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Prevalence of Obstructive Sleep Apnea in Patients with Thoracic Aortic Aneurysm: A Prospective, Parallel Cohort Study.

Gaisl T, Baumgartner P, Rejmer P, Osswald M, Roeder M, Thiel S, Stämpfli SF, Clarenbach CF, Tanner FC, Kohler M.

Respiration. 2019 Sep 25:1-9. doi: 10.1159/000502892. [Epub ahead of print]


Obstructive sleep apnea and quality of life in Fabry disease: a prospective parallel cohort study.

Gaisl T, Nowak A, Sievi NA, Gerard N, Clarenbach CF, Kohler M, Franzen D.

Sleep Breath. 2019 Apr 2. doi: 10.1007/s11325-019-01832-4. [Epub ahead of print]


No impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation.

Sievi NA, Kohler M, Thurnheer R, Leuppi JD, Irani S, Frey M, Brutsche M, Brack T, Clarenbach CF.

Int J Chron Obstruct Pulmon Dis. 2019 Feb 15;14:431-437. doi: 10.2147/COPD.S188710. eCollection 2019.


The Swiss Primary Ciliary Dyskinesia registry: objectives, methods and first results

Goutaki M, Eich MO, Halbeisen FS, Barben J, Casaulta C, Clarenbach C, Hafen G, Latzin P, Regamey N, Lazor R, Tschanz S, Zanolari M, Maurer E, Kuehni CE; Swiss PCD Registry (CH-PCD) Working Group.

Swiss Med Wkly. 2019 Jan 13;149. pii: w20004. doi: 10.4414/smw.2019.20004. eCollection 2019 Jan 1.


Diagnosis, Prevention and Treatment of Stable COPD and Acute Exacerbations of COPD: The Swiss Recommendations 2018.

Stolz D, Barandun J, Borer H, Bridevaux PO, Brun P, Brutsche M, Clarenbach C, Eich C, Fiechter R, Frey M, Geiser T, Grob M, Helfenstein E, Junker L, Kohler M, Latshang T, Lechmann A, Maurer M, Nicod L, Quadri F, Schilter D, Sigrist T, Soccal P, Tarr P, Thurnheer R, Turk A, Tamm M.

Respiration. 2018;96(4):382-398. doi: 10.1159/000490551. Epub 2018 Aug 23.


Physical activity declines in COPD while exercise capacity remains stable: A longitudinal study over 5 years.

Sievi NA, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Kohler M, Clarenbach CF.

Respir Med. 2018 Aug;141:1-6. doi: 10.1016/j.rmed.2018.06.013. Epub 2018 Jun 18.


Lung volume reduction surgery does not increase daily physical activity in patients with severe chronic obstructive pulmonary disease.

Sievi NA, Franzen D, Kohler M, Clarenbach CF.

J Thorac Dis. 2018 May;10(5):2722-2730. doi: 10.21037/jtd.2018.05.18.


Diagnosis and Management of Asthma - The Swiss Guidelines.

Rothe T, Spagnolo P, Bridevaux PO, Clarenbach C, Eich-Wanger C, Meyer F, Miedinger D, Möller A, Nicod LP, Nicolet-Chatelain G, Sauty A, Steurer-Stey C, Leuppi JD.

Respiration. 2018;95(5):364-380. doi: 10.1159/000486797. Epub 2018 Apr 3.


Annual progression of endothelial dysfunction in patients with COPD.

Clarenbach CF, Sievi NA, Kohler M.

Respir Med. 2017 Nov;132:15-20. doi: 10.1016/j.rmed.2017.09.005. Epub 2017 Sep 18.


Ipilimumab and early signs of pulmonary toxicity in patients with metastastic melanoma: a prospective observational study.

Franzen D, Schad K, Kowalski B, Clarenbach CF, Stupp R, Dummer R, Kohler M.

Cancer Immunol Immunother. 2018 Jan;67(1):127-134. doi: 10.1007/s00262-017-2071-2. Epub 2017 Oct 5.


Physical activity patterns and clusters in 1001 patients with COPD.

Mesquita R, Spina G, Pitta F, Donaire-Gonzalez D, Deering BM, Patel MS, Mitchell KE, Alison J, van Gestel AJ, Zogg S, Gagnon P, Abascal-Bolado B, Vagaggini B, Garcia-Aymerich J, Jenkins SC, Romme EA, Kon SS, Albert PS, Waschki B, Shrikrishna D, Singh SJ, Hopkinson NS, Miedinger D, Benzo RP, Maltais F, Paggiaro P, McKeough ZJ, Polkey MI, Hill K, Man WD, Clarenbach CF, Hernandes NA, Savi D, Wootton S, Furlanetto KC, Cindy Ng LW, Vaes AW, Jenkins C, Eastwood PR, Jarreta D, Kirsten A, Brooks D, Hillman DR, Sant'Anna T, Meijer K, Dürr S, Rutten EP, Kohler M, Probst VS, Tal-Singer R, Gil EG, den Brinker AC, Leuppi JD, Calverley PM, Smeenk FW, Costello RW, Gramm M, Goldstein R, Groenen MT, Magnussen H, Wouters EF, ZuWallack RL, Amft O, Watz H, Spruit MA.

