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Items: 18


ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice.

Zitomersky NL, Demers M, Martinod K, Gallant M, Cifuni SM, Biswas A, Snapper S, Wagner DD.

TH Open. 2017 Jun;1(1):e11-e23. doi: 10.1055/s-0037-1603927.


Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice.

Hayashi H, Cherpokova D, Martinod K, Witsch T, Wong SL, Gallant M, Cifuni SM, Guarente LP, Wagner DD.

PLoS One. 2017 Dec 13;12(12):e0188341. doi: 10.1371/journal.pone.0188341. eCollection 2017.


Peptidylarginine deiminase 4 promotes age-related organ fibrosis.

Martinod K, Witsch T, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, Gallant M, Mauler M, Cifuni SM, Wagner DD.

J Exp Med. 2017 Feb;214(2):439-458. doi: 10.1084/jem.20160530. Epub 2016 Dec 28.


ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor-Induced Thrombotic Microangiopathy.

Erpenbeck L, Demers M, Zsengellér ZK, Gallant M, Cifuni SM, Stillman IE, Karumanchi SA, Wagner DD.

J Am Soc Nephrol. 2016 Jan;27(1):120-31. doi: 10.1681/ASN.2014121165. Epub 2015 Jun 2.


P-selectin promotes neutrophil extracellular trap formation in mice.

Etulain J, Martinod K, Wong SL, Cifuni SM, Schattner M, Wagner DD.

Blood. 2015 Jul 9;126(2):242-6. doi: 10.1182/blood-2015-01-624023. Epub 2015 May 15.


Endothelial Von Willebrand factor promotes blood-brain barrier flexibility and provides protection from hypoxia and seizures in mice.

Suidan GL, Brill A, De Meyer SF, Voorhees JR, Cifuni SM, Cabral JE, Wagner DD.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2112-20. doi: 10.1161/ATVBAHA.113.301362. Epub 2013 Jul 3.


Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.

Duerschmied D, Suidan GL, Demers M, Herr N, Carbo C, Brill A, Cifuni SM, Mauler M, Cicko S, Bader M, Idzko M, Bode C, Wagner DD.

Blood. 2013 Feb 7;121(6):1008-15. doi: 10.1182/blood-2012-06-437392. Epub 2012 Dec 12.


Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice.

Thomas GM, Carbo C, Curtis BR, Martinod K, Mazo IB, Schatzberg D, Cifuni SM, Fuchs TA, von Andrian UH, Hartwig JH, Aster RH, Wagner DD.

Blood. 2012 Jun 28;119(26):6335-43. doi: 10.1182/blood-2012-01-405183. Epub 2012 May 17.


Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.

Jansen AJ, Josefsson EC, Rumjantseva V, Liu QP, Falet H, Bergmeier W, Cifuni SM, Sackstein R, von Andrian UH, Wagner DD, Hartwig JH, Hoffmeister KM.

Blood. 2012 Feb 2;119(5):1263-73. doi: 10.1182/blood-2011-05-355628. Epub 2011 Nov 18.


Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis.

Carbo C, Duerschmied D, Goerge T, Hattori H, Sakai J, Cifuni SM, White GC 2nd, Chrzanowska-Wodnicka M, Luo HR, Wagner DD.

J Leukoc Biol. 2010 Aug;88(2):313-9. doi: 10.1189/jlb.0110049. Epub 2010 Apr 22.


p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo.

Canault M, Duerschmied D, Brill A, Stefanini L, Schatzberg D, Cifuni SM, Bergmeier W, Wagner DD.

Blood. 2010 Mar 4;115(9):1835-42. doi: 10.1182/blood-2009-03-211706. Epub 2009 Nov 30.


Innate immune cells induce hemorrhage in tumors during thrombocytopenia.

Ho-Tin-Noé B, Carbo C, Demers M, Cifuni SM, Goerge T, Wagner DD.

Am J Pathol. 2009 Oct;175(4):1699-708. doi: 10.2353/ajpath.2009.090460. Epub 2009 Sep 3.


Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17).

Duerschmied D, Canault M, Lievens D, Brill A, Cifuni SM, Bader M, Wagner DD.

J Thromb Haemost. 2009 Jul;7(7):1163-71. doi: 10.1111/j.1538-7836.2009.03476.x. Epub 2009 May 8.


Platelet granule secretion continuously prevents intratumor hemorrhage.

Ho-Tin-Noé B, Goerge T, Cifuni SM, Duerschmied D, Wagner DD.

Cancer Res. 2008 Aug 15;68(16):6851-8. doi: 10.1158/0008-5472.CAN-08-0718.


CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in platelets.

Cifuni SM, Wagner DD, Bergmeier W.

Blood. 2008 Sep 1;112(5):1696-703. doi: 10.1182/blood-2008-02-139733. Epub 2008 Jun 10.


Inflammation induces hemorrhage in thrombocytopenia.

Goerge T, Ho-Tin-Noe B, Carbo C, Benarafa C, Remold-O'Donnell E, Zhao BQ, Cifuni SM, Wagner DD.

Blood. 2008 May 15;111(10):4958-64. doi: 10.1182/blood-2007-11-123620. Epub 2008 Feb 6.


Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.

Bergmeier W, Goerge T, Wang HW, Crittenden JR, Baldwin AC, Cifuni SM, Housman DE, Graybiel AM, Wagner DD.

J Clin Invest. 2007 Jun;117(6):1699-707. Epub 2007 May 10.


The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis.

Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16900-5. Epub 2006 Oct 30.

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