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Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.

Roe K, Giordano D, Young LB, Draves KE, Holder U, Suthar MS, Gale M Jr, Clark EA.

PLoS One. 2019 Jun 26;14(6):e0218928. doi: 10.1371/journal.pone.0218928. eCollection 2019.


GR and LSD1/KDM1A-Targeted Gene Activation Requires Selective H3K4me2 Demethylation at Enhancers.

Clark EA, Wu F, Chen Y, Kang P, Kaiser UB, Fang R, Shi YG.

Cell Rep. 2019 Jun 18;27(12):3522-3532.e3. doi: 10.1016/j.celrep.2019.05.062.


Pregnancy-Associated Death in Utah: Contribution of Drug-Induced Deaths.

Smid MC, Stone NM, Baksh L, Debbink MP, Einerson BD, Varner MW, Gordon AJ, Clark EAS.

Obstet Gynecol. 2019 Jun;133(6):1131-1140. doi: 10.1097/AOG.0000000000003279.


Incidence and Risk Factors for Hospital Readmission or Unexpected Visits in Women Undergoing Unscheduled Cesarean Delivery.

La Rosa M, Jauk V, Saade GR, Boggess K, Longo S, Clark EAS, Esplin S, Cleary K, Wapner R, Letson K, Owens MY, Blackwell S, Szychowski JM, Andrews W, Tita AT; Cesarean Section Optimal Antibiotic Prophylaxis Trial Consortium.

Am J Perinatol. 2019 Mar 15. doi: 10.1055/s-0039-1683391. [Epub ahead of print]


Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery: A Secondary Analysis of a Randomized Clinical Trial.

Gyamfi-Bannerman C, Zupancic JAF, Sandoval G, Grobman WA, Blackwell SC, Tita ATN, Reddy UM, Jain L, Saade GR, Rouse DJ, Iams JD, Clark EAS, Thorp JM Jr, Chien EK, Peaceman AM, Gibbs RS, Swamy GK, Norton ME, Casey BM, Caritis SN, Tolosa JE, Sorokin Y, VanDorsten JP; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

JAMA Pediatr. 2019 Mar 11. doi: 10.1001/jamapediatrics.2019.0032. [Epub ahead of print] Erratum in: JAMA Pediatr. 2019 May 1;173(5):502.


Neonatal Outcomes Associated with Umbilical Cord Milking in Preterm Multiple Gestations.

Rodriguez CE, Metz TD, Patel S, Abbaszadeh M, Yoder BA, Bardsley T, Clark EAS.

Am J Perinatol. 2019 Mar 1. doi: 10.1055/s-0039-1679915. [Epub ahead of print]


Impact of Azithromycin-Based Extended-Spectrum Antibiotic Prophylaxis on Noninfectious Cesarean Wound Complications.

Ausbeck EB, Jauk VC, Boggess KA, Saade GR, Longo S, Clark EAS, Esplin S, Cleary K, Wapner R, Letson K, Owens M, Abramovici A, Ambalavanan N, Szychowski JM, Andrews W, Tita ATN; Cesarean Section Optimal Antibiotic Prophylaxis Trial Consortium.

Am J Perinatol. 2019 Jul;36(9):886-890. doi: 10.1055/s-0039-1679914. Epub 2019 Feb 19.


Association of Gestational Diabetes Mellitus With Neonatal Respiratory Morbidity.

Werner EF, Romano ME, Rouse DJ, Sandoval G, Gyamfi-Bannerman C, Blackwell SC, Tita ATN, Reddy UM, Jain L, Saade GR, Iams JD, Clark EAS, Thorp JM Jr, Chien EK, Peaceman AM, Swamy GK, Norton ME, Casey BM, Caritis SN, Tolosa JE, Sorokin Y; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU)*.

Obstet Gynecol. 2019 Feb;133(2):349-353. doi: 10.1097/AOG.0000000000003053.


Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.

