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Items: 45


The POSEIDON Criteria and Its Measure of Success Through the Eyes of Clinicians and Embryologists.

Esteves SC, Alviggi C, Humaidan P, Fischer R, Andersen CY, Conforti A, Bühler K, Sunkara SK, Polyzos NP, Galliano D, Grynberg M, Yarali H, Özbek IY, Roque M, Vuong LN, Banker M, Rienzi L, Vaiarelli A, Cimadomo D, Ubaldi FM.

Front Endocrinol (Lausanne). 2019 Nov 20;10:814. doi: 10.3389/fendo.2019.00814. eCollection 2019.


Similar miRNomic signatures characterize the follicular fluids collected after follicular and luteal phase stimulations in the same ovarian cycle.

Cimadomo D, Carmelo R, Parrotta EI, Scalise S, Santamaria G, Alviggi E, De Angelis MT, Sarro G, Vaiarelli A, Venturella R, Rienzi L, Zullo F, Ubaldi FM, Cuda G.

J Assist Reprod Genet. 2019 Nov 7. doi: 10.1007/s10815-019-01607-6. [Epub ahead of print]


Chromosome errors in human eggs shape natural fertility over reproductive life span.

Gruhn JR, Zielinska AP, Shukla V, Blanshard R, Capalbo A, Cimadomo D, Nikiforov D, Chan AC, Newnham LJ, Vogel I, Scarica C, Krapchev M, Taylor D, Kristensen SG, Cheng J, Ernst E, Bjørn AB, Colmorn LB, Blayney M, Elder K, Liss J, Hartshorne G, Grøndahl ML, Rienzi L, Ubaldi F, McCoy R, Lukaszuk K, Andersen CY, Schuh M, Hoffmann ER.

Science. 2019 Sep 27;365(6460):1466-1469. doi: 10.1126/science.aav7321.


Definition and validation of a custom protocol to detect miRNAs in the spent media after blastocyst culture: searching for biomarkers of implantation.

Cimadomo D, Rienzi L, Giancani A, Alviggi E, Dusi L, Canipari R, Noli L, Ilic D, Khalaf Y, Ubaldi FM, Capalbo A.

Hum Reprod. 2019 Sep 29;34(9):1746-1761. doi: 10.1093/humrep/dez119.


Human Blastocyst Biopsy and Vitrification.

Maggiulli R, Giancani A, Cimadomo D, Ubaldi FM, Rienzi L.

J Vis Exp. 2019 Jul 26;(149). doi: 10.3791/59625.


Management of Women With an Unexpected Low Ovarian Response to Gonadotropin.

Conforti A, Esteves SC, Cimadomo D, Vaiarelli A, Di Rella F, Ubaldi FM, Zullo F, De Placido G, Alviggi C.

Front Endocrinol (Lausanne). 2019 Jun 27;10:387. doi: 10.3389/fendo.2019.00387. eCollection 2019. Review.


Pharmacogenetics of FSH Action in the Female.

Conforti A, Vaiarelli A, Cimadomo D, Bagnulo F, Peluso S, Carbone L, Di Rella F, De Placido G, Ubaldi FM, Huhtaniemi I, Alviggi C.

Front Endocrinol (Lausanne). 2019 Jun 26;10:398. doi: 10.3389/fendo.2019.00398. eCollection 2019. Review.


Looking past the appearance: a comprehensive description of the clinical contribution of poor-quality blastocysts to increase live birth rates during cycles with aneuploidy testing.

Cimadomo D, Soscia D, Vaiarelli A, Maggiulli R, Capalbo A, Ubaldi FM, Rienzi L.

Hum Reprod. 2019 Jul 8;34(7):1206-1214. doi: 10.1093/humrep/dez078.


The High Prevalence of Testicular Adrenal Rest Tumors in Adult Men With Congenital Adrenal Hyperplasia Is Correlated With ACTH Levels.

