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Photon-counting cine-cardiac CT in the mouse.

Clark DP, Holbrook M, Lee CL, Badea CT.

PLoS One. 2019 Sep 19;14(9):e0218417. doi: 10.1371/journal.pone.0218417. eCollection 2019.


Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019.

Donaldson K, Buchanich JM, Grigson PS, Deneke E, Donaldson K, Vrana KE, Sacks DB, Kuehn GJ, Cardamone D, Pesce A, Smiley S, Nickley J, Krock K, Thomas R, Wilkerson ML, Farag HA, Challa SR, Tice AM, Wolk DM, Prichard J, Grant ML, Regmi S, Kerbacher B, Quinton LE, Farag HA, Tice AM, Wolk DM, Olson J, Haynes A, Yu E, McCully KS, Assi J, Wong M, Zarrin-Khameh N, Nifong TP, Hawker CD, Carlton GT, Rivera JM, Foulis PR, Zuraw A, Morlote D, Peker D, Reddy V, Harada S, Crutchfield C, Zander D, Barbhuiya MA, Pederson EC, Straub ML, Scott SC, Neibauer TL, Salter WF, Creer MH, Zhu Y, Bornhorst JA, Theobald JP, Algeciras-Schimnich A, Cao L, Knox J, Hardy R, Texas HJ, McGuire MF, Hunter RL, Brown RE, Hicks J, Hicks J, Cai Z, Brown RE, Ali Y, Cheng KC, Katz SR, Ding Y, Vanselow DJ, Yakovlev MA, Lin AY, Clark DP, Vargas P, Xin X, Copper JE, Canfield VA, Ang KC, Wang Y, Xiao X, De Carlo F, van Rossum DB, La Rivière PJ, Newell J, Hossler C, Roche M, Warrick J, Phaeton R, Kesterson J, Donaldson K, Myers C, Barrios R, Mintz P, Robyak K, Hamilton C, McGhee P, Pederson C, Straub M, Scott S, Neibauer T, Salter W, Creer M, Zhu Y, Hamilton C, Robyak K, McGhee P, Pederson C, Straub M, Scott S, Neibauer T, Salter W, Creer M, Zhu Y, Singh N, Morlote D, Vnencak-Jones C, Yemelyanova A, Harada S, Shah M, Moghadamtousi SZ, Lan C, Duose D, Hu P, Esquenazi Y, Luthra R, Ballester LY, Koenig AN, Liu CG, Zhang J, Kalia A, Al-Habib A, Van Arsdall M, Dhingra S, Patel K, Tatevian N.

Ann Clin Lab Sci. 2019 May;49(3):403-416. No abstract available.


A Deep Learning Convolutional Neural Network Can Recognize Common Patterns of Injury in Gastric Pathology.

Martin DR, Hanson JA, Gullapalli RR, Schultz FA, Sethi A, Clark DP.

Arch Pathol Lab Med. 2019 Jun 27. doi: 10.5858/arpa.2019-0004-OA. [Epub ahead of print]


Computational 3D histological phenotyping of whole zebrafish by X-ray histotomography.

Ding Y, Vanselow DJ, Yakovlev MA, Katz SR, Lin AY, Clark DP, Vargas P, Xin X, Copper JE, Canfield VA, Ang KC, Wang Y, Xiao X, De Carlo F, van Rossum DB, La Riviere P, Cheng KC.

Elife. 2019 May 7;8. pii: e44898. doi: 10.7554/eLife.44898.


Overcoming detector limitations of x-ray photon counting for preclinical microcomputed tomography.

Holbrook M, Clark DP, Badea CT.

J Med Imaging (Bellingham). 2019 Jan;6(1):011004. doi: 10.1117/1.JMI.6.1.011004. Epub 2018 Aug 24.


Functional imaging of tumor vasculature using iodine and gadolinium-based nanoparticle contrast agents: a comparison of spectral micro-CT using energy integrating and photon counting detectors.

Badea CT, Clark DP, Holbrook M, Srivastava M, Mowery Y, Ghaghada KB.

Phys Med Biol. 2019 Mar 12;64(6):065007. doi: 10.1088/1361-6560/ab03e2.


Inflammation in Traumatic Brain Injury: Roles for Toxic A1 Astrocytes and Microglial-Astrocytic Crosstalk.

Clark DPQ, Perreau VM, Shultz SR, Brady RD, Lei E, Dixit S, Taylor JM, Beart PM, Boon WC.

Neurochem Res. 2019 Jun;44(6):1410-1424. doi: 10.1007/s11064-019-02721-8. Epub 2019 Jan 19.


Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography.

