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Items: 1 to 50 of 196


The role of Olfaction in MCH-regulated spontaneous maternal responses.

Alhassen L, Phan A, Alhassen W, Nguyen P, Lo A, Shaharuddin H, Sanathara N, Civelli O, Alachkar A.

Brain Res. 2019 Sep 15;1719:71-76. doi: 10.1016/j.brainres.2019.05.021. Epub 2019 May 20.


The History of N/OFQ and the NOP Receptor.

Reinscheid RK, Civelli O.

Handb Exp Pharmacol. 2019;254:3-16. doi: 10.1007/164_2018_195.


Receptor-specific crosstalk between prostanoid E receptor 3 and bombesin receptor subtype 3.

Zhang Y, Liu Y, Wu L, Fan C, Wang Z, Zhang X, Alachkar A, Liang X, Civelli O.

FASEB J. 2018 Jun;32(6):3184-3192. doi: 10.1096/fj.201700337RR. Epub 2018 Jan 22.


Melanin concentrating hormone modulates oxytocin-mediated marble burying.

Sanathara NM, Garau C, Alachkar A, Wang L, Wang Z, Nishimori K, Xu X, Civelli O.

Neuropharmacology. 2018 Jan;128:22-32. doi: 10.1016/j.neuropharm.2017.09.008. Epub 2017 Sep 6.


Prenatal one-carbon metabolism dysregulation programs schizophrenia-like deficits.

Alachkar A, Wang L, Yoshimura R, Hamzeh AR, Wang Z, Sanathara N, Lee SM, Xu X, Abbott GW, Civelli O.

Mol Psychiatry. 2018 Feb;23(2):282-294. doi: 10.1038/mp.2017.164. Epub 2017 Aug 15.


The Antinociceptive Properties of the Corydalis yanhusuo Extract.

Wang L, Zhang Y, Wang Z, Gong N, Kweon TD, Vo B, Wang C, Zhang X, Chung JY, Alachkar A, Liang X, Luo DZ, Civelli O.

PLoS One. 2016 Sep 13;11(9):e0162875. doi: 10.1371/journal.pone.0162875. eCollection 2016.


Inactivation of the melanin concentrating hormone system impairs maternal behavior.

Alachkar A, Alhassen L, Wang Z, Wang L, Onouye K, Sanathara N, Civelli O.

Eur Neuropsychopharmacol. 2016 Nov;26(11):1826-1835. doi: 10.1016/j.euroneuro.2016.08.014. Epub 2016 Sep 9.


Hydroxycinnamic acid amides from Scopolia tangutica inhibit the activity of M1 muscarinic acetylcholine receptor in vitro.

Zhang Y, Long Z, Guo Z, Wang Z, Zhang X, Ye RD, Liang X, Civelli O.

Fitoterapia. 2016 Jan;108:9-12. doi: 10.1016/j.fitote.2015.11.007. Epub 2015 Nov 14.


A Methionine-Induced Animal Model of Schizophrenia: Face and Predictive Validity.

Wang L, Alachkar A, Sanathara N, Belluzzi JD, Wang Z, Civelli O.

Int J Neuropsychopharmacol. 2015 May 19;18(12). pii: pyv054. doi: 10.1093/ijnp/pyv054.


Amide alkaloids from Scopolia tangutica.

Long Z, Zhang Y, Guo Z, Wang L, Xue X, Zhang X, Wang S, Wang Z, Civelli O, Liang X.

Planta Med. 2014 Aug;80(13):1124-30. doi: 10.1055/s-0034-1382961. Epub 2014 Aug 15.


Discovery of N-methyltetrahydroprotoberberines with κ-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography.

Zhang Y, Wang C, Guo Z, Zhang X, Wang Z, Liang X, Civelli O.

J Ethnopharmacol. 2014 Sep 29;155(3):1597-602. doi: 10.1016/j.jep.2014.07.057. Epub 2014 Aug 6.


Identification of neuropeptide receptors expressed by melanin-concentrating hormone neurons.

Parks GS, Wang L, Wang Z, Civelli O.

J Comp Neurol. 2014 Dec 1;522(17):3817-33. doi: 10.1002/cne.23642. Epub 2014 Jul 17.


Histamine inhibits the melanin-concentrating hormone system: implications for sleep and arousal.

Parks GS, Olivas ND, Ikrar T, Sanathara NM, Wang L, Wang Z, Civelli O, Xu X.

J Physiol. 2014 May 15;592(10):2183-96. doi: 10.1113/jphysiol.2013.268771. Epub 2014 Mar 17.


A novel analgesic isolated from a traditional Chinese medicine.

Zhang Y, Wang C, Wang L, Parks GS, Zhang X, Guo Z, Ke Y, Li KW, Kim MK, Vo B, Borrelli E, Ge G, Yang L, Wang Z, Garcia-Fuster MJ, Luo ZD, Liang X, Civelli O.

Curr Biol. 2014 Jan 20;24(2):117-23. doi: 10.1016/j.cub.2013.11.039. Epub 2014 Jan 2.


Gait disorders in parkinsonian monkeys with pedunculopontine nucleus lesions: a tale of two systems.

