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Items: 1 to 50 of 92

1.

Stability and profiling of urinary microRNAs in healthy cats and cats with pyelonephritis or other urological conditions.

Jessen LR, Nielsen LN, Kieler IN, Langhorn R, Reezigt BJ, Cirera S.

J Vet Intern Med. 2019 Nov 13. doi: 10.1111/jvim.15628. [Epub ahead of print]

PMID:
31721298
2.

Evaluation of fecal microRNA stability in healthy cats.

Lyngby JG, Kristensen AT, Fredholm M, Nielsen LN, Cirera S.

Vet Clin Pathol. 2019 Sep;48(3):455-460. doi: 10.1111/vcp.12757. Epub 2019 Jun 26.

PMID:
31241203
3.

AU Content in the MicroRNA Sequence Influences its Stability after Heat Treatment.

López AG, Brogaard L, Heegaard PMH, Cirera S, Skovgaard K.

Microrna. 2019;8(3):216-222. doi: 10.2174/2211536608666190131102252.

PMID:
30706831
4.

A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits.

Cirera S, Clop A, Jacobsen MJ, Guerin M, Lesnik P, Jørgensen CB, Fredholm M, Karlskov-Mortensen P.

Anim Genet. 2018 Apr;49(2):110-118. doi: 10.1111/age.12641. Epub 2018 Feb 14.

PMID:
29441627
5.

Evaluation of microRNA stability in feces from healthy dogs.

Cirera S, Willumsen LM, Johansen TT, Nielsen LN.

Vet Clin Pathol. 2018 Mar;47(1):115-121. doi: 10.1111/vcp.12566. Epub 2018 Feb 2.

PMID:
29393972
6.

Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs.

Mentzel CMJ, Cardoso TF, Pipper CB, Jacobsen MJ, Jørgensen CB, Cirera S, Fredholm M.

Mol Genet Genomics. 2018 Feb;293(1):129-136. doi: 10.1007/s00438-017-1369-2. Epub 2017 Sep 14.

PMID:
28913560
7.

Haplotypes on pig chromosome 3 distinguish metabolically healthy from unhealthy obese individuals.

Frederiksen SD, Karlskov-Mortensen P, Pant SD, Guerin M, Lesnik P, Jørgensen CB, Cirera S, Bruun CS, Mark T, Fredholm M.

PLoS One. 2017 Jun 1;12(6):e0178828. doi: 10.1371/journal.pone.0178828. eCollection 2017.

8.

Fat and carbohydrate content in the diet induces drastic changes in gene expression in young Göttingen minipigs.

Mentzel CMJ, Cardoso TF, Lex AMJ, Sørensen DB, Fredholm M, Cirera S.

Mamm Genome. 2017 Jun;28(5-6):166-175. doi: 10.1007/s00335-017-9690-y. Epub 2017 Apr 10.

PMID:
28396939
9.

Evaluation of microRNA Stability in Plasma and Serum from Healthy Dogs.

Enelund L, Nielsen LN, Cirera S.

Microrna. 2017;6(1):42-52. doi: 10.2174/2211536606666170113124114.

PMID:
28088915
10.

FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome.

Wucher V, Legeai F, Hédan B, Rizk G, Lagoutte L, Leeb T, Jagannathan V, Cadieu E, David A, Lohi H, Cirera S, Fredholm M, Botherel N, Leegwater PAJ, Le Béguec C, Fieten H, Johnson J, Alföldi J, André C, Lindblad-Toh K, Hitte C, Derrien T.

Nucleic Acids Res. 2017 May 5;45(8):e57. doi: 10.1093/nar/gkw1306.

11.

Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells.

Secher JO, Ceylan A, Mazzoni G, Mashayekhi K, Li T, Muenthaisong S, Nielsen TT, Li D, Li S, Petkov S, Cirera S, Luo Y, Thombs L, Kadarmideen HN, Dinnyes A, Bolund L, Roelen BA, Schmidt M, Callesen H, Hyttel P, Freude KK.

