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Items: 5

1.

Trehalose- and glucose-derived glycoamphiphiles: small-molecule and nanoparticle Toll-like receptor 4 (TLR4) modulators.

Rodriguez Lavado J, Sestito SE, Cighetti R, Aguilar Moncayo EM, Oblak A, Lainšček D, Jiménez Blanco JL, García Fernández JM, Ortiz Mellet C, Jerala R, Calabrese V, Peri F.

J Med Chem. 2014 Nov 13;57(21):9105-23. doi: 10.1021/jm501182w. Epub 2014 Oct 21.

PMID:
25268544
2.

Molecular simplification of lipid A structure: TLR4-modulating cationic and anionic amphiphiles.

Calabrese V, Cighetti R, Peri F.

Mol Immunol. 2015 Feb;63(2):153-61. doi: 10.1016/j.molimm.2014.05.011. Epub 2014 Jun 14. Review.

PMID:
24939379
3.

Modulation of CD14 and TLR4·MD-2 activities by a synthetic lipid A mimetic.

Cighetti R, Ciaramelli C, Sestito SE, Zanoni I, Kubik Ł, Ardá-Freire A, Calabrese V, Granucci F, Jerala R, Martín-Santamaría S, Jiménez-Barbero J, Peri F.

Chembiochem. 2014 Jan 24;15(2):250-8. doi: 10.1002/cbic.201300588. Epub 2013 Dec 12.

4.

A synthetic lipid A mimetic modulates human TLR4 activity.

Piazza M, Calabrese V, Damore G, Cighetti R, Gioannini T, Weiss J, Peri F.

ChemMedChem. 2012 Feb 6;7(2):213-7. doi: 10.1002/cmdc.201100494. Epub 2011 Dec 2. No abstract available.

5.

Exploring the LPS/TLR4 signal pathway with small molecules.

Peri F, Piazza M, Calabrese V, Damore G, Cighetti R.

Biochem Soc Trans. 2010 Oct;38(5):1390-5. doi: 10.1042/BST0381390. Review.

PMID:
20863319

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