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Items: 1 to 50 of 298

1.

Site-Selective Functionalization of (sp3)C-H Bonds Catayzed by Artificial Metalloenzymes Containing an Iridium-Porphyrin Cofactor.

Gu Y, Natoli SN, Liu Z, Clark DS, Hartwig JF.

Angew Chem Int Ed Engl. 2019 Jul 29. doi: 10.1002/anie.201907460. [Epub ahead of print]

PMID:
31356719
2.

Enhanced Enzyme Activity through Scaffolding on Customizable Self-Assembling Protein Filaments.

Lim S, Jung GA, Glover DJ, Clark DS.

Small. 2019 May;15(20):e1805558. doi: 10.1002/smll.201805558. Epub 2019 Mar 28.

PMID:
30920729
3.

Shaping the Future of Protein Engineering.

Glover DJ, Xu D, Clark DS.

Biochemistry. 2019 Feb 26;58(8):1019-1021. doi: 10.1021/acs.biochem.8b01322. Epub 2019 Feb 6. No abstract available.

PMID:
30726062
4.

Engineering bioorthogonal protein-polymer hybrid hydrogel as a functional protein immobilization platform.

Lim S, Jung GA, Muckom RJ, Glover DJ, Clark DS.

Chem Commun (Camb). 2019 Jan 15;55(6):806-809. doi: 10.1039/c8cc08720b.

PMID:
30574651
5.

Prefoldins in Archaea.

Lim S, Glover DJ, Clark DS.

Adv Exp Med Biol. 2018;1106:11-23. doi: 10.1007/978-3-030-00737-9_2. Review.

PMID:
30484150
6.

Assembly of Multicomponent Protein Filaments Using Engineered Subunit Interfaces.

Glover DJ, Lim S, Xu D, Sloan NB, Zhang Y, Clark DS.

ACS Synth Biol. 2018 Oct 19;7(10):2447-2456. doi: 10.1021/acssynbio.8b00241. Epub 2018 Oct 3.

PMID:
30234970
7.

High-throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell culture.

Nierode GJ, Gopal S, Kwon P, Clark DS, Schaffer DV, Dordick JS.

Biotechnol Bioeng. 2019 Jan;116(1):168-180. doi: 10.1002/bit.26839. Epub 2018 Oct 27.

PMID:
30229860
8.

High-throughput combinatorial screening reveals interactions between signaling molecules that regulate adult neural stem cell fate.

Muckom R, McFarland S, Yang C, Perea B, Gentes M, Murugappan A, Tran E, Dordick JS, Clark DS, Schaffer DV.

Biotechnol Bioeng. 2019 Jan;116(1):193-205. doi: 10.1002/bit.26815. Epub 2018 Nov 6.

PMID:
30102775
9.

Rayleigh-Taylor instabilities in high-energy density settings on the National Ignition Facility.

Remington BA, Park HS, Casey DT, Cavallo RM, Clark DS, Huntington CM, Kuranz CC, Miles AR, Nagel SR, Raman KS, Smalyuk VA.

Proc Natl Acad Sci U S A. 2018 Jun 26. pii: 201717236. doi: 10.1073/pnas.1717236115. [Epub ahead of print]

PMID:
29946021
10.

Controlled Assembly of the Filamentous Chaperone Gamma-Prefoldin into Defined Nanostructures.

Clark DS, Glover DJ.

Methods Mol Biol. 2018;1798:293-306. doi: 10.1007/978-1-4939-7893-9_22.

PMID:
29868968
11.

Severity and Features of Epistaxis in Children with a Mucocutaneous Bleeding Disorder.

Stokhuijzen E, Segbefia CI, Biss TT, Clark DS, James PD, Riddel J, Blanchette VS, Rand ML.

J Pediatr. 2018 Feb;193:183-189.e2. doi: 10.1016/j.jpeds.2017.09.082. Epub 2017 Dec 1.

PMID:
29198540
12.

Publisher's Note: X-ray shadow imprint of hydrodynamic instabilities on the surface of inertial confinement fusion capsules by the fuel fill tube [Phys. Rev. E 95, 031204(R) (2017)].