Mol Reprod Dev. 2017 Mar;84(3):229-245. doi: 10.1002/mrd.22771.

12.

Transcriptional immune response in mesenteric lymph nodes in pigs with different levels of resistance to Ascaris suum.

Skallerup P, Nejsum P, Cirera S, Skovgaard K, Pipper CB, Fredholm M, Jørgensen CB, Thamsborg SM.

Acta Parasitol. 2017 Mar 1;62(1):141-153. doi: 10.1515/ap-2017-0017.

PMID:
28030356
13.

Joint Profiling of miRNAs and mRNAs Reveals miRNA Mediated Gene Regulation in the Göttingen Minipig Obesity Model.

Mentzel CM, Alkan F, Keinicke H, Jacobsen MJ, Gorodkin J, Fredholm M, Cirera S.

PLoS One. 2016 Nov 30;11(11):e0167285. doi: 10.1371/journal.pone.0167285. eCollection 2016.

14.

Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes.

Clop A, Sharaf A, Castelló A, Ramos-Onsins S, Cirera S, Mercadé A, Derdak S, Beltran S, Huisman A, Fredholm M, van As P, Sánchez A.

BMC Genomics. 2016 Aug 26;17:685. doi: 10.1186/s12864-016-2972-z.

15.

The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF.

Zhou S, Ochalek A, Szczesna K, Avci HX, Kobolák J, Varga E, Rasmussen M, Holst B, Cirera S, Hyttel P, Freude KK, Dinnyés A.

Differentiation. 2016 Oct - Nov;92(4):183-194. doi: 10.1016/j.diff.2016.06.002. Epub 2016 Jun 16.

PMID:
27321088
16.

Hepatic expression of inflammatory genes and microRNAs in pigs with high "cholesteryl ester transfer protein" (CETP) activity.

Cirera S, Tørsleff BC, Ritz C, Fredholm M, Heegaard PM, Skovgaard K.

Mamm Genome. 2016 Oct;27(9-10):503-10. doi: 10.1007/s00335-016-9649-4. Epub 2016 May 30.

PMID:
27240589
17.

A large insertion in intron 2 of the TYRP1 gene associated with American Palomino phenotype in American mink.

Cirera S, Markakis MN, Kristiansen T, Vissenberg K, Fredholm M, Christensen K, Anistoroaei R.

Mamm Genome. 2016 Apr;27(3-4):135-43. doi: 10.1007/s00335-016-9620-4. Epub 2016 Feb 17.

PMID:
26886941
18.

Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation.

Zhou S, Szczesna K, Ochalek A, Kobolák J, Varga E, Nemes C, Chandrasekaran A, Rasmussen M, Cirera S, Hyttel P, Dinnyés A, Freude KK, Avci HX.

Stem Cells Int. 2016;2016:4937689. doi: 10.1155/2016/4937689. Epub 2015 Dec 21.

19.

Circulating let-7g is down-regulated in Bernese Mountain dogs with disseminated histiocytic sarcoma and carcinomas - a prospective study.

Børresen B, Nielsen LN, Jessen LR, Kristensen AT, Fredholm M, Cirera S.

Vet Comp Oncol. 2017 Jun;15(2):525-533. doi: 10.1111/vco.12196. Epub 2016 Jan 21.

PMID:
26792388
20.

Transcriptional analysis of porcine intestinal mucosa infected with Salmonella Typhimurium revealed a massive inflammatory response and disruption of bile acid absorption in ileum.

Uribe JH, Collado-Romero M, Zaldívar-López S, Arce C, Bautista R, Carvajal A, Cirera S, Claros MG, Garrido JJ.

Vet Res. 2016 Jan 7;47:11. doi: 10.1186/s13567-015-0286-9.

21.

Physical training and weight loss in dogs lead to transcriptional changes in genes involved in the glucose-transport pathway in muscle and adipose tissues.

Herrera Uribe J, Vitger AD, Ritz C, Fredholm M, Bjørnvad CR, Cirera S.

