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Items: 1 to 50 of 87

1.

Dehydration assessment via portable, single sided magnetic resonance sensor.

Bashyam A, Frangieh CJ, Li M, Cima MJ.

Magn Reson Med. 2019 Oct 21. doi: 10.1002/mrm.28004. [Epub ahead of print]

PMID:
31631380
2.

An interventional image-guided microdevice implantation and retrieval method for in-vivo drug response assessment.

Bhagavatula SK, Upadhyaya K, Miller BJ, Bursch P, Lammers A, Cima MJ, Silverman SG, Jonas O.

Med Phys. 2019 Nov;46(11):5134-5143. doi: 10.1002/mp.13803. Epub 2019 Sep 26.

PMID:
31494942
3.

Fluid assessment in dialysis patients by point-of-care magnetic relaxometry.

Colucci LA, Corapi KM, Li M, Parada XV, Allegretti AS, Lin HY, Ausiello DA, Rosen MS, Cima MJ.

Sci Transl Med. 2019 Jul 24;11(502). pii: eaau1749. doi: 10.1126/scitranslmed.aau1749.

PMID:
31341060
4.

Steerable Microinvasive Probes for Localized Drug Delivery to Deep Tissue.

Cotler MJ, Rousseau EB, Ramadi KB, Fang J, Graybiel AM, Langer R, Cima MJ.

Small. 2019 Sep;15(37):e1901459. doi: 10.1002/smll.201901459. Epub 2019 Jun 11.

PMID:
31183933
5.

A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment.

Verma M, Vishwanath K, Eweje F, Roxhed N, Grant T, Castaneda M, Steiger C, Mazdiyasni H, Bensel T, Minahan D, Soares V, Salama JAF, Lopes A, Hess K, Cleveland C, Fulop DJ, Hayward A, Collins J, Tamang SM, Hua T, Ikeanyi C, Zeidman G, Mule E, Boominathan S, Popova E, Miller JB, Bellinger AM, Collins D, Leibowitz D, Batra S, Ahuja S, Bajiya M, Batra S, Sarin R, Agarwal U, Khaparde SD, Gupta NK, Gupta D, Bhatnagar AK, Chopra KK, Sharma N, Khanna A, Chowdhury J, Stoner R, Slocum AH, Cima MJ, Furin J, Langer R, Traverso G.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau6267. doi: 10.1126/scitranslmed.aau6267.

PMID:
30867322
6.

Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model.

Schwerdt HN, Zhang E, Kim MJ, Yoshida T, Stanwicks L, Amemori S, Dagdeviren HE, Langer R, Cima MJ, Graybiel AM.

Commun Biol. 2018 Sep 12;1:144. doi: 10.1038/s42003-018-0147-y. eCollection 2018.

7.

Cognitive predictors of reactive and proactive aggression in a forensic sample: A comparison with a non-clinical sample.

Brugman S, Lobbestael J, Sack AT, Cima MJ, Schuhmann T, Emmerling F, Arntz A.

Psychiatry Res. 2018 Nov;269:610-620. doi: 10.1016/j.psychres.2018.08.095. Epub 2018 Aug 31.

PMID:
30208350
8.

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy.

Jonas O, Kang JW, Singh SP, Lammers A, Nguyen FT, Dasari RR, So PTC, Langer R, Cima MJ.

Analyst. 2018 Oct 8;143(20):4836-4839. doi: 10.1039/c8an00913a.

9.

Focal, remote-controlled, chronic chemical modulation of brain microstructures.

Ramadi KB, Dagdeviren C, Spencer KC, Joe P, Cotler M, Rousseau E, Nunez-Lopez C, Graybiel AM, Langer R, Cima MJ.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7254-7259. doi: 10.1073/pnas.1804372115. Epub 2018 Jun 25.

10.

Design and experimental validation of Unilateral Linear Halbach magnet arrays for single-sided magnetic resonance.

Bashyam A, Li M, Cima MJ.

J Magn Reson. 2018 Jul;292:36-43. doi: 10.1016/j.jmr.2018.05.004. Epub 2018 May 9.

PMID:
29763794
11.

Affective traits of psychopathy are linked to white-matter abnormalities in impulsive male offenders.

Vermeij A, Kempes MM, Cima MJ, Mars RB, Brazil IA.

Neuropsychology. 2018 Sep;32(6):735-745. doi: 10.1037/neu0000448. Epub 2018 Apr 26.

PMID:
29697994
12.

Surface tension-assisted additive manufacturing.