Mazzilli R, Stigliano A, Delfino M, Olana S, Zamponi V, Iorio C, Defeudis G, Cimadomo D, Toscano V, Mazzilli F.

Front Endocrinol (Lausanne). 2019 Jun 4;10:335. doi: 10.3389/fendo.2019.00335. eCollection 2019.


Embryonic cell-free DNA versus trophectoderm biopsy for aneuploidy testing: concordance rate and clinical implications.

Rubio C, Rienzi L, Navarro-Sánchez L, Cimadomo D, García-Pascual CM, Albricci L, Soscia D, Valbuena D, Capalbo A, Ubaldi F, Simón C.

Fertil Steril. 2019 Sep;112(3):510-519. doi: 10.1016/j.fertnstert.2019.04.038. Epub 2019 Jun 11.


The main will of the patients of a private Italian IVF clinic for their aneuploid/affected blastocysts would be donation to research: a currently forbidden choice.

Faustini F, Forte M, Capalbo A, Cimadomo D, Ubaldi FM, Rienzi L.

J Assist Reprod Genet. 2019 Aug;36(8):1555-1560. doi: 10.1007/s10815-019-01465-2. Epub 2019 May 27.


State of the art and emerging drug therapies for female infertility.

Venturella R, Vaiarelli A, Cimadomo D, Pedri S, Lico D, Mazzilli R, Mocciaro R, Rienzi L, Di Carlo C, Ubaldi FM, Zullo F.

Gynecol Endocrinol. 2019 Apr 29:1-7. doi: 10.1080/09513590.2019.1603289. [Epub ahead of print]


Perspectives in Gamete and Embryo Cryopreservation.

Rienzi LF, Iussig B, Dovere L, Fabozzi G, Cimadomo D, Ubaldi FM.

Semin Reprod Med. 2018 Sep;36(5):253-264. doi: 10.1055/s-0038-1677463. Epub 2019 Apr 4. Review.


Double stimulation in the same ovarian cycle (DuoStim) is an intriguing strategy to improve oocyte yield and the number of competent embryos in a short timeframe.

Vaiarelli A, Cimadomo D, Argento C, Ubaldi N, Trabucco E, Drakopoulos P, Venturella R, Conforti A, Alviggi C, Rienzi L, Ubaldi FM.

Minerva Ginecol. 2019 Oct;71(5):372-376. doi: 10.23736/S0026-4784.19.04390-9. Epub 2019 Mar 4.


Advanced Maternal Age in IVF: Still a Challenge? The Present and the Future of Its Treatment.

Ubaldi FM, Cimadomo D, Vaiarelli A, Fabozzi G, Venturella R, Maggiulli R, Mazzilli R, Ferrero S, Palagiano A, Rienzi L.

Front Endocrinol (Lausanne). 2019 Feb 20;10:94. doi: 10.3389/fendo.2019.00094. eCollection 2019. Review.


A brief history of oocyte cryopreservation: Arguments and facts.

Iussig B, Maggiulli R, Fabozzi G, Bertelle S, Vaiarelli A, Cimadomo D, Ubaldi FM, Rienzi L.

Acta Obstet Gynecol Scand. 2019 May;98(5):550-558. doi: 10.1111/aogs.13569. Epub 2019 Mar 25. Review.


An integrated investigation of oocyte developmental competence: expression of key genes in human cumulus cells, morphokinetics of early divisions, blastulation, and euploidy.

Scarica C, Cimadomo D, Dovere L, Giancani A, Stoppa M, Capalbo A, Ubaldi FM, Rienzi L, Canipari R.

J Assist Reprod Genet. 2019 May;36(5):875-887. doi: 10.1007/s10815-019-01410-3. Epub 2019 Feb 1.


Diagnostic efficacy of blastocoel fluid and spent media as sources of DNA for preimplantation genetic testing in standard clinical conditions.

Capalbo A, Romanelli V, Patassini C, Poli M, Girardi L, Giancani A, Stoppa M, Cimadomo D, Ubaldi FM, Rienzi L.