Chron Respir Dis. 2017 Aug;14(3):256-269. doi: 10.1177/1479972316687207. Epub 2017 Feb 24.


Asymptomatic congenital tuberculosis: A case report.

Meyer Sauteur PM, Marques-Maggio E, Relly C, Keller PM, Clarenbach CF, Berger C.

Medicine (Baltimore). 2017 Jul;96(29):e7562. doi: 10.1097/MD.0000000000007562.


Accelerometer- versus questionnaire-based assessment of physical activity and their changes over time in patients with COPD.

Sievi NA, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Kohler M, Clarenbach CF.

Int J Chron Obstruct Pulmon Dis. 2017 Apr 10;12:1113-1118. doi: 10.2147/COPD.S130195. eCollection 2017.


Determinants of annual change in physical activity in COPD.

Clarenbach CF, Sievi NA, Haile SR, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Kohler M.

Respirology. 2017 Aug;22(6):1133-1139. doi: 10.1111/resp.13035. Epub 2017 Mar 30.


Idiopathic Pulmonary Fibrosis in Switzerland: Diagnosis and Treatment.

Funke-Chambour M, Azzola A, Adler D, Barazzone-Argiroffo C, Benden C, Boehler A, Bridevaux PO, Brutsche M, Clarenbach CF, Hostettler K, Kleiner-Finger R, Nicod LP, Soccal PM, Tamm M, Geiser T, Lazor R.

Respiration. 2017;93(5):363-378. doi: 10.1159/000464332. Epub 2017 Mar 25.


Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity.

Spina G, Spruit MA, Alison J, Benzo RP, Calverley PMA, Clarenbach CF, Costello RW, Donaire-Gonzalez D, Dürr S, Garcia-Aymerich J, van Gestel AJR, Gramm M, Hernandes NA, Hill K, Hopkinson NS, Jarreta D, Kohler M, Kirsten AM, Leuppi JD, Magnussen H, Maltais F, Man WD, McKeough ZJ, Mesquita R, Miedinger D, Pitta F, Singh SJ, Smeenk FWJM, Tal-Singer R, Vagaggini B, Waschki B, Watz H, Wouters EFM, Zogg S, den Brinker AC.

Thorax. 2017 Aug;72(8):694-701. doi: 10.1136/thoraxjnl-2016-208900. Epub 2017 Jan 12.


Real-world asthma management with inhaler devices in Switzerland-results of the asthma survey.

Clarenbach CF, Nicod LP, Kohler M.

J Thorac Dis. 2016 Nov;8(11):3096-3104. doi: 10.21037/jtd.2016.11.95.


Target-controlled versus fractionated propofol sedation in flexible bronchoscopy: A randomized noninferiority trial.

Franzen D, Bratton DJ, Clarenbach CF, Freitag L, Kohler M.

Respirology. 2016 Nov;21(8):1445-1451. doi: 10.1111/resp.12830. Epub 2016 Jun 15.


Chronic Obstructive Pulmonary Disease and Cardiac Repolarization: Data from a Randomized Controlled Trial.

Sievi NA, Clarenbach CF, Kohler M.

Respiration. 2016;91(4):288-95. doi: 10.1159/000445030. Epub 2016 Apr 15.


Effect of rituximab on pulmonary function in patients with rheumatoid arthritis.

Franzen D, Ciurea A, Bratton DJ, Clarenbach CF, Latshang TD, Russi EW, Kyburz D, Kohler M.

Pulm Pharmacol Ther. 2016 Apr;37:24-9. doi: 10.1016/j.pupt.2016.02.002. Epub 2016 Feb 8.


Prevalence and Risk Factors of Sleep Disordered Breathing in Fabry disease: A Prospective Cohort Study.

Franzen D, Gerard N, Bratton DJ, Wons A, Gaisl T, Sievi NA, Clarenbach CF, Kohler M, Krayenbühl PA.

Medicine (Baltimore). 2015 Dec;94(52):e2413. doi: 10.1097/MD.0000000000002413.


Physical inactivity and arterial stiffness in COPD.

Sievi NA, Franzen D, Kohler M, Clarenbach CF.

Int J Chron Obstruct Pulmon Dis. 2015 Sep 10;10:1891-7. doi: 10.2147/COPD.S90943. eCollection 2015.


