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Items: 1 to 50 of 180


N-cadherin Restrains PTH Activation of Lrp6/β-catenin Signaling and Osteoanabolic Action.

Revollo L, Kading J, Jeong SY, Li J, Salazar V, Mbalaviele G, Civitelli R.

J Bone Miner Res. 2019 Nov;34(11):2163-2165. doi: 10.1002/jbmr.3845. Epub 2019 Oct 11. No abstract available.


New Guidelines for Data Reporting and Statistical Analysis: Helping Authors With Transparency and Rigor in Research.

Nguyen TV, Rivadeneira F, Civitelli R.

J Bone Miner Res. 2019 Nov;34(11):1981-1984. doi: 10.1002/jbmr.3885. Epub 2019 Oct 24. No abstract available.


Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.

Xiao J, Wang C, Yao JC, Alippe Y, Xu C, Kress D, Civitelli R, Abu-Amer Y, Kanneganti TD, Link DC, Mbalaviele G.

PLoS Biol. 2018 Nov 2;16(11):e3000047. doi: 10.1371/journal.pbio.3000047. eCollection 2018 Nov.


The Rise of Research Integrity: Everyone Will Play a Role.

Civitelli R, Duffy K.

J Bone Miner Res. 2018 Nov;33(11):1914-1915. doi: 10.1002/jbmr.3601. Epub 2018 Oct 24. No abstract available.


Focusing on the Science: JBMR Manuscript Types.

Civitelli R, Westendorf J, Hofbauer L, Rivadeneira F.

J Bone Miner Res. 2018 Sep;33(9):1556-1557. doi: 10.1002/jbmr.3545. Epub 2018 Jul 16. No abstract available.


Changing of the Guard.

Civitelli R.

J Bone Miner Res. 2018 Jan;33(1):3-4. doi: 10.1002/jbmr.3311. Epub 2017 Nov 21. No abstract available.


Heterozygous deletion of both sclerostin (Sost) and connexin43 (Gja1) genes in mice is not sufficient to impair cortical bone modeling.

Grimston SK, Fontana F, Watkins M, Civitelli R.

PLoS One. 2017 Nov 17;12(11):e0187980. doi: 10.1371/journal.pone.0187980. eCollection 2017.


Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation.

Alippe Y, Wang C, Ricci B, Xiao J, Qu C, Zou W, Novack DV, Abu-Amer Y, Civitelli R, Mbalaviele G.

Sci Rep. 2017 Jul 26;7(1):6630. doi: 10.1038/s41598-017-07014-0.


Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells.

Wang C, Xu CX, Alippe Y, Qu C, Xiao J, Schipani E, Civitelli R, Abu-Amer Y, Mbalaviele G.

Sci Rep. 2017 Jul 7;7(1):4880. doi: 10.1038/s41598-017-05033-5.


Bone Turnover with Venlafaxine Treatment in Older Adults with Depression.

Rawson KS, Dixon D, Civitelli R, Peterson TR, Mulsant BH, Reynolds CF 3rd, Lenze EJ.

J Am Geriatr Soc. 2017 Sep;65(9):2057-2063. doi: 10.1111/jgs.14936. Epub 2017 May 26.


Toward personalized calcium and vitamin D supplementation.

Civitelli R, Peterson T.

Am J Clin Nutr. 2017 Apr;105(4):777-778. doi: 10.3945/ajcn.117.154278. Epub 2017 Mar 22. No abstract available.


Bone Mineral Density and Risk of Heart Failure in Older Adults: The Cardiovascular Health Study.

Fohtung RB, Brown DL, Koh WJ, Bartz TM, Carbone LD, Civitelli R, Stein PK, Chaves PH, Kestenbaum BR, Kizer JR.

J Am Heart Assoc. 2017 Mar 13;6(3). pii: e004344. doi: 10.1161/JAHA.116.004344.


N-cadherin Regulation of Bone Growth and Homeostasis Is Osteolineage Stage-Specific.

Fontana F, Hickman-Brecks CL, Salazar VS, Revollo L, Abou-Ezzi G, Grimston SK, Jeong SY, Watkins M, Fortunato M, Alippe Y, Link DC, Mbalaviele G, Civitelli R.

J Bone Miner Res. 2017 Jun;32(6):1332-1342. doi: 10.1002/jbmr.3112. Epub 2017 Mar 29.


