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Items: 1 to 50 of 61

1.

The POU-Domain Transcription Factor Oct-6/POU3F1 as a Regulator of Cellular Response to Genotoxic Stress.

Fionda C, Di Bona D, Kosta A, Stabile H, Santoni A, Cippitelli M.

Cancers (Basel). 2019 Jun 11;11(6). pii: E810. doi: 10.3390/cancers11060810.

2.

Activation of liver X receptor up-regulates the expression of the NKG2D ligands MICA and MICB in multiple myeloma through different molecular mechanisms.

Bilotta MT, Abruzzese MP, Molfetta R, Scarno G, Fionda C, Zingoni A, Soriani A, Garofalo T, Petrucci MT, Ricciardi MR, Paolini R, Santoni A, Cippitelli M.

FASEB J. 2019 Aug;33(8):9489-9504. doi: 10.1096/fj.201900319R. Epub 2019 May 24.

PMID:
31125275
3.

The homeobox transcription factor MEIS2 is a regulator of cancer cell survival and IMiDs activity in Multiple Myeloma: modulation by Bromodomain and Extra-Terminal (BET) protein inhibitors.

Abruzzese MP, Bilotta MT, Fionda C, Zingoni A, Soriani A, Petrucci MT, Ricciardi MR, Molfetta R, Paolini R, Santoni A, Cippitelli M.

Cell Death Dis. 2019 Apr 11;10(4):324. doi: 10.1038/s41419-019-1562-9.

4.

The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing.

Molfetta R, Milito ND, Zitti B, Lecce M, Fionda C, Cippitelli M, Santoni A, Paolini R.

Eur J Immunol. 2019 Jun;49(6):873-883. doi: 10.1002/eji.201847848. Epub 2019 Mar 27.

PMID:
30888046
5.

Key Role of the CD56lowCD16low Natural Killer Cell Subset in the Recognition and Killing of Multiple Myeloma Cells.

Vulpis E, Stabile H, Soriani A, Fionda C, Petrucci MT, Mariggio' E, Ricciardi MR, Cippitelli M, Gismondi A, Santoni A, Zingoni A.

Cancers (Basel). 2018 Nov 29;10(12). pii: E473. doi: 10.3390/cancers10120473.

6.

Translating the anti-myeloma activity of Natural Killer cells into clinical application.

Fionda C, Stabile H, Molfetta R, Soriani A, Bernardini G, Zingoni A, Gismondi A, Paolini R, Cippitelli M, Santoni A.

Cancer Treat Rev. 2018 Nov;70:255-264. doi: 10.1016/j.ctrv.2018.10.005. Epub 2018 Oct 10. Review.

PMID:
30326421
7.

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

Zingoni A, Vulpis E, Cecere F, Amendola MG, Fuerst D, Saribekyan T, Achour A, Sandalova T, Nardone I, Peri A, Soriani A, Fionda C, Mariggiò E, Petrucci MT, Ricciardi MR, Mytilineos J, Cippitelli M, Cerboni C, Santoni A.

Front Immunol. 2018 May 1;9:926. doi: 10.3389/fimmu.2018.00926. eCollection 2018.

8.

Drug-Induced Senescent Multiple Myeloma Cells Elicit NK Cell Proliferation by Direct or Exosome-Mediated IL15 Trans-Presentation.

Borrelli C, Ricci B, Vulpis E, Fionda C, Ricciardi MR, Petrucci MT, Masuelli L, Peri A, Cippitelli M, Zingoni A, Santoni A, Soriani A.

Cancer Immunol Res. 2018 Jul;6(7):860-869. doi: 10.1158/2326-6066.CIR-17-0604. Epub 2018 Apr 24.

9.

NKG2D and Its Ligands: "One for All, All for One".

Zingoni A, Molfetta R, Fionda C, Soriani A, Paolini R, Cippitelli M, Cerboni C, Santoni A.

Front Immunol. 2018 Mar 12;9:476. doi: 10.3389/fimmu.2018.00476. eCollection 2018. Review.

10.

Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance.

Zingoni A, Fionda C, Borrelli C, Cippitelli M, Santoni A, Soriani A.

Front Immunol. 2017 Sep 25;8:1194. doi: 10.3389/fimmu.2017.01194. eCollection 2017. Review.

11.

Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells.