Lin AY, Ding Y, Vanselow DJ, Katz SR, Yakovlev MA, Clark DP, Mandrell D, Copper JE, van Rossum DB, Cheng KC.

J Vis Exp. 2018 Oct 17;(140). doi: 10.3791/58293.


Ancillary studies in cytology: Secondary or necessary?

Clark DP.

Cancer Cytopathol. 2018 Aug;126 Suppl 8:584-589. doi: 10.1002/cncy.22011. Review.


Comparative analysis of fixation and embedding techniques for optimized histological preparation of zebrafish.

Copper JE, Budgeon LR, Foutz CA, van Rossum DB, Vanselow DJ, Hubley MJ, Clark DP, Mandrell DT, Cheng KC.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Jun;208:38-46. doi: 10.1016/j.cbpc.2017.11.003. Epub 2017 Nov 20.


Low-dose 4D cardiac imaging in small animals using dual source micro-CT.

Holbrook M, Clark DP, Badea CT.

Phys Med Biol. 2018 Jan 9;63(2):025009. doi: 10.1088/1361-6560/aa9b45.


Biomarkers for immune checkpoint inhibitors: The importance of tumor topography and the challenges to cytopathology.

Clark DP.

Cancer Cytopathol. 2018 Jan;126(1):11-19. doi: 10.1002/cncy.21951. Epub 2017 Nov 13. Review.


Hybrid spectral CT reconstruction.

Clark DP, Badea CT.

PLoS One. 2017 Jul 6;12(7):e0180324. doi: 10.1371/journal.pone.0180324. eCollection 2017.


A neural network-based method for spectral distortion correction in photon counting x-ray CT.

Touch M, Clark DP, Barber W, Badea CT.

Phys Med Biol. 2016 Aug 21;61(16):6132-53. doi: 10.1088/0031-9155/61/16/6132. Epub 2016 Jul 29.


Spectrotemporal CT data acquisition and reconstruction at low dose.

Clark DP, Lee CL, Kirsch DG, Badea CT.

Med Phys. 2015 Nov;42(11):6317-36. doi: 10.1118/1.4931407.


Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer.

Ball DW, Jin N, Xue P, Bhan S, Ahmed SR, Rosen DM, Schayowitz A, Clark DP, Nelkin BD.

Oncol Rep. 2015 Nov;34(5):2319-24. doi: 10.3892/or.2015.4225. Epub 2015 Aug 26.


Fit to last: Exploring the longevity of the survival processing effect.

Clark DP, Bruno D.

Q J Exp Psychol (Hove). 2016;69(6):1164-78. doi: 10.1080/17470218.2015.1076864. Epub 2015 Sep 4.


Spectral diffusion: an algorithm for robust material decomposition of spectral CT data.

Clark DP, Badea CT.

Phys Med Biol. 2014 Nov 7;59(21):6445-66. doi: 10.1088/0031-9155/59/21/6445. Epub 2014 Oct 8.


Micro-CT of rodents: state-of-the-art and future perspectives.

Clark DP, Badea CT.

Phys Med. 2014 Sep;30(6):619-34. doi: 10.1016/j.ejmp.2014.05.011. Epub 2014 Jun 26. Review.


Economic impact of converting an interventional pain medicine physician office-based practice into a provider-based ambulatory pain practice.

Grider JS, Findley KA, Higdon C, Curtright J, Clark DP.

Pain Physician. 2014 May-Jun;17(3):E253-61.


Benefits of phoneme discrimination training in a randomized controlled trial of 50- to 74-year-olds with mild hearing loss.

Ferguson MA, Henshaw H, Clark DP, Moore DR.

Ear Hear. 2014 Jul-Aug;35(4):e110-21. doi: 10.1097/AUD.0000000000000020.


Dual-energy micro-CT functional imaging of primary lung cancer in mice using gold and iodine nanoparticle contrast agents: a validation study.

Ashton JR, Clark DP, Moding EJ, Ghaghada K, Kirsch DG, West JL, Badea CT.

PLoS One. 2014 Feb 10;9(2):e88129. doi: 10.1371/journal.pone.0088129. eCollection 2014.


Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.

Xing M, Alzahrani AS, Carson KA, Viola D, Elisei R, Bendlova B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L, Czarniecka A, Jarzab B, O'Neill CJ, Sywak MS, Lam AK, Riesco-Eizaguirre G, Santisteban P, Nakayama H, Tufano RP, Pai SI, Zeiger MA, Westra WH, Clark DP, Clifton-Bligh R, Sidransky D, Ladenson PW, Sykorova V.

JAMA. 2013 Apr 10;309(14):1493-501. doi: 10.1001/jama.2013.3190.


In vivo characterization of tumor vasculature using iodine and gold nanoparticles and dual energy micro-CT.