Lung Volume Reduction Surgery and Improvement of Endothelial Function and Blood Pressure in Patients with Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial.

Clarenbach CF, Sievi NA, Brock M, Schneiter D, Weder W, Kohler M.

Am J Respir Crit Care Med. 2015 Aug 1;192(3):307-14. doi: 10.1164/rccm.201503-0453OC.


Coronary artery calcification, epicardial fat burden, and cardiovascular events in chronic obstructive pulmonary disease.

Gaisl T, Schlatzer C, Schwarz EI, Possner M, Stehli J, Sievi NA, Clarenbach CF, Dey D, Slomka PJ, Kaufmann PA, Kohler M.

PLoS One. 2015 May 26;10(5):e0126613. doi: 10.1371/journal.pone.0126613. eCollection 2015.


Intrathoracic pressure swings induced by simulated obstructive sleep apnoea promote arrhythmias in paroxysmal atrial fibrillation.

Schlatzer C, Schwarz EI, Sievi NA, Clarenbach CF, Gaisl T, Haegeli LM, Duru F, Stradling JR, Kohler M.

Europace. 2016 Jan;18(1):64-70. doi: 10.1093/europace/euv122. Epub 2015 May 19.


Impact of comorbidities on physical activity in COPD.

Sievi NA, Senn O, Brack T, Brutsche MH, Frey M, Irani S, Leuppi JD, Thurnheer R, Franzen D, Kohler M, Clarenbach CF.

Respirology. 2015 Apr;20(3):413-8. doi: 10.1111/resp.12456. Epub 2015 Jan 6.


Accuracy of the Hospital Anxiety and Depression Scale for identifying depression in chronic obstructive pulmonary disease patients.

Nowak C, Sievi NA, Clarenbach CF, Schwarz EI, Schlatzer C, Brack T, Brutsche M, Frey M, Irani S, Leuppi JD, Rüdiger J, Thurnheer R, Kohler M.

Pulm Med. 2014;2014:973858. doi: 10.1155/2014/973858. Epub 2014 Dec 4.


Physical activity and the frequency of acute exacerbations in patients with chronic obstructive pulmonary disease.

Schönmann M, Sievi NA, Clarenbach CF, Brack T, Brutsche M, Frey M, Irani S, Leuppi JD, Ruediger J, Senn O, Thurnheer R, Kohler M.

Lung. 2015 Feb;193(1):63-70. doi: 10.1007/s00408-014-9673-7. Epub 2014 Dec 13.


Predictors of the overlap syndrome and its association with comorbidities in patients with chronic obstructive pulmonary disease.

Steveling EH, Clarenbach CF, Miedinger D, Enz C, Dürr S, Maier S, Sievi N, Zogg S, Leuppi JD, Kohler M.

Respiration. 2014;88(6):451-7. doi: 10.1159/000368615. Epub 2014 Nov 28.


Association between peripheral muscle strength, exercise performance, and physical activity in daily life in patients with Chronic Obstructive Pulmonary Disease.

Rausch-Osthoff AK, Kohler M, Sievi NA, Clarenbach CF, van Gestel AJ.

Multidiscip Respir Med. 2014 Jul 3;9(1):37. doi: 10.1186/2049-6958-9-37. eCollection 2014.


[Differences and similarities in the evaluation and diagnostic workup].

Clarenbach CF, Kohler M.

Ther Umsch. 2014 May;71(5):262-6. doi: 10.1024/0040-5930/a000511. Review. German.


High prevalence of altered cardiac repolarization in patients with COPD.

Sievi NA, Clarenbach CF, Camen G, Rossi VA, van Gestel AJ, Kohler M.

BMC Pulm Med. 2014 Apr 2;14:55. doi: 10.1186/1471-2466-14-55.


The speed of blood pressure fluctuations in patients with chronic obstructive pulmonary disease.

van Gestel AJ, Clarenbach CF, Stöwhas AC, Rossi VA, Sievi NA, Camen G, Kohler M.

Heart Lung Circ. 2014 Mar;23(3):280-6. doi: 10.1016/j.hlc.2013.08.010. Epub 2013 Sep 1.


Quantifying the speed of fluctuations in systolic blood pressure.

van Gestel AJ, Camen G, Clarenbach CF, Sievi N, Rossi VA, Kohler M.

Hypertens Res. 2013 Dec;36(12):1039-44. doi: 10.1038/hr.2013.62. Epub 2013 Jun 20.


Effect of simulated obstructive hypopnea and apnea on thoracic aortic wall transmural pressures.

Clarenbach CF, Camen G, Sievi NA, Wyss C, Stradling JR, Kohler M.