Ragelle H, Tibbitt MW, Wu SY, Castillo MA, Cheng GZ, Gangadharan SP, Anderson DG, Cima MJ, Langer R.

Nat Commun. 2018 Mar 22;9(1):1184. doi: 10.1038/s41467-018-03391-w.

13.

Miniaturized neural system for chronic, local intracerebral drug delivery.

Dagdeviren C, Ramadi KB, Joe P, Spencer K, Schwerdt HN, Shimazu H, Delcasso S, Amemori KI, Nunez-Lopez C, Graybiel AM, Cima MJ, Langer R.

Sci Transl Med. 2018 Jan 24;10(425). pii: eaan2742. doi: 10.1126/scitranslmed.aan2742.

14.

Long-term dopamine neurochemical monitoring in primates.

Schwerdt HN, Shimazu H, Amemori KI, Amemori S, Tierney PL, Gibson DJ, Hong S, Yoshida T, Langer R, Cima MJ, Graybiel AM.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13260-13265. doi: 10.1073/pnas.1713756114. Epub 2017 Nov 20.

15.

Erratum: Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants.

Spencer KC, Sy JC, Ramadi KB, Graybiel AM, Langer R, Cima MJ.

Sci Rep. 2017 Oct 9;7(1):12812. doi: 10.1038/s41598-017-12312-8.

16.

Expanded Medicaid Provides Access to Substance Use, Mental Health, and Physician Visits to Homeless and Precariously Housed Persons.

Parker RD, Cima MJ, Brown Z, Regier M.

J Community Health. 2018 Apr;43(2):207-211. doi: 10.1007/s10900-017-0405-9.

PMID:
28707181
17.

Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants.

Spencer KC, Sy JC, Ramadi KB, Graybiel AM, Langer R, Cima MJ.

Sci Rep. 2017 May 16;7(1):1952. doi: 10.1038/s41598-017-02107-2. Erratum in: Sci Rep. 2017 Oct 9;7(1):12812.

18.

Ovarian cancer spheroid shrinkage following continuous exposure to cisplatin is a function of spheroid diameter.

Tanenbaum LM, Mantzavinou A, Subramanyam KS, Del Carmen MG, Cima MJ.

Gynecol Oncol. 2017 Jul;146(1):161-169. doi: 10.1016/j.ygyno.2017.04.014. Epub 2017 May 10.

PMID:
28499648
19.

Subcellular probes for neurochemical recording from multiple brain sites.

Schwerdt HN, Kim MJ, Amemori S, Homma D, Yoshida T, Shimazu H, Yerramreddy H, Karasan E, Langer R, Graybiel AM, Cima MJ.

Lab Chip. 2017 Mar 14;17(6):1104-1115. doi: 10.1039/c6lc01398h.

20.

A three dimensional in vitro glial scar model to investigate the local strain effects from micromotion around neural implants.

Spencer KC, Sy JC, Falcón-Banchs R, Cima MJ.

Lab Chip. 2017 Feb 28;17(5):795-804. doi: 10.1039/c6lc01411a.

21.

Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors.

Davidson SM, Jonas O, Keibler MA, Hou HW, Luengo A, Mayers JR, Wyckoff J, Del Rosario AM, Whitman M, Chin CR, Condon KJ, Lammers A, Kellersberger KA, Stall BK, Stephanopoulos G, Bar-Sagi D, Han J, Rabinowitz JD, Cima MJ, Langer R, Vander Heiden MG.

Nat Med. 2017 Feb;23(2):235-241. doi: 10.1038/nm.4256. Epub 2016 Dec 26.

22.

Adherence to HIV Treatment and Care at a Rural Appalachian HIV Clinic.

Parker RD, Mangine CM, Hendricks BM, Cima MJ, Mcie S, Sarwari A.

J Assoc Nurses AIDS Care. 2017 Jan - Feb;28(1):67-74. doi: 10.1016/j.jana.2016.09.002. Epub 2016 Sep 16.

PMID:
27742429
23.

Integrated genetic and pharmacologic interrogation of rare cancers.

Hong AL, Tseng YY, Cowley GS, Jonas O, Cheah JH, Kynnap BD, Doshi MB, Oh C, Meyer SC, Church AJ, Gill S, Bielski CM, Keskula P, Imamovic A, Howell S, Kryukov GV, Clemons PA, Tsherniak A, Vazquez F, Crompton BD, Shamji AF, Rodriguez-Galindo C, Janeway KA, Roberts CW, Stegmaier K, van Hummelen P, Cima MJ, Langer RS, Garraway LA, Schreiber SL, Root DE, Hahn WC, Boehm JS.

