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Items: 39

1.

Inhibition of EphB4-ephrin-B2 signaling reprograms the tumor immune microenvironment in head and neck cancers.

Bhatia S, Oweida A, Lennon S, Darragh LB, Milner D, Phan AV, Mueller AC, Van Court B, Raben D, Serkova NJ, Wang XJ, Jimeno A, Clambey ET, Pasquale EB, Karam SD.

Cancer Res. 2019 Mar 20. pii: canres.3257.2018. doi: 10.1158/0008-5472.CAN-18-3257. [Epub ahead of print]

PMID:
30894369
2.

Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy.

Tu MM, Lee FYF, Jones RT, Kimball AK, Saravia E, Graziano RF, Coleman B, Menard K, Yan J, Michaud E, Chang H, Abdel-Hafiz HA, Rozhok AI, Duex JE, Agarwal N, Chauca-Diaz A, Johnson LK, Ng TL, Cambier JC, Clambey ET, Costello JC, Korman AJ, Theodorescu D.

Sci Adv. 2019 Feb 20;5(2):eaav2437. doi: 10.1126/sciadv.aav2437. eCollection 2019 Feb.

3.

Aging of Antiviral CD8+ Memory T Cells Fosters Increased Survival, Metabolic Adaptations, and Lymphoid Tissue Homing.

Davenport B, Eberlein J, van der Heide V, Jhun K, Nguyen TT, Victorino F, Trotta A, Chipuk J, Yi Z, Zhang W, Clambey ET, Scott DK, Homann D.

J Immunol. 2019 Jan 15;202(2):460-475. doi: 10.4049/jimmunol.1801277. Epub 2018 Dec 14.

PMID:
30552164
4.

CD8+ T cells modulate autosomal dominant polycystic kidney disease progression.

Kleczko EK, Marsh KH, Tyler LC, Furgeson SB, Bullock BL, Altmann CJ, Miyazaki M, Gitomer BY, Harris PC, Weiser-Evans MCM, Chonchol MB, Clambey ET, Nemenoff RA, Hopp K.

Kidney Int. 2018 Dec;94(6):1127-1140. doi: 10.1016/j.kint.2018.06.025. Epub 2018 Sep 21.

5.

Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis.

Niemeyer BF, Oko LM, Medina EM, Oldenburg DG, White DW, Cool CD, Clambey ET, van Dyk LF.

J Virol. 2018 Feb 26;92(6). pii: e01604-17. doi: 10.1128/JVI.01604-17. Print 2018 Mar 15.

6.

A Beginner's Guide to Analyzing and Visualizing Mass Cytometry Data.

Kimball AK, Oko LM, Bullock BL, Nemenoff RA, van Dyk LF, Clambey ET.

J Immunol. 2018 Jan 1;200(1):3-22. doi: 10.4049/jimmunol.1701494.

7.

Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.

Kwak JW, Laskowski J, Li HY, McSharry MV, Sippel TR, Bullock BL, Johnson AM, Poczobutt JM, Neuwelt AJ, Malkoski SP, Weiser-Evans MC, Lambris JD, Clambey ET, Thurman JM, Nemenoff RA.

Cancer Res. 2018 Jan 1;78(1):143-156. doi: 10.1158/0008-5472.CAN-17-0240. Epub 2017 Nov 8.

8.

Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.

Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaah5360. doi: 10.1126/scitranslmed.aah5360.

9.

The Tumor Microenvironment Regulates Sensitivity of Murine Lung Tumors to PD-1/PD-L1 Antibody Blockade.

Li HY, McSharry M, Bullock B, Nguyen TT, Kwak J, Poczobutt JM, Sippel TR, Heasley LE, Weiser-Evans MC, Clambey ET, Nemenoff RA.

Cancer Immunol Res. 2017 Sep;5(9):767-777. doi: 10.1158/2326-6066.CIR-16-0365. Epub 2017 Aug 17.

10.

Disruption of Transplant Tolerance by an "Incognito" Form of CD8 T Cell-Dependent Memory.

Nelsen MK, Beard KS, Plenter RJ, Kedl RM, Clambey ET, Gill RG.

Am J Transplant. 2017 Jul;17(7):1742-1753. doi: 10.1111/ajt.14194. Epub 2017 Feb 21.