Relationship Between Low Bone Mineral Density and Fractures With Incident Cardiovascular Disease: A Systematic Review and Meta-Analysis.

Veronese N, Stubbs B, Crepaldi G, Solmi M, Cooper C, Harvey NC, Reginster JY, Rizzoli R, Civitelli R, Schofield P, Maggi S, Lamb SE.

J Bone Miner Res. 2017 May;32(5):1126-1135. doi: 10.1002/jbmr.3089. Epub 2017 Mar 1. Review.


Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma.

Fontana F, Ge X, Su X, Hathi D, Xiang J, Cenci S, Civitelli R, Shoghi KI, Akers WJ, D'avignon A, Weilbaecher KN, Shokeen M.

Clin Cancer Res. 2017 Jan 15;23(2):416-429. doi: 10.1158/1078-0432.CCR-15-2134. Epub 2016 Aug 2.


Skeletal Metabolism, Fracture Risk, and Fracture Outcomes in Type 1 and Type 2 Diabetes.

Sellmeyer DE, Civitelli R, Hofbauer LC, Khosla S, Lecka-Czernik B, Schwartz AV.

Diabetes. 2016 Jul;65(7):1757-66. doi: 10.2337/db16-0063. Review.


A Functional Assay to Assess Connexin 43-Mediated Cell-to-Cell Communication of Second Messengers in Cultured Bone Cells.

Stains JP, Civitelli R.

Methods Mol Biol. 2016;1437:193-201. doi: 10.1007/978-1-4939-3664-9_14.


Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation.

Wang C, Qu C, Alippe Y, Bonar SL, Civitelli R, Abu-Amer Y, Hottiger MO, Mbalaviele G.

Cell Death Dis. 2016 Mar 24;7:e2153. doi: 10.1038/cddis.2016.58.


Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).

Cooper C, Bardin T, Brandi ML, Cacoub P, Caminis J, Civitelli R, Cutolo M, Dere W, Devogelaer JP, Diez-Perez A, Einhorn TA, Emonts P, Ethgen O, Kanis JA, Kaufman JM, Kvien TK, Lems WF, McCloskey E, Miossec P, Reiter S, Ringe J, Rizzoli R, Saag K, Reginster JY.

Aging Clin Exp Res. 2016 Feb;28(1):1-16. doi: 10.1007/s40520-015-0522-1. Epub 2016 Jan 8. Review.


Connexins in the skeleton.

Stains JP, Civitelli R.

Semin Cell Dev Biol. 2016 Feb;50:31-9. doi: 10.1016/j.semcdb.2015.12.017. Epub 2015 Dec 29. Review.


p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche.

Chang KH, Sengupta A, Nayak RC, Duran A, Lee SJ, Pratt RG, Wellendorf AM, Hill SE, Watkins M, Gonzalez-Nieto D, Aronow BJ, Starczynowski DT, Civitelli R, Diaz-Meco MT, Moscat J, Cancelas JA.

Cell Rep. 2014 Dec 24;9(6):2084-97. doi: 10.1016/j.celrep.2014.11.031. Epub 2014 Dec 18.


NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.

Qu C, Bonar SL, Hickman-Brecks CL, Abu-Amer S, McGeough MD, Peña CA, Broderick L, Yang C, Grimston SK, Kading J, Abu-Amer Y, Novack DV, Hoffman HM, Civitelli R, Mbalaviele G.

FASEB J. 2015 Apr;29(4):1269-79. doi: 10.1096/fj.14-264804. Epub 2014 Dec 4.


Deletion of connexin43 in osteoblasts/osteocytes leads to impaired muscle formation in mice.

Shen H, Grimston S, Civitelli R, Thomopoulos S.

J Bone Miner Res. 2015 Apr;30(4):596-605. doi: 10.1002/jbmr.2389.


N-cadherin restrains PTH activation of Lrp6/β-catenin signaling and osteoanabolic action.

Revollo L, Kading J, Jeong SY, Li J, Salazar V, Mbalaviele G, Civitelli R.

J Bone Miner Res. 2015 Feb;30(2):274-85. doi: 10.1002/jbmr.2323. Erratum in: J Bone Miner Res. 2019 Nov;34(11):2163-2165.


Depression, antidepressants, and bone health in older adults: a systematic review.

Gebara MA, Shea ML, Lipsey KL, Teitelbaum SL, Civitelli R, Müller DJ, Reynolds CF 3rd, Mulsant BH, Lenze EJ.