Fertil Steril. 2018 Oct;110(5):870-879.e5. doi: 10.1016/j.fertnstert.2018.05.031. Erratum in: Fertil Steril. 2019 Jan;111(1):194.


Biochemical pregnancy loss after frozen embryo transfer seems independent of embryo developmental stage and chromosomal status.

Vaiarelli A, Cimadomo D, Patrizio P, Venturella R, Orlando G, Soscia D, Giancani A, Capalbo A, Rienzi L, Ubaldi FM.

Reprod Biomed Online. 2018 Sep;37(3):349-357. doi: 10.1016/j.rbmo.2018.05.019. Epub 2018 Jun 30.


Associations of blastocyst features, trophectoderm biopsy and other laboratory practice with post-warming behavior and implantation.

Cimadomo D, Capalbo A, Levi-Setti PE, Soscia D, Orlando G, Albani E, Parini V, Stoppa M, Dovere L, Tacconi L, Ievoli E, Maggiulli R, Ubaldi FM, Rienzi L.

Hum Reprod. 2018 Nov 1;33(11):1992-2001. doi: 10.1093/humrep/dey291.


Inconclusive chromosomal assessment after blastocyst biopsy: prevalence, causative factors and outcomes after re-biopsy and re-vitrification. A multicenter experience.

Cimadomo D, Rienzi L, Romanelli V, Alviggi E, Levi-Setti PE, Albani E, Dusi L, Papini L, Livi C, Benini F, Smeraldi A, Patassini C, Ubaldi FM, Capalbo A.

Hum Reprod. 2018 Oct 1;33(10):1839-1846. doi: 10.1093/humrep/dey282.


Impact of Maternal Age on Oocyte and Embryo Competence.

Cimadomo D, Fabozzi G, Vaiarelli A, Ubaldi N, Ubaldi FM, Rienzi L.

Front Endocrinol (Lausanne). 2018 Jun 29;9:327. doi: 10.3389/fendo.2018.00327. eCollection 2018. Review.


Double Stimulation in the Same Ovarian Cycle (DuoStim) to Maximize the Number of Oocytes Retrieved From Poor Prognosis Patients: A Multicenter Experience and SWOT Analysis.

Vaiarelli A, Cimadomo D, Trabucco E, Vallefuoco R, Buffo L, Dusi L, Fiorini F, Barnocchi N, Bulletti FM, Rienzi L, Ubaldi FM.

Front Endocrinol (Lausanne). 2018 Jun 14;9:317. doi: 10.3389/fendo.2018.00317. eCollection 2018.


Luteal phase anovulatory follicles result in the production of competent oocytes: intra-patient paired case-control study comparing follicular versus luteal phase stimulations in the same ovarian cycle.

Cimadomo D, Vaiarelli A, Colamaria S, Trabucco E, Alviggi C, Venturella R, Alviggi E, Carmelo R, Rienzi L, Ubaldi FM.

Hum Reprod. 2018 Jun 15. doi: 10.1093/humrep/dey217. [Epub ahead of print]


Prevalence of XXY karyotypes in human blastocysts: multicentre data from 7549 trophectoderm biopsies obtained during preimplantation genetic testing cycles in IVF.

Mazzilli R, Cimadomo D, Rienzi L, Capalbo A, Levi Setti PE, Livi C, Vizziello D, Foresta C, Ferlin A, Ubaldi FM.

Hum Reprod. 2018 Jul 1;33(7):1355-1363. doi: 10.1093/humrep/dey110.


Continuous embryo culture elicits higher blastulation but similar cumulative delivery rates than sequential: a large prospective study.

Cimadomo D, Scarica C, Maggiulli R, Orlando G, Soscia D, Albricci L, Romano S, Sanges F, Ubaldi FM, Rienzi L.

J Assist Reprod Genet. 2018 Jul;35(7):1329-1338. doi: 10.1007/s10815-018-1195-4. Epub 2018 May 3.


What is new in the management of poor ovarian response in IVF?