Nat Commun. 2016 Jun 22;7:11987. doi: 10.1038/ncomms11987.

24.

Parallel In Vivo Assessment of Drug Phenotypes at Various Time Points during Systemic BRAF Inhibition Reveals Tumor Adaptation and Altered Treatment Vulnerabilities.

Jonas O, Oudin MJ, Kosciuk T, Whitman M, Gertler FB, Cima MJ, Flaherty KT, Langer R.

Clin Cancer Res. 2016 Dec 15;22(24):6031-6038. Epub 2016 Apr 18.

25.

Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.

Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, Lauffenburger DA, Keely PJ, Bear JE, Gertler FB.

Cancer Discov. 2016 May;6(5):516-31. doi: 10.1158/2159-8290.CD-15-1183. Epub 2016 Jan 25.

26.

Sustained, low-dose intraperitoneal cisplatin improves treatment outcome in ovarian cancer mouse models.

Ye H, Tanenbaum LM, Na YJ, Mantzavinou A, Fulci G, Del Carmen MG, Birrer MJ, Cima MJ.

J Control Release. 2015 Dec 28;220(Pt A):358-367. doi: 10.1016/j.jconrel.2015.11.001. Epub 2015 Nov 5.

PMID:
26548976
27.

Depot delivery of dexamethasone and cediranib for the treatment of brain tumor associated edema in an intracranial rat glioma model.

Ong Q, Hochberg FH, Cima MJ.

J Control Release. 2015 Nov 10;217:183-90. doi: 10.1016/j.jconrel.2015.08.028. Epub 2015 Aug 15.

PMID:
26285064
28.

Miniaturized, biopsy-implantable chemical sensor with wireless, magnetic resonance readout.

Vassiliou CC, Liu VH, Cima MJ.

Lab Chip. 2015 Sep 7;15(17):3465-72. doi: 10.1039/c5lc00546a. Epub 2015 Jul 16.

PMID:
26177607
29.

(1)H nuclear magnetic resonance (NMR) as a tool to measure dehydration in mice.

Li M, Vassiliou CC, Colucci LA, Cima MJ.

NMR Biomed. 2015 Aug;28(8):1031-9. doi: 10.1002/nbm.3334. Epub 2015 Jun 30.

PMID:
26123278
30.

If It's Not One Thing, It's Another: An Inverse Relationship of Malignancy and Atherosclerotic Disease.

Li M, Cima MJ, Milner DA Jr.

PLoS One. 2015 May 22;10(5):e0126855. doi: 10.1371/journal.pone.0126855. eCollection 2015.

31.

An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors.

Jonas O, Landry HM, Fuller JE, Santini JT Jr, Baselga J, Tepper RI, Cima MJ, Langer R.

Sci Transl Med. 2015 Apr 22;7(284):284ra57. doi: 10.1126/scitranslmed.3010564.

32.

Next-generation wearable electronics.

Cima MJ.

Nat Biotechnol. 2014 Jul;32(7):642-3. doi: 10.1038/nbt.2952. No abstract available.

PMID:
25004232
33.

Single compartment drug delivery.

Cima MJ, Lee H, Daniel K, Tanenbaum LM, Mantzavinou A, Spencer KC, Ong Q, Sy JC, Santini J Jr, Schoellhammer CM, Blankschtein D, Langer RS.

J Control Release. 2014 Sep 28;190:157-71. doi: 10.1016/j.jconrel.2014.04.049. Epub 2014 May 4. Review.

34.

Solid MRI contrast agents for long-term, quantitative in vivo oxygen sensing.

Liu VH, Vassiliou CC, Imaad SM, Cima MJ.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6588-93. doi: 10.1073/pnas.1400015111. Epub 2014 Apr 21.

35.

Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.

Milwid JM, Elman JS, Li M, Shen K, Manrai A, Gabow A, Yarmush J, Jiao Y, Fletcher A, Lee J, Cima MJ, Yarmush ML, Parekkadan B.

Mol Ther. 2014 May;22(5):999-1007. doi: 10.1038/mt.2014.17. Epub 2014 Feb 5.

36.

Intracranial MEMS based temozolomide delivery in a 9L rat gliosarcoma model.

Masi BC, Tyler BM, Bow H, Wicks RT, Xue Y, Brem H, Langer R, Cima MJ.

Biomaterials. 2012 Aug;33(23):5768-75. doi: 10.1016/j.biomaterials.2012.04.048. Epub 2012 May 14.