Zitti B, Molfetta R, Fionda C, Quatrini L, Stabile H, Lecce M, de Turris V, Ricciardi MR, Petrucci MT, Cippitelli M, Gismondi A, Santoni A, Paolini R.

Sci Rep. 2017 Sep 5;7(1):10445. doi: 10.1038/s41598-017-10403-0.

12.

Toxicological Analysis of Opiates from Alternative Matrices Collected from an Exhumed Body.

Cippitelli M, Mirtella D, Ottaviani G, Tassoni G, Froldi R, Cingolani M.

J Forensic Sci. 2018 Mar;63(2):640-643. doi: 10.1111/1556-4029.13559. Epub 2017 May 18.

PMID:
28516444
13.

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis.

Vulpis E, Cecere F, Molfetta R, Soriani A, Fionda C, Peruzzi G, Caracciolo G, Palchetti S, Masuelli L, Simonelli L, D'Oro U, Abruzzese MP, Petrucci MT, Ricciardi MR, Paolini R, Cippitelli M, Santoni A, Zingoni A.

Oncoimmunology. 2017 Jan 13;6(3):e1279372. doi: 10.1080/2162402X.2017.1279372. eCollection 2017.

14.

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.

Soriani A, Borrelli C, Ricci B, Molfetta R, Zingoni A, Fionda C, Carnevale S, Abruzzese MP, Petrucci MT, Ricciardi MR, La Regina G, Di Cesare E, Lavia P, Silvestri R, Paolini R, Cippitelli M, Santoni A.

Oncoimmunology. 2016 Dec 2;6(1):e1264564. doi: 10.1080/2162402X.2016.1264564. eCollection 2017.

15.

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay.

Abruzzese MP, Bilotta MT, Fionda C, Zingoni A, Soriani A, Vulpis E, Borrelli C, Zitti B, Petrucci MT, Ricciardi MR, Molfetta R, Paolini R, Santoni A, Cippitelli M.

J Hematol Oncol. 2016 Dec 1;9(1):134.

16.

Immunoregulatory and Effector Activities of Nitric Oxide and Reactive Nitrogen Species in Cancer.

Fionda C, Abruzzese MP, Santoni A, Cippitelli M.

Curr Med Chem. 2016;23(24):2618-2636. Review.

PMID:
27464520
17.

Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression.

Pignoloni B, Fionda C, Dell'Oste V, Luganini A, Cippitelli M, Zingoni A, Landolfo S, Gribaudo G, Santoni A, Cerboni C.

J Immunol. 2016 Nov 15;197(10):4066-4078. Epub 2016 Oct 12.

18.

Determination of Drugs of Abuse in a Single Sample of Human Teeth by a Gas Chromatography-Mass Spectrometry Method.

Ottaviani G, Cameriere R, Cippitelli M, Froldi R, Tassoni G, Zampi M, Cingolani M.

J Anal Toxicol. 2017 Jan;41(1):32-36. doi: 10.1093/jat/bkw105. Epub 2016 Sep 27.

PMID:
27681340
19.

Driving under the effect of drugs: Hair analysis in order to evaluate recidivism.

Tassoni G, Cippitelli M, Mirtella D, Froldi R, Ottaviani G, Zampi M, Cingolani M.

Forensic Sci Int. 2016 Oct;267:125-128. doi: 10.1016/j.forsciint.2016.08.022. Epub 2016 Aug 23.

PMID:
27597254
20.

Targeting NKG2D and NKp30 Ligands Shedding to Improve NK Cell-Based Immunotherapy.

Zingoni A, Vulpis E, Nardone I, Soriani A, Fionda C, Cippitelli M, Santoni A.

Crit Rev Immunol. 2016;36(6):445-460. doi: 10.1615/CritRevImmunol.2017020166.

PMID:
28845754
21.

Ubiquitin-dependent endocytosis of NKG2D-DAP10 receptor complexes activates signaling and functions in human NK cells.

Quatrini L, Molfetta R, Zitti B, Peruzzi G, Fionda C, Capuano C, Galandrini R, Cippitelli M, Santoni A, Paolini R.

Sci Signal. 2015 Oct 27;8(400):ra108. doi: 10.1126/scisignal.aab2724.

PMID:
26508790
22.

Detection of Cannabinoids by ELISA and GC-MS Methods in a Hair Sample Previously Used to Detect Other Drugs of Abuse.