11.

Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalities.

Eberlein J, Davenport B, Nguyen T, Victorino F, Haist K, Jhun K, Karimpour-Fard A, Hunter L, Kedl R, Clambey ET, Homann D.

J Clin Invest. 2016 Oct 3;126(10):3942-3960. doi: 10.1172/JCI88546. Epub 2016 Sep 12.

12.

Antibiotic Bactericidal Activity Is Countered by Maintaining pH Homeostasis in Mycobacterium smegmatis.

Bartek IL, Reichlen MJ, Honaker RW, Leistikow RL, Clambey ET, Scobey MS, Hinds AB, Born SE, Covey CR, Schurr MJ, Lenaerts AJ, Voskuil MI.

mSphere. 2016 Aug 24;1(4). pii: e00176-16. doi: 10.1128/mSphere.00176-16. eCollection 2016 Jul-Aug.

13.

Suppression of Antitumor Immune Responses by Human Papillomavirus through Epigenetic Downregulation of CXCL14.

Cicchini L, Westrich JA, Xu T, Vermeer DW, Berger JN, Clambey ET, Lee D, Song JI, Lambert PF, Greer RO, Lee JH, Pyeon D.

MBio. 2016 May 3;7(3). pii: e00270-16. doi: 10.1128/mBio.00270-16.

14.

Age Modifies the Association Between Obesity and Mortality in Individuals Hospitalized with Severe Sepsis.

Abbate LM, Perman SM, Clambey ET, Van Pelt RE, Ginde AA.

J Am Geriatr Soc. 2016 Apr;64(4):882-3. doi: 10.1111/jgs.14047. No abstract available. Erratum in: J Am Geriatr Soc. 2016 Jun;64(6):1383.

15.

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.

Henry CJ, Casás-Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel AE, Jimenez L, Azam T, McNamee EN, Clambey ET, Klawitter J, Serkova NJ, Tan AC, Dinarello CA, DeGregori J.

J Clin Invest. 2015 Dec;125(12):4666-80. doi: 10.1172/JCI83024. Epub 2015 Nov 9.

16.

Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody.

Victorino F, Sojka DK, Brodsky KS, McNamee EN, Masterson JC, Homann D, Yokoyama WM, Eltzschig HK, Clambey ET.

J Immunol. 2015 Nov 15;195(10):4973-85. doi: 10.4049/jimmunol.1500651. Epub 2015 Oct 9.

17.

A Conserved Gammaherpesvirus Cyclin Specifically Bypasses Host p18(INK4c) To Promote Reactivation from Latency.

Williams LM, Niemeyer BF, Franklin DS, Clambey ET, van Dyk LF.

J Virol. 2015 Nov;89(21):10821-31. doi: 10.1128/JVI.00891-15. Epub 2015 Aug 19.

18.

Gammaherpesvirus small noncoding RNAs are bifunctional elements that regulate infection and contribute to virulence in vivo.

Diebel KW, Oko LM, Medina EM, Niemeyer BF, Warren CJ, Claypool DJ, Tibbetts SA, Cool CD, Clambey ET, van Dyk LF.

MBio. 2015 Feb 17;6(1):e01670-14. doi: 10.1128/mBio.01670-14.

19.

Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction.

Desch AN, Gibbings SL, Clambey ET, Janssen WJ, Slansky JE, Kedl RM, Henson PM, Jakubzick C.

Nat Commun. 2014 Aug 19;5:4674. doi: 10.1038/ncomms5674.

20.

Molecules in medicine mini review: the αβ T cell receptor.

Clambey ET, Davenport B, Kappler JW, Marrack P, Homann D.

J Mol Med (Berl). 2014 Jul;92(7):735-41. doi: 10.1007/s00109-014-1145-2. Epub 2014 May 22. Review.

21.

Perioperative organ injury.

Bartels K, Karhausen J, Clambey ET, Grenz A, Eltzschig HK.

Anesthesiology. 2013 Dec;119(6):1474-89. doi: 10.1097/ALN.0000000000000022. Review.

22.

The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells.

Clambey ET, Collins B, Young MH, Eberlein J, David A, Kappler JW, Marrack P.