Vaiarelli A, Cimadomo D, Ubaldi N, Rienzi L, Ubaldi FM.

Curr Opin Obstet Gynecol. 2018 Jun;30(3):155-162. doi: 10.1097/GCO.0000000000000452. Review.


Effect of the male factor on the clinical outcome of intracytoplasmic sperm injection combined with preimplantation aneuploidy testing: observational longitudinal cohort study of 1,219 consecutive cycles.

Mazzilli R, Cimadomo D, Vaiarelli A, Capalbo A, Dovere L, Alviggi E, Dusi L, Foresta C, Lombardo F, Lenzi A, Tournaye H, Alviggi C, Rienzi L, Ubaldi FM.

Fertil Steril. 2017 Dec;108(6):961-972.e3. doi: 10.1016/j.fertnstert.2017.08.033. Epub 2017 Oct 3.


Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging.

Capalbo A, Hoffmann ER, Cimadomo D, Ubaldi FM, Rienzi L.

Hum Reprod Update. 2017 Nov 1;23(6):706-722. doi: 10.1093/humupd/dmx026. Review.


Abnormally fertilized oocytes can result in healthy live births: improved genetic technologies for preimplantation genetic testing can be used to rescue viable embryos in in vitro fertilization cycles.

Capalbo A, Treff N, Cimadomo D, Tao X, Ferrero S, Vaiarelli A, Colamaria S, Maggiulli R, Orlando G, Scarica C, Scott R, Ubaldi FM, Rienzi L.

Fertil Steril. 2017 Dec;108(6):1007-1015.e3. doi: 10.1016/j.fertnstert.2017.08.004. Epub 2017 Sep 15.


Preimplantation genetic diagnosis for aneuploidy testing in women older than 44 years: a multicenter experience.

Ubaldi FM, Cimadomo D, Capalbo A, Vaiarelli A, Buffo L, Trabucco E, Ferrero S, Albani E, Rienzi L, Levi Setti PE.

Fertil Steril. 2017 May;107(5):1173-1180. doi: 10.1016/j.fertnstert.2017.03.007. Epub 2017 Apr 19.


Human Embryos Created by Embryo Splitting Secrete Significantly Lower Levels of miRNA-30c.

Noli L, Capalbo A, Dajani Y, Cimadomo D, Bvumbe J, Rienzi L, Ubaldi FM, Ogilvie C, Khalaf Y, Ilic D.

Stem Cells Dev. 2016 Dec 15;25(24):1853-1862. Epub 2016 Oct 17.


Pre-implantation genetic testing in ART: who will benefit and what is the evidence?

Vaiarelli A, Cimadomo D, Capalbo A, Orlando G, Sapienza F, Colamaria S, Palagiano A, Bulletti C, Rienzi L, Ubaldi FM.

J Assist Reprod Genet. 2016 Oct;33(10):1273-1278. Epub 2016 Aug 5. Review.


Implementing PGD/PGD-A in IVF clinics: considerations for the best laboratory approach and management.

Capalbo A, Romanelli V, Cimadomo D, Girardi L, Stoppa M, Dovere L, Dell'Edera D, Ubaldi FM, Rienzi L.

J Assist Reprod Genet. 2016 Oct;33(10):1279-1286. Epub 2016 Jul 16. Review.


Failure mode and effects analysis of witnessing protocols for ensuring traceability during PGD/PGS cycles.

Cimadomo D, Ubaldi FM, Capalbo A, Maggiulli R, Scarica C, Romano S, Poggiana C, Zuccarello D, Giancani A, Vaiarelli A, Rienzi L.

Reprod Biomed Online. 2016 Sep;33(3):360-9. doi: 10.1016/j.rbmo.2016.06.002. Epub 2016 Jun 23.


Generation of meiomaps of genome-wide recombination and chromosome segregation in human oocytes.

Ottolini CS, Capalbo A, Newnham L, Cimadomo D, Natesan SA, Hoffmann ER, Ubaldi FM, Rienzi L, Handyside AH.