Grabli D, Karachi C, Folgoas E, Monfort M, Tande D, Clark S, Civelli O, Hirsch EC, François C.

J Neurosci. 2013 Jul 17;33(29):11986-93. doi: 10.1523/JNEUROSCI.1568-13.2013.


Optimization and Characterization of a Second Antagonist for G-protein Coupled Receptor 7 (GPR7).

Guerrero M, Urbano M, Wang Z, Zhao J, Velaparthi S, Schaeffer MT, Brown SJ, Saldanha SA, Chase P, Ferguson J, Hodder P, Rosen H, Civelli O, Roberts E.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.


MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro.

Hopf FW, Seif T, Chung S, Civelli O.

PeerJ. 2013 Apr 9;1:e61. doi: 10.7717/peerj.61. Print 2013.


Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7).

Urbano M, Guerrero M, Zhao J, Velaparthi S, Saldanha SA, Chase P, Wang Z, Civelli O, Hodder P, Schaeffer MT, Brown S, Rosen H, Roberts E.

Bioorg Med Chem Lett. 2012 Dec 1;22(23):7135-41. doi: 10.1016/j.bmcl.2012.09.074. Epub 2012 Oct 2.


Orphan GPCRs and neuromodulation.

Civelli O.

Neuron. 2012 Oct 4;76(1):12-21. doi: 10.1016/j.neuron.2012.09.009. Review.


Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function.

Chung S, Liao XH, Di Cosmo C, Van Sande J, Wang Z, Refetoff S, Civelli O.

Endocrinology. 2012 Dec;153(12):6145-54. doi: 10.1210/en.2011-1435. Epub 2012 Sep 28.


G protein-coupled receptor deorphanizations.

Civelli O, Reinscheid RK, Zhang Y, Wang Z, Fredriksson R, Schiöth HB.

Annu Rev Pharmacol Toxicol. 2013;53:127-46. doi: 10.1146/annurev-pharmtox-010611-134548. Epub 2012 Sep 28. Review.


Anatomical characterization of bombesin receptor subtype-3 mRNA expression in the rodent central nervous system.

Zhang L, Parks GS, Wang Z, Wang L, Lew M, Civelli O.

J Comp Neurol. 2013 Apr 1;521(5):1020-39. doi: 10.1002/cne.23216.


Optimization and Characterization of an Antagonist for G-Protein Coupled Receptor 7 (GPR7).

Guerrero M, Urbano M, Wang Z, Zhao J, Velaparthi S, Schaeffer MT, Brown SJ, Saldanha SA, Chase P, Ferguson J, Civelli O, Roberts E, Hodder P, Rosen H.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Oct 13 [updated 2011 Nov 21].


BmK-YA, an enkephalin-like peptide in scorpion venom.

Zhang Y, Xu J, Wang Z, Zhang X, Liang X, Civelli O.

PLoS One. 2012;7(7):e40417. doi: 10.1371/journal.pone.0040417. Epub 2012 Jul 9.


The melanin-concentrating hormone (MCH) system in an animal model of depression-like behavior.

García-Fuster MJ, Parks GS, Clinton SM, Watson SJ, Akil H, Civelli O.

Eur Neuropsychopharmacol. 2012 Aug;22(8):607-13. doi: 10.1016/j.euroneuro.2011.12.001. Epub 2011 Dec 29.


Study on the activation of the opioid receptors by a set of morphine derivatives in a well-defined assay system.

Zhang Y, Wang Z, Cox DP, Civelli O.

Neurochem Res. 2012 Feb;37(2):410-6. doi: 10.1007/s11064-011-0627-7. Epub 2011 Oct 16.


The melanin-concentrating hormone (MCH) system modulates behaviors associated with psychiatric disorders.

Chung S, Verheij MM, Hesseling P, van Vugt RW, Buell M, Belluzzi JD, Geyer MA, Martens GJ, Civelli O.

PLoS One. 2011;6(7):e19286. doi: 10.1371/journal.pone.0019286. Epub 2011 Jul 19.


Novel neuropeptides as ligands of orphan G protein-coupled receptors.

Zhang Y, Wang Z, Parks GS, Civelli O.

Curr Pharm Des. 2011;17(25):2626-31. Review.


Mice lacking Melanin Concentrating Hormone 1 receptor are resistant to seizures.

Parks GS, Okumura SM, Gohil K, Civelli O.

Neurosci Lett. 2010 Oct 29;484(2):104-7. doi: 10.1016/j.neulet.2010.08.018. Epub 2010 Aug 13.


Anxiolytic effects of the MCH1R antagonist TPI 1361-17.

Lee C, Parks GS, Civelli O.

J Mol Neurosci. 2011 Feb;43(2):132-7. doi: 10.1007/s12031-010-9425-y. Epub 2010 Jul 16.


Recent updates on the melanin-concentrating hormone (MCH) and its receptor system: lessons from MCH1R antagonists.

Chung S, Parks GS, Lee C, Civelli O.

J Mol Neurosci. 2011 Jan;43(1):115-21. doi: 10.1007/s12031-010-9411-4. Epub 2010 Jun 26. Review.