Vet J. 2016 Feb;208:22-7. doi: 10.1016/j.tvjl.2015.11.002. Epub 2015 Nov 10.

PMID:
26701817
22.

Comparison of American mink embryonic stem and induced pluripotent stem cell transcriptomes.

Menzorov AG, Matveeva NM, Markakis MN, Fishman VS, Christensen K, Khabarova AA, Pristyazhnyuk IE, Kizilova EA, Cirera S, Anistoroaei R, Serov OL.

BMC Genomics. 2015;16 Suppl 13:S6. doi: 10.1186/1471-2164-16-S13-S6. Epub 2015 Dec 16.

23.

An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.

Kogelman LJ, Zhernakova DV, Westra HJ, Cirera S, Fredholm M, Franke L, Kadarmideen HN.

Genome Med. 2015 Oct 20;7:105. doi: 10.1186/s13073-015-0229-0.

24.

Comparative Analyses of QTLs Influencing Obesity and Metabolic Phenotypes in Pigs and Humans.

Pant SD, Karlskov-Mortensen P, Jacobsen MJ, Cirera S, Kogelman LJ, Bruun CS, Mark T, Jørgensen CB, Grarup N, Appel EV, Galjatovic EA, Hansen T, Pedersen O, Guerin M, Huby T, Lesnik P, Meuwissen TH, Kadarmideen HN, Fredholm M.

PLoS One. 2015 Sep 8;10(9):e0137356. doi: 10.1371/journal.pone.0137356. eCollection 2015.

25.

Expression study of GLUT4 translocation-related genes in a porcine pre-diabetic model.

Kristensen T, Fredholm M, Cirera S.

Mamm Genome. 2015 Dec;26(11-12):650-7. doi: 10.1007/s00335-015-9601-z. Epub 2015 Sep 7.

PMID:
26346769
26.

Gender and Obesity Specific MicroRNA Expression in Adipose Tissue from Lean and Obese Pigs.

Mentzel CM, Anthon C, Jacobsen MJ, Karlskov-Mortensen P, Bruun CS, Jørgensen CB, Gorodkin J, Cirera S, Fredholm M.

PLoS One. 2015 Jul 29;10(7):e0131650. doi: 10.1371/journal.pone.0131650. eCollection 2015.

27.

Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease.

Cremer SE, Moesgaard SG, Rasmussen CE, Zois NE, Falk T, Reimann MJ, Cirera S, Aupperle H, Oyama MA, Olsen LH.

Res Vet Sci. 2015 Jun;100:197-206. doi: 10.1016/j.rvsc.2015.03.020. Epub 2015 Mar 19.

PMID:
25843893
28.

Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation.

Cremer SE, Zois NE, Moesgaard SG, Ravn N, Cirera S, Honge JL, Smerup MH, Hasenkam JM, Sloth E, Leifsson PS, Falk T, Oyama MA, Orton C, Martinussen T, Olsen LH.

Vet J. 2015 Feb;203(2):192-8. doi: 10.1016/j.tvjl.2014.12.016. Epub 2014 Dec 23.

PMID:
25599900
29.

Wet-lab tested microRNA assays for qPCR studies with SYBR® Green and DNA primers in pig tissues.

Mentzel CM, Skovgaard K, Córdoba S, Herrera Uribe J, Busk PK, Cirera S.

Microrna. 2014;3(3):174-88.

PMID:
25544471
30.

Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine model.

Kogelman LJ, Cirera S, Zhernakova DV, Fredholm M, Franke L, Kadarmideen HN.

BMC Med Genomics. 2014 Sep 30;7:57. doi: 10.1186/1755-8794-7-57.

31.

Quantification of miRNAs by a simple and specific qPCR method.

Cirera S, Busk PK.

Methods Mol Biol. 2014;1182:73-81. doi: 10.1007/978-1-4939-1062-5_7.

PMID:
25055902
32.

