lancet Gastroenterol Hepatol. 2018 Jul;3(7):489-498. doi: 10.1016/S2468-1253(18)30079-7. Epub 2018 Apr 27.

7.

Language continuity despite population replacement in Remote Oceania.

Posth C, Nägele K, Colleran H, Valentin F, Bedford S, Kami KW, Shing R, Buckley H, Kinaston R, Walworth M, Clark GR, Reepmeyer C, Flexner J, Maric T, Moser J, Gresky J, Kiko L, Robson KJ, Auckland K, Oppenheimer SJ, Hill AVS, Mentzer AJ, Zech J, Petchey F, Roberts P, Jeong C, Gray RD, Krause J, Powell A.

Nat Ecol Evol. 2018 Apr;2(4):731-740. doi: 10.1038/s41559-018-0498-2. Epub 2018 Feb 27.

8.

Clinical and Molecular Features of Renal and Pheochromocytoma/Paraganglioma Tumor Association Syndrome (RAPTAS): Case Series and Literature Review.

Casey RT, Warren AY, Martin JE, Challis BG, Rattenberry E, Whitworth J, Andrews KA, Roberts T, Clark GR, West H, Smith PS, Docquier FM, Rodger F, Murray V, Simpson HL, Wallis Y, Giger O, Tran M, Tomkins S, Stewart GD, Park SM, Woodward ER, Maher ER.

J Clin Endocrinol Metab. 2017 Nov 1;102(11):4013-4022. doi: 10.1210/jc.2017-00562. Review.

9.

SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity.

Casey RT, Ascher DB, Rattenberry E, Izatt L, Andrews KA, Simpson HL, Challis B, Park SM, Bulusu VR, Lalloo F, Pires DEV, West H, Clark GR, Smith PS, Whitworth J, Papathomas TG, Taniere P, Savisaar R, Hurst LD, Woodward ER, Maher ER.

Mol Genet Genomic Med. 2017 Mar 2;5(3):237-250. doi: 10.1002/mgg3.279. eCollection 2017 May.

10.

Broadening the phenotypic spectrum of POP1-skeletal dysplasias: identification of POP1 mutations in a mild and severe skeletal dysplasia.

Barraza-García J, Rivera-Pedroza CI, Hisado-Oliva A, Belinchón-Martínez A, Sentchordi-Montané L, Duncan EL, Clark GR, Del Pozo A, Ibáñez-Garikano K, Offiah A, Prieto-Matos P, Cormier-Daire V, Heath KE.

Clin Genet. 2017 Jul;92(1):91-98. doi: 10.1111/cge.12964. Epub 2017 Feb 22.

11.

Genomic insights into the peopling of the Southwest Pacific.

Skoglund P, Posth C, Sirak K, Spriggs M, Valentin F, Bedford S, Clark GR, Reepmeyer C, Petchey F, Fernandes D, Fu Q, Harney E, Lipson M, Mallick S, Novak M, Rohland N, Stewardson K, Abdullah S, Cox MP, Friedlaender FR, Friedlaender JS, Kivisild T, Koki G, Kusuma P, Merriwether DA, Ricaut FX, Wee JT, Patterson N, Krause J, Pinhasi R, Reich D.

Nature. 2016 Oct 27;538(7626):510-513. doi: 10.1038/nature19844. Epub 2016 Oct 3.

12.

Nephroblastomatosis or Wilms tumor in a fourth patient with a somatic PIK3CA mutation.

Gripp KW, Baker L, Kandula V, Conard K, Scavina M, Napoli JA, Griffin GC, Thacker M, Knox RG, Clark GR, Parker VE, Semple R, Mirzaa G, Keppler-Noreuil KM.

Am J Med Genet A. 2016 Oct;170(10):2559-69. doi: 10.1002/ajmg.a.37758. Epub 2016 May 18. Review.

13.

Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.

Castillo SD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M, Vanhaesebroeck B.

Sci Transl Med. 2016 Mar 30;8(332):332ra43. doi: 10.1126/scitranslmed.aad9982.

14.

Strand breakage by decay of DNA-bound 124I provides a basis for combined PET imaging and Auger endoradiotherapy.

