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Items: 1 to 50 of 463

1.

OBEDIS Core Variables Project: European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions.

Alligier M, Barrès R, Blaak EE, Boirie Y, Bouwman J, Brunault P, Campbell K, Clément K, Farooqi IS, Farpour-Lambert NJ, Frühbeck G, Goossens GH, Hager J, Halford JCG, Hauner H, Jacobi D, Julia C, Langin D, Natali A, Neovius M, Oppert JM, Pagotto U, Palmeira AL, Roche H, Rydén M, Scheen AJ, Simon C, Sorensen TIA, Tappy L, Yki-Järvinen H, Ziegler O, Laville M.

Obes Facts. 2020 Jan 16:1-28. doi: 10.1159/000505342. [Epub ahead of print]

PMID:
31945762
2.

Corticosterone in the ventral hippocampus differentially alters accumbal dopamine output in drug-naïve and amphetamine-withdrawn rats.

Bray B, Clement KA, Bachmeier D, Weber MA, Forster GL.

Neuropharmacology. 2019 Dec 24;165:107924. doi: 10.1016/j.neuropharm.2019.107924. [Epub ahead of print]

PMID:
31881169
3.

[Is there any hope that the pharmaceutical management of obesity will change?]

Clément K.

Med Sci (Paris). 2019 Nov;35(11):819-820. doi: 10.1051/medsci/2019190. Epub 2019 Dec 17. French. No abstract available.

PMID:
31845867
4.

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI.

Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, Estivill X, Lindi V, Bradfield JP, Geller F, Speed D, Coin LJM, Loh M, Barton SJ, Beilin LJ, Bisgaard H, Bønnelykke K, Alili R, Hatoum IJ, Schramm K, Cartwright R, Charles MA, Salerno V, Clément K, Claringbould AAJ; BIOS Consortium, van Duijn CM, Moltchanova E, Eriksson JG, Elks C, Feenstra B, Flexeder C, Franks S, Frayling TM, Freathy RM, Elliott P, Widén E, Hakonarson H, Hattersley AT, Rodriguez A, Banterle M, Heinrich J, Heude B, Holloway JW, Hofman A, Hyppönen E, Inskip H, Kaplan LM, Hedman AK, Läärä E, Prokisch H, Grallert H, Lakka TA, Lawlor DA, Melbye M, Ahluwalia TS, Marinelli M, Millwood IY, Palmer LJ, Pennell CE, Perry JR, Ring SM, Savolainen MJ, Rivadeneira F, Standl M, Sunyer J, Tiesler CMT, Uitterlinden AG, Schierding W, O'Sullivan JM, Prokopenko I, Herzig KH, Smith GD, O'Reilly P, Felix JF, Buxton JL, Blakemore AIF, Ong KK, Jaddoe VWV, Grant SFA, Sebert S, McCarthy MI, Järvelin MR; Early Growth Genetics (EGG) Consortium.

Sci Adv. 2019 Sep 4;5(9):eaaw3095. doi: 10.1126/sciadv.aaw3095. eCollection 2019 Sep.

5.

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.

Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G.

Cell Metab. 2019 Dec 3;30(6):1171. doi: 10.1016/j.cmet.2019.10.011. No abstract available.

PMID:
31801056
6.

Robot-assisted Laparoscopic Nephroureterectomy for a Nephrogenic Adenoma of Ureter.

Clement KD, Thompson C, Aboumarzouk OM.

J Coll Physicians Surg Pak. 2019 Dec;29(12):S151-S153. doi: 10.29271/jcpsp.2019.12.S151.

PMID:
31779773
7.

The intestinal microbiota regulates host cholesterol homeostasis.

Le Roy T, Lécuyer E, Chassaing B, Rhimi M, Lhomme M, Boudebbouze S, Ichou F, Haro Barceló J, Huby T, Guerin M, Giral P, Maguin E, Kapel N, Gérard P, Clément K, Lesnik P.

BMC Biol. 2019 Nov 27;17(1):94. doi: 10.1186/s12915-019-0715-8.

8.

What is the Operative Cost of Managing Acute Appendicitis in the NHS: The Impact of Stump Technique and Perioperative Imaging.

Clement KD, Emslie K, Maniam P, Wilson MSJ.

World J Surg. 2019 Nov 26. doi: 10.1007/s00268-019-05306-2. [Epub ahead of print]

PMID:
31773223
9.