MacPhee AG, Casey DT, Clark DS, Felker S, Field JE, Haan SW, Hammel BA, Kroll J, Landen OL, Martinez DA, Michel P, Milovich J, Moore A, Nikroo A, Rice N, Robey HF, Smalyuk VA, Stadermann M, Weber CR.

Phys Rev E. 2017 Jun;95(6-2):069905. doi: 10.1103/PhysRevE.95.069905. Epub 2017 Jun 27.

PMID:
28709236
13.

Beyond Iron: Iridium-Containing P450 Enzymes for Selective Cyclopropanations of Structurally Diverse Alkenes.

Key HM, Dydio P, Liu Z, Rha JY, Nazarenko A, Seyedkazemi V, Clark DS, Hartwig JF.

ACS Cent Sci. 2017 Apr 26;3(4):302-308. doi: 10.1021/acscentsci.6b00391. Epub 2017 Apr 1.

14.

X-ray shadow imprint of hydrodynamic instabilities on the surface of inertial confinement fusion capsules by the fuel fill tube.

MacPhee AG, Casey DT, Clark DS, Felker S, Field JE, Haan SW, Hammel BA, Kroll J, Landen OL, Martinez DA, Michel P, Milovich J, Moore A, Nikroo A, Rice N, Robey HF, Smalyuk VA, Stadermann M, Weber CR.

Phys Rev E. 2017 Mar;95(3-1):031204. doi: 10.1103/PhysRevE.95.031204. Epub 2017 Mar 30. Erratum in: Phys Rev E. 2017 Jun;95(6-2):069905.

PMID:
28415208
15.

High-Throughput Toxicity and Phenotypic Screening of 3D Human Neural Progenitor Cell Cultures on a Microarray Chip Platform.

Nierode GJ, Perea BC, McFarland SK, Pascoal JF, Clark DS, Schaffer DV, Dordick JS.

Stem Cell Reports. 2016 Nov 8;7(5):970-982. doi: 10.1016/j.stemcr.2016.10.001. Epub 2016 Oct 27.

16.

Identification of Glutaminyl Cyclase Genes Involved in Pyroglutamate Modification of Fungal Lignocellulolytic Enzymes.

Wu VW, Dana CM, Iavarone AT, Clark DS, Glass NL.

MBio. 2017 Jan 17;8(1). pii: e02231-16. doi: 10.1128/mBio.02231-16.

17.

Chemoselective, Enzymatic C-H Bond Amination Catalyzed by a Cytochrome P450 Containing an Ir(Me)-PIX Cofactor.

Dydio P, Key HM, Hayashi H, Clark DS, Hartwig JF.

J Am Chem Soc. 2017 Feb 8;139(5):1750-1753. doi: 10.1021/jacs.6b11410. Epub 2017 Jan 26.

18.

An artificial metalloenzyme with the kinetics of native enzymes.

Dydio P, Key HM, Nazarenko A, Rha JY, Seyedkazemi V, Clark DS, Hartwig JF.

Science. 2016 Oct 7;354(6308):102-106.

PMID:
27846500
19.

Protein Calligraphy: A New Concept Begins To Take Shape.

Glover DJ, Clark DS.

ACS Cent Sci. 2016 Jul 27;2(7):438-44. doi: 10.1021/acscentsci.6b00067. Epub 2016 Jun 7. Review.

20.

Abiological catalysis by artificial haem proteins containing noble metals in place of iron.

Key HM, Dydio P, Clark DS, Hartwig JF.

Nature. 2016 Jun 23;534(7608):534-7. doi: 10.1038/nature17968. Epub 2016 Jun 13.

21.

Geometrical assembly of ultrastable protein templates for nanomaterials.

Glover DJ, Giger L, Kim SS, Naik RR, Clark DS.

Nat Commun. 2016 Jun 1;7:11771. doi: 10.1038/ncomms11771.

22.

Co-production of acetone and ethanol with molar ratio control enables production of improved gasoline or jet fuel blends.

Baer ZC, Bormann S, Sreekumar S, Grippo A, Toste FD, Blanch HW, Clark DS.