Strong association between activated valvular interstitial cells and histopathological lesions in porcine model of induced mitral regurgitation.

Cremer SE, Zois NE, Moesgaard SG, Ravn N, Cirera S, Honge JL, Smerup MH, Hasenkam JM, Sloth E, Leifsson PS, Falk T, Oyama MA, Orton C, Martinussen T, Olsen LH.

Int J Cardiol. 2014 Jun 15;174(2):443-6. doi: 10.1016/j.ijcard.2014.04.022. Epub 2014 Apr 13. No abstract available.

PMID:
24768395
33.

Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs.

Boonen HC, Moesgaard SG, Birck MM, Christoffersen BO, Cirera S, Heegaard PM, Højbøge TR, Jensen LJ, Mortensen A, Olsen LH, Sheykhzade M, Tang J, Lykkesfeldt J.

Pflugers Arch. 2014 Dec;466(12):2167-76. doi: 10.1007/s00424-014-1486-2. Epub 2014 Mar 5.

PMID:
24590510
34.

Characterization of a small auxin-up RNA (SAUR)-like gene involved in Arabidopsis thaliana development.

Markakis MN, Boron AK, Van Loock B, Saini K, Cirera S, Verbelen JP, Vissenberg K.

PLoS One. 2013 Nov 27;8(11):e82596. doi: 10.1371/journal.pone.0082596. eCollection 2013.

35.

Highly efficient method for isolation of total RNA from adipose tissue.

Cirera S.

BMC Res Notes. 2013 Nov 18;6:472. doi: 10.1186/1756-0500-6-472.

36.

Extensive changes in innate immune gene expression in obese Göttingen minipigs do not lead to changes in concentrations of circulating cytokines and acute phase proteins.

Rødgaard T, Skovgaard K, Moesgaard SG, Cirera S, Christoffersen BØ, Heegaard PM.

Anim Genet. 2014 Feb;45(1):67-73. doi: 10.1111/age.12090. Epub 2013 Sep 25.

PMID:
24106888
37.

Functional characterization of a porcine emphysema model.

Bruun CS, Jensen LK, Leifsson PS, Nielsen J, Cirera S, Jørgensen CB, Jensen HE, Fredholm M.

Lung. 2013 Dec;191(6):669-75. doi: 10.1007/s00408-013-9504-2. Epub 2013 Sep 17.

PMID:
24043489
38.

Expression studies of six human obesity-related genes in seven tissues from divergent pig breeds.

Cirera S, Jensen MS, Elbrønd VS, Moesgaard SG, Christoffersen BØ, Kadarmideen HN, Skovgaard K, Bruun CV, Karlskov-Mortensen P, Jørgensen CB, Fredholm M.

Anim Genet. 2014 Feb;45(1):59-66. doi: 10.1111/age.12082. Epub 2013 Aug 23.

PMID:
24033492
39.

Plasma proANP and SDMA and microRNAs are associated with chronic mitral regurgitation in a pig model.

Cirera S, Moesgaard SG, Zois NE, Ravn N, Goetze JP, Cremer SE, Teerlink T, Leifsson PS, Honge JL, Hasenkam JM, Olsen LH.

Endocr Connect. 2013 Sep 24;2(3):161-71. doi: 10.1530/EC-13-0051. Print 2013.

40.

New insights into the melanophilin (MLPH) gene controlling coat color phenotypes in American mink.

Cirera S, Markakis MN, Christensen K, Anistoroaei R.

Gene. 2013 Sep 15;527(1):48-54. doi: 10.1016/j.gene.2013.05.047. Epub 2013 Jun 6.

PMID:
23747352
41.

An f2 pig resource population as a model for genetic studies of obesity and obesity-related diseases in humans: design and genetic parameters.

Kogelman LJ, Kadarmideen HN, Mark T, Karlskov-Mortensen P, Bruun CS, Cirera S, Jacobsen MJ, Jørgensen CB, Fredholm M.

Front Genet. 2013 Mar 18;4:29. doi: 10.3389/fgene.2013.00029. eCollection 2013.