Assessment of computational methods for the analysis of single-cell ATAC-seq data.

Chen H, Lareau C, Andreani T, Vinyard ME, Garcia SP, Clement K, Andrade-Navarro MA, Buenrostro JD, Pinello L.

Genome Biol. 2019 Nov 18;20(1):241. doi: 10.1186/s13059-019-1854-5.

10.

Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health.

Olsson LM, Poitou C, Tremaroli V, Coupaye M, Aron-Wisnewsky J, Bäckhed F, Clément K, Caesar R.

Gut. 2019 Oct 14. pii: gutjnl-2019-319322. doi: 10.1136/gutjnl-2019-319322. [Epub ahead of print]

11.

Elevated serum ceramides are linked with obesity-associated gut dysbiosis and impaired glucose metabolism.

Kayser BD, Prifti E, Lhomme M, Belda E, Dao MC, Aron-Wisnewsky J; MICRO-Obes Consortium, Kontush A, Zucker JD, Rizkalla SW, Dugail I, Clément K.

Metabolomics. 2019 Oct 11;15(11):140. doi: 10.1007/s11306-019-1596-0.

PMID:
31605240
12.

A place for vitamin supplementation and functional food in bariatric surgery?

Aron-Wisnewsky J, Clément K.

Curr Opin Clin Nutr Metab Care. 2019 Nov;22(6):442-448. doi: 10.1097/MCO.0000000000000602.

PMID:
31589176
13.

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.

Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, Gerli MFM, Gu H, Gygi SP, Sadreyev RI, Meissner A, Yeo GW, Hochedlinger K.

Cell Stem Cell. 2019 Nov 7;25(5):622-638.e13. doi: 10.1016/j.stem.2019.08.018. Epub 2019 Oct 3.

PMID:
31588046
14.

Deciphering the cellular interplays underlying obesity-induced adipose tissue fibrosis.

Marcelin G, Silveira ALM, Martins LB, Ferreira AV, Clément K.

J Clin Invest. 2019 Oct 1;129(10):4032-4040. doi: 10.1172/JCI129192. Review.

15.

Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity.

Bravo-San Pedro JM, Sica V, Martins I, Pol J, Loos F, Maiuri MC, Durand S, Bossut N, Aprahamian F, Anagnostopoulos G, Niso-Santano M, Aranda F, Ramírez-Pardo I, Lallement J, Denom J, Boedec E, Gorwood P, Ramoz N, Clément K, Pelloux V, Rohia A, Pattou F, Raverdy V, Caiazzo R, Denis RGP, Boya P, Galluzzi L, Madeo F, Migrenne-Li S, Cruciani-Guglielmacci C, Tavernarakis N, López-Otín C, Magnan C, Kroemer G.

Cell Metab. 2019 Oct 1;30(4):754-767.e9. doi: 10.1016/j.cmet.2019.07.010. Epub 2019 Aug 15. Erratum in: Cell Metab. 2019 Dec 3;30(6):1171.

PMID:
31422903
16.

Meta-analysis of the use of sterilized mosquito net mesh for inguinal hernia repair in less economically developed countries.

Ahmad MH, Pathak S, Clement KD, Aly EH.

BJS Open. 2019 Feb 27;3(4):429-435. doi: 10.1002/bjs5.50147. eCollection 2019 Aug. Review.

17.

Increased Glucose Variability Is Associated With Major Adverse Events After Coronary Artery Bypass.

Clement KC, Suarez-Pierre A, Sebestyen K, Alejo D, DiNatale J, Whitman GJR, Matthew TL, Lawton JS.

Ann Thorac Surg. 2019 Nov;108(5):1307-1313. doi: 10.1016/j.athoracsur.2019.06.046. Epub 2019 Aug 7.

PMID:
31400320
18.

Danger in the vapor? ECMO for adolescents with status asthmaticus after vaping.

Bradford LE, Rebuli ME, Ring BJ, Jaspers I, Clement KC, Loughlin CE.

J Asthma. 2019 Jul 27:1-5. doi: 10.1080/02770903.2019.1643361. [Epub ahead of print]

PMID:
31352844
19.

Improvement of non-invasive markers of NAFLD from an individualised, web-based exercise program.

Huber Y, Pfirrmann D, Gebhardt I, Labenz C, Gehrke N, Straub BK, Ruckes C, Bantel H, Belda E, Clément K, Leeming DJ, Karsdal MA, Galle PR, Simon P, Schattenberg JM.