J Appl Physiol (1985). 2013 Sep 1;115(5):613-7. doi: 10.1152/japplphysiol.00439.2013. Epub 2013 Jun 13.


The effects of Provent on moderate to severe obstructive sleep apnoea during continuous positive airway pressure therapy withdrawal: a randomised controlled trial.

Rossi VA, Winter B, Rahman NM, Yu LM, Fallon J, Clarenbach CF, Bloch KE, Stradling JR, Kohler M.

Thorax. 2013 Sep;68(9):854-9. doi: 10.1136/thoraxjnl-2013-203508. Epub 2013 May 30.


Determinants of endothelial function in patients with COPD.

Clarenbach CF, Senn O, Sievi NA, Camen G, van Gestel AJ, Rossi VA, Puhan MA, Thurnheer R, Russi EW, Kohler M.

Eur Respir J. 2013 Nov;42(5):1194-204. doi: 10.1183/09031936.00144612. Epub 2013 Feb 21.


Sympathetic overactivity and cardiovascular disease in patients with chronic obstructive pulmonary disease (COPD).

van Gestel AJ, Kohler M, Clarenbach CF.

Discov Med. 2012 Dec;14(79):359-68. Review.


Predicting daily physical activity in patients with chronic obstructive pulmonary disease.

van Gestel AJ, Clarenbach CF, Stöwhas AC, Rossi VA, Sievi NA, Camen G, Russi EW, Kohler M.

PLoS One. 2012;7(11):e48081. doi: 10.1371/journal.pone.0048081. Epub 2012 Nov 2.


Lung function and breathing pattern in subjects developing high altitude pulmonary edema.

Clarenbach CF, Senn O, Christ AL, Fischler M, Maggiorini M, Bloch KE.

PLoS One. 2012;7(7):e41188. doi: 10.1371/journal.pone.0041188. Epub 2012 Jul 19.


The effects of simulated obstructive apnea and hypopnea on arrhythmic potential in healthy subjects.

Camen G, Clarenbach CF, Stöwhas AC, Rossi VA, Sievi NA, Stradling JR, Kohler M.

Eur J Appl Physiol. 2013 Feb;113(2):489-96. doi: 10.1007/s00421-012-2457-y. Epub 2012 Jul 18.


Vascular dysfunction in chronic obstructive pulmonary disease: current evidence and perspectives.

Clarenbach CF, Thurnheer R, Kohler M.

Expert Rev Respir Med. 2012 Feb;6(1):37-43. doi: 10.1586/ers.11.82. Review.


Prevalence and prediction of exercise-induced oxygen desaturation in patients with chronic obstructive pulmonary disease.

van Gestel AJ, Clarenbach CF, Stöwhas AC, Teschler S, Russi EW, Teschler H, Kohler M.

Respiration. 2012;84(5):353-9. doi: 10.1159/000332833. Epub 2012 Jan 20.


Comparison of photoplethysmographic and arterial tonometry-derived indices of arterial stiffness.

Clarenbach CF, Stoewhas AC, van Gestel AJ, Latshang TD, Lo Cascio CM, Bloch KE, Kohler M.

Hypertens Res. 2012 Feb;35(2):228-33. doi: 10.1038/hr.2011.168. Epub 2011 Oct 13.


Is obstructive sleep apnea a risk factor for diabetes?

Clarenbach CF, West SD, Kohler M.

Discov Med. 2011 Jul;12(62):17-24. Review.


[Is COPD a Cardiovascular Risk Factor?].

Clarenbach CF, Kohler M.

Praxis (Bern 1994). 2011 Jan 19;100(2):85-90. German.


Disability and survival in Duchenne muscular dystrophy.

Kohler M, Clarenbach CF, Bahler C, Brack T, Russi EW, Bloch KE.

J Neurol Neurosurg Psychiatry. 2009 Mar;80(3):320-5. doi: 10.1136/jnnp.2007.141721. Epub 2008 Aug 19.


Does nasal decongestion improve obstructive sleep apnea?

Clarenbach CF, Kohler M, Senn O, Thurnheer R, Bloch KE.

J Sleep Res. 2008 Dec;17(4):444-9. doi: 10.1111/j.1365-2869.2008.00667.x. Epub 2008 Aug 15.


Periodic whole body acceleration: a novel therapy for cardiovascular disease.

Kohler M, Amann-Vesti BR, Clarenbach CF, Brack T, Noll G, Russi EW, Bloch KE.

Vasa. 2007 Nov;36(4):261-6.


Daytime Cheyne-Stokes respiration in ambulatory patients with severe congestive heart failure is associated with increased mortality.

Brack T, Thüer I, Clarenbach CF, Senn O, Noll G, Russi EW, Bloch KE.

Chest. 2007 Nov;132(5):1463-71. Epub 2007 Jul 23.


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