Nat Protoc. 2016 Jul;11(7):1229-43. doi: 10.1038/nprot.2016.075. Epub 2016 Jun 16.


Follicular versus luteal phase ovarian stimulation during the same menstrual cycle (DuoStim) in a reduced ovarian reserve population results in a similar euploid blastocyst formation rate: new insight in ovarian reserve exploitation.

Ubaldi FM, Capalbo A, Vaiarelli A, Cimadomo D, Colamaria S, Alviggi C, Trabucco E, Venturella R, Vajta G, Rienzi L.

Fertil Steril. 2016 Jun;105(6):1488-1495.e1. doi: 10.1016/j.fertnstert.2016.03.002. Epub 2016 Mar 25.


The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis.

Cimadomo D, Capalbo A, Ubaldi FM, Scarica C, Palagiano A, Canipari R, Rienzi L.

Biomed Res Int. 2016;2016:7193075. doi: 10.1155/2016/7193075. Epub 2016 Jan 28. Review.


Consistent and reproducible outcomes of blastocyst biopsy and aneuploidy screening across different biopsy practitioners: a multicentre study involving 2586 embryo biopsies.

Capalbo A, Ubaldi FM, Cimadomo D, Maggiulli R, Patassini C, Dusi L, Sanges F, Buffo L, Venturella R, Rienzi L.

Hum Reprod. 2016 Jan;31(1):199-208. doi: 10.1093/humrep/dev294. Epub 2015 Dec 4.


MicroRNAs in spent blastocyst culture medium are derived from trophectoderm cells and can be explored for human embryo reproductive competence assessment.

Capalbo A, Ubaldi FM, Cimadomo D, Noli L, Khalaf Y, Farcomeni A, Ilic D, Rienzi L.

Fertil Steril. 2016 Jan;105(1):225-35.e1-3. doi: 10.1016/j.fertnstert.2015.09.014. Epub 2015 Oct 9.


Reduction of multiple pregnancies in the advanced maternal age population after implementation of an elective single embryo transfer policy coupled with enhanced embryo selection: pre- and post-intervention study.

Ubaldi FM, Capalbo A, Colamaria S, Ferrero S, Maggiulli R, Vajta G, Sapienza F, Cimadomo D, Giuliani M, Gravotta E, Vaiarelli A, Rienzi L.

Hum Reprod. 2015 Sep;30(9):2097-106. doi: 10.1093/humrep/dev159. Epub 2015 Jul 5.


Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates.

Ottolini CS, Newnham L, Capalbo A, Natesan SA, Joshi HA, Cimadomo D, Griffin DK, Sage K, Summers MC, Thornhill AR, Housworth E, Herbert AD, Rienzi L, Ubaldi FM, Handyside AH, Hoffmann ER.

Nat Genet. 2015 Jul;47(7):727-735. doi: 10.1038/ng.3306. Epub 2015 May 18.


Comparison of array comparative genomic hybridization and quantitative real-time PCR-based aneuploidy screening of blastocyst biopsies.

Capalbo A, Treff NR, Cimadomo D, Tao X, Upham K, Ubaldi FM, Rienzi L, Scott RT Jr.

Eur J Hum Genet. 2015 Jul;23(7):901-6. doi: 10.1038/ejhg.2014.222. Epub 2014 Oct 29.


Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centers involving 956 screened blastocysts.

Capalbo A, Rienzi L, Cimadomo D, Maggiulli R, Elliott T, Wright G, Nagy ZP, Ubaldi FM.

Hum Reprod. 2014 Jun;29(6):1173-81. doi: 10.1093/humrep/deu033. Epub 2014 Feb 26.


The NOBOX protein becomes undetectable in developmentally competent antral and ovulated oocytes.

Belli M, Cimadomo D, Merico V, Redi CA, Garagna S, Zuccotti M.

Int J Dev Biol. 2013;57(1):35-9. doi: 10.1387/ijdb.120125mz.

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