Tron AE, Belmonte MA, Adam A, Aquila BM, Boise LH, Chiarparin E, Cidado J, Embrey KJ, Gangl E, Gibbons FD, Gregory GP, Hargreaves D, Hendricks JA, Johannes JW, Johnstone RW, Kazmirski SL, Kettle JG, Lamb ML, Matulis SM, Nooka AK, Packer MJ, Peng B, Rawlins PB, Robbins DW, Schuller AG, Su N, Yang W, Ye Q, Zheng X, Secrist JP, Clark EA, Wilson DM, Fawell SE, Hird AW.

Nat Commun. 2018 Dec 17;9(1):5341. doi: 10.1038/s41467-018-07551-w.


CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity.

Clark EA, Giltiay NV.

Front Immunol. 2018 Sep 28;9:2235. doi: 10.3389/fimmu.2018.02235. eCollection 2018. Review.


Increasing IUD and Implant Use Among Those at Risk of a Subsequent Preterm Birth: A Randomized Controlled Trial of Postpartum Contraceptive Counseling.

Torres LN, Turok DK, Clark EAS, Sanders JN, Godfrey EM.

Womens Health Issues. 2018 Sep - Oct;28(5):393-400. doi: 10.1016/j.whi.2018.05.003. Epub 2018 Jul 4.


Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study.

Bauer ME, Housey M, Bauer ST, Behrmann S, Chau A, Clancy C, Clark EAS, Einav S, Langen E, Leffert L, Lin S, Madapu M, Maile MD, McQuaid-Hanson E, Priessnitz K, Sela HY, Shah A, Sobolewski P, Toledo P, Tsen LC, Bateman BT.

Anesth Analg. 2018 Aug 29. doi: 10.1213/ANE.0000000000003709. [Epub ahead of print]


Egg consumption may improve factors associated with glycemic control and insulin sensitivity in adults with pre- and type II diabetes.

Pourafshar S, Akhavan NS, George KS, Foley EM, Johnson SA, Keshavarz B, Navaei N, Davoudi A, Clark EA, Arjmandi BH.

Food Funct. 2018 Aug 15;9(8):4469-4479. doi: 10.1039/c8fo00194d.


Institutional Protocols for Vaginal Preparation With Antiseptic Solution and Surgical Site Infection Rate in Women Undergoing Cesarean Delivery During Labor.

La Rosa M, Jauk V, Saade G, Boggess K, Longo S, Clark EAS, Esplin S, Cleary K, Wapner R, Letson K, Owens MY, Blackwell S, Szychowski JM, Andrews WW, Tita AT; Cesarean Section Optimal Antibiotic Prophylaxis Trial Consortium.

Obstet Gynecol. 2018 Aug;132(2):371-376. doi: 10.1097/AOG.0000000000002745.


Clinical Variables Associated With Adverse Maternal Outcomes in Puerperal Group A Streptococci Infection.

Kaiser JE, Bakian AV, Silver RM, Clark EAS.

Obstet Gynecol. 2018 Jul;132(1):179-184. doi: 10.1097/AOG.0000000000002648.


Regulation of B-lineage cells by caspase 6.

Watanabe C, Shu GL, Giltiay NV, Clark EA.

Immunol Cell Biol. 2018 Nov;96(10):1072-1082. doi: 10.1111/imcb.12172. Epub 2018 Jun 22.


Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth.

Clark EAS, Weiner SJ, Rouse DJ, Mercer BM, Reddy UM, Iams JD, Wapner RJ, Sorokin Y, Malone FD, O'Sullivan MJ, Peaceman AM, Hankins GDV, Dudley DJ, Caritis SN; Eunice Kennedy Shriver National Institute of Child Health Human Development Maternal-Fetal Medicine Units (MFMU) Network.

Am J Perinatol. 2018 Aug;35(10):1012-1022. doi: 10.1055/s-0038-1635109. Epub 2018 Mar 6.


Splenic macrophages are required for protective innate immunity against West Nile virus.

Bryan MA, Giordano D, Draves KE, Green R, Gale M Jr, Clark EA.

PLoS One. 2018 Feb 6;13(2):e0191690. doi: 10.1371/journal.pone.0191690. eCollection 2018.


Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization.