Acute homeostatic responses to increased fat consumption in MCH1R knockout mice.

Chung S, Wong T, Nagasaki H, Civelli O.

J Mol Neurosci. 2010 Nov;42(3):459-63. doi: 10.1007/s12031-010-9358-5. Epub 2010 Apr 22.


MCH receptors/gene structure-in vivo expression.

Chung S, Saito Y, Civelli O.

Peptides. 2009 Nov;30(11):1985-9. doi: 10.1016/j.peptides.2009.07.017. Epub 2009 Aug 6. Review.


Pharmacological characterization of a selective agonist for bombesin receptor subtype-3.

Zhang L, Nothacker HP, Wang Z, Bohn LM, Civelli O.

Biochem Biophys Res Commun. 2009 Sep 18;387(2):283-8. doi: 10.1016/j.bbrc.2009.07.006. Epub 2009 Jul 4.


The melanin-concentrating hormone system modulates cocaine reward.

Chung S, Hopf FW, Nagasaki H, Li CY, Belluzzi JD, Bonci A, Civelli O.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6772-7. doi: 10.1073/pnas.0811331106. Epub 2009 Apr 2.


The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries.

Nagasaki H, Chung S, Dooley CT, Wang Z, Li C, Saito Y, Clark SD, Houghten RA, Civelli O.

Eur J Pharmacol. 2009 Jan 14;602(2-3):194-202. doi: 10.1016/j.ejphar.2008.10.068. Epub 2008 Nov 17.


Orphan G protein-coupled receptors and novel neuropeptides. Introduction.

Civelli O, Zhou QY.

Results Probl Cell Differ. 2008;46:v-vi. No abstract available.


Biochemical roles of the oligosaccharide chains in thyrostimulin, a heterodimeric hormone of glycoprotein hormone subunits alpha 2 (GPA2) and beta 5 (GPB5).

Okajima Y, Nagasaki H, Suzuki C, Suga H, Ozaki N, Arima H, Hamada Y, Civelli O, Oiso Y.

Regul Pept. 2008 Jun 5;148(1-3):62-7. doi: 10.1016/j.regpep.2008.03.002. Epub 2008 Mar 18.


The orphanin FQ/nociceptin (OFQ/N) system.

Civelli O.

Results Probl Cell Differ. 2008;46:1-25. doi: 10.1007/400_2007_057. Review.


Orphan GPCR research.

Chung S, Funakoshi T, Civelli O.

Br J Pharmacol. 2008 Mar;153 Suppl 1:S339-46. Epub 2007 Dec 10. Review.


Fusion of diphtheria toxin and urotensin II produces a neurotoxin selective for cholinergic neurons in the rat mesopontine tegmentum.

Clark SD, Alderson HL, Winn P, Latimer MP, Nothacker HP, Civelli O.

J Neurochem. 2007 Jul;102(1):112-20. Epub 2007 Apr 10.


A Drosophila adenosine receptor activates cAMP and calcium signaling.

Dolezelova E, Nothacker HP, Civelli O, Bryant PJ, Zurovec M.

Insect Biochem Mol Biol. 2007 Apr;37(4):318-29. Epub 2007 Jan 5.


Orphanin FQ/nociceptin interacts with the basolateral amygdala noradrenergic system in memory consolidation.

Roozendaal B, Lengvilas R, McGaugh JL, Civelli O, Reinscheid RK.

Learn Mem. 2007 Jan 3;14(1-2):29-35. Print 2007 Jan-Feb.


Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain.

Xu YL, Gall CM, Jackson VR, Civelli O, Reinscheid RK.

J Comp Neurol. 2007 Jan 1;500(1):84-102.


Differential expression of the thyrostimulin subunits, glycoprotein alpha2 and beta5 in the rat pituitary.

Nagasaki H, Wang Z, Jackson VR, Lin S, Nothacker HP, Civelli O.

J Mol Endocrinol. 2006 Aug;37(1):39-50.


Orphan neuropeptides. Novel neuropeptides modulating sleep or feeding.

Chung S, Civelli O.

Neuropeptides. 2006 Aug;40(4):233-43. Epub 2006 Jun 30. Review.


A study of the rat neuropeptide B/neuropeptide W system using in situ techniques.

Jackson VR, Lin SH, Wang Z, Nothacker HP, Civelli O.

J Comp Neurol. 2006 Jul 20;497(3):367-83.


GPR39 receptor expression in the mouse brain.

Jackson VR, Nothacker HP, Civelli O.

Neuroreport. 2006 May 29;17(8):813-6.


Salusin beta is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1.

Wang Z, Takahashi T, Saito Y, Nagasaki H, Ly NK, Nothacker HP, Reinscheid RK, Yang J, Chang JK, Shichiri M, Civelli O.

Eur J Pharmacol. 2006 Jun 13;539(3):145-50. Epub 2006 Apr 5.


Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance.

Chung S, Pohl S, Zeng J, Civelli O, Reinscheid RK.

J Pharmacol Exp Ther. 2006 Jul;318(1):262-7. Epub 2006 Apr 4.


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