Tassoni G, Cippitelli M, Ottaviani G, Froldi R, Cingolani M.

J Anal Toxicol. 2016 Jul;40(6):408-13. doi: 10.1093/jat/bkv120. Epub 2015 Oct 20.

PMID:
26487640
23.

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma.

Fionda C, Abruzzese MP, Zingoni A, Cecere F, Vulpis E, Peruzzi G, Soriani A, Molfetta R, Paolini R, Ricciardi MR, Petrucci MT, Santoni A, Cippitelli M.

Oncotarget. 2015 Sep 15;6(27):23609-30.

24.

NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma.

Fionda C, Soriani A, Zingoni A, Santoni A, Cippitelli M.

Biomed Res Int. 2015;2015:178698. doi: 10.1155/2015/178698. Epub 2015 Jun 16. Review.

25.

Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells.

Zingoni A, Cecere F, Vulpis E, Fionda C, Molfetta R, Soriani A, Petrucci MT, Ricciardi MR, Fuerst D, Amendola MG, Mytilineos J, Cerboni C, Paolini R, Cippitelli M, Santoni A.

J Immunol. 2015 Jul 15;195(2):736-48. doi: 10.4049/jimmunol.1402643. Epub 2015 Jun 12.

26.

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.

Fionda C, Abruzzese MP, Zingoni A, Soriani A, Ricci B, Molfetta R, Paolini R, Santoni A, Cippitelli M.

BMC Cancer. 2015 Jan 22;15:17. doi: 10.1186/s12885-015-1023-5.

27.

Hair analysis in order to evaluate drug abuse in driver's license regranting procedures.

Tassoni G, Mirtella D, Zampi M, Ferrante L, Cippitelli M, Cognigni E, Froldi R, Cingolani M.

Forensic Sci Int. 2014 Nov;244:16-9. doi: 10.1016/j.forsciint.2014.07.025. Epub 2014 Aug 4.

PMID:
25151106
28.

Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1.

Soriani A, Iannitto ML, Ricci B, Fionda C, Malgarini G, Morrone S, Peruzzi G, Ricciardi MR, Petrucci MT, Cippitelli M, Santoni A.

J Immunol. 2014 Jul 15;193(2):950-60. doi: 10.4049/jimmunol.1400271. Epub 2014 Jun 9.

29.

HLA and killer cell immunoglobulin-like receptors influence the natural course of CMV infection.

Di Bona D, Scafidi V, Plaia A, Colomba C, Nuzzo D, Occhino C, Tuttolomondo A, Giammanco G, De Grazia S, Montalto G, Duro G, Cippitelli M, Caruso C.

J Infect Dis. 2014 Oct 1;210(7):1083-9. doi: 10.1093/infdis/jiu226. Epub 2014 Apr 15.

PMID:
24737799
30.

Unexpected variation of the codeine/morphine ratio following fatal heroin overdose.

Gambaro V, Argo A, Cippitelli M, Dell'Acqua L, Farè F, Froldi R, Guerrini K, Roda G, Rusconi C, Procaccianti P.

J Anal Toxicol. 2014 Jun;38(5):289-94. doi: 10.1093/jat/bku016. Epub 2014 Apr 11.

PMID:
24727081
31.

Determination of cytokeratins 1, 13 and 14 in oral lichen planus.

Rivarola de Gutierrez E, Innocenti AC, Cippitelli MJ, Salomón S, Vargas-Roig LM.

Med Oral Patol Oral Cir Bucal. 2014 Jul 1;19(4):e359-65.

32.

Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma.

Soriani A, Fionda C, Ricci B, Iannitto ML, Cippitelli M, Santoni A.

Oncoimmunology. 2013 Dec 1;2(12):e26663. Epub 2013 Oct 22.

33.

The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells.

Cerboni C, Fionda C, Soriani A, Zingoni A, Doria M, Cippitelli M, Santoni A.

Front Immunol. 2014 Jan 7;4:508. doi: 10.3389/fimmu.2013.00508. eCollection 2014 Jan 7. Review.

34.

Inhibition of glycogen synthase kinase-3 increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of STAT3.

Fionda C, Malgarini G, Soriani A, Zingoni A, Cecere F, Iannitto ML, Ricciardi MR, Federico V, Petrucci MT, Santoni A, Cippitelli M.