42.

Characterisation of gut microbiota in Ossabaw and Göttingen minipigs as models of obesity and metabolic syndrome.

Pedersen R, Ingerslev HC, Sturek M, Alloosh M, Cirera S, Christoffersen BØ, Moesgaard SG, Larsen N, Boye M.

PLoS One. 2013;8(2):e56612. doi: 10.1371/journal.pone.0056612. Epub 2013 Feb 20.

43.

Expression of innate immune genes, proteins and microRNAs in lung tissue of pigs infected experimentally with influenza virus (H1N2).

Skovgaard K, Cirera S, Vasby D, Podolska A, Breum SØ, Dürrwald R, Schlegel M, Heegaard PM.

Innate Immun. 2013 Oct;19(5):531-44. doi: 10.1177/1753425912473668. Epub 2013 Feb 12.

PMID:
23405029
44.

Potential role of the porcine superoxide dismutase 1 (SOD1) gene in pig reproduction.

Bjerre D, Madsen LB, Mark T, Cirera S, Larsen K, Jørgensen CB, Fredholm M.

Anim Biotechnol. 2013 Jan;24(1):1-9. doi: 10.1080/10495398.2012.723083.

PMID:
23394364
45.

A Gly98Val mutation in the N-Myc downstream regulated gene 1 (NDRG1) in Alaskan Malamutes with polyneuropathy.

Bruun CS, Jäderlund KH, Berendt M, Jensen KB, Spodsberg EH, Gredal H, Shelton GD, Mickelson JR, Minor KM, Lohi H, Bjerkås I, Stigen O, Espenes A, Rohdin C, Edlund R, Ohlsson J, Cizinauskas S, Leifsson PS, Drögemüller C, Moe L, Cirera S, Fredholm M.

PLoS One. 2013;8(2):e54547. doi: 10.1371/journal.pone.0054547. Epub 2013 Feb 5.

46.

Orosomucoid expression profiles in liver, adipose tissues and serum of lean and obese domestic pigs, Göttingen minipigs and Ossabaw minipigs.

Rødgaard T, Stagsted J, Christoffersen BØ, Cirera S, Moesgaard SG, Sturek M, Alloosh M, Heegaard PM.

Vet Immunol Immunopathol. 2013 Feb 15;151(3-4):325-30. doi: 10.1016/j.vetimm.2012.11.002. Epub 2012 Nov 27.

PMID:
23254161
47.

Profiling microRNAs in lung tissue from pigs infected with Actinobacillus pleuropneumoniae.

Podolska A, Anthon C, Bak M, Tommerup N, Skovgaard K, Heegaard PM, Gorodkin J, Cirera S, Fredholm M.

BMC Genomics. 2012 Sep 6;13:459. doi: 10.1186/1471-2164-13-459.

48.

A deletion in the bovine FANCI gene compromises fertility by causing fetal death and brachyspina.

Charlier C, Agerholm JS, Coppieters W, Karlskov-Mortensen P, Li W, de Jong G, Fasquelle C, Karim L, Cirera S, Cambisano N, Ahariz N, Mullaart E, Georges M, Fredholm M.

PLoS One. 2012;7(8):e43085. doi: 10.1371/journal.pone.0043085. Epub 2012 Aug 29.

49.

How the RNA isolation method can affect microRNA microarray results.

Podolska A, Kaczkowski B, Litman T, Fredholm M, Cirera S.

Acta Biochim Pol. 2011;58(4):535-40. Epub 2011 Dec 6.

50.

Exonization of a LINE1 fragment implicated in X-linked hypohidrotic ectodermal dysplasia in cattle.

Karlskov-Mortensen P, Cirera S, Nielsen OL, Arnbjerg J, Reibel J, Fredholm M, Agerholm JS.

Anim Genet. 2011 Dec;42(6):578-84. doi: 10.1111/j.1365-2052.2011.02192.x. Epub 2011 Apr 13.

PMID:
22034998

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