Aliment Pharmacol Ther. 2019 Oct;50(8):930-939. doi: 10.1111/apt.15427. Epub 2019 Jul 25.

PMID:
31342533
20.

Akkermansia muciniphila abundance is lower in severe obesity, but its increased level after bariatric surgery is not associated with metabolic health improvement.

Dao MC, Belda E, Prifti E, Everard A, Kayser BD, Bouillot JL, Chevallier JM, Pons N, Le Chatelier E, Ehrlich SD, Doré J, Aron-Wisnewsky J, Zucker JD, Cani PD, Clément K.

Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3):E446-E459. doi: 10.1152/ajpendo.00140.2019. Epub 2019 Jul 2.

PMID:
31265324
21.

Fecal Microbiota Transplantation: a Future Therapeutic Option for Obesity/Diabetes?

Aron-Wisnewsky J, Clément K, Nieuwdorp M.

Curr Diab Rep. 2019 Jun 27;19(8):51. doi: 10.1007/s11892-019-1180-z. Review.

PMID:
31250122
22.

Gut Microbiota Dysbiosis in Human Obesity: Impact of Bariatric Surgery.

Debédat J, Clément K, Aron-Wisnewsky J.

Curr Obes Rep. 2019 Sep;8(3):229-242. doi: 10.1007/s13679-019-00351-3. Review.

23.

Magnetic Resonance Imaging-targeted Biopsy Versus Systematic Biopsy in the Detection of Prostate Cancer: A Systematic Review and Meta-analysis.

Kasivisvanathan V, Stabile A, Neves JB, Giganti F, Valerio M, Shanmugabavan Y, Clement KD, Sarkar D, Philippou Y, Thurtle D, Deeks J, Emberton M, Takwoingi Y, Moore CM.

Eur Urol. 2019 Sep;76(3):284-303. doi: 10.1016/j.eururo.2019.04.043. Epub 2019 May 24. Review.

PMID:
31130434
24.

Increased glucose variability is associated with atrial fibrillation after coronary artery bypass.

Clement KC, Alejo D, DiNatale J, Whitman GJR, Matthew TL, Clement SC, Lawton JS.

J Card Surg. 2019 Jul;34(7):549-554. doi: 10.1111/jocs.14071. Epub 2019 May 17.

PMID:
31099438
25.

Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.

Gaiti F, Chaligne R, Gu H, Brand RM, Kothen-Hill S, Schulman RC, Grigorev K, Risso D, Kim KT, Pastore A, Huang KY, Alonso A, Sheridan C, Omans ND, Biederstedt E, Clement K, Wang L, Felsenfeld JA, Bhavsar EB, Aryee MJ, Allan JN, Furman R, Gnirke A, Wu CJ, Meissner A, Landau DA.

Nature. 2019 May;569(7757):576-580. doi: 10.1038/s41586-019-1198-z. Epub 2019 May 15.

26.

Impact of bariatric surgery on type 2 diabetes: contribution of inflammation and gut microbiome?

Debédat J, Amouyal C, Aron-Wisnewsky J, Clément K.

Semin Immunopathol. 2019 Jul;41(4):461-475. doi: 10.1007/s00281-019-00738-3. Epub 2019 Apr 25. Review.

27.

Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials.

Koutnikova H, Genser B, Monteiro-Sepulveda M, Faurie JM, Rizkalla S, Schrezenmeir J, Clément K.

BMJ Open. 2019 Mar 30;9(3):e017995. doi: 10.1136/bmjopen-2017-017995.

28.

Highly efficient therapeutic gene editing of human hematopoietic stem cells.

Wu Y, Zeng J, Roscoe BP, Liu P, Yao Q, Lazzarotto CR, Clement K, Cole MA, Luk K, Baricordi C, Shen AH, Ren C, Esrick EB, Manis JP, Dorfman DM, Williams DA, Biffi A, Brugnara C, Biasco L, Brendel C, Pinello L, Tsai SQ, Wolfe SA, Bauer DE.

Nat Med. 2019 May;25(5):776-783. doi: 10.1038/s41591-019-0401-y. Epub 2019 Mar 25.

29.

CRISPResso2 provides accurate and rapid genome editing sequence analysis.

Clement K, Rees H, Canver MC, Gehrke JM, Farouni R, Hsu JY, Cole MA, Liu DR, Joung JK, Bauer DE, Pinello L.