37.

First-in-human testing of a wirelessly controlled drug delivery microchip.

Farra R, Sheppard NF Jr, McCabe L, Neer RM, Anderson JM, Santini JT Jr, Cima MJ, Langer R.

Sci Transl Med. 2012 Feb 22;4(122):122ra21. doi: 10.1126/scitranslmed.3003276. Epub 2012 Feb 16.

38.

Implantable magnetic relaxation sensors measure cumulative exposure to cardiac biomarkers.

Ling Y, Pong T, Vassiliou CC, Huang PL, Cima MJ.

Nat Biotechnol. 2011 Mar;29(3):273-7. doi: 10.1038/nbt.1780. Epub 2011 Feb 13.

PMID:
21317907
39.

Intracranial microcapsule drug delivery device for the treatment of an experimental gliosarcoma model.

Scott AW, Tyler BM, Masi BC, Upadhyay UM, Patta YR, Grossman R, Basaldella L, Langer RS, Brem H, Cima MJ.

Biomaterials. 2011 Apr;32(10):2532-9. doi: 10.1016/j.biomaterials.2010.12.020. Epub 2011 Jan 8.

PMID:
21220172
40.

Microsystem technologies for medical applications.

Cima MJ.

Annu Rev Chem Biomol Eng. 2011;2:355-78. doi: 10.1146/annurev-chembioeng-061010-114120. Review.

PMID:
22432623
41.

An intravesical device for the sustained delivery of lidocaine to the bladder.

Lee H, Cima MJ.

J Control Release. 2011 Jan 20;149(2):133-9. doi: 10.1016/j.jconrel.2010.10.016. Epub 2010 Oct 30.

PMID:
20971144
42.

Electro-thermally induced structural failure actuator (ETISFA) for implantable controlled drug delivery devices based on micro-electro-mechanical-systems.

Elman NM, Masi BC, Cima MJ, Langer R.

Lab Chip. 2010 Oct 21;10(20):2796-804. doi: 10.1039/c005135g. Epub 2010 Aug 27.

PMID:
20820485
43.

Scaling of transverse nuclear magnetic relaxation due to magnetic nanoparticle aggregation.

Brown KA, Vassiliou CC, Issadore D, Berezovsky J, Cima MJ, Westervelt RM.

J Magn Magn Mater. 2010 Oct 1;322(20):3122-3126.

44.

Magnetic relaxation-based platform for multiplexed assays.

Ling Y, Vassiliou CC, Cima MJ.

Analyst. 2010 Sep;135(9):2360-4. doi: 10.1039/b926041m. Epub 2010 Jul 13.

PMID:
20625581
45.

Zero-order controlled release of ciprofloxacin-HCl from a reservoir-based, bioresorbable and elastomeric device.

Tobias IS, Lee H, Engelmayr GC Jr, Macaya D, Bettinger CJ, Cima MJ.

J Control Release. 2010 Sep 15;146(3):356-62. doi: 10.1016/j.jconrel.2010.05.036. Epub 2010 Jun 4.

46.

Implantable diagnostic device for cancer monitoring.

Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ.

Biosens Bioelectron. 2009 Jul 15;24(11):3252-7. doi: 10.1016/j.bios.2009.04.010. Epub 2009 Apr 16.

47.

The next generation of drug-delivery microdevices.

Elman NM, Patta Y, Scott AW, Masi B, Ho Duc HL, Cima MJ.

Clin Pharmacol Ther. 2009 May;85(5):544-7. doi: 10.1038/clpt.2009.4. Epub 2009 Feb 25. No abstract available.

PMID:
19242402
48.

An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care.

Elman NM, Ho Duc HL, Cima MJ.

Biomed Microdevices. 2009 Jun;11(3):625-31. doi: 10.1007/s10544-008-9272-6.

PMID:
19169826
49.

Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy.

Wang AZ, Bagalkot V, Vasilliou CC, Gu F, Alexis F, Zhang L, Shaikh M, Yuet K, Cima MJ, Langer R, Kantoff PW, Bander NH, Jon S, Farokhzad OC.

ChemMedChem. 2008 Sep;3(9):1311-5. doi: 10.1002/cmdc.200800091. No abstract available.

50.

Magnetic microparticle aggregation for viscosity determination by MR.

Hong R, Cima MJ, Weissleder R, Josephson L.

Magn Reson Med. 2008 Mar;59(3):515-20. doi: 10.1002/mrm.21526.

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