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Items: 1 to 50 of 106

1.

Mitonuclear gene X environment effects on lifespan and health: How common, how big?

Drummond E, Short E, Clancy D.

Mitochondrion. 2019 Jun 26;49:12-18. doi: 10.1016/j.mito.2019.06.009. [Epub ahead of print]

PMID:
31254634
2.

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.

Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M.

Cell Death Differ. 2019 Mar;26(3):395-408. doi: 10.1038/s41418-018-0261-x. Epub 2019 Jan 8. Review.

PMID:
30622307
3.

Methylation of FKBP5 and SLC6A4 in Relation to Treatment Response to Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder.

Bishop JR, Lee AM, Mills LJ, Thuras PD, Eum S, Clancy D, Erbes CR, Polusny MA, Lamberty GJ, Lim KO.

Front Psychiatry. 2018 Sep 18;9:418. doi: 10.3389/fpsyt.2018.00418. eCollection 2018.

4.

Precise Estimates of Persistence Time for SIS Infections in Heterogeneous Populations.

Clancy D.

Bull Math Biol. 2018 Nov;80(11):2871-2896. doi: 10.1007/s11538-018-0491-6. Epub 2018 Sep 11.

PMID:
30206808
5.

iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.

Oikonomidi I, Burbridge E, Cavadas M, Sullivan G, Collis B, Naegele H, Clancy D, Brezinova J, Hu T, Bileck A, Gerner C, Bolado A, von Kriegsheim A, Martin SJ, Steinberg F, Strisovsky K, Adrain C.

Elife. 2018 Jun 13;7. pii: e35032. doi: 10.7554/eLife.35032.

6.

Identification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activation.

Sullivan GP, Davidovich PB, Sura-Trueba S, Belotcerkovskaya E, Henry CM, Clancy DM, Zinoveva A, Mametnabiev T, Garabadzhiu AV, Martin SJ.

FEBS Open Bio. 2018 Mar 25;8(5):751-763. doi: 10.1002/2211-5463.12406. eCollection 2018 May.

7.

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential.

Feltham R, Jamal K, Tenev T, Liccardi G, Jaco I, Domingues CM, Morris O, John SW, Annibaldi A, Widya M, Kearney CJ, Clancy D, Elliott PR, Glatter T, Qiao Q, Thompson AJ, Nesvizhskii A, Schmidt A, Komander D, Wu H, Martin S, Meier P.

Cell Rep. 2018 Apr 10;23(2):470-484. doi: 10.1016/j.celrep.2018.03.054.

8.

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing.

Clancy DM, Sullivan GP, Moran HBT, Henry CM, Reeves EP, McElvaney NG, Lavelle EC, Martin SJ.

Cell Rep. 2018 Mar 13;22(11):2937-2950. doi: 10.1016/j.celrep.2018.02.062.

9.

Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases.

Sullivan GP, Henry CM, Clancy DM, Mametnabiev T, Belotcerkovskaya E, Davidovich P, Sura-Trueba S, Garabadzhiu AV, Martin SJ.

Cell Death Dis. 2018 Mar 7;9(3):378. doi: 10.1038/s41419-018-0385-4.

10.

Persistence time of SIS infections in heterogeneous populations and networks.

Clancy D.

J Math Biol. 2018 Sep;77(3):545-570. doi: 10.1007/s00285-018-1222-1. Epub 2018 Feb 23.

11.

Application of updated guidelines on diastolic dysfunction in patients with severe sepsis and septic shock.

Clancy DJ, Scully T, Slama M, Huang S, McLean AS, Orde SR.

Ann Intensive Care. 2017 Dec 19;7(1):121. doi: 10.1186/s13613-017-0342-x.

12.

2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion.

Chiew AL, Page CB, Clancy D, Mostafa A, Roberts MS, Isbister GK.

Clin Toxicol (Phila). 2018 May;56(5):377-380. doi: 10.1080/15563650.2017.1385790. Epub 2017 Oct 9.

PMID:
28988498
13.

Tension pneumomediastinum: A literal form of chest tightness.

Clancy DJ, Lane AS, Flynn PW, Seppelt IM.

J Intensive Care Soc. 2017 Feb;18(1):52-56. doi: 10.1177/1751143716662665. Epub 2016 Aug 3.

14.

Detecting impaired myocardial relaxation in sepsis with a novel tissue Doppler parameter (septal e'/s').

Clancy DJ, Slama M, Huang S, Scully T, McLean AS, Orde SR.

Crit Care. 2017 Jul 14;21(1):175. doi: 10.1186/s13054-017-1727-9.

15.

Among-site variability in the stochastic dynamics of East African coral reefs.

Allen KA, Bruno JF, Chong F, Clancy D, McClanahan TR, Spencer M, Żychaluk K.

PeerJ. 2017 May 17;5:e3290. doi: 10.7717/peerj.3290. eCollection 2017.

16.

Synthetic cannabinoid use in an acute psychiatric inpatient unit.

Clancy RV, Hodgson RC, Kendurkar A, Terry MA, Dadd L, Clancy DM, Ryan K, Hatzistylis M, Tinman BG.