Nat Biotechnol. 2019 Mar;37(3):224-226. doi: 10.1038/s41587-019-0032-3. No abstract available.

30.

A Data Integration Multi-Omics Approach to Study Calorie Restriction-Induced Changes in Insulin Sensitivity.

Dao MC, Sokolovska N, Brazeilles R, Affeldt S, Pelloux V, Prifti E, Chilloux J, Verger EO, Kayser BD, Aron-Wisnewsky J, Ichou F, Pujos-Guillot E, Hoyles L, Juste C, Doré J, Dumas ME, Rizkalla SW, Holmes BA, Zucker JD, Clément K; MICRO-Obes Consortium.

Front Physiol. 2019 Feb 5;9:1958. doi: 10.3389/fphys.2018.01958. eCollection 2018.

31.

Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.

Kleinstiver BP, Sousa AA, Walton RT, Tak YE, Hsu JY, Clement K, Welch MM, Horng JE, Malagon-Lopez J, Scarfò I, Maus MV, Pinello L, Aryee MJ, Joung JK.

Nat Biotechnol. 2019 Mar;37(3):276-282. doi: 10.1038/s41587-018-0011-0. Epub 2019 Feb 11.

32.

Association between genetic obesity susceptibility and mother-reported eating behaviour in children up to 5 years.

de Lauzon-Guillain B, Koudou YA, Botton J, Forhan A, Carles S, Pelloux V, Clément K, Ong KK, Charles MA, Heude B; EDEN Mother-Child Cohort Study Group.

Pediatr Obes. 2019 May;14(5):e12496. doi: 10.1111/ijpo.12496. Epub 2019 Jan 31.

33.

Comparative Evaluation of Microbiota Engraftment Following Fecal Microbiota Transfer in Mice Models: Age, Kinetic and Microbial Status Matter.

Le Roy T, Debédat J, Marquet F, Da-Cunha C, Ichou F, Guerre-Millo M, Kapel N, Aron-Wisnewsky J, Clément K.

Front Microbiol. 2019 Jan 14;9:3289. doi: 10.3389/fmicb.2018.03289. eCollection 2018.

34.

Phosphatidylglycerols are induced by gut dysbiosis and inflammation, and favorably modulate adipose tissue remodeling in obesity.

Kayser BD, Lhomme M, Prifti E, Da Cunha C, Marquet F, Chain F, Naas I, Pelloux V, Dao MC, Kontush A, Rizkalla SW, Aron-Wisnewsky J, Bermúdez-Humarán LG, Oakley F, Langella P, Clément K, Dugail I.

FASEB J. 2019 Apr;33(4):4741-4754. doi: 10.1096/fj.201801897R. Epub 2019 Jan 4.

35.

Synergistic convergence of microbiota-specific systemic IgG and secretory IgA.

Fadlallah J, Sterlin D, Fieschi C, Parizot C, Dorgham K, El Kafsi H, Autaa G, Ghillani-Dalbin P, Juste C, Lepage P, Malphettes M, Galicier L, Boutboul D, Clément K, André S, Marquet F, Tresallet C, Mathian A, Miyara M, Oksenhendler E, Amoura Z, Yssel H, Larsen M, Gorochov G.

J Allergy Clin Immunol. 2019 Apr;143(4):1575-1585.e4. doi: 10.1016/j.jaci.2018.09.036. Epub 2018 Dec 13.

37.

CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.

Hsu JY, Fulco CP, Cole MA, Canver MC, Pellin D, Sher F, Farouni R, Clement K, Guo JA, Biasco L, Orkin SH, Engreitz JM, Lander ES, Joung JK, Bauer DE, Pinello L.

Nat Methods. 2018 Dec;15(12):992-993. doi: 10.1038/s41592-018-0225-6. No abstract available.

38.

Early Laparoscopic Washout may Resolve Persistent Intra-abdominal Infection Post-appendicectomy.

Allaway MGR, Clement K, Eslick GD, Cox MR.

World J Surg. 2019 Apr;43(4):998-1006. doi: 10.1007/s00268-018-4871-8.

PMID:
30478686
39.

Targets and genomic constraints of ectopic Dnmt3b expression.

Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A.

Elife. 2018 Nov 23;7. pii: e40757. doi: 10.7554/eLife.40757.

40.

Prediction of Long-Term Diabetes Remission After RYGB, Sleeve Gastrectomy, and Adjustable Gastric Banding Using DiaRem and Advanced-DiaRem Scores.