Lobachevsky P, Clark GR, Pytel PD, Leung B, Skene C, Andrau L, White JM, Karagiannis T, Cullinane C, Lee BQ, Stuchbery A, Kibedi T, Hicks RJ, Martin RF.

Int J Radiat Biol. 2016 Nov;92(11):686-697. Epub 2016 Feb 23.

PMID:
26902391
15.

Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass Cases.

Gregson CL, Wheeler L, Hardcastle SA, Appleton LH, Addison KA, Brugmans M, Clark GR, Ward KA, Paggiosi M, Stone M, Thomas J, Agarwal R, Poole KE, McCloskey E, Fraser WD, Williams E, Bullock AN, Davey Smith G, Brown MA, Tobias JH, Duncan EL.

J Bone Miner Res. 2016 Mar;31(3):640-9. doi: 10.1002/jbmr.2706. Epub 2015 Oct 6.

16.

The genetics of osteoporosis.

Clark GR, Duncan EL.

Br Med Bull. 2015 Mar;113(1):73-81. doi: 10.1093/bmb/ldu042. Epub 2015 Jan 29. Review.

PMID:
25634850
17.

Ruthenium and osmium complexes of hemilabile chiral monophosphinite ligands derived from 1D-pinitol or 1D-chiro-inositol as catalysts for asymmetric hydrogenation reactions.

Slade AT, Lensink C, Falshaw A, Clark GR, Wright LJ.

Dalton Trans. 2014 Dec 7;43(45):17163-71. doi: 10.1039/c4dt02558j.

PMID:
25315464
18.

Germline FH mutations presenting with pheochromocytoma.

Clark GR, Sciacovelli M, Gaude E, Walsh DM, Kirby G, Simpson MA, Trembath RC, Berg JN, Woodward ER, Kinning E, Morrison PJ, Frezza C, Maher ER.

J Clin Endocrinol Metab. 2014 Oct;99(10):E2046-50. doi: 10.1210/jc.2014-1659. Epub 2014 Jul 8.

PMID:
25004247
19.

Stone tools from the ancient Tongan state reveal prehistoric interaction centers in the Central Pacific.

Clark GR, Reepmeyer C, Melekiola N, Woodhead J, Dickinson WR, Martinsson-Wallin H.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10491-6. doi: 10.1073/pnas.1406165111. Epub 2014 Jul 7.

20.

COL1A1 C-propeptide cleavage site mutation causes high bone mass, bone fragility and jaw lesions: a new cause of gnathodiaphyseal dysplasia?

McInerney-Leo AM, Duncan EL, Leo PJ, Gardiner B, Bradbury LA, Harris JE, Clark GR, Brown MA, Zankl A.

Clin Genet. 2015 Jul;88(1):49-55. doi: 10.1111/cge.12440. Epub 2014 Aug 15.

PMID:
24891183
21.

Controlled translocation of palladium(II) within a 22 ring atom macrocyclic ligand.

Burgess MG, Zafar MN, Horner ST, Clark GR, Wright LJ.

Dalton Trans. 2014 Dec 7;43(45):17006-16. doi: 10.1039/c4dt00765d.

PMID:
24869561
22.

Cross-bridged cyclen or cyclam Co(III) complexes containing cytotoxic ligands as hypoxia-activated prodrugs.

Chang JY, Lu GL, Stevenson RJ, Brothers PJ, Clark GR, Botting KJ, Ferry DM, Tercel M, Wilson WR, Denny WA, Ware DC.

Inorg Chem. 2013 Jul 1;52(13):7688-98. doi: 10.1021/ic4006967. Epub 2013 Jun 17.

PMID:
23773210
23.

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-Gómez C, Palsson ST, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtimäki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F.

Nat Genet. 2012 Apr 15;44(5):491-501. doi: 10.1038/ng.2249.

24.

Multicentric carpotarsal osteolysis is caused by mutations clustering in the amino-terminal transcriptional activation domain of MAFB.

Zankl A, Duncan EL, Leo PJ, Clark GR, Glazov EA, Addor MC, Herlin T, Kim CA, Leheup BP, McGill J, McTaggart S, Mittas S, Mitchell AL, Mortier GR, Robertson SP, Schroeder M, Terhal P, Brown MA.

Am J Hum Genet. 2012 Mar 9;90(3):494-501. doi: 10.1016/j.ajhg.2012.01.003. Epub 2012 Mar 1. Erratum in: Am J Hum Genet. 2014 Apr 3;94(4):643.