PLoS One. 2013;8(2):e57435. doi: 10.1371/journal.pone.0057435. Epub 2013 Feb 26.

23.

CD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury.

Ehrentraut H, Clambey ET, McNamee EN, Brodsky KS, Ehrentraut SF, Poth JM, Riegel AK, Westrich JA, Colgan SP, Eltzschig HK.

FASEB J. 2013 Jun;27(6):2207-19. doi: 10.1096/fj.12-225201. Epub 2013 Feb 14.

24.

Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line.

Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW.

Eur J Immunol. 2013 Feb;43(2):521-32. doi: 10.1002/eji.201242757. Epub 2012 Dec 27.

25.

Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release.

Grenz A, Kim JH, Bauerle JD, Tak E, Eltzschig HK, Clambey ET.

J Immunol. 2012 Nov 1;189(9):4566-73. doi: 10.4049/jimmunol.1201651. Epub 2012 Oct 1. Retraction in: J Immunol. 2017 Jul 1;199(1):363.

26.

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa.

Clambey ET, McNamee EN, Westrich JA, Glover LE, Campbell EL, Jedlicka P, de Zoeten EF, Cambier JC, Stenmark KR, Colgan SP, Eltzschig HK.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2784-93. doi: 10.1073/pnas.1202366109. Epub 2012 Sep 17.

27.

Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function.

McNamee EN, Korns Johnson D, Homann D, Clambey ET.

Immunol Res. 2013 Mar;55(1-3):58-70. doi: 10.1007/s12026-012-8349-8. Review.

28.

Adora2b adenosine receptor engagement enhances regulatory T cell abundance during endotoxin-induced pulmonary inflammation.

Ehrentraut H, Westrich JA, Eltzschig HK, Clambey ET.

PLoS One. 2012;7(2):e32416. doi: 10.1371/journal.pone.0032416. Epub 2012 Feb 28.

29.

Elevated tumor-associated antigen expression suppresses variant peptide vaccine responses.

Kemmler CB, Clambey ET, Kedl RM, Slansky JE.

J Immunol. 2011 Nov 1;187(9):4431-9. doi: 10.4049/jimmunol.1101555. Epub 2011 Sep 21.

30.

Purinergic regulation of airway inflammation.

Koeppen M, Di Virgilio F, Clambey ET, Eltzschig HK.

Subcell Biochem. 2011;55:159-93. doi: 10.1007/978-94-007-1217-1_7. Review.

PMID:
21560048
31.

Activation or suppression? T cell immunity in COPD lungs.

Clambey ET, Torres RM.

COPD. 2009 Apr;6(2):84-5. doi: 10.1080/15412550902835168. No abstract available.

PMID:
19378220
32.

CD4 memory T cells: what are they and what can they do?

MacLeod MK, Clambey ET, Kappler JW, Marrack P.

Semin Immunol. 2009 Apr;21(2):53-61. doi: 10.1016/j.smim.2009.02.006. Epub 2009 Mar 9. Review.

33.

Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties.

Clambey ET, White J, Kappler JW, Marrack P.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12997-3002. doi: 10.1073/pnas.0805465105. Epub 2008 Aug 26.

34.

Systemic CD8 T-cell memory response to a Salmonella pathogenicity island 2 effector is restricted to Salmonella enterica encountered in the gastrointestinal mucosa.

Jones-Carson J, McCollister BD, Clambey ET, Vázquez-Torres A.

Infect Immun. 2007 Jun;75(6):2708-16. Epub 2007 Apr 2.

35.

CD8 T cell clonal expansions & aging: a heterogeneous phenomenon with a common outcome.

Clambey ET, Kappler JW, Marrack P.

Exp Gerontol. 2007 May;42(5):407-11. Epub 2007 Jan 2. Review.

36.

Non-malignant clonal expansions of CD8+ memory T cells in aged individuals.

Clambey ET, van Dyk LF, Kappler JW, Marrack P.

Immunol Rev. 2005 Jun;205:170-89. Review.

PMID:
15882353
38.
39.

Crosslinked hemoglobin inhibits endothelium-dependent relaxations in isolated canine arteries.

Katusić ZS, Lee HC, Clambey ET.

Gen Pharmacol. 1996 Mar;27(2):239-44.

PMID:
8919636

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