Biotechnol Bioeng. 2016 Oct;113(10):2079-87. doi: 10.1002/bit.25978. Epub 2016 Mar 31.

23.

Engineering ionic liquid-tolerant cellulases for biofuels production.

Wolski PW, Dana CM, Clark DS, Blanch HW.

Protein Eng Des Sel. 2016 Apr;29(4):117-22. doi: 10.1093/protein/gzv066. Epub 2016 Jan 26.

PMID:
26819239
24.

Simultaneous selection and counter-selection for the directed evolution of proteases in E. coli using a cytoplasmic anchoring strategy.

Carrico ZM, Strobel KL, Atreya ME, Clark DS, Francis MB.

Biotechnol Bioeng. 2016 Jun;113(6):1187-93. doi: 10.1002/bit.25904. Epub 2015 Dec 31.

PMID:
26666461
25.

Engineering Cel7A carbohydrate binding module and linker for reduced lignin inhibition.

Strobel KL, Pfeiffer KA, Blanch HW, Clark DS.

Biotechnol Bioeng. 2016 Jun;113(6):1369-74. doi: 10.1002/bit.25889. Epub 2015 Dec 8.

PMID:
26616493
26.

Improved Performance of High Areal Density Indirect Drive Implosions at the National Ignition Facility using a Four-Shock Adiabat Shaped Drive.

Casey DT, Milovich JL, Smalyuk VA, Clark DS, Robey HF, Pak A, MacPhee AG, Baker KL, Weber CR, Ma T, Park HS, Döppner T, Callahan DA, Haan SW, Patel PK, Peterson JL, Hoover D, Nikroo A, Yeamans CB, Merrill FE, Volegov PL, Fittinghoff DN, Grim GP, Edwards MJ, Landen OL, Lafortune KN, MacGowan BJ, Widmayer CC, Sayre DB, Hatarik R, Bond EJ, Nagel SR, Benedetti LR, Izumi N, Khan S, Bachmann B, Spears BK, Cerjan CJ, Gatu Johnson M, Frenje JA.

Phys Rev Lett. 2015 Sep 4;115(10):105001. Epub 2015 Sep 1.

PMID:
26382681
27.

Alleviating product inhibition in cellulase enzyme Cel7A.

Atreya ME, Strobel KL, Clark DS.

Biotechnol Bioeng. 2016 Feb;113(2):330-8. doi: 10.1002/bit.25809. Epub 2015 Sep 10.

28.

Structural insights into the affinity of Cel7A carbohydrate-binding module for lignin.

Strobel KL, Pfeiffer KA, Blanch HW, Clark DS.

J Biol Chem. 2015 Sep 11;290(37):22818-26. doi: 10.1074/jbc.M115.673467. Epub 2015 Jul 24.

29.

Oligomeric assembly is required for chaperone activity of the filamentous γ-prefoldin.

Glover DJ, Clark DS.

FEBS J. 2015 Aug;282(15):2985-97. doi: 10.1111/febs.13341. Epub 2015 Jul 2.

30.

Generation, Characterization, and Tunable Reactivity of Organometallic Fragments Bound to a Protein Ligand.

Key HM, Clark DS, Hartwig JF.

J Am Chem Soc. 2015 Jul 1;137(25):8261-8. doi: 10.1021/jacs.5b04431. Epub 2015 Jun 23.

31.

Evaluating endoglucanase Cel7B-lignin interaction mechanisms and kinetics using quartz crystal microgravimetry.

Pfeiffer KA, Sorek H, Roche CM, Strobel KL, Blanch HW, Clark DS.

Biotechnol Bioeng. 2015 Nov;112(11):2256-66. doi: 10.1002/bit.25657. Epub 2015 Jul 14.

PMID:
25994114
32.

Mutagenesis of Trichoderma reesei endoglucanase I: impact of expression host on activity and stability at elevated temperatures.

Chokhawala HA, Roche CM, Kim TW, Atreya ME, Vegesna N, Dana CM, Blanch HW, Clark DS.

BMC Biotechnol. 2015 Feb 21;15:11. doi: 10.1186/s12896-015-0118-z.

33.

Differential ablator-fuel adiabat tuning in indirect-drive implosions.