25.

The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages.

Clark GR, Pytel PD, Squire CJ.

Nucleic Acids Res. 2012 Jul;40(12):5731-8. doi: 10.1093/nar/gks193. Epub 2012 Feb 28.

26.

Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia.

Glazov EA, Zankl A, Donskoi M, Kenna TJ, Thomas GP, Clark GR, Duncan EL, Brown MA.

PLoS Genet. 2011 Mar;7(3):e1002027. doi: 10.1371/journal.pgen.1002027. Epub 2011 Mar 24.

27.

Molecular diagnosis for heterogeneous genetic diseases with targeted high-throughput DNA sequencing applied to retinitis pigmentosa.

Simpson DA, Clark GR, Alexander S, Silvestri G, Willoughby CE.

J Med Genet. 2011 Mar;48(3):145-51. doi: 10.1136/jmg.2010.083568. Epub 2010 Dec 8.

PMID:
21147909
28.

Syntheses of 8-quinolinolatocobalt(III) complexes containing cyclen based auxiliary ligands as models for hypoxia-activated prodrugs.

Chang JY, Stevenson RJ, Lu GL, Brothers PJ, Clark GR, Denny WA, Ware DC.

Dalton Trans. 2010 Dec 28;39(48):11535-50. doi: 10.1039/c0dt01142h. Epub 2010 Nov 22.

PMID:
21103540
29.

Functionalization of metallabenzenes through nucleophilic aromatic substitution of hydrogen.

Clark GR, Ferguson LA, McIntosh AE, Söhnel T, Wright LJ.

J Am Chem Soc. 2010 Sep 29;132(38):13443-52. doi: 10.1021/ja105239t.

PMID:
20822136
30.

Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa.

Clark GR, Crowe P, Muszynska D, O'Prey D, O'Neill J, Alexander S, Willoughby CE, McKay GJ, Silvestri G, Simpson DA.

Ophthalmology. 2010 Nov;117(11):2169-77.e3. doi: 10.1016/j.ophtha.2010.02.029. Epub 2010 Jun 29.

PMID:
20591486
31.

Reductive coupling and protonation leading to diboron corroles with a B-H-B bridge.

Albrett AM, Boyd PD, Clark GR, Gonzalez E, Ghosh A, Brothers PJ.

Dalton Trans. 2010 May 7;39(17):4032-4. doi: 10.1039/c002885c. Epub 2010 Mar 16.

PMID:
20390165
32.

A concise approach to the core structures of pinnaic acid and halichlorine.

Yang SH, Clark GR, Caprio V.

Org Biomol Chem. 2009 Jul 21;7(14):2981-90. doi: 10.1039/b903904j. Epub 2009 Jun 15.

PMID:
19582309
33.

Bis[(1S*,2S*)-trans-1,2-bis-(diphenyl-phosphin-oxy)cyclo-hexa-ne]chlorido-ruthenium(II) trifluoro-methane-sulfonate dichloro-methane disolvate.

Clark GR, Lensink C, Slade AT, Wright LJ.

Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 20;65(Pt 7):m804-5. doi: 10.1107/S1600536809023034.

34.

Corrole as a binucleating ligand: preparation, molecular structure and density functional theory study of diboron corroles.

Albrett AM, Conradie J, Boyd PD, Clark GR, Ghosh A, Brothers PJ.

J Am Chem Soc. 2008 Mar 12;130(10):2888-9. doi: 10.1021/ja077785u. Epub 2008 Feb 16. No abstract available.

PMID:
18278914
35.

Synthetic routes to mixed-ligand cobalt(III) dithiocarbamato complexes containing imidazole, amine and pyridine donors and the X-ray crystal structure of a cobalt(III) bis(dithiocarbamato) histamine complex.

Hodgson MC, Brothers PJ, Clark GR, Ware DC.

J Inorg Biochem. 2008 Apr;102(4):789-97. doi: 10.1016/j.jinorgbio.2007.11.016. Epub 2007 Dec 7.

PMID:
18262652
36.

Dimethyl 7a-carbonyl-2-meth-oxy-7a,7a-bis-(triphenyl-phosphino)-7a-ruthena-1-benzofuran-4,7-dicarboxyl-ate.