Dicker D, Golan R, Aron-Wisnewsky J, Zucker JD, Sokolowska N, Comaneshter DS, Yahalom R, Vinker S, Clément K, Rudich A.

Obes Surg. 2019 Mar;29(3):796-804. doi: 10.1007/s11695-018-3583-3.

PMID:
30467708
41.

Resistance Training and Protein Supplementation Increase Strength After Bariatric Surgery: A Randomized Controlled Trial.

Oppert JM, Bellicha A, Roda C, Bouillot JL, Torcivia A, Clement K, Poitou C, Ciangura C.

Obesity (Silver Spring). 2018 Nov;26(11):1709-1720. doi: 10.1002/oby.22317.

42.

Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons.

Ichida JK, Staats KA, Davis-Dusenbery BN, Clement K, Galloway KE, Babos KN, Shi Y, Son EY, Kiskinis E, Atwater N, Gu H, Gnirke A, Meissner A, Eggan K.

Development. 2018 Nov 21;145(22). pii: dev168617. doi: 10.1242/dev.168617.

43.

In vivo CRISPR editing with no detectable genome-wide off-target mutations.

Akcakaya P, Bobbin ML, Guo JA, Malagon-Lopez J, Clement K, Garcia SP, Fellows MD, Porritt MJ, Firth MA, Carreras A, Baccega T, Seeliger F, Bjursell M, Tsai SQ, Nguyen NT, Nitsch R, Mayr LM, Pinello L, Bohlooly-Y M, Aryee MJ, Maresca M, Joung JK.

Nature. 2018 Sep;561(7723):416-419. doi: 10.1038/s41586-018-0500-9. Epub 2018 Sep 12.

44.

Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.

Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, Plath K, Hochedlinger K.

Nat Methods. 2018 Sep;15(9):732-740. doi: 10.1038/s41592-018-0104-1. Epub 2018 Aug 20.

45.

Long-term Relapse of Type 2 Diabetes After Roux-en-Y Gastric Bypass: Prediction and Clinical Relevance.

Debédat J, Sokolovska N, Coupaye M, Panunzi S, Chakaroun R, Genser L, de Turenne G, Bouillot JL, Poitou C, Oppert JM, Blüher M, Stumvoll M, Mingrone G, Ledoux S, Zucker JD, Clément K, Aron-Wisnewsky J.

Diabetes Care. 2018 Oct;41(10):2086-2095. doi: 10.2337/dc18-0567. Epub 2018 Aug 6.

PMID:
30082327
46.

Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming.

Schwarz BA, Cetinbas M, Clement K, Walsh RM, Cheloufi S, Gu H, Langkabel J, Kamiya A, Schorle H, Meissner A, Sadreyev RI, Hochedlinger K.

Cell Stem Cell. 2018 Aug 2;23(2):289-305.e5. doi: 10.1016/j.stem.2018.06.013. Epub 2018 Jul 12.

47.

Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes.

Genser L, Aguanno D, Soula HA, Dong L, Trystram L, Assmann K, Salem JE, Vaillant JC, Oppert JM, Laugerette F, Michalski MC, Wind P, Rousset M, Brot-Laroche E, Leturque A, Clément K, Thenet S, Poitou C.

J Pathol. 2018 Oct;246(2):217-230. doi: 10.1002/path.5134. Epub 2018 Aug 28.

PMID:
29984492
48.

Mucosal-associated invariant T (MAIT) cells are depleted and prone to apoptosis in cardiometabolic disorders.

Touch S, Assmann KE, Aron-Wisnewsky J, Marquet F, Rouault C, Fradet M, Mosbah H, Consortium M, Isnard R, Helft G, Lehuen A, Poitou C, Clément K, André S; MetaCardis Consortium.

FASEB J. 2018 Apr 27:fj201800052RR. doi: 10.1096/fj.201800052RR. [Epub ahead of print]

PMID:
29957059
49.

AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing.

Clement K, Farouni R, Bauer DE, Pinello L.

Bioinformatics. 2018 Jul 1;34(13):i202-i210. doi: 10.1093/bioinformatics/bty264.

50.

[Adipose tissue fibrosis: an aggravating factor in obesity].

Marcelin G, Clément K.

Med Sci (Paris). 2018 May;34(5):424-431. doi: 10.1051/medsci/20183405015. Epub 2018 Jun 13. Review. French.

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