J Am Geriatr Soc. 2014 Aug;62(8):1434-41. doi: 10.1111/jgs.12945. Epub 2014 Jul 15. Review.


Connexin43 modulates post-natal cortical bone modeling and mechano-responsiveness.

Grimston SK, Watkins MP, Stains JP, Civitelli R.

Bonekey Rep. 2013 Nov 13;2:446. doi: 10.1038/bonekey.2013.180.


Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin.

Salazar VS, Zarkadis N, Huang L, Watkins M, Kading J, Bonar S, Norris J, Mbalaviele G, Civitelli R.

J Cell Sci. 2013 Dec 15;126(Pt 24):5598-609. doi: 10.1242/jcs.132233. Epub 2013 Oct 7.


Genetic variation in the serotonin transporter and HTR1B receptor predicts reduced bone formation during serotonin reuptake inhibitor treatment in older adults.

Garfield LD, Müller DJ, Kennedy JL, Mulsant BH, Reynolds CF 3rd, Teitelbaum SL, Civitelli R, Dixon D, Todorov AA, Lenze EJ.

World J Biol Psychiatry. 2014 Jul;15(5):404-10. doi: 10.3109/15622975.2013.832380. Epub 2013 Sep 30.


Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype.

Salazar VS, Zarkadis N, Huang L, Norris J, Grimston SK, Mbalaviele G, Civitelli R.

J Cell Sci. 2013 Nov 1;126(Pt 21):4974-84. doi: 10.1242/jcs.131953. Epub 2013 Sep 4.


Cell-cell signaling: broadening our view of the basic multicellular unit.

Sims NA, Civitelli R.

Calcif Tissue Int. 2014 Jan;94(1):2-3. doi: 10.1007/s00223-013-9766-y. Epub 2013 Jul 27. Review. No abstract available. Erratum in: Calcif Tissue Int. 2014 Jan;94(1):4.


Molecular mechanisms of osteoblast/osteocyte regulation by connexin43.

Stains JP, Watkins MP, Grimston SK, Hebert C, Civitelli R.

Calcif Tissue Int. 2014 Jan;94(1):55-67. doi: 10.1007/s00223-013-9742-6. Epub 2013 Jun 11. Review.


Cadherin-mediated cell-cell adhesion and signaling in the skeleton.

Marie PJ, Haÿ E, Modrowski D, Revollo L, Mbalaviele G, Civitelli R.

Calcif Tissue Int. 2014 Jan;94(1):46-54. doi: 10.1007/s00223-013-9733-7. Epub 2013 May 9. Review.


Risedronate increases osteoblastic differentiation and function through connexin43.

Jeong HM, Jin YH, Choi YH, Chung JO, Cho DH, Chung MY, Civitelli R, Chung DJ, Lee KY.

Biochem Biophys Res Commun. 2013 Mar 1;432(1):152-6. doi: 10.1016/j.bbrc.2013.01.068. Epub 2013 Jan 29.


Serotonin-norepinephrine reuptake inhibitor therapy in late-life depression is associated with increased marker of bone resorption.

Shea ML, Garfield LD, Teitelbaum S, Civitelli R, Mulsant BH, Reynolds CF 3rd, Dixon D, Doré P, Lenze EJ.

Osteoporos Int. 2013 May;24(5):1741-9. doi: 10.1007/s00198-012-2170-z. Epub 2013 Jan 29.


Casting new light on the sunshine vitamin.

Ralston SH, Civitelli R, Bischoff-Ferrari H.

Calcif Tissue Int. 2013 Feb;92(2):75-6. doi: 10.1007/s00223-012-9692-4. Epub 2013 Jan 18. No abstract available.


Enhanced periosteal and endocortical responses to axial tibial compression loading in conditional connexin43 deficient mice.

Grimston SK, Watkins MP, Brodt MD, Silva MJ, Civitelli R.

PLoS One. 2012;7(9):e44222. doi: 10.1371/journal.pone.0044222. Epub 2012 Sep 10.


Bisphosphonates improve trabecular bone mass and normalize cortical thickness in ovariectomized, osteoblast connexin43 deficient mice.

Watkins MP, Norris JY, Grimston SK, Zhang X, Phipps RJ, Ebetino FH, Civitelli R.

Bone. 2012 Oct;51(4):787-94. doi: 10.1016/j.bone.2012.06.018. Epub 2012 Jun 29.


Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells.

Bromberg O, Frisch BJ, Weber JM, Porter RL, Civitelli R, Calvi LM.

Blood. 2012 Jul 12;120(2):303-13. doi: 10.1182/blood-2011-09-377853. Epub 2012 May 17.


Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.

Bonar SL, Brydges SD, Mueller JL, McGeough MD, Pena C, Chen D, Grimston SK, Hickman-Brecks CL, Ravindran S, McAlinden A, Novack DV, Kastner DL, Civitelli R, Hoffman HM, Mbalaviele G.

PLoS One. 2012;7(4):e35979. doi: 10.1371/journal.pone.0035979. Epub 2012 Apr 27.


Tibial loading increases osteogenic gene expression and cortical bone volume in mature and middle-aged mice.

Silva MJ, Brodt MD, Lynch MA, Stephens AL, Wood DJ, Civitelli R.

PLoS One. 2012;7(4):e34980. doi: 10.1371/journal.pone.0034980. Epub 2012 Apr 13.


Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors.

Gonzalez-Nieto D, Li L, Kohler A, Ghiaur G, Ishikawa E, Sengupta A, Madhu M, Arnett JL, Santho RA, Dunn SK, Fishman GI, Gutstein DE, Civitelli R, Barrio LC, Gunzer M, Cancelas JA.

Blood. 2012 May 31;119(22):5144-54. doi: 10.1182/blood-2011-07-368506. Epub 2012 Apr 12.


N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells.

Greenbaum AM, Revollo LD, Woloszynek JR, Civitelli R, Link DC.

Blood. 2012 Jul 12;120(2):295-302. doi: 10.1182/blood-2011-09-377457. Epub 2012 Feb 9.


Calcium and phosphate homeostasis: concerted interplay of new regulators.

Civitelli R, Ziambaras K.

J Endocrinol Invest. 2011 Jul;34(7 Suppl):3-7. Review.


Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis.

Grimston SK, Goldberg DB, Watkins M, Brodt MD, Silva MJ, Civitelli R.

J Bone Miner Res. 2011 Sep;26(9):2151-60. doi: 10.1002/jbmr.425.


Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling.

Watkins M, Grimston SK, Norris JY, Guillotin B, Shaw A, Beniash E, Civitelli R.

Mol Biol Cell. 2011 Apr 15;22(8):1240-51. doi: 10.1091/mbc.E10-07-0571. Epub 2011 Feb 23.


Low-magnitude whole-body vibration does not enhance the anabolic skeletal effects of intermittent PTH in adult mice.

Lynch MA, Brodt MD, Stephens AL, Civitelli R, Silva MJ.

J Orthop Res. 2011 Apr;29(4):465-72. doi: 10.1002/jor.21280. Epub 2010 Nov 8.


One-year effects of vitamin D and calcium supplementation on chronic periodontitis.

Garcia MN, Hildebolt CF, Miley DD, Dixon DA, Couture RA, Spearie CL, Langenwalter EM, Shannon WD, Deych E, Mueller C, Civitelli R.

J Periodontol. 2011 Jan;82(1):25-32. doi: 10.1902/jop.2010.100207. Epub 2010 Sep 1.


N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms.

Di Benedetto A, Watkins M, Grimston S, Salazar V, Donsante C, Mbalaviele G, Radice GL, Civitelli R.

J Cell Sci. 2010 Aug 1;123(Pt 15):2640-8. doi: 10.1242/jcs.067777. Epub 2010 Jul 6.


Microfibril-associated glycoprotein-1, an extracellular matrix regulator of bone remodeling.

Craft CS, Zou W, Watkins M, Grimston S, Brodt MD, Broekelmann TJ, Weinbaum JS, Teitelbaum SL, Pierce RA, Civitelli R, Silva MJ, Mecham RP.

J Biol Chem. 2010 Jul 30;285(31):23858-67. doi: 10.1074/jbc.M110.113019. Epub 2010 May 25.


Cross-sectional study of vitamin D and calcium supplementation effects on chronic periodontitis.

Miley DD, Garcia MN, Hildebolt CF, Shannon WD, Couture RA, Anderson Spearie CL, Dixon DA, Langenwalter EM, Mueller C, Civitelli R.

J Periodontol. 2009 Sep;80(9):1433-9. doi: 10.1902/jop.2009.090077.

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