Giordano D, Draves KE, Young LB, Roe K, Bryan MA, Dresch C, Richner JM, Diamond MS, Gale M Jr, Clark EA.

PLoS Pathog. 2017 Nov 27;13(11):e1006743. doi: 10.1371/journal.ppat.1006743. eCollection 2017 Nov.


Transfusion Preparedness Strategies for Obstetric Hemorrhage: A Cost-Effectiveness Analysis.

Einerson BD, Stehlikova Z, Nelson RE, Bellows BK, Kawamoto K, Clark EAS.

Obstet Gynecol. 2017 Dec;130(6):1347-1355. doi: 10.1097/AOG.0000000000002359.


The interplay of CD150 and CD180 receptor pathways contribute to the pathobiology of chronic lymphocytic leukemia B cells by selective inhibition of Akt and MAPK signaling.

Gordiienko I, Shlapatska L, Kholodniuk V, Sklyarenko L, Gluzman DF, Clark EA, Sidorenko SP.

PLoS One. 2017 Oct 5;12(10):e0185940. doi: 10.1371/journal.pone.0185940. eCollection 2017.


Military Sexual Trauma in Female Veterans is Associated With Chronic Pain Conditions.

Cichowski SB, Rogers RG, Clark EA, Murata E, Murata A, Murata G.

Mil Med. 2017 Sep;182(9):e1895-e1899. doi: 10.7205/MILMED-D-16-00393.


3D printing of tablets using inkjet with UV photoinitiation.

Clark EA, Alexander MR, Irvine DJ, Roberts CJ, Wallace MJ, Sharpe S, Yoo J, Hague RJM, Tuck CJ, Wildman RD.

Int J Pharm. 2017 Aug 30;529(1-2):523-530. doi: 10.1016/j.ijpharm.2017.06.085. Epub 2017 Jun 30.


Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer.

Choueiri TK, Plimack E, Arkenau HT, Jonasch E, Heng DYC, Powles T, Frigault MM, Clark EA, Handzel AA, Gardner H, Morgan S, Albiges L, Pal SK.

J Clin Oncol. 2017 Sep 10;35(26):2993-3001. doi: 10.1200/JCO.2017.72.2967. Epub 2017 Jun 23.


Perinatal outcomes associated with intrahepatic cholestasis of pregnancy.

Herrera CA, Manuck TA, Stoddard GJ, Varner MW, Esplin S, Clark EAS, Silver RM, Eller AG.

J Matern Fetal Neonatal Med. 2018 Jul;31(14):1913-1920. doi: 10.1080/14767058.2017.1332036. Epub 2017 Jun 5.


CD22 is required for formation of memory B cell precursors within germinal centers.

Chappell CP, Draves KE, Clark EA.

PLoS One. 2017 Mar 27;12(3):e0174661. doi: 10.1371/journal.pone.0174661. eCollection 2017.


Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis.

Boggess KA, Tita A, Jauk V, Saade G, Longo S, Clark EA, Esplin S, Cleary K, Wapner R, Letson K, Owens M, Blackwell S, Beamon C, Szychowski JM, Andrews W; Cesarean Section Optimal Antibiotic Prophylaxis Trial Consortium.

Obstet Gynecol. 2017 Mar;129(3):481-485. doi: 10.1097/AOG.0000000000001899.


Antenatal Magnesium Sulfate, Necrotizing Enterocolitis, and Death among Neonates < 28 Weeks Gestation.

Kamyar M, Clark EA, Yoder BA, Varner MW, Manuck TA.

AJP Rep. 2016 Mar;6(1):e148-54. doi: 10.1055/s-0036-1581059.


Antenatal Betamethasone for Women at Risk for Late Preterm Delivery.

Gyamfi-Bannerman C, Thom EA, Blackwell SC, Tita AT, Reddy UM, Saade GR, Rouse DJ, McKenna DS, Clark EA, Thorp JM Jr, Chien EK, Peaceman AM, Gibbs RS, Swamy GK, Norton ME, Casey BM, Caritis SN, Tolosa JE, Sorokin Y, VanDorsten JP, Jain L; NICHD Maternal–Fetal Medicine Units Network.