Clark DP, Ghaghada K, Moding EJ, Kirsch DG, Badea CT.

Phys Med Biol. 2013 Mar 21;58(6):1683-704. doi: 10.1088/0031-9155/58/6/1683. Epub 2013 Feb 19.


Functional profiling of live melanoma samples using a novel automated platform.

Schayowitz A, Bertenshaw G, Jeffries E, Schatz T, Cotton J, Villanueva J, Herlyn M, Krepler C, Vultur A, Xu W, Yu GH, Schuchter L, Clark DP.

PLoS One. 2012;7(12):e52760. doi: 10.1371/journal.pone.0052760. Epub 2012 Dec 28.


Testing the exclusivity effect in location memory.

Clark DP, Dunn AK, Baguley T.

Memory. 2013;21(4):512-23. doi: 10.1080/09658211.2012.744421. Epub 2012 Dec 3. Erratum in: Memory. 2015;23(5):795.


Dual-energy micro-computed tomography imaging of radiation-induced vascular changes in primary mouse sarcomas.

Moding EJ, Clark DP, Qi Y, Li Y, Ma Y, Ghaghada K, Johnson GA, Kirsch DG, Badea CT.

Int J Radiat Oncol Biol Phys. 2013 Apr 1;85(5):1353-9. doi: 10.1016/j.ijrobp.2012.09.027. Epub 2012 Nov 1.


Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties.

Henshaw H, Clark DP, Kang S, Ferguson MA.

J Med Internet Res. 2012 Aug 24;14(4):e113. doi: 10.2196/jmir.2036.


Practice patterns in cervical cancer screening and human papillomavirus testing.

Tatsas AD, Phelan DF, Gravitt PE, Boitnott JK, Clark DP.

Am J Clin Pathol. 2012 Aug;138(2):223-9. doi: 10.1309/AJCPPVX91HQMNYZZ.


Three-gene molecular diagnostic model for thyroid cancer.

Prasad NB, Kowalski J, Tsai HL, Talbot K, Somervell H, Kouniavsky G, Wang Y, Dackiw AP, Westra WH, Clark DP, Libutti SK, Umbricht CB, Zeiger MA.

Thyroid. 2012 Mar;22(3):275-84. doi: 10.1089/thy.2011.0169. Epub 2012 Jan 26.


Spectrum of risk of malignancy in subcategories of 'atypia of undetermined significance'.

Olson MT, Clark DP, Erozan YS, Ali SZ.

Acta Cytol. 2011;55(6):518-25. doi: 10.1159/000333232. Epub 2011 Dec 9.


Improvement of cellularity on cell block preparations using the so-called tissue coagulum clot method during endobronchial ultrasound-guided transbronchial fine-needle aspiration.

Yung RC, Otell S, Illei P, Clark DP, Feller-Kopman D, Yarmus L, Askin F, Gabrielson E, Li QK.

Cancer Cytopathol. 2012 Jun 25;120(3):185-95. doi: 10.1002/cncy.20199. Epub 2011 Dec 5.


Whole-animal imaging, gene function, and the Zebrafish Phenome Project.

Cheng KC, Xin X, Clark DP, La Riviere P.

Curr Opin Genet Dev. 2011 Oct;21(5):620-9. doi: 10.1016/j.gde.2011.08.006. Epub 2011 Sep 28. Review.


Associations between oral HPV16 infection and cytopathology: evaluation of an oropharyngeal "pap-test equivalent" in high-risk populations.

Fakhry C, Rosenthal BT, Clark DP, Gillison ML.

Cancer Prev Res (Phila). 2011 Sep;4(9):1378-84. doi: 10.1158/1940-6207.CAPR-11-0284. Epub 2011 Aug 11.


Biospecimen Reporting for Improved Study Quality.

Moore HM, Kelly A, Jewell SD, McShane LM, Clark DP, Greenspan R, Hainaut P, Hayes DF, Kim P, Mansfield E, Potapova O, Riegman P, Rubinstein Y, Seijo E, Somiari S, Watson P, Weier HU, Zhu C, Vaught J.

Biopreserv Biobank. 2011 Apr;9(1):57-70.


Trends of human papillomavirus testing in cervical cancer screening at a large academic cytology laboratory.

Phelan DF, Boitnott JK, Clark DP, Dubay LC, Gravitt PE.

Obstet Gynecol. 2011 Aug;118(2 Pt 1):289-95. doi: 10.1097/AOG.0b013e3182253c33.


Biospecimen reporting for improved study quality (BRISQ).

Moore HM, Kelly AB, Jewell SD, McShane LM, Clark DP, Greenspan R, Hayes DF, Hainaut P, Kim P, Mansfield E, Potapova O, Riegman P, Rubinstein Y, Seijo E, Somiari S, Watson P, Weier HU, Zhu C, Vaught J.