Int J Ment Health Nurs. 2018 Apr;27(2):600-607. doi: 10.1111/inm.12341. Epub 2017 May 15.

PMID:
28503792
17.

Neutrophil extracellular traps can serve as platforms for processing and activation of IL-1 family cytokines.

Clancy DM, Henry CM, Sullivan GP, Martin SJ.

FEBS J. 2017 Jun;284(11):1712-1725. doi: 10.1111/febs.14075. Epub 2017 Apr 26.

18.

Reversal in order of ventricular filling is associated with a positive fluid balance in sepsis.

Scully T, Clancy D, McLean AS, Orde S.

Intensive Care Med. 2017 Jun;43(6):940-941. doi: 10.1007/s00134-017-4769-1. Epub 2017 Mar 23. No abstract available.

PMID:
28337507
19.

Getting a gRIP on Flu by Casting the DAI.

Clancy DM, Martin SJ.

Cell Host Microbe. 2016 Nov 9;20(5):552-554. doi: 10.1016/j.chom.2016.10.013.

20.

Kinetic Model Development for Accelerated Stability Studies.

Clancy D, Hodnett N, Orr R, Owen M, Peterson J.

AAPS PharmSciTech. 2017 May;18(4):1158-1176. doi: 10.1208/s12249-016-0565-4. Epub 2016 Jul 15.

PMID:
27422651
21.

Production of biologically active IL-36 family cytokines through insertion of N-terminal caspase cleavage motifs.

Clancy DM, Henry CM, Davidovich PB, Sullivan GP, Belotcerkovskaya E, Martin SJ.

FEBS Open Bio. 2016 Mar 12;6(4):338-48. doi: 10.1002/2211-5463.12044. eCollection 2016 Apr.

22.

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines.

Henry CM, Sullivan GP, Clancy DM, Afonina IS, Kulms D, Martin SJ.

Cell Rep. 2016 Feb 2;14(4):708-722. doi: 10.1016/j.celrep.2015.12.072. Epub 2016 Jan 14.

23.

Complete mitochondrial genome sequences of thirteen globally sourced strains of fruit fly (Drosophila melanogaster) form a powerful model for mitochondrial research.

Wolff JN, Camus MF, Clancy DJ, Dowling DK.

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Nov;27(6):4672-4674. Epub 2015 Dec 28.

PMID:
26709744
24.

Generality of endemic prevalence formulae.

Clancy D.

Math Biosci. 2015 Nov;269:30-6. doi: 10.1016/j.mbs.2015.08.011. Epub 2015 Aug 29.

PMID:
26321688
25.

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis.

Cullen SP, Kearney CJ, Clancy DM, Martin SJ.

Cell Rep. 2015 Jun 16;11(10):1535-48. doi: 10.1016/j.celrep.2015.05.003. Epub 2015 May 28.

26.

Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.

Kearney CJ, Cullen SP, Tynan GA, Henry CM, Clancy D, Lavelle EC, Martin SJ.

Cell Death Differ. 2015 Aug;22(8):1313-27. doi: 10.1038/cdd.2014.222. Epub 2015 Jan 23.

27.

RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.

Kearney CJ, Cullen SP, Clancy D, Martin SJ.

FEBS J. 2014 Nov;281(21):4921-34. doi: 10.1111/febs.13034. Epub 2014 Oct 4.

28.

Replace Obamacare mandates with consumer choice.

Clancy D.

Mod Healthc. 2013 Nov 25;43(47):23. No abstract available.

PMID:
24416871
29.

Effectiveness of simulated interventions in reducing the estimated prevalence of Salmonella in UK pig herds.

Berriman AD, Clancy D, Clough HE, Armstrong D, Christley RM.

PLoS One. 2013 Jun 28;8(6):e66054. doi: 10.1371/journal.pone.0066054. Print 2013.

30.

Semi-stochastic models for Salmonella infection within finishing pig units in the UK.

Berriman AD, Clancy D, Clough HE, Christley RM.

Math Biosci. 2013 Oct;245(2):148-56. doi: 10.1016/j.mbs.2013.06.004. Epub 2013 Jun 21.

31.
32.

The effect of population heterogeneities upon spread of infection.

Clancy D, Pearce CJ.

J Math Biol. 2013 Oct;67(4):963-87. doi: 10.1007/s00285-012-0578-x. Epub 2012 Sep 2.

PMID:
22941453
33.

Reliability and variability of sleep and activity as biomarkers of ageing in Drosophila.

Koudounas S, Green EW, Clancy D.

Biogerontology. 2012 Oct;13(5):489-99. doi: 10.1007/s10522-012-9393-4. Epub 2012 Aug 24.

PMID:
22918750
34.

Mitochondria, maternal inheritance, and male aging.

Camus MF, Clancy DJ, Dowling DK.

Curr Biol. 2012 Sep 25;22(18):1717-21. doi: 10.1016/j.cub.2012.07.018. Epub 2012 Aug 2.

35.

ECG of the month. ECG in a man with metastatic malignancy. Sinus tachycardia at 110 beats/minute.

Clancy DL, Husain S, Hanna EB.

