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Items: 7


Signalling in response to sub-picomolar concentrations of active compounds: Pushing the boundaries of GPCR sensitivity.

Civciristov S, Halls ML.

Br J Pharmacol. 2019 Feb 22. doi: 10.1111/bph.14636. [Epub ahead of print] Review.


Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations.

Civciristov S, Ellisdon AM, Suderman R, Pon CK, Evans BA, Kleifeld O, Charlton SJ, Hlavacek WS, Canals M, Halls ML.

Sci Signal. 2018 Oct 9;11(551). pii: eaan1188. doi: 10.1126/scisignal.aan1188.


Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling.

Halls ML, Yeatman HR, Nowell CJ, Thompson GL, Gondin AB, Civciristov S, Bunnett NW, Lambert NA, Poole DP, Canals M.

Sci Signal. 2016 Feb 9;9(414):ra16. doi: 10.1126/scisignal.aac9177.


SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda.

Huang N, Civciristov S, Hawkins CJ, Clem RJ.

Insect Biochem Mol Biol. 2013 May;43(5):444-54. doi: 10.1016/j.ibmb.2013.02.005. Epub 2013 Mar 5.


Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria.

Brand IL, Civciristov S, Taylor NL, Talbo GH, Pantaki-Eimany D, Levina V, Clem RJ, Perugini MA, Kvansakul M, Hawkins CJ.

PLoS One. 2012;7(6):e39248. doi: 10.1371/journal.pone.0039248. Epub 2012 Jun 14.


Functional and biochemical characterization of the baculovirus caspase inhibitor MaviP35.

Brand IL, Green MM, Civciristov S, Pantaki-Eimany D, George C, Gort TR, Huang N, Clem RJ, Hawkins CJ.

Cell Death Dis. 2011 Dec 15;2:e242. doi: 10.1038/cddis.2011.127.


The reducible complexity of a mitochondrial molecular machine.

Clements A, Bursac D, Gatsos X, Perry AJ, Civciristov S, Celik N, Likic VA, Poggio S, Jacobs-Wagner C, Strugnell RA, Lithgow T.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15791-5. doi: 10.1073/pnas.0908264106. Epub 2009 Aug 26.

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