Clark GR, Roper WR, Tonei DM, Wright LJ.

Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 13;65(Pt 1):m52. doi: 10.1107/S1600536808040944.

37.

3,5-Dinitro-benzyl methane-sulfonate.

Khan GS, Clark GR, Barker D.

Acta Crystallogr Sect E Struct Rep Online. 2008 Jul 12;64(Pt 8):o1470. doi: 10.1107/S1600536808020850.

38.

2,2'-(3,5-Dinitro-benzyl-imino)diethanol.

Khan GS, Clark GR, Barker D.

Acta Crystallogr Sect E Struct Rep Online. 2008 Jun 13;64(Pt 7):o1253. doi: 10.1107/S1600536808017066.

39.

N-{3-[Bis(2-hydroxy-ethyl)amino-meth-yl]-5-nitro-phen-yl}benzamide.

Mai A, Khan GS, Clark GR, Barker D.

Acta Crystallogr Sect E Struct Rep Online. 2008 May 3;64(Pt 6):o978-9. doi: 10.1107/S1600536808009410.

40.

N-[3-(tert-Butyl-dimethyl-siloxymeth-yl)-5-nitro-phen-yl]acetamide.

Khan GS, Clark GR, Barker D.

Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 27;64(Pt 10):o2031. doi: 10.1107/S1600536808030717.

41.

Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease.

Goris A, Williams-Gray CH, Clark GR, Foltynie T, Lewis SJ, Brown J, Ban M, Spillantini MG, Compston A, Burn DJ, Chinnery PF, Barker RA, Sawcer SJ.

Ann Neurol. 2007 Aug;62(2):145-53.

PMID:
17683088
42.

Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis.

Pearce AN, Chia EW, Berridge MV, Clark GR, Harper JL, Larsen L, Maas EW, Page MJ, Perry NB, Webb VL, Copp BR.

J Nat Prod. 2007 Jun;70(6):936-40. Epub 2007 May 11.

PMID:
17497807
43.

7,7-Dimethyl-5H-dibenzo[e,i][1,4,8]triazacycloundecine-6,9,15(7H,8H,14H)-trione pyridine solvate.

Morris JC, Gordon-Wylie SW, Clark GR.

Acta Crystallogr C. 2006 Dec;62(Pt 12):o674-6. Epub 2006 Nov 10.

PMID:
17148909
44.

Coordination chemistry of 1,4-bis-carboxymethylcyclam, H(2)(1,4-bcc).

Tonei DM, Ware DC, Brothers PJ, Plieger PG, Clark GR.

Dalton Trans. 2006 Jan 7;(1):152-8. Epub 2005 Nov 14.

PMID:
16357971
45.

C-suite talent development. The importance of board support for achieving excellence.

Rice JA, Clark GR.

Healthc Exec. 2005 Nov-Dec;20(6):46, 48. No abstract available.

PMID:
16320488
46.

What should boards be doing? Or, its my backyard.

Clark GR; Governance Institute.

Healthc Exec. 2004 Jul-Aug;19(4):46-7. No abstract available.

PMID:
15281593
47.

Anionic carbonato and oxalato cobalt(III) nitrogen mustard complexes.

Craig PR, Brothers PJ, Clark GR, Wilson WR, Denny WA, Ware DC.

Dalton Trans. 2004 Feb 21;(4):611-8. Epub 2004 Jan 20.

PMID:
15252524
48.

In vitro studies with methylproamine: a potent new radioprotector.

Martin RF, Broadhurst S, Reum ME, Squire CJ, Clark GR, Lobachevsky PN, White JM, Clark C, Sy D, Spotheim-Maurizot M, Kelly DP.

Cancer Res. 2004 Feb 1;64(3):1067-70.

49.

Structure of the first parallel DNA quadruplex-drug complex.

Clark GR, Pytel PD, Squire CJ, Neidle S.

J Am Chem Soc. 2003 Apr 9;125(14):4066-7.

PMID:
12670225
50.

Intermolecular interactions and water structure in a condensed phase B-DNA crystal.

Clark GR, Squire CJ, Baker LJ, Martin RF, White J.

Nucleic Acids Res. 2000 Mar 1;28(5):1259-65.

Supplemental Content

Loading ...
Support Center