J La State Med Soc. 2012 Mar-Apr;164(2):97-8. No abstract available.

PMID:
22685862
36.

Flies, worms and the Free Radical Theory of ageing.

Clancy D, Birdsall J.

Ageing Res Rev. 2013 Jan;12(1):404-12. doi: 10.1016/j.arr.2012.03.011. Epub 2012 Apr 5. Review.

PMID:
22504404
37.

Data-driven models for regional coral-reef dynamics.

Żychaluk K, Bruno JF, Clancy D, McClanahan TR, Spencer M.

Ecol Lett. 2012 Feb;15(2):151-8. doi: 10.1111/j.1461-0248.2011.01720.x. Epub 2011 Dec 21.

PMID:
22188529
38.

Mitochondrial DNA variants in Drosophila melanogaster are expressed at the level of the organismal phenotype.

Aw WC, Correa CC, Clancy DJ, Ballard JW.

Mitochondrion. 2011 Sep;11(5):756-63. doi: 10.1016/j.mito.2011.06.012. Epub 2011 Jul 5.

PMID:
21757031
39.

The enriched opportunities programme for people with dementia: a cluster-randomised controlled trial in 10 extra care housing schemes.

Brooker DJ, Argyle E, Scally AJ, Clancy D.

Aging Ment Health. 2011 Nov;15(8):1008-17. doi: 10.1080/13607863.2011.583628. Epub 2011 Jun 27.

PMID:
21702705
40.

Cytoplasmic male sterility in Drosophila melanogaster associated with a mitochondrial CYTB variant.

Clancy DJ, Hime GR, Shirras AD.

Heredity (Edinb). 2011 Oct;107(4):374-6. doi: 10.1038/hdy.2011.12. Epub 2011 Mar 16. No abstract available.

41.

Quantitative analysis of culture using millions of digitized books.

Michel JB, Shen YK, Aiden AP, Veres A, Gray MK; Google Books Team, Pickett JP, Hoiberg D, Clancy D, Norvig P, Orwant J, Pinker S, Nowak MA, Aiden EL.

Science. 2011 Jan 14;331(6014):176-82. doi: 10.1126/science.1199644. Epub 2010 Dec 16.

42.

Stroke due to migration of a hemodialysis catheter across the atrial septum.

Atluri P, Falco V, Yount RD, Clancy DL.

J La State Med Soc. 2010 Jul-Aug;162(4):196-7. No abstract available.

PMID:
20882810
43.

The effect of waning immunity on long-term behaviour of stochastic models for the spread of infection.

Clancy D, Mendy ST.

J Math Biol. 2010 Oct;61(4):527-44. doi: 10.1007/s00285-009-0313-4. Epub 2009 Nov 26.

PMID:
19941137
44.

Ventricular septal defect from a gunshot to the buttock.

Jones MB, Hunt JP, Clancy DL, Dominguez MJ, Helmcke FR, Rochon BJ, Chaudhry AE.

J La State Med Soc. 2009 May-Jun;161(3):148, 150, 152. No abstract available.

PMID:
19772037
45.

Quantifying exposure to vero-cytotoxigenic Escherichia coli O157 in milk sold as pasteurized: a model-based approach.

Clough HE, Clancy D, French NP.

Int J Food Microbiol. 2009 May 31;131(2-3):95-105. doi: 10.1016/j.ijfoodmicro.2008.12.036. Epub 2009 Jan 27.

PMID:
19232769
46.

Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.

Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE.

Bioorg Med Chem Lett. 2009 Feb 15;19(4):1177-82. doi: 10.1016/j.bmcl.2008.12.085. Epub 2008 Dec 25.

PMID:
19138846
47.

Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues.

Sparks SM, Banker P, Bickett DM, Clancy DC, Dickerson SH, Garrido DM, Golden PL, Peat AJ, Sheckler LR, Tavares FX, Thomson SA, Weiel JE.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):981-5. doi: 10.1016/j.bmcl.2008.11.084. Epub 2008 Nov 27.

PMID:
19095443
48.

Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups.

Sparks SM, Banker P, Bickett DM, Carter HL, Clancy DC, Dickerson SH, Dwornik KA, Garrido DM, Golden PL, Nolte RT, Peat AJ, Sheckler LR, Tavares FX, Thomson SA, Wang L, Weiel JE.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):976-80. doi: 10.1016/j.bmcl.2008.11.085. Epub 2008 Nov 27.

PMID:
19095442
49.

DmWRNexo is a 3'-5' exonuclease: phenotypic and biochemical characterization of mutants of the Drosophila orthologue of human WRN exonuclease.

Boubriak I, Mason PA, Clancy DJ, Dockray J, Saunders RD, Cox LS.

Biogerontology. 2009 Jun;10(3):267-77. doi: 10.1007/s10522-008-9181-3. Epub 2008 Oct 28.

PMID:
18956248
50.

Variation in mitochondrial genotype has substantial lifespan effects which may be modulated by nuclear background.

Clancy DJ.

Aging Cell. 2008 Dec;7(6):795-804. doi: 10.1111/j.1474-9726.2008.00428.x. Epub 2008 Aug 21.

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