N Engl J Med. 2016 Apr 7;374(14):1311-20. doi: 10.1056/NEJMoa1516783. Epub 2016 Feb 4.


Neonatal Genetic Variation in Steroid Metabolism and Key Respiratory Function Genes and Perinatal Outcomes in Single and Multiple Courses of Corticosteroids.

Borowski KS, Clark EA, Lai Y, Wapner RJ, Sorokin Y, Peaceman AM, Iams JD, Leveno KJ, Harper M, Caritis SN, Miodovnik M, Mercer BM, Thorp JM Jr, O'Sullivan MJ, Ramin SM, Carpenter MW, Rouse DJ, Sibai B; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

Am J Perinatol. 2015 Oct;32(12):1126-32. doi: 10.1055/s-0035-1549217. Epub 2015 May 8.


Synapse and genome: An elusive tête-à-tête.

Clark EA, Nelson SB.

Sci Signal. 2015 Sep 29;8(396):pe2. doi: 10.1126/scisignal.aad2441. Review.


Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites.

Yu T, Campbell SC, Stockmann C, Tak C, Schoen K, Clark EA, Varner MW, Spigarelli MG, Sherwin CM.

J Clin Pharmacol. 2016 May;56(5):590-6. doi: 10.1002/jcph.632. Epub 2015 Dec 22.


The heritability of gestational age in a two-million member cohort: implications for spontaneous preterm birth.

Wu W, Witherspoon DJ, Fraser A, Clark EA, Rogers A, Stoddard GJ, Manuck TA, Chen K, Esplin MS, Smith KR, Varner MW, Jorde LB.

Hum Genet. 2015 Jul;134(7):803-8. doi: 10.1007/s00439-015-1558-1. Epub 2015 Apr 29.


Determination of Abraham model solute descriptors for the monomeric and dimeric forms of trans-cinnamic acid using measured solubilities from the Open Notebook Science Challenge.

Bradley JC, Abraham MH, Acree WE Jr, Lang AS, Beck SN, Bulger DA, Clark EA, Condron LN, Costa ST, Curtin EM, Kurtu SB, Mangir MI, McBride MJ.

Chem Cent J. 2015 Mar 22;9:11. doi: 10.1186/s13065-015-0080-9. eCollection 2015.


The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models.

Schuller AG, Barry ER, Jones RD, Henry RE, Frigault MM, Beran G, Linsenmayer D, Hattersley M, Smith A, Wilson J, Cairo S, Déas O, Nicolle D, Adam A, Zinda M, Reimer C, Fawell SE, Clark EA, D'Cruz CM.

Clin Cancer Res. 2015 Jun 15;21(12):2811-9. doi: 10.1158/1078-0432.CCR-14-2685. Epub 2015 Mar 16.


Rewiring of sIgM-Mediated Intracellular Signaling through the CD180 Toll-like Receptor.

Porakishvili N, Vispute K, Steele AJ, Rajakaruna N, Kulikova N, Tsertsvadze T, Nathwani A, Damle RN, Clark EA, Rai KR, Chiorazzi N, Lydyard PM.

Mol Med. 2015 Apr;21(1):46-57. doi: 10.2119/molmed.2014.00265. Epub 2015 Jan 14.


Neonatal magnesium levels correlate with motor outcomes in premature infants: a long-term retrospective cohort study.

Doll E, Wilkes J, Cook LJ, Korgenski EK, Faix RG, Yoder BA, Srivastava R, Sherwin CM, Spigarelli MG, Clark EA, Bonkowsky JL.

Front Pediatr. 2014 Nov 5;2:120. doi: 10.3389/fped.2014.00120. eCollection 2014.


A Short History of the B-Cell-Associated Surface Molecule CD40.

Clark EA.

Front Immunol. 2014 Sep 29;5:472. doi: 10.3389/fimmu.2014.00472. eCollection 2014. Review.


Intracellular TCR-signaling pathway: novel markers for lymphoma diagnosis and potential therapeutic targets.