Peterson JL, Berzak Hopkins LF, Jones OS, Clark DS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Mar;91(3):031101. Epub 2015 Mar 9.

PMID:
25871043
34.

Production of an acetone-butanol-ethanol mixture from Clostridium acetobutylicum and its conversion to high-value biofuels.

Sreekumar S, Baer ZC, Pazhamalai A, Gunbas G, Grippo A, Blanch HW, Clark DS, Toste FD.

Nat Protoc. 2015 Mar;10(3):528-37. doi: 10.1038/nprot.2015.029. Epub 2015 Feb 26.

PMID:
25719271
35.

Klaus Mosbach tribute.

Clark DS, Karube I, Sode K, Bülow L, Brüggemann O, Lowe CR, Poulsen PB, Langer RS.

Biotechnol Bioeng. 2015 Apr;112(4):645-7. doi: 10.1002/bit.25507. Epub 2015 Jan 20. No abstract available.

PMID:
25599981
36.

Inhibition of turbulence in inertial-confinement-fusion hot spots by viscous dissipation.

Weber CR, Clark DS, Cook AW, Busby LE, Robey HF.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 May;89(5):053106. Epub 2014 May 27.

PMID:
25353903
37.

Normal range of bleeding scores for the ISTH-BAT: adult and pediatric data from the merging project.

Elbatarny M, Mollah S, Grabell J, Bae S, Deforest M, Tuttle A, Hopman W, Clark DS, Mauer AC, Bowman M, Riddel J, Christopherson PA, Montgomery RR; Zimmerman Program Investigators, Rand ML, Coller B, James PD.

Haemophilia. 2014 Nov;20(6):831-5. doi: 10.1111/hae.12503. Epub 2014 Sep 6.

38.

Reduced instability growth with high-adiabat high-foot implosions at the National Ignition Facility.

Casey DT, Smalyuk VA, Raman KS, Peterson JL, Berzak Hopkins L, Callahan DA, Clark DS, Dewald EL, Dittrich TR, Haan SW, Hinkel DE, Hoover D, Hurricane OA, Kroll JJ, Landen OL, Moore AS, Nikroo A, Park HS, Remington BA, Robey HF, Rygg JR, Salmonson JD, Tommasini R, Widmann K.

Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Jul;90(1):011102. Epub 2014 Jul 25.

PMID:
25122242
39.

Engineering Clostridium acetobutylicum for production of kerosene and diesel blendstock precursors.

Bormann S, Baer ZC, Sreekumar S, Kuchenreuther JM, Dean Toste F, Blanch HW, Clark DS.

Metab Eng. 2014 Sep;25:124-30. doi: 10.1016/j.ymben.2014.07.003. Epub 2014 Jul 18.

PMID:
25046159
40.

Chemocatalytic upgrading of tailored fermentation products toward biodiesel.

Sreekumar S, Baer ZC, Gross E, Padmanaban S, Goulas K, Gunbas G, Alayoglu S, Blanch HW, Clark DS, Toste FD.

ChemSusChem. 2014 Sep;7(9):2445-8. doi: 10.1002/cssc.201402244. Epub 2014 Jul 15.

PMID:
25044817
41.

First measurements of hydrodynamic instability growth in indirectly driven implosions at ignition-relevant conditions on the National Ignition Facility.

Smalyuk VA, Casey DT, Clark DS, Edwards MJ, Haan SW, Hamza A, Hoover DE, Hsing WW, Hurricane O, Kilkenny JD, Kroll J, Landen OL, Moore A, Nikroo A, Peterson L, Raman K, Remington BA, Robey HF, Weber SV, Widmann K.

Phys Rev Lett. 2014 May 9;112(18):185003. Epub 2014 May 8.

PMID:
24856703
42.

High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening.

Kwon SJ, Lee DW, Shah DA, Ku B, Jeon SY, Solanki K, Ryan JD, Clark DS, Dordick JS, Lee MY.

Nat Commun. 2014 May 6;5:3739. doi: 10.1038/ncomms4739.

43.

Identification of novel biomass-degrading enzymes from genomic dark matter: Populating genomic sequence space with functional annotation.

