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Items: 13

1.

The Role of NADPH Oxidases in the Etiology of Obesity and Metabolic Syndrome: Contribution of Individual Isoforms and Cell Biology.

DeVallance E, Li Y, Jurczak MJ, Cifuentes-Pagano E, Pagano PJ.

Antioxid Redox Signal. 2019 Oct 1;31(10):687-709. doi: 10.1089/ars.2018.7674.

PMID:
31250671
2.

Rational Design and Delivery of NOX-Inhibitory Peptides.

Cifuentes-Pagano E, Pagano PJ.

Methods Mol Biol. 2019;1982:417-428. doi: 10.1007/978-1-4939-9424-3_24.

PMID:
31172486
3.

Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities.

Harmon DB, Mandler WK, Sipula IJ, Dedousis N, Lewis SE, Eckels JT, Du J, Wang Y, Huckestein BR, Pagano PJ, Cifuentes-Pagano E, Homanics GE, Van't Erve TJ, Stefanovic-Racic M, Jurczak MJ, O'Doherty RM, Kelley EE.

Diabetes. 2019 Jun;68(6):1221-1229. doi: 10.2337/db18-1198. Epub 2019 Apr 1.

4.

NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow.

Li Y, Cifuentes-Pagano E, DeVallance ER, de Jesus DS, Sahoo S, Meijles DN, Koes D, Camacho CJ, Ross M, St Croix C, Pagano PJ.

Redox Biol. 2019 Apr;22:101143. doi: 10.1016/j.redox.2019.101143. Epub 2019 Feb 15.

5.
6.

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.

Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ.

Redox Biol. 2018 Jul;17:259-273. doi: 10.1016/j.redox.2018.04.007. Epub 2018 Apr 13.

7.

The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.

Meijles DN, Sahoo S, Al Ghouleh I, Amaral JH, Bienes-Martinez R, Knupp HE, Attaran S, Sembrat JC, Nouraie SM, Rojas MM, Novelli EM, Gladwin MT, Isenberg JS, Cifuentes-Pagano E, Pagano PJ.

Sci Signal. 2017 Oct 17;10(501). pii: eaaj1784. doi: 10.1126/scisignal.aaj1784.

8.

MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension.

Sahoo S, Meijles DN, Al Ghouleh I, Tandon M, Cifuentes-Pagano E, Sembrat J, Rojas M, Goncharova E, Pagano PJ.

PLoS One. 2016 May 4;11(5):e0153780. doi: 10.1371/journal.pone.0153780. eCollection 2016.

9.

Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors.

Cifuentes-Pagano E, Saha J, Csányi G, Ghouleh IA, Sahoo S, Rodríguez A, Wipf P, Pagano PJ, Skoda EM.

Medchemcomm. 2013 Jul;4(7):1085-1092.

10.

The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfalls.

Cifuentes-Pagano E, Meijles DN, Pagano PJ.

Antioxid Redox Signal. 2014 Jun 10;20(17):2741-54. doi: 10.1089/ars.2013.5620. Epub 2013 Dec 14. Review.

11.

NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS.

Cifuentes-Pagano E, Csanyi G, Pagano PJ.

Cell Mol Life Sci. 2012 Jul;69(14):2315-25. doi: 10.1007/s00018-012-1009-2. Epub 2012 May 15. Review.

12.

Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling.

Al Ghouleh I, Khoo NK, Knaus UG, Griendling KK, Touyz RM, Thannickal VJ, Barchowsky A, Nauseef WM, Kelley EE, Bauer PM, Darley-Usmar V, Shiva S, Cifuentes-Pagano E, Freeman BA, Gladwin MT, Pagano PJ.

Free Radic Biol Med. 2011 Oct 1;51(7):1271-88. doi: 10.1016/j.freeradbiomed.2011.06.011. Epub 2011 Jun 14. Review.

13.

Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2.

Csányi G, Cifuentes-Pagano E, Al Ghouleh I, Ranayhossaini DJ, Egaña L, Lopes LR, Jackson HM, Kelley EE, Pagano PJ.

Free Radic Biol Med. 2011 Sep 15;51(6):1116-25. doi: 10.1016/j.freeradbiomed.2011.04.025. Epub 2011 Apr 17.

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