Agostinelli C, Rizvi H, Paterson J, Shende V, Akarca AU, Agostini E, Fuligni F, Righi S, Spagnolo S, Piccaluga PP, Clark EA, Pileri SA, Marafioti T.

Am J Surg Pathol. 2014 Oct;38(10):1349-59. doi: 10.1097/PAS.0000000000000309.


Genetic variants associated with severe retinopathy of prematurity in extremely low birth weight infants.

Hartnett ME, Morrison MA, Smith S, Yanovitch TL, Young TL, Colaizy T, Momany A, Dagle J, Carlo WA, Clark EA, Page G, Murray J, DeAngelis MM, Cotten CM; Genomics Subcommittee.

Invest Ophthalmol Vis Sci. 2014 Aug 12;55(10):6194-203. doi: 10.1167/iovs.14-14841.


Nitric oxide regulates BAFF expression and T cell-independent antibody responses.

Giordano D, Draves KE, Li C, Hohl TM, Clark EA.

J Immunol. 2014 Aug 1;193(3):1110-20. doi: 10.4049/jimmunol.1303158. Epub 2014 Jun 20.


Effect of umbilical cord milking on morbidity and survival in extremely low gestational age neonates.

Patel S, Clark EA, Rodriguez CE, Metz TD, Abbaszadeh M, Yoder BA.

Am J Obstet Gynecol. 2014 Nov;211(5):519.e1-7. doi: 10.1016/j.ajog.2014.05.037. Epub 2014 May 29.


Concise review: MicroRNA function in multipotent mesenchymal stromal cells.

Clark EA, Kalomoiris S, Nolta JA, Fierro FA.

Stem Cells. 2014 May;32(5):1074-82. Review.


Targeting antigens through blood dendritic cell antigen 2 on plasmacytoid dendritic cells promotes immunologic tolerance.

Chappell CP, Giltiay NV, Draves KE, Chen C, Hayden-Ledbetter MS, Shlomchik MJ, Kaplan DH, Clark EA.

J Immunol. 2014 Jun 15;192(12):5789-5801. doi: 10.4049/jimmunol.1303259. Epub 2014 May 14.


Intrapartum magnesium sulfate and the potential for cardiopulmonary drug-drug interactions.

Campbell SC, Stockmann C, Balch A, Clark EA, Kamyar M, Varner M, Korgenski EK, Bonkowsky JL, Spigarelli MG, Sherwin CM.

Ther Drug Monit. 2014 Aug;36(4):544-8. doi: 10.1097/FTD.0000000000000050.


Controlling immune responses by targeting antigens to dendritic cell subsets and B cells.

Chappell CP, Giltiay NV, Dresch C, Clark EA.

Int Immunol. 2014 Jan;26(1):3-11. doi: 10.1093/intimm/dxt059. Epub 2013 Nov 27. Review.


Maternal prenatal weight gain and autism spectrum disorders.

Bilder DA, Bakian AV, Viskochil J, Clark EA, Botts EL, Smith KR, Pimentel R, McMahon WM, Coon H.

Pediatrics. 2013 Nov;132(5):e1276-83. doi: 10.1542/peds.2013-1188. Epub 2013 Oct 28.


Maternal magnesium sulphate exposure predicts neonatal magnesium blood concentrations.

Sherwin CM, Balch A, Campbell SC, Fredrickson J, Clark EA, Varner M, Stockmann C, Korgenski EK, Bonkowsky JL, Spigarelli MG.

Basic Clin Pharmacol Toxicol. 2014 Apr;114(4):318-22. doi: 10.1111/bcpt.12166. Epub 2013 Dec 11.


Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells.

Giltiay NV, Chappell CP, Sun X, Kolhatkar N, Teal TH, Wiedeman AE, Kim J, Tanaka L, Buechler MB, Hamerman JA, Imanishi-Kari T, Clark EA, Elkon KB.

J Exp Med. 2013 Nov 18;210(12):2773-89. doi: 10.1084/jem.20122798. Epub 2013 Oct 21.

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