J Immunol. 2013 Jun 15;190(12):6662-72. doi: 10.4049/jimmunol.1201426. Epub 2013 May 17.

35.

IL-15 inhibits IL-7Rα expression by memory-phenotype CD8⁺ T cells in the bone marrow.

Quinci AC, Vitale S, Parretta E, Soriani A, Iannitto ML, Cippitelli M, Fionda C, Bulfone-Paus S, Santoni A, Di Rosa F.

Eur J Immunol. 2012 May;42(5):1129-39. doi: 10.1002/eji.201142019.

36.

Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation.

Fionda C, Soriani A, Malgarini G, Iannitto ML, Santoni A, Cippitelli M.

J Immunol. 2009 Oct 1;183(7):4385-94. doi: 10.4049/jimmunol.0901797. Epub 2009 Sep 11.

37.

Immobilized HIV-1 Tat protein promotes gene transfer via a transactivation-independent mechanism which requires binding of Tat to viral particles.

Nappi F, Chiozzini C, Bordignon V, Borsetti A, Bellino S, Cippitelli M, Barillari G, Caputo A, Tyagi M, Giacca M, Ensoli B.

J Gene Med. 2009 Nov;11(11):955-65. doi: 10.1002/jgm.1381.

PMID:
19653251
38.

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype.

Soriani A, Zingoni A, Cerboni C, Iannitto ML, Ricciardi MR, Di Gialleonardo V, Cippitelli M, Fionda C, Petrucci MT, Guarini A, Foà R, Santoni A.

Blood. 2009 Apr 9;113(15):3503-11. doi: 10.1182/blood-2008-08-173914. Epub 2008 Dec 19.

39.

Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes.

Fionda C, Nappi F, Piccoli M, Frati L, Santoni A, Cippitelli M.

Mol Pharmacol. 2007 Nov;72(5):1246-57. Epub 2007 Aug 2.

PMID:
17673570
40.

Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis.

Cerboni C, Zingoni A, Cippitelli M, Piccoli M, Frati L, Santoni A.

Blood. 2007 Jul 15;110(2):606-15. Epub 2007 Apr 3.

41.
42.

Oxidative stress inhibits IFN-alpha-induced antiviral gene expression by blocking the JAK-STAT pathway.

Di Bona D, Cippitelli M, Fionda C, Cammà C, Licata A, Santoni A, Craxì A.

J Hepatol. 2006 Aug;45(2):271-9. Epub 2006 Mar 9.

PMID:
16595158
43.

Stability of barbiturates in fixed tissues and formalin solutions.

Cingolani M, Cippitelli M, Froldi R, Tassoni G, Mirtella D.

J Anal Toxicol. 2005 Apr;29(3):205-8.

PMID:
15842765
44.

Hyperthermia enhances CD95-ligand gene expression in T lymphocytes.

Cippitelli M, Fionda C, Di Bona D, Piccoli M, Frati L, Santoni A.

J Immunol. 2005 Jan 1;174(1):223-32.

45.

Detection and quantitation analysis of cocaine and metabolites in fixed liver tissue and formalin solutions.

Cingolani M, Cippitelli M, Froldi R, Gambaro V, Tassoni G.

J Anal Toxicol. 2004 Jan-Feb;28(1):16-9.

PMID:
14987419
47.

Negative regulation of CD95 ligand gene expression by vitamin D3 in T lymphocytes.

Cippitelli M, Fionda C, Di Bona D, Di Rosa F, Lupo A, Piccoli M, Frati L, Santoni A.

J Immunol. 2002 Feb 1;168(3):1154-66.

48.

relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells.

Ricca A, Biroccio A, Trisciuoglio D, Cippitelli M, Zupi G, Del Bufalo D.

Br J Cancer. 2001 Dec 14;85(12):1914-21.

49.

bcl-2 over-expression enhances NF-kappaB activity and induces mmp-9 transcription in human MCF7(ADR) breast-cancer cells.

Ricca A, Biroccio A, Del Bufalo D, Mackay AR, Santoni A, Cippitelli M.

Int J Cancer. 2000 Apr 15;86(2):188-96.

50.

Vitamin D3: a transcriptional modulator of the interferon-gamma gene.

Cippitelli M, Santoni A.

Eur J Immunol. 1998 Oct;28(10):3017-30.

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