J Proteome Res. 2011 Aug 5;10(8):3429-38. doi: 10.1021/pr200021n. Epub 2011 Jun 21.


Biospecimen reporting for improved study quality (BRISQ).

Moore HM, Kelly AB, Jewell SD, McShane LM, Clark DP, Greenspan R, Hayes DF, Hainaut P, Kim P, Mansfield EA, Potapova O, Riegman P, Rubinstein Y, Seijo E, Somiari S, Watson P, Weier HU, Zhu C, Vaught J.

Cancer Cytopathol. 2011 Apr 25;119(2):92-101. doi: 10.1002/cncy.20147. Epub 2011 Mar 22.


The utility of napsin-A in the identification of primary and metastatic lung adenocarcinoma among cytologically poorly differentiated carcinomas.

Stoll LM, Johnson MW, Gabrielson E, Askin F, Clark DP, Li QK.

Cancer Cytopathol. 2010 Dec 25;118(6):441-9. doi: 10.1002/cncy.20108. Epub 2010 Sep 9.


Cytology of endobronchial ultrasound-guided transbronchial needle aspiration versus conventional transbronchial needle aspiration.

Stoll LM, Yung RC, Clark DP, Li QK.

Cancer Cytopathol. 2010 Oct 25;118(5):278-86. doi: 10.1002/cncy.20103.


NKX3.1 as a marker of prostatic origin in metastatic tumors.

Gurel B, Ali TZ, Montgomery EA, Begum S, Hicks J, Goggins M, Eberhart CG, Clark DP, Bieberich CJ, Epstein JI, De Marzo AM.

Am J Surg Pathol. 2010 Aug;34(8):1097-105. doi: 10.1097/PAS.0b013e3181e6cbf3.


Analysis of nondiagnostic results after image-guided needle biopsies of musculoskeletal lesions.

Yang J, Frassica FJ, Fayad L, Clark DP, Weber KL.

Clin Orthop Relat Res. 2010 Nov;468(11):3103-11. doi: 10.1007/s11999-010-1337-1. Epub 2010 Apr 10.


Fluorescence in situ hybridization in the definitive diagnosis of malignant mesothelioma in effusion cytology.

Savic S, Franco N, Grilli B, Barascud Ade V, Herzog M, Bode B, Loosli H, Spieler P, Schönegg R, Zlobec I, Clark DP, Herman JG, Bubendorf L.

Chest. 2010 Jul;138(1):137-44. doi: 10.1378/chest.09-1951. Epub 2010 Feb 5.


Molecular diagnostics on thyroid fine-needle aspirations: the pathway to value creation.

Clark DP.

Cancer Cytopathol. 2010 Feb 25;118(1):14-6. doi: 10.1002/cncy.20064. No abstract available.


Accurate classification of non-small cell lung carcinoma using a novel microRNA-based approach.

Bishop JA, Benjamin H, Cholakh H, Chajut A, Clark DP, Westra WH.

Clin Cancer Res. 2010 Jan 15;16(2):610-9. doi: 10.1158/1078-0432.CCR-09-2638. Epub 2010 Jan 12.


Ex vivo biomarkers: functional tools to guide targeted drug development and therapy.

Clark DP.

Expert Rev Mol Diagn. 2009 Nov;9(8):787-94. doi: 10.1586/erm.09.62.


Seize the opportunity: underutilization of fine-needle aspiration biopsy to inform targeted cancer therapy decisions.

Clark DP.

Cancer. 2009 Oct 25;117(5):289-97. doi: 10.1002/cncy.20045. Review. No abstract available.


An unusual case of recurrent hyperparathyroidism and papillary thyroid cancer.

Morita SY, Brownlee NA, Dackiw AP, Westra WH, Clark DP, Zeiger MA.

Endocr Pract. 2009 May-Jun;15(4):349-52. doi: 10.4158/EP08145.CRR1.


The use of botulinum toxin in the treatment of a parotid duct injury during Mohs surgery and review of management options.

Krishnan RS, Clark DP, Donnelly HB.

Dermatol Surg. 2009 Jun;35(6):941-7. doi: 10.1111/j.1524-4725.2009.01159.x. Epub 2009 Apr 8.


A diagnostic predictor model for indeterminate or suspicious thyroid FNA samples.

Banks ND, Kowalski J, Tsai HL, Somervell H, Tufano R, Dackiw AP, Marohn MR, Clark DP, Umbricht CB, Zeiger MA.

Thyroid. 2008 Sep;18(9):933-41. doi: 10.1089/thy.2008.0108.


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