Piao H, Froula J, Du C, Kim TW, Hawley ER, Bauer S, Wang Z, Ivanova N, Clark DS, Klenk HP, Hess M.

Biotechnol Bioeng. 2014 Aug;111(8):1550-65. doi: 10.1002/bit.25250. Epub 2014 May 28.

PMID:
24728961
44.

Engineering the filamentous fungus Neurospora crassa for lipid production from lignocellulosic biomass.

Roche CM, Glass NL, Blanch HW, Clark DS.

Biotechnol Bioeng. 2014 Jun;111(6):1097-107. doi: 10.1002/bit.25211. Epub 2014 Apr 3.

PMID:
24700367
45.

Measurements of an ablator-gas atomic mix in indirectly driven implosions at the National Ignition Facility.

Smalyuk VA, Tipton RE, Pino JE, Casey DT, Grim GP, Remington BA, Rowley DP, Weber SV, Barrios M, Benedetti LR, Bleuel DL, Bradley DK, Caggiano JA, Callahan DA, Cerjan CJ, Clark DS, Edgell DH, Edwards MJ, Frenje JA, Gatu-Johnson M, Glebov VY, Glenn S, Haan SW, Hamza A, Hatarik R, Hsing WW, Izumi N, Khan S, Kilkenny JD, Kline J, Knauer J, Landen OL, Ma T, McNaney JM, Mintz M, Moore A, Nikroo A, Pak A, Parham T, Petrasso R, Sayre DB, Schneider MB, Tommasini R, Town RP, Widmann K, Wilson DC, Yeamans CB.

Phys Rev Lett. 2014 Jan 17;112(2):025002. Epub 2014 Jan 14.

PMID:
24484021
46.

The importance of pyroglutamate in cellulase Cel7A.

Dana CM, Dotson-Fagerstrom A, Roche CM, Kal SM, Chokhawala HA, Blanch HW, Clark DS.

Biotechnol Bioeng. 2014 Apr;111(4):842-7. doi: 10.1002/bit.25178. Epub 2014 Jan 28.

PMID:
24375151
47.

Onset of hydrodynamic mix in high-velocity, highly compressed inertial confinement fusion implosions.

Ma T, Patel PK, Izumi N, Springer PT, Key MH, Atherton LJ, Benedetti LR, Bradley DK, Callahan DA, Celliers PM, Cerjan CJ, Clark DS, Dewald EL, Dixit SN, Döppner T, Edgell DH, Epstein R, Glenn S, Grim G, Haan SW, Hammel BA, Hicks D, Hsing WW, Jones OS, Khan SF, Kilkenny JD, Kline JL, Kyrala GA, Landen OL, Le Pape S, MacGowan BJ, Mackinnon AJ, MacPhee AG, Meezan NB, Moody JD, Pak A, Parham T, Park HS, Ralph JE, Regan SP, Remington BA, Robey HF, Ross JS, Spears BK, Smalyuk V, Suter LJ, Tommasini R, Town RP, Weber SV, Lindl JD, Edwards MJ, Glenzer SH, Moses EI.

Phys Rev Lett. 2013 Aug 23;111(8):085004. Epub 2013 Aug 23.

PMID:
24010449
48.

Cardiovascular disease in women: peripheral artery disease.

Clark DS.

FP Essent. 2013 Aug;411:23-7. Erratum in: FP Essent. 2014 Aug;423:44.

PMID:
23977828
49.

Physiological role of Acyl coenzyme A synthetase homologs in lipid metabolism in Neurospora crassa.

Roche CM, Blanch HW, Clark DS, Glass NL.

Eukaryot Cell. 2013 Sep;12(9):1244-57. doi: 10.1128/EC.00079-13. Epub 2013 Jul 19.

50.

Refraction-enhanced backlit imaging of axially symmetric inertial confinement fusion plasmas.

Koch JA, Landen OL, Suter LJ, Masse LP, Clark DS, Ross JS, Mackinnon AJ, Meezan NB, Thomas CA, Ping Y.

Appl Opt. 2013 May 20;52(15):3538-56. doi: 10.1364/AO.52.